1-20 of 39
Leslie Cope
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract CT016: Immunomodulation of the tumor microenvironment of pancreatic ductal adenocarcinoma with histone deacetylase inhibition: Results of a phase 2 clinical trial of entinostat in combination with nivolumab

Marina Baretti, Ludmila Danilova, Jennifer N. Durham, Courtney B. Betts, Leslie Cope, Dimitrios N. Sidiropoulos, Joseph A. Tandurella, Soren Charmsaz, Nicole Gross, Alexei Hernandez, Won J. HO, Chris Thoburn, Rosalind Walker, James Leatherman Leatherman, Sarah Mitchell, Brian Christmas, Daria A. Gaykalova, Srinivasan Yegnasubramanian, Elana J. Fertig, Lisa M. Coussens, Mark Yarchoan, Elizabeth Jaffee, Nilofer S. Azad
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT016.
https://doi.org/10.1158/1538-7445.AM2024-CT016
Published: 05 April 2024
View article titled, Abstract CT016: Immunomodulation of the tumor microenvironment of pancreatic ductal adenocarcinoma with histone deacetylase inhibition: Results of a phase 2 clinical trial of entinostat in combination with nivolumab
Journal Articles

Abstract 1463: Characterizing inflammation-induced epigenetic and transcriptomic alterations driving NSCLC using lung organoid models

Na Wang, Kara Lombardo, Raksha Padaki, Ray-Whay Chiu Yen, Malcolm V. Brock, Leslie Cope, Hariharan Easwaran, Stephen B. Baylin, Michelle Vaz
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1463.
https://doi.org/10.1158/1538-7445.AM2024-1463
Published: 22 March 2024
View article titled, Abstract 1463: Characterizing inflammation-induced epigenetic and transcriptomic alterations driving NSCLC using lung organoid models
Journal Articles

Abstract 2631: HMGA1 chromatin regulators drive immune evasion in myeloproliferative neoplasms by repressing gene networks involved in antigen presentation

Linda M. S. Resar, Joseph Kim, Audrey-Ann Supreme, Bailey West, Mariah Antopia, Hyungsung Woo, Karen Reddy, Jung-Hyun Kim, Leslie Cope, Jerry Spivak, Alison Moliterno
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2631.
https://doi.org/10.1158/1538-7445.AM2024-2631
Published: 22 March 2024
View article titled, Abstract 2631: HMGA1 chromatin regulators drive immune evasion in myeloproliferative neoplasms by repressing gene networks involved in antigen presentation
Journal Articles

Abstract 2260: Characterizing tumor stromal evolution after neoadjuvant anti-PD-1 therapy in Merkel cell carcinoma

Joel C. Sunshine, Tracee L. McMiller, Alyza Skaist, Yan Zhang, Alan Berger, Kornel Schuebel, Jennifer Meyers, Julie S. Deutsch, Aleksandra Ogurtsova, Elizabeth L. Engle, Leslie Cope, Janis M. Taube, Suzanne L. Topalian
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2260.
https://doi.org/10.1158/1538-7445.AM2023-2260
Published: 04 April 2023
View article titled, Abstract 2260: Characterizing tumor stromal evolution after neoadjuvant anti-PD-1 therapy in Merkel cell carcinoma
Journal Articles

Abstract 3126: Multimodal genome-wide survey of progressing and non-progressing DCIS

Marija Debeljak, Soonweng Cho, Bradley Downs, Michael Considine, Brittany Avin-McKelvey, Yongchun Wang, William Grizzle, Katherine Hoadley, Charles Lynch, Brenda Hernandez, Paul van Diest, Wendy Cozen, Ann Hamilton, Debra Hawes, Edward Gabrielson, Ashley Cimino-Mathews, Liliana Florea, Leslie Cope, Christopher B. Umbricht
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3126.
https://doi.org/10.1158/1538-7445.AM2023-3126
Published: 04 April 2023
View article titled, Abstract 3126: Multimodal genome-wide survey of progressing and non-progressing DCIS
Journal Articles

Abstract 1969: DNA methylation and mutation spectrum among pediatric acute lymphoblastic leukemia patients by Hispanic/Latinx ethnicity

Alexander Miller, Michael Considine, Leslie Cope, Ernest K. Amankwah
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1969.
https://doi.org/10.1158/1538-7445.AM2023-1969
Published: 04 April 2023
View article titled, Abstract 1969: DNA methylation and mutation spectrum among pediatric acute lymphoblastic leukemia patients by Hispanic/Latinx ethnicity
Journal Articles

Abstract P4-02-09: Evaluation of the Automated Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC-005 Prospective Trial

Kala Visvanathan, Leslie Cope, Mary Jo Fackler, Michael Considine, Lisa Carey, Andres Forero-Torres, James N. Ingle, Nancy U. Lin, Rita Nanda, Anna Maria Storniolo, Suzana Tulac, Natalie C. Wu, Sudhakar Marla, Neesha R. Venkatesan, Antonio C. Wolff, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-02-09.
https://doi.org/10.1158/1538-7445.SABCS22-P4-02-09
Published: 01 March 2023
View article titled, Abstract P4-02-09: Evaluation of the Automated Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC-005 Prospective Trial
Journal Articles

Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis

Yeh Wang, Peng Huang, Brant G. Wang, Tricia Murdock, Leslie Cope, Fang-Chi Hsu, Tian-Li Wang, Ie-Ming Shih
Journal: Cancer Research
Cancer Res (2022) 82 (24): 4528–4541.
https://doi.org/10.1158/0008-5472.CAN-22-1620
Published: 16 December 2022
View article titled, Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis
Open the PDF for Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 2414: HMGA1 induces FGF19 to drive tumor progression and recruit cancer associated fibroblasts in pancreatic adenocarcinoma

Lionel Chia, Shuai Shuai, Jung-Hyun Kim, Woo Jung Sung, Ruitao Zhang, Tait Huso, Leslie Cope, Karen Reddy, Linda M. Resar
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2414.
https://doi.org/10.1158/1538-7445.AM2021-2414
Published: 01 July 2021
View article titled, Abstract 2414: HMGA1 induces <em>FGF19</em> to drive tumor progression and recruit cancer associated fibroblasts in pancreatic adenocarcinoma
Journal Articles

Abstract 2666: HMGA1: An epigenetic switch required for MPN progression by inducing GATA-2 and cell cycle progression through enhancer rewiring

Liping Li, Jung-Hyun Kim, Wenyan Lu, Donna Marie Williams, Lingling Xian, Joseph Kim, Ophelia Rogers, Raajit K. Rampal, Richard P. Koche, Leslie Cope, Karen Reddy, Daniel R. Matson, Joe Zhao, Jerry L. Spivak, Alison R. Moliterno, Linda Resar
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2666.
https://doi.org/10.1158/1538-7445.AM2021-2666
Published: 01 July 2021
View article titled, Abstract 2666: HMGA1: An epigenetic switch required for MPN progression by inducing <em>GATA-2</em> and cell cycle progression through enhancer rewiring
Journal Articles

Abstract OT-13-08: A remote-directed “virtual” clinical trial in metastatic breast cancer to determine feasibility of evaluating patient response to immunotherapy using spliceosome mutational markers (SF3B1): The PRISMM trial (NCT04447651)

Natasha Hunter, Jeffrey Wang, Leslie Cope, Christine Hodgdon, Vered Stearns, Elizabeth Jaffee, Ben Park, Cesar A Santa-Maria
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): OT-13-08.
https://doi.org/10.1158/1538-7445.SABCS20-OT-13-08
Published: 15 February 2021
View article titled, Abstract OT-13-08: A remote-directed “virtual” clinical trial in metastatic breast cancer to determine feasibility of evaluating patient response to immunotherapy using spliceosome mutational markers (SF3B1): The PRISMM trial (NCT04447651)
Journal Articles

Abstract 297: HMGA1 induces FGF-19 to foster tumor-stromal cell crosstalk and drive tumor progression in pancreatic ductal adenocarcinoma

Lionel Chia, Shuai Shuai, Lingling Xian, Jung-Hyun Kim, Ruitao Zhang, Tait Huso, David Huso, Leslie Cope, Karen Reddy, Linda Resar
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 297.
https://doi.org/10.1158/1538-7445.AM2020-297
Published: 15 August 2020
View article titled, Abstract 297: HMGA1 induces FGF-19 to foster tumor-stromal cell crosstalk and drive tumor progression in pancreatic ductal adenocarcinoma
Journal Articles

Abstract CT043: A multicenter randomized phase 2 trial of atezolizumab as monotherapy or in combination with cobimetinib in biliary tract cancers (BTCs): A NCI Experimental Therapeutics Clinical Trials Network (ETCTN) study

Mark Yarchoan, Leslie Cope, Robert A. Anders, Anne Noonan, Laura W. Goff, Lipika Goyal, Jill Lacy, Daneng Li, Anuj Patel, Aiwu R. He, Ghassan Abou-Alfa, Kristen Spencer, Edward Kim, Stephanie Xavier, Amanda Ruggieri, S. Lindsey Davis, Autumn McRee, Paul Kunk, Qingfeng Zhu, Andrea Wang-Gillam, Andrew Poklepovic, Helen Chen, Elad Sharon, Gregory B. Lesinski, Nilo Azad
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT043.
https://doi.org/10.1158/1538-7445.AM2020-CT043
Published: 15 August 2020
View article titled, Abstract CT043: A multicenter randomized phase 2 trial of atezolizumab as monotherapy or in combination with cobimetinib in biliary tract cancers (BTCs): A NCI Experimental Therapeutics Clinical Trials Network (ETCTN) study
Journal Articles

Abstract P6-10-05: TBCRC 040: Pathologic response evaluation and detection in circulating tumor DNA (PREDICT DNA): Initial results piloting a tissue-biopsy independent method of identifying and monitoring tumor-specific mutations in early stage breast cancer

Natasha Hunter, Heather Parsons, Alexander Sherry, Daniel Shinn, Dong Ho Shin, Alex Cole, Giovanni Cragnotti, Taylor Groginski, Margaret Leathers, Andrea L Richardson, Pedram Argani, Antonio Wolff, Leslie Cope, Dan Edelstein, Frank Holtrup, Hilary Sloane, Bapsi Chakravarthy, Vered Stearns, Ben H Park
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-10-05.
https://doi.org/10.1158/1538-7445.SABCS19-P6-10-05
Published: 15 February 2020
View article titled, Abstract P6-10-05: TBCRC 040: Pathologic response evaluation and detection in circulating tumor DNA (PREDICT DNA): Initial results piloting a tissue-biopsy independent method of identifying and monitoring tumor-specific mutations in early stage breast cancer
Journal Articles

Abstract P4-02-06: Automated molecular diagnosis of suspicious axillary lymph nodes in breast cancer patients

Juanjuan Li, Bradley Downs, Leslie Cope, Xiuyun Zhang, Chuan-gui Song, Kejing Zhang, Yong Han, Mary Jo Fackler, Edwin Lai, Suzana Tulac, Neesha Venkatesan, Timothy Guzman, Chuang Chen, Jingping Yuan, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-02-06.
https://doi.org/10.1158/1538-7445.SABCS19-P4-02-06
Published: 15 February 2020
View article titled, Abstract P4-02-06: Automated molecular diagnosis of suspicious axillary lymph nodes in breast cancer patients
Journal Articles

Abstract 4041: Coupling neoantigen specific T cell clonotypes and their molecular phenotypes at the single cell level in resectable anti-PD-1 treated NSCLC

Justina X. Caushi, Zhicheng Ji, Jiajia Zhang, Margueritta El Asmar, Valsamo Anagnostou, Tricia R. Cottrell, Hok Yee Chan, Haidan Guo, Taha Merghoub, Jedd D. Wolchok, Jarushka Naidoo, Kristen A. Marrone, Jamie E. Chaft, Matthew D. Hellmann, Edward Gabrielson, Janis M. Taube, Julie R. Brahmer, Victor E. Velculescu, Ni Zhao, Ludmila Danilova, Leslie Cope, Patrick M. Forde, Drew M. Pardoll, Hongkai Ji, Srinivasan Yegnasubramanian, Kellie N. Smith
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4041.
https://doi.org/10.1158/1538-7445.AM2019-4041
Published: 01 July 2019
View article titled, Abstract 4041: Coupling neoantigen specific T cell clonotypes and their molecular phenotypes at the single cell level in resectable anti-PD-1 treated NSCLC
Journal Articles

Abstract 3399: Uncovering hidden sources of transcriptional dysregulation arising from inter- and intra-tumor heterogeneity

Bahman Afsari, Leslie Cope, Daria A. Gaykalova, Donald Geman, Sidharth Puram, Loyal A. Goff, Alexander Favorov, Elana Judith Fertig
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3399.
https://doi.org/10.1158/1538-7445.AM2019-3399
Published: 01 July 2019
View article titled, Abstract 3399: Uncovering hidden sources of transcriptional dysregulation arising from inter- and intra-tumor heterogeneity
Journal Articles

Abstract 2458: Spatial genomic heterogeneity of multifocal bladder cancer

Rachel Goldberg, Maria Del Carmen Rodriguez, Leslie Cope, Aline C. Tregnago, Evgeny Izumchenko, George J. Netto, David Sidransky, Mohammad O. Hoque
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2458.
https://doi.org/10.1158/1538-7445.AM2017-2458
Published: 01 July 2017
View article titled, Abstract 2458: Spatial genomic heterogeneity of multifocal bladder cancer
Journal Articles

Abstract 843: Spontaneous immortalization of human mammary epithelial cells from a woman with a germline STK11 mutation

David Euhus, Dawei Bu, Michael Considine, Leslie Cope
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 843.
https://doi.org/10.1158/1538-7445.AM2016-843
Published: 15 July 2016
View article titled, Abstract 843: Spontaneous immortalization of human mammary epithelial cells from a woman with a germline STK11 mutation
Journal Articles

Abstract 4231: Combination of epigenetic, differentiation and DNA damaging agents induce tumor cell death and stem cell depletion in breast cancer

Vanessa F. Merino, Nguyen Nguyen, Helen Sadik, Soonweng Cho, Leslie Cope, Xian C. Zhou, Zhe Zhang, Qian Chen, Duojia Pan, David L. Huso, Syed Ali, Christina Adams, Balázs Győrffy, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4231.
https://doi.org/10.1158/1538-7445.AM2015-4231
Published: 01 August 2015
View article titled, Abstract 4231: Combination of epigenetic, differentiation and DNA damaging agents induce tumor cell death and stem cell depletion in breast cancer