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Lenora Davis
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Journal Articles

Abstract 1065: Growth factor-mediated resistance to BRAF/MEK inhibitors in BRAF mutant melanoma

Bart Lutterbach, Chris Ware, Lenora Davis, Qing Zhang, Leigh Zawel, John Reilly, Bo-Sheng Pan
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1065.
https://doi.org/10.1158/1538-7445.AM2012-1065
Published: 15 April 2012
View article titled, Abstract 1065: Growth factor-mediated resistance to BRAF/MEK inhibitors in BRAF mutant melanoma
Journal Articles

Abstract 284: FGFR2 is required for growth and survival in a rare subset of FGFR2 amplified colorectal cancer

Anjili Mathur, Lenora Davis, Alessandra Di Bacco, Adi Gazdar, Bart Lutterbach
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 284.
https://doi.org/10.1158/1538-7445.AM10-284
Published: 15 April 2010
View article titled, Abstract 284: FGFR2 is required for growth and survival in a rare subset of <em>FGFR2</em> amplified colorectal cancer
Journal Articles

Abstract #3714: In vitro and in vivo antitumor activities of MK-2206, a new allosteric Akt inhibitor

Wei Lu, Debbie Defeo-Jones, Lenora Davis, Gaozhen Hang, Jennifer Tammam, Harold Hatch, Bart Lutterbach, Christopher Ware, Kathleen Haskell, Bob Drakas, Karen Leander, Karen Leander, Craig Cherrin, Aubrey Watkins, Kelly Hamilton, Philip Sanderson, Hans Huber, Pradip Majumder, Bo-Sheng Pan
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3714.
Published: 01 May 2009
View article titled, Abstract #3714: <em>In vitro</em> and <em>in vivo</em> antitumor activities of MK-2206, a new allosteric Akt inhibitor
Journal Articles

Abstract #1751: MK-8033, a selective c-Met / Ron inhibitor, suppresses tumor cell growth in vitro and in vivo

Elizabeth Harrington, Grace Chan, Melissa Chenard, William Dahlberg, Lenora Davis, Sujal Deshmukh, Christopher Dinsmore, Clayton Efferson, Gaozhen Hang, Harold Hatch, Nancy Kohl, Kaiko Kunii, Wei Lu, Bart Lutterbach, Pradip Majumder, Alan Northrup, Xianlu Qu, John Reilly, Craig Rosenstein, Alexander Szewczak, Jennifer Tammam, Christopher Ware, Qinwen Zheng, Bo-Sheng Pan
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1751.
Published: 01 May 2009
View article titled, Abstract #1751: MK-8033, a selective c-Met / Ron inhibitor, suppresses tumor cell growth <em>in vitro</em> and <em>in vivo</em>
Journal Articles

FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival

Bart Lutterbach, Kaiko Kunii, Lenora Davis, Harold Hatch, Julie Gorenstein, Masakazu Yashiro, Victoria Richon, Nancy Kohl, Cem Elbi, Wei Lu, Bo-Sheng Pan
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4874.
Published: 01 May 2008
View article titled, <em>FGFR2</em>-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival
Journal Articles

FGFR2-Amplified Gastric Cancer Cell Lines Require FGFR2 and Erbb3 Signaling for Growth and Survival

Kaiko Kunii, Lenora Davis, Julie Gorenstein, Harold Hatch, Masakazu Yashiro, Alessandra Di Bacco, Cem Elbi, Bart Lutterbach
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2340–2348.
https://doi.org/10.1158/0008-5472.CAN-07-5229
Published: 01 April 2008
View article titled, <em>FGFR2</em>-Amplified Gastric Cancer Cell Lines Require FGFR2 and Erbb3 Signaling for Growth and Survival
Open the PDF for <em>FGFR2</em>-Amplified Gastric Cancer Cell Lines Require FGFR2 and Erbb3 Signaling for Growth and Survival in another window
Includes: Supplementary data
Journal Articles

In vitro and in vivo anti-tumor activities of a novel c-Met kinase inhibitor

Bo-Sheng Pan, Melissa Chenard, Lenora Davis, Sujal Deshmukh, Jackson Gibbs, Gaozhen Hang, Harold Hatch, James Jewell, Jason Katz, Kaiko Kunii, Wei Lu, Bart Lutterbach, Xianlu Qu, John Reilly, Alexander Szewczak, Qinwen Zeng, Nancy Kohl, Christopher Dinsmore
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2368.
Published: 01 May 2007
View article titled, In vitro and in vivo anti-tumor activities of a novel c-Met kinase inhibitor
Journal Articles

Pharmacodynamic evaluation of an indolyl quinolinone KDR/Flt-3 kinase inhibitor in normal healthy volunteers.

Stephen Beck, Aimee Dallob, Lenora Davis, Mary Flynn, Wesley Tanaka, Yih Lee, Yang Xu, Chau Thach, Kathryn Mazina, Inge De Lepeleire, Kristien Van Dyck, Anne Johnson, Qinwen Zeng, Bo-Sheng Pan, Kenneth Thomas, Jackson Gibbs, Howard Greenberg, Pierre Zachee, Steven Ramael, Keith Gottesdiener, Paul Deutsch, Nancy Kohl, Marian Iwamoto, Laura Sepp-Lorenzino
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 490.
Published: 01 April 2004
View article titled, Pharmacodynamic evaluation of an indolyl quinolinone KDR/Flt-3 kinase inhibitor in normal healthy volunteers.
Journal Articles

Anti-tumor and anti-metastatic effects of novel oral bioavailable KDR inhibitors in rat tumor models

Bin Shi, Susan Hill, Laura Schina, Rosemary McFall, Xianzhi Mao, Noelle P. Dahl, Cindy Spencer Bauer, Sandra Veggian, Ryan Desautels, Brad Smith, Jeannine Manzella, Jim Destefano, Totoe Kuffuor, Alan Savitz, Patricia Rebbeck, Lenora Davis, Jennifer Shipman, Yi Yang, James Hardwick, Seth Clark, Varaporn Treemaneekarn, Kenneth Thomas, Jackson Gibbs, Nancy Kohl, Laura Sepp-Lorenzino
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1053.
Published: 01 April 2004
View article titled, Anti-tumor and anti-metastatic effects of novel oral bioavailable KDR inhibitors in rat tumor models
Journal Articles

Novel Flt-3/KDR inhibitor is effective against activated Flt-3 and is cytotoxic against Flt-3-driven leukemias in vitro and in vivo

Stephen Beck, Lenora Davis, Jennifer Shipman, Laura Schina, Bin Shi, Kathleen Coll, Keith Rickert, Anne Johnson, Qinwen Zeng, Bo-Sheng Pan, Kenneth Thomas, Aimee Dallob, Mary Flynn, Wesley Tanaka, Maricel Torrent, Yih Lee, Kathryn Mazina, Sarah Liou, Dale Schaar, Malgorzata Wojtowicz, Paul Deutsch, Marian Iwamoto, Jackson Gibbs, Nancy Kohl, Laura Sepp-Lorenzino
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1301.
Published: 01 April 2004
View article titled, Novel Flt-3/KDR inhibitor is effective against activated Flt-3 and is cytotoxic against Flt-3-driven leukemias <em>in vitro</em> and <em>in vivo</em>
Journal Articles

A Novel Orally Bioavailable Inhibitor of Kinase Insert Domain-Containing Receptor Induces Antiangiogenic Effects and Prevents Tumor Growth in Vivo

Laura Sepp-Lorenzino, Elaine Rands, Xianzhi Mao, Brett Connolly, Jennifer Shipman, Joanne Antanavage, Susan Hill, Lenora Davis, Stephen Beck, Keith Rickert, Kathleen Coll, Patrice Ciecko, Mark Fraley, William Hoffman, George Hartman, David Heimbrook, Jackson Gibbs, Nancy Kohl, Kenneth Thomas
Journal: Cancer Research
Cancer Res (2004) 64 (2): 751–756.
https://doi.org/10.1158/0008-5472.CAN-03-2871
Published: 26 January 2004
View article titled, A Novel Orally Bioavailable Inhibitor of Kinase Insert Domain-Containing Receptor Induces Antiangiogenic Effects and Prevents Tumor Growth <em>in Vivo</em>
Open the PDF for A Novel Orally Bioavailable Inhibitor of Kinase Insert Domain-Containing Receptor Induces Antiangiogenic Effects and Prevents Tumor Growth <em>in Vivo</em> in another window