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Journal Articles

Abstract CT111: Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa

Cancer Res (2020) 80 (16_Supplement): CT111.

https://doi.org/10.1158/1538-7445.AM2020-CT111

Published: 15 August 2020

View article titled, Abstract CT111: Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa

Journal Articles

Abstract 5241: Nitric oxide-releasing naproxen prevents muscle invasive bladder cancer

Venkateshwar Madka, Altaf Mohammed, Qian Li, Yuting Zhang, Stanley Lightfoot, Xue-Ru Wu, Vernon Steele, Levy Kopelovich, Chinthalapally V. Rao

Cancer Res (2016) 76 (14_Supplement): 5241.

https://doi.org/10.1158/1538-7445.AM2016-5241

Published: 15 July 2016

View article titled, Abstract 5241: Nitric oxide-releasing naproxen prevents muscle invasive bladder cancer

Journal Articles

Abstract 2625: Simultaneous targeting of ODC and 5-LOX/COX block the tobacco carcinogen-induced lung adenoma progression to adenocarcinoma in A/J mice

Gaurav Kumar, Jagan Mohan R. Patolla, Venkateshwar Madka, Altaf Mohammed, Li Qian, Yuting Zhang, Laura Biddick, Anil Singh, Allison Gillaspy, Stanley Lightfoot, Levy Kopelovich, Vernon E. Steele, Chinthalapally V. Rao

Cancer Res (2016) 76 (14_Supplement): 2625.

https://doi.org/10.1158/1538-7445.AM2016-2625

Published: 15 July 2016

View article titled, Abstract 2625: Simultaneous targeting of ODC and 5-LOX/COX block the tobacco carcinogen-induced lung adenoma progression to adenocarcinoma in A/J mice

Journal Articles

Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53

Shengliang Zhang, Lanlan Zhou, Bo Hong, A. Pieter J. van den Heuvel, Varun V. Prabhu, Noel A. Warfel, Christina Leah B. Kline, David T. Dicker, Levy Kopelovich, Wafik S. El-Deiry

Cancer Res (2015) 75 (18): 3842–3852.

https://doi.org/10.1158/0008-5472.CAN-13-1079

Published: 14 September 2015

View article titled, Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53

Includes: Supplementary data

Journal Articles

Abstract 4653: Modulation of mTOR and p53 signaling using rapamycin plus CP-31398 inhibits growth and progression of urothelial carcinoma in-vivo

Venkateshwar Madka, Altaf Mohammed, Qian Li, Yuting Zhang, Laura Biddick, Jagan M.R. Patlolla, Stanley Lightfoot, Xue-Ru Wu, Vernon Steele, Levy Kopelovich, Chinthalapally V. Rao

Cancer Res (2015) 75 (15_Supplement): 4653.

https://doi.org/10.1158/1538-7445.AM2015-4653

Published: 01 August 2015

View article titled, Abstract 4653: Modulation of mTOR and p53 signaling using rapamycin plus CP-31398 inhibits growth and progression of urothelial carcinoma in-vivo

Journal Articles

Abstract 2815: Sulindac reversal of 15-PGDH mediated resistance to colon tumor chemoprevention with NSAIDs

Stephen P. Fink, Dawn M. Dawson, Yongyou Zhang, Adam Kresak, Earl G. Lawrence, Peiying Yang, Yanwen Chen, Jill S. Barnholtz-Sloan, Joseph E. Willis, Levy Kopelovich, Sanford D. Markowitz

Cancer Res (2015) 75 (15_Supplement): 2815.

https://doi.org/10.1158/1538-7445.AM2015-2815

Published: 01 August 2015

View article titled, Abstract 2815: Sulindac reversal of 15-PGDH mediated resistance to colon tumor chemoprevention with NSAIDs

Journal Articles

Abstract 1260: CP-31398 prevents the progression of oral squamous cell carcinomas from carcinogen-induced premalignant lesions

Lynn A. Vitale-Cross, Daniel Martin, Chinthalapally V. Rao, Levy Kopelovich, J. Silvio Gutkind

Cancer Res (2014) 74 (19_Supplement): 1260.

https://doi.org/10.1158/1538-7445.AM2014-1260

Published: 01 October 2014

View article titled, Abstract 1260: CP-31398 prevents the progression of oral squamous cell carcinomas from carcinogen-induced premalignant lesions

Journal Articles

Abstract 1244: Licofelone, a dual COX-LOX inhibitor prevents transitional cell carcinoma of urinary bladder in UPII-SV40T transgenic mice

Venkateshwar Madka, Altaf Mohammed, Qian Li, Yuting Zhang, Laura Biddick, Stanley Lightfoot, Xue-Re Wu, Levy Kopelovich, Vernon Steele, Chinthallapally V. Rao

Cancer Res (2014) 74 (19_Supplement): 1244.

https://doi.org/10.1158/1538-7445.AM2014-1244

Published: 01 October 2014

View article titled, Abstract 1244: Licofelone, a dual COX-LOX inhibitor prevents transitional cell carcinoma of urinary bladder in UPII-SV40T transgenic mice

Journal Articles

Abstract 2135: Chemoprevention of tobacco carcinogen-induced lung cancer by DFMO and Licofelone administered individually or in combination in female A/J mice

Jagan Mohan Reddy Patlolla, Levy Kopelovich, Li Qian, Laura Biddick, Yuting Zhang, Michael K. Sadeghi, Dhimant Desai, Shantu Amin, Stan Lightfoot, Vernon E. Steele, Chinthalapally V. Rao

Cancer Res (2014) 74 (19_Supplement): 2135.

https://doi.org/10.1158/1538-7445.AM2014-2135

Published: 01 October 2014

View article titled, Abstract 2135: Chemoprevention of tobacco carcinogen-induced lung cancer by DFMO and Licofelone administered individually or in combination in female A/J mice

Journal Articles

Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53

Bo Hong, Varun V. Prabhu, Shengliang Zhang, A. Pieter J. van den Heuvel, David T. Dicker, Levy Kopelovich, Wafik S. El-Deiry

Cancer Res (2014) 74 (4): 1153–1165.

https://doi.org/10.1158/0008-5472.CAN-13-0955

Published: 16 February 2014

View article titled, Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53

Includes: Supplementary data

Journal Articles

PPARδ Induces Estrogen Receptor-Positive Mammary Neoplasia through an Inflammatory and Metabolic Phenotype Linked to mTOR Activation

Hongyan Yuan, Jin Lu, Junfeng Xiao, Geeta Upadhyay, Rachel Umans, Bhaskar Kallakury, Yuhzi Yin, Michael E. Fant, Levy Kopelovich, Robert I. Glazer

Cancer Res (2013) 73 (14): 4349–4361.

https://doi.org/10.1158/0008-5472.CAN-13-0322

Published: 15 July 2013

View article titled, PPARδ Induces Estrogen Receptor-Positive Mammary Neoplasia through an Inflammatory and Metabolic Phenotype Linked to mTOR Activation

Includes: Supplementary data

Journal Articles

Abstract 2188: A screen to identify novel p53 family member activity-restoring compounds with a focus on p73.

Antonius P. van den Heuvel, Wenge Wang, Levy Kopelovich, Wafik S. El-Deiry

Cancer Res (2013) 73 (8_Supplement): 2188.

https://doi.org/10.1158/1538-7445.AM2013-2188

Published: 15 April 2013

View article titled, Abstract 2188: A screen to identify novel p53 family member activity-restoring compounds with a focus on p73.

Journal Articles

Abstract 197: Reduction in lobular but not ductal hyperplasia by the PGR inhibitor ORG33628 in a CYP19A1 overexpressing mouse model of breast cancer risk.

Sarah A. Dabydeen, Weisheng Wang, Edgar S. Diaz-Cruz, Levy Kopelovich, Robert I. Glazer, Priscilla A. Furth

Cancer Res (2013) 73 (8_Supplement): 197.

https://doi.org/10.1158/1538-7445.AM2013-197

Published: 15 April 2013

View article titled, Abstract 197: Reduction in lobular but not ductal hyperplasia by the PGR inhibitor ORG33628 in a CYP19A1 overexpressing mouse model of breast cancer risk.

Journal Articles

Abstract 2171: A new small molecule compound restoring p53 pathway induces cell death via active p73 and degradation of mutant p53 in colorectal cancer cells.

Shengliang Zhang, Lanlan Zhou, Bo Hong, Noel Warfel, Antonius Van den heuvel, David Dicker, Levy Kopelovich, Wafik El-Deiry

Cancer Res (2013) 73 (8_Supplement): 2171.

https://doi.org/10.1158/1538-7445.AM2013-2171

Published: 15 April 2013

View article titled, Abstract 2171: A new small molecule compound restoring p53 pathway induces cell death via active p73 and degradation of mutant p53 in colorectal cancer cells.

Journal Articles

Abstract 3690: p53 stabilizing agent CP-31398 prevents urinary bladder tumor growth and invasion in transgenic UPII-SV40T mice.

Venkateshwar Madka, Yuting Zhang, Qian Li, Altaf Mohammed, Stan Lightfoot, Wu Re Xue, Levy Kopelovich, Chinthalapally V. Rao

Cancer Res (2013) 73 (8_Supplement): 3690.

https://doi.org/10.1158/1538-7445.AM2013-3690

Published: 15 April 2013

View article titled, Abstract 3690: p53 stabilizing agent CP-31398 prevents urinary bladder tumor growth and invasion in transgenic UPII-SV40T mice.

Journal Articles

Abstract 1385: PPARδ promotes mammary tumorigenesis through mTOR activation.

Robert I. Glazer, Hongyan Yuan, Geeta Upadhyay, Yuzhi Yin, Levy Kopelovich

Cancer Res (2013) 73 (8_Supplement): 1385.

https://doi.org/10.1158/1538-7445.AM2013-1385

Published: 15 April 2013

View article titled, Abstract 1385: PPARδ promotes mammary tumorigenesis through mTOR activation.

Journal Articles

Abstract LB-182: Licofelone inhibits NNK-induced lung adenocarcinoma formation in A/J mice by suppressing COX/LOX and inhibits human lung cancer cell growth by p21 up-regulation.

Jagan Mohan Reddy Patlolla, Levy Kopelovich, Li Qian, Laura Biddick, Yuting Zhang, Dhimant Desai, Shantu Amin, Stan Lightfoot, Chinthalapally V. Rao

Cancer Res (2013) 73 (8_Supplement): LB-182.

https://doi.org/10.1158/1538-7445.AM2013-LB-182

Published: 15 April 2013

View article titled, Abstract LB-182: Licofelone inhibits NNK-induced lung adenocarcinoma formation in A/J mice by suppressing COX/LOX and inhibits human lung cancer cell growth by p21 up-regulation.

Journal Articles

Abstract LB-53: Prodigiosin rescues mutant p53 signaling and antitumor effects via p73 upregulation and disruption of mutant p53:p73 interaction.

Bo Hong, Antonius Van Den Heuvel, Levy Kopelovich, Wafik S. El-Deiry

Cancer Res (2013) 73 (8_Supplement): LB-53.

https://doi.org/10.1158/1538-7445.AM2013-LB-53

Published: 15 April 2013

View article titled, Abstract LB-53: Prodigiosin rescues mutant p53 signaling and antitumor effects via p73 upregulation and disruption of mutant p53:p73 interaction.

Journal Articles

Abstract 2580: Induction of estrogen receptor alpha by GW9662 sensitizes mammary glands to tamoxifen treatment in organ culture

Rajendra G. Mehta, Xinjian Peng, Sarbani Roy, Rajeshwari Mehta, Levy Kopelovich

Cancer Res (2012) 72 (8_Supplement): 2580.

https://doi.org/10.1158/1538-7445.AM2012-2580

Published: 15 April 2012

View article titled, Abstract 2580: Induction of estrogen receptor alpha by GW9662 sensitizes mammary glands to tamoxifen treatment in organ culture

Journal Articles

Abstract 2628: Genome-wide sequencing identifies ATM as a pancreatic cancer susceptibility gene

Cancer Res (2012) 72 (8_Supplement): 2628.

https://doi.org/10.1158/1538-7445.AM2012-2628

Published: 15 April 2012

View article titled, Abstract 2628: Genome-wide sequencing identifies <em>ATM</em> as a pancreatic cancer susceptibility gene

NARROW

Abstract CT111: Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa

Abstract 5241: Nitric oxide-releasing naproxen prevents muscle invasive bladder cancer

Abstract 2625: Simultaneous targeting of ODC and 5-LOX/COX block the tobacco carcinogen-induced lung adenoma progression to adenocarcinoma in A/J mice

Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53

Abstract 4653: Modulation of mTOR and p53 signaling using rapamycin plus CP-31398 inhibits growth and progression of urothelial carcinoma in-vivo

Abstract 2815: Sulindac reversal of 15-PGDH mediated resistance to colon tumor chemoprevention with NSAIDs

Abstract 1260: CP-31398 prevents the progression of oral squamous cell carcinomas from carcinogen-induced premalignant lesions

Abstract 1244: Licofelone, a dual COX-LOX inhibitor prevents transitional cell carcinoma of urinary bladder in UPII-SV40T transgenic mice

Abstract 2135: Chemoprevention of tobacco carcinogen-induced lung cancer by DFMO and Licofelone administered individually or in combination in female A/J mice

Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53

PPARδ Induces Estrogen Receptor-Positive Mammary Neoplasia through an Inflammatory and Metabolic Phenotype Linked to mTOR Activation

Abstract 2188: A screen to identify novel p53 family member activity-restoring compounds with a focus on p73.

Abstract 197: Reduction in lobular but not ductal hyperplasia by the PGR inhibitor ORG33628 in a CYP19A1 overexpressing mouse model of breast cancer risk.

Abstract 2171: A new small molecule compound restoring p53 pathway induces cell death via active p73 and degradation of mutant p53 in colorectal cancer cells.

Abstract 3690: p53 stabilizing agent CP-31398 prevents urinary bladder tumor growth and invasion in transgenic UPII-SV40T mice.

Abstract 1385: PPARδ promotes mammary tumorigenesis through mTOR activation.

Abstract LB-182: Licofelone inhibits NNK-induced lung adenocarcinoma formation in A/J mice by suppressing COX/LOX and inhibits human lung cancer cell growth by p21 up-regulation.

Abstract LB-53: Prodigiosin rescues mutant p53 signaling and antitumor effects via p73 upregulation and disruption of mutant p53:p73 interaction.

Abstract 2580: Induction of estrogen receptor alpha by GW9662 sensitizes mammary glands to tamoxifen treatment in organ culture

Abstract 2628: Genome-wide sequencing identifies ATM as a pancreatic cancer susceptibility gene

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