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Leslie L. Sharp
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Journal Articles

Abstract 5618: Multi-armed myxoma virus has therapeutic potential for treatment of multiple myeloma

Ana L. de Matos, Rachel Dutcher, Lina S. Franco, Lino E. Torres-Dominguez, Heather Hrach, Mario Abrantes, Wazir Abdullahi, Zachary Tacner, Dillon McCrite, Nicole Grigiatis, Jack St. Peter, Leslie L. Sharp
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5618.
https://doi.org/10.1158/1538-7445.AM2022-5618
Published: 15 June 2022
View article titled, Abstract 5618: Multi-armed myxoma virus has therapeutic potential for treatment of multiple myeloma
Journal Articles

Abstract 1919: Prediction of systemic cytokine exposure in human after IV administration of oncolytic myxoma virus, using quantitative systems pharmacology modeling

A. Katharina Wilkins, Lina S. Franco, Diana H. Marcantonio, Karyn L. Sutton, Joshua F. Apgar, John M. Burke, Grant McFadden, Fei Hua, Leslie L. Sharp
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1919.
https://doi.org/10.1158/1538-7445.AM2021-1919
Published: 01 July 2021
View article titled, Abstract 1919: Prediction of systemic cytokine exposure in human after IV administration of oncolytic myxoma virus, using quantitative systems pharmacology modeling
Journal Articles

Abstract 1921: Armed oncolytic myxoma virus demonstrates efficacy in syngeneic tumor models alone and in combination with immune checkpoint inhibitors

Lina S. Franco, Joseph Mamola, Wazir Abdullahi, Ana de Matos, Mario Abrantes, Benjamin S. Walker, Zachary Tacner, Nicole Grigaitis, Cassandra Kien, Grant McFadden, Leslie L. Sharp
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1921.
https://doi.org/10.1158/1538-7445.AM2021-1921
Published: 01 July 2021
View article titled, Abstract 1921: Armed oncolytic myxoma virus demonstrates efficacy in syngeneic tumor models alone and in combination with immune checkpoint inhibitors
Journal Articles

Abstract 1920: Armed oncolytic myxoma virus demonstrates transgene production, function, and therapeutic activity xenograft models

Lina S. Franco, Mario Abrantes, Wazir Abdullahi, Ana L. de Matos, Benjamin S. Walker, Zachary Tacner, Cassandra Kien, Nicole Grigaitis, Grant McFadden, Steven J. Potts, Leslie L. Sharp
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1920.
https://doi.org/10.1158/1538-7445.AM2021-1920
Published: 01 July 2021
View article titled, Abstract 1920: Armed oncolytic myxoma virus demonstrates transgene production, function, and therapeutic activity xenograft models
Journal Articles

Abstract 827: Anti-tumor efficacy of BA3011, a novel Conditionally Active Biologic (CAB) anti-AXL-ADC

Leslie L. Sharp, Cathy Chang, Gerhard Frey, Jing Wang, Haizhen Liu, Charles Xing, Safak Yalcin, Marlena Walls, Yong Ben, William J. Boyle, Jay M. Short
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 827.
https://doi.org/10.1158/1538-7445.AM2018-827
Published: 01 July 2018
View article titled, Abstract 827: Anti-tumor efficacy of BA3011, a novel Conditionally Active Biologic (CAB) anti-AXL-ADC
Journal Articles

Abstract 833: Anti-tumor efficacy of BA3021, a novel Conditionally Active Biologic (CAB) anti-ROR2 ADC

Leslie L. Sharp, Cathy Chang, Gerhard Frey, Jing Wang, Haizhen Liu, Charles Xing, Safak Yalcin, Marlena Walls, Yong Ben, William J. Boyle, Jay M. Short
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 833.
https://doi.org/10.1158/1538-7445.AM2018-833
Published: 01 July 2018
View article titled, Abstract 833: Anti-tumor efficacy of BA3021, a novel Conditionally Active Biologic (CAB) anti-ROR2 ADC
Journal Articles

Abstract 4555: Potent Conditionally Active Biologic (CAB) PD-1 antibodies to reduce systemic toxicities associated with single agent and combination therapies

Cathy Chang, Gerhard Frey, Leslie L. Sharp, Haizhen Liu, Jing Wang, Charles Xing, Safak Yalcin, Yong Ben, William J. Boyle, Jay M. Short
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4555.
https://doi.org/10.1158/1538-7445.AM2018-4555
Published: 01 July 2018
View article titled, Abstract 4555: Potent Conditionally Active Biologic (CAB) PD-1 antibodies to reduce systemic toxicities associated with single agent and combination therapies
Journal Articles

Abstract 3836: Novel conditionally active biologic anti-Axl antibody-drug conjugate demonstrates anti-tumor efficacy and improved safety profile

Cathy Chang, Gerhard Frey, William J. Boyle, Leslie L. Sharp, Jay M. Short
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3836.
https://doi.org/10.1158/1538-7445.AM2016-3836
Published: 15 July 2016
View article titled, Abstract 3836: Novel conditionally active biologic anti-Axl antibody-drug conjugate demonstrates anti-tumor efficacy and improved safety profile
Journal Articles

Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies

Inge Verbrugge, Jim Hagekyriakou, Leslie L. Sharp, Mara Galli, Alison West, Nicole M. McLaughlin, Hélène Duret, Hideo Yagita, Ricky W. Johnstone, Mark J. Smyth, Nicole M. Haynes
Journal: Cancer Research
Cancer Res (2012) 72 (13): 3163–3174.
https://doi.org/10.1158/0008-5472.CAN-12-0210
Published: 01 July 2012
View article titled, Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
Open the PDF for Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies in another window
Includes: Supplementary data
Journal Articles

Abstract 4384: Targeting of 4-1BB by monoclonal antibody, PF-05082566, enhances T cell function and promotes antitumor activity

Timothy S. Fisher, Cris Kamperschroer, Theodore Oliphant, Victoria A. Love, Paul D. Lira, Regis Doyonnas, Simon Bergqvist, Sangita Baxi, Allison Rohner, Amy C. Shen, Chunli Huang, Sharon Sokolowski, Leslie L. Sharp
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4384.
https://doi.org/10.1158/1538-7445.AM2012-4384
Published: 15 April 2012
View article titled, Abstract 4384: Targeting of 4-1BB by monoclonal antibody, PF-05082566, enhances T cell function and promotes antitumor activity