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Journal Articles

Abstract 945: Live attenuated MMR vaccines modulate tumor immune cell infiltration and synergize with standard of care to prolong survival in preclinical HCC models

Mulu Z. Tesfay, Aleksandra Cios, Khandoker U. Ferdous, Randal S. Shelton, Bahaa Mustafa, Camila C. Simoes, Steven Post, Thomas Kelly, Moaven Moaven, Lewis R. Roberts, Mitesh J. Borad, Martin J. Cannon, Alexei Basnakian, Nagalo Bolni

Cancer Res (2025) 85 (8_Supplement_1): 945.

https://doi.org/10.1158/1538-7445.AM2025-945

Published: 21 April 2025

View articletitled, Abstract 945: Live attenuated MMR vaccines modulate tumor immune cell infiltration and synergize with standard of care to prolong survival in preclinical HCC models

Journal Articles

Abstract 6525: Modulating the immune response in cholangiocarcinoma: Targeting sulfatase-2 for therapeutic intervention

Tayla R. Brooks, Nellie Campbell, Melanie Keim, Lewis R. Roberts

Cancer Res (2024) 84 (6_Supplement): 6525.

https://doi.org/10.1158/1538-7445.AM2024-6525

Published: 22 March 2024

View articletitled, Abstract 6525: Modulating the immune response in cholangiocarcinoma: Targeting sulfatase-2 for therapeutic intervention

Journal Articles

Abstract 5228: Genome-wide association study and LD score regression analysis for cholangiocarcinoma

Younghun Han, Katherine A. McGlynn, Jinyoung Byun, Matthew A. Cooley, Manal M. Hassan, Christopher I. Amos, Lewis R. Roberts, The International Consortium for the Genetics of Biliary Tract Cancers

Cancer Res (2023) 83 (7_Supplement): 5228.

https://doi.org/10.1158/1538-7445.AM2023-5228

Published: 04 April 2023

View articletitled, Abstract 5228: Genome-wide association study and LD score regression analysis for cholangiocarcinoma

Journal Articles

Abstract 5489: Synergistic activity of SCD1 blockade in combination with tyrosine kinase inhibitors lenvatinib and cabozantinib in hepatocellular carcinoma (HCC)

Justyna J. Gleba, Aylin Alasonyalilar-Demirer, Matthew L. Pawlush, Ahmet Bilgili, Peyton G. Hickman, Kabir Mody, Lewis R. Roberts, Steven R. Alberts, Mark J. Truty, Tushar C. Patel, Han W. Tun, John A. Copland

Cancer Res (2023) 83 (7_Supplement): 5489.

https://doi.org/10.1158/1538-7445.AM2023-5489

Published: 04 April 2023

View articletitled, Abstract 5489: Synergistic activity of SCD1 blockade in combination with tyrosine kinase inhibitors lenvatinib and cabozantinib in hepatocellular carcinoma (HCC)

Journal Articles

Abstract 6013: DNA methylation-based inflammation score is associated with hepatocellular carcinoma among people living with HIV

Cancer Res (2023) 83 (7_Supplement): 6013.

https://doi.org/10.1158/1538-7445.AM2023-6013

Published: 04 April 2023

View articletitled, Abstract 6013: DNA methylation-based inflammation score is associated with hepatocellular carcinoma among people living with HIV

Journal Articles

Abstract 413: Preclinical efficacy of platinum based chemotherapy regimens and targeted therapeutics in the first successful described patient derived xenograft model of mixed acinar neuroendocrine carcinoma of the pancreas

Amro M. Abdelrahman, Jennifer A. Yonkus, Roberto Alva-Ruiz, Jennifer L. Leiting, Nellie A. Campbell, Lewis R. Roberts, Michael L. Kendrick, David M. Nagorney, Sean P. Cleary, Travis E. Grotz, Gregory J. Gores, Jun Yin, Rondell P. Graham, Thorvardur R. Halfdanarson, Rory L. Smoot, Mark J. Truty

Cancer Res (2021) 81 (13_Supplement): 413.

https://doi.org/10.1158/1538-7445.AM2021-413

Published: 01 July 2021

View articletitled, Abstract 413: Preclinical efficacy of platinum based chemotherapy regimens and targeted therapeutics in the first successful described patient derived xenograft model of mixed acinar neuroendocrine carcinoma of the pancreas

Journal Articles

Abstract 1004: Defining stearoyl-CoA desaturase 1 as a molecular therapeutic target against cholangiocarcinoma

Justyna J. Gleba, Laura A. Marlow, Erin E. Miller, James L. Miller, Aylin Alasonyalilar-Demirer, Yi Guo, Kabir Mody, Lewis R. Roberts, Steven R. Alberts, Mark J. Truty, Tushar C. Patel, John A. Copland

Cancer Res (2021) 81 (13_Supplement): 1004.

https://doi.org/10.1158/1538-7445.AM2021-1004

Published: 01 July 2021

View articletitled, Abstract 1004: Defining stearoyl-CoA desaturase 1 as a molecular therapeutic target against cholangiocarcinoma

Journal Articles

Abstract 3078: Effects of upamostat and opaganib on cholangiocarcinoma patient derived xenografts

Faizal Z. Asumda, Mohamed A. Hassan, Yo Han Kim, Nellie A. Campbell, Xin Luo, Daniel R. O'Brien, Sarah A. Buhrow, Joel M. Reid, Michael J. Moore, Vered Katz Ben-Yair, Reza Fathi, Mark L. Levitt, Fabrice Lucien-Matteoni, Jennifer L. Leiting, Mark J. Truty, Lewis R. Roberts

Cancer Res (2020) 80 (16_Supplement): 3078.

https://doi.org/10.1158/1538-7445.AM2020-3078

Published: 15 August 2020

View articletitled, Abstract 3078: Effects of upamostat and opaganib on cholangiocarcinoma patient derived xenografts

Journal Articles

Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma

Cancer Res (2019) 79 (17): 4326–4330.

https://doi.org/10.1158/0008-5472.CAN-19-0803

Published: 03 September 2019

View articletitled, Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma

Journal Articles

Abstract 5049: Associations of aspirin, non-aspirin NSAIDs, statins, and metformin with risk of biliary tract cancer: A Swedish population-based cohort study

Lorena Marcano-Bonilla, Cathy D. Schleck, W. Scott Harmsen, Omid Sadr-Azodi, Mitesh J. Borad, Tushar Patel, Gloria M. Petersen, Terry M. Therneau, Lewis R. Roberts, Nele Brusselaers

Cancer Res (2019) 79 (13_Supplement): 5049.

https://doi.org/10.1158/1538-7445.AM2019-5049

Published: 01 July 2019

View articletitled, Abstract 5049: Associations of aspirin, non-aspirin NSAIDs, statins, and metformin with risk of biliary tract cancer: A Swedish population-based cohort study

Journal Articles

Abstract LB-235: DNA methylation of individual repetitive elements in HCV infection-induced HCC

Yinan Zheng, Jimmy Ren, Ryan A. Hlady, Keith D. Robertson, Robert L. Murphy, Lewis R. Roberts, Lifang Hou

Cancer Res (2018) 78 (13_Supplement): LB-235.

https://doi.org/10.1158/1538-7445.AM2018-LB-235

Published: 01 July 2018

View articletitled, Abstract LB-235: DNA methylation of individual repetitive elements in HCV infection-induced HCC

Journal Articles

Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Cancer Res (2017) 77 (23): 6576–6588.

https://doi.org/10.1158/0008-5472.CAN-17-2281

Published: 30 November 2017

View articletitled, Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Includes: Supplementary data

Journal Articles

Abstract 192: Targeting stearoyl CoA desaturase 1 (SCD1) in hepatobilliary carcinoma

John Alton Copland, Laura A. Marlow, Ilah Bok, James L. Miller, Matsuda Akiko, Yan W. Asmann, Vivekananda Sarangi, Steven R. Alberts, Kabir Mody, Lewis R. Roberts, Mark J. Truty, Tushar C. Patel

Cancer Res (2017) 77 (13_Supplement): 192.

https://doi.org/10.1158/1538-7445.AM2017-192

Published: 01 July 2017

View articletitled, Abstract 192: Targeting stearoyl CoA desaturase 1 (SCD1) in hepatobilliary carcinoma

Journal Articles

Transcriptional Induction of Periostin by a Sulfatase 2–TGFβ1–SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma

Cancer Res (2017) 77 (3): 632–645.

https://doi.org/10.1158/0008-5472.CAN-15-2556

Published: 31 January 2017

View articletitled, Transcriptional Induction of Periostin by a Sulfatase 2–TGFβ1–SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma

Includes: Supplementary data

Journal Articles

Abstract LB-183: Metformin use does not increase survival of pancreatic cancer patients: A cautionary lesson

Roongruedee Chaiteerakij, David B. Zhen, Patrick A. Burch, Kari G. Chaffee, William R. Bamlet, Ann L. Oberg, Lewis R. Roberts, Gloria M. Petersen

Cancer Res (2015) 75 (15_Supplement): LB-183.

https://doi.org/10.1158/1538-7445.AM2015-LB-183

Published: 01 August 2015

View articletitled, Abstract LB-183: Metformin use does not increase survival of pancreatic cancer patients: A cautionary lesson

Journal Articles

Abstract 3745: Comprehensive integrative characterization of hepatocellular carcinoma: The TCGA HCC project

Lewis R. Roberts, David A. Wheeler

Cancer Res (2015) 75 (15_Supplement): 3745.

https://doi.org/10.1158/1538-7445.AM2015-3745

Published: 01 August 2015

View articletitled, Abstract 3745: Comprehensive integrative characterization of hepatocellular carcinoma: The TCGA HCC project

Journal Articles

Abstract 4252: Accurate site prediction of gastrointestinal cancer by novel methylated DNA markers: Discovery & validation

John B. Kisiel, William R. Taylor, Tracy C. Yab, Hassan M. Ghoz, Patrick H. Foote, Mary E. Devens, Douglas W. Mahoney, Thomas C. Smyrk, Lisa A. Boardman, Gloria M. Petersen, Navtej S. Buttar, Lewis R. Roberts, Graham P. Lidgard, David A. Ahlquist

Cancer Res (2015) 75 (15_Supplement): 4252.

https://doi.org/10.1158/1538-7445.AM2015-4252

Published: 01 August 2015

View articletitled, Abstract 4252: Accurate site prediction of gastrointestinal cancer by novel methylated DNA markers: Discovery & validation

Journal Articles

Therapeutic Effects of Deleting Cancer-Associated Fibroblasts in Cholangiocarcinoma

Joachim C. Mertens, Christian D. Fingas, John D. Christensen, Rory L. Smoot, Steven F. Bronk, Nathan W. Werneburg, Michael P. Gustafson, Allan B. Dietz, Lewis R. Roberts, Alphonse E. Sirica, Gregory J. Gores

Cancer Res (2013) 73 (2): 897–907.

https://doi.org/10.1158/0008-5472.CAN-12-2130

Published: 16 January 2013

View articletitled, Therapeutic Effects of Deleting Cancer-Associated Fibroblasts in Cholangiocarcinoma

Includes: Supplementary data

Journal Articles

Abstract 4905: The BH3 mimetic navitoclax (ABT-263) selectively induces apoptosis in cholangiocarcinoma-associated fibroblasts thereby reducing tumor growth

Joachim C. Mertens, Christian D. Fingas, John D. Christensen, Keisuke Kakisaka, Rory L. Smoot, Steven F. Bronk, Justin L. Mott, Michael P. Gustafson, Allan B. Dietz, Lewis R. Roberts, Alphonse E. Sirica, Gregory J. Gores

Cancer Res (2012) 72 (8_Supplement): 4905.

https://doi.org/10.1158/1538-7445.AM2012-4905

Published: 15 April 2012

View articletitled, Abstract 4905: The BH3 mimetic navitoclax (ABT-263) selectively induces apoptosis in cholangiocarcinoma-associated fibroblasts thereby reducing tumor growth

Journal Articles

Abstract 1058: Mutations in isocitrate dehydrogenase 1 and 2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas

Cancer Res (2012) 72 (8_Supplement): 1058.

https://doi.org/10.1158/1538-7445.AM2012-1058

Published: 15 April 2012

View articletitled, Abstract 1058: Mutations in isocitrate dehydrogenase 1 and 2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas

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Abstract 945: Live attenuated MMR vaccines modulate tumor immune cell infiltration and synergize with standard of care to prolong survival in preclinical HCC models

Abstract 6525: Modulating the immune response in cholangiocarcinoma: Targeting sulfatase-2 for therapeutic intervention

Abstract 5228: Genome-wide association study and LD score regression analysis for cholangiocarcinoma

Abstract 5489: Synergistic activity of SCD1 blockade in combination with tyrosine kinase inhibitors lenvatinib and cabozantinib in hepatocellular carcinoma (HCC)

Abstract 6013: DNA methylation-based inflammation score is associated with hepatocellular carcinoma among people living with HIV

Abstract 413: Preclinical efficacy of platinum based chemotherapy regimens and targeted therapeutics in the first successful described patient derived xenograft model of mixed acinar neuroendocrine carcinoma of the pancreas

Abstract 1004: Defining stearoyl-CoA desaturase 1 as a molecular therapeutic target against cholangiocarcinoma

Abstract 3078: Effects of upamostat and opaganib on cholangiocarcinoma patient derived xenografts

Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma

Abstract 5049: Associations of aspirin, non-aspirin NSAIDs, statins, and metformin with risk of biliary tract cancer: A Swedish population-based cohort study

Abstract LB-235: DNA methylation of individual repetitive elements in HCV infection-induced HCC

Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Abstract 192: Targeting stearoyl CoA desaturase 1 (SCD1) in hepatobilliary carcinoma

Transcriptional Induction of Periostin by a Sulfatase 2–TGFβ1–SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma

Abstract LB-183: Metformin use does not increase survival of pancreatic cancer patients: A cautionary lesson

Abstract 3745: Comprehensive integrative characterization of hepatocellular carcinoma: The TCGA HCC project

Abstract 4252: Accurate site prediction of gastrointestinal cancer by novel methylated DNA markers: Discovery & validation

Therapeutic Effects of Deleting Cancer-Associated Fibroblasts in Cholangiocarcinoma

Abstract 4905: The BH3 mimetic navitoclax (ABT-263) selectively induces apoptosis in cholangiocarcinoma-associated fibroblasts thereby reducing tumor growth

Abstract 1058: Mutations in isocitrate dehydrogenase 1 and 2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas

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