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Journal Articles

The circMYBL2-Encoded p185 Protein Suppresses Colorectal Cancer Progression by Inhibiting Serine Biosynthesis

Ning Zhao, Yinghao Cao, Ruikang Tao, Xiuxian Zhu, Runze Li, Yajun Chen, Kaixiong Tao, Lei Li, Hengyu Chen, Xianxiong Ma
Journal: Cancer Research
Cancer Res (2024) 84 (13): 2155–2168.
https://doi.org/10.1158/0008-5472.CAN-23-2940
Published: 02 July 2024
View article titled, The circMYBL2-Encoded p185 Protein Suppresses Colorectal Cancer Progression by Inhibiting Serine Biosynthesis
Open the PDF for The circMYBL2-Encoded p185 Protein Suppresses Colorectal Cancer Progression by Inhibiting Serine Biosynthesis in another window
Includes: Supplementary data
Journal Articles

Abstract 5359: Targeted engineering mRNA 3′UTR length enhances immunotherapy response in prostate cancer

Furong Huang, Fuwen Yuan, Ya Cui, Lei Li, Kexin Li, Zhifen Cui, Jingyue Yan, Qiang Chen, Christopher Nicchitta, Wenbin Ye, Yuebao Zhang, William Hankey, Jeffrey Everitt, Ming Chen, Jiaoti Huang, Hongyan Wang, Xin Lu, Eric Wagner, Yizhou Dong, Wei Li, Qianben Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5359.
https://doi.org/10.1158/1538-7445.AM2024-5359
Published: 22 March 2024
View article titled, Abstract 5359: Targeted engineering mRNA 3′UTR length enhances immunotherapy response in prostate cancer
Journal Articles

Abstract 2395: Camrelizumab combined with apatinib and hepatic artery infusion chemotherapy (HAIC) as conversion therapy for patients with unresectable hepatocellular carcinoma(HCC): A single-arm exploratory clinical study

Lei Zhao, Bo Zhang, Xuetao Shi, Kai Cui, Jianxin Zhang, Jingtao Zhong, Zhongchao Li, Pengfei Sun, Chengsheng Zhang, Lei Li
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2395.
https://doi.org/10.1158/1538-7445.AM2024-2395
Published: 22 March 2024
View article titled, Abstract 2395: Camrelizumab combined with apatinib and hepatic artery infusion chemotherapy (HAIC) as conversion therapy for patients with unresectable hepatocellular carcinoma(HCC): A single-arm exploratory clinical study
Journal Articles

Abstract 5518: Use of antihypertensive drugs and the risk of cancer, findings of a population-based cohort study in Shanghai

Suna Wang, Li Xie, Ying Qian, Jie Wang, Guanglu Zhang, Lei Li, Weituo Zhang, Herbert Yu, Wensui Zhao, Biyun Qian
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5518.
https://doi.org/10.1158/1538-7445.AM2023-5518
Published: 04 April 2023
View article titled, Abstract 5518: Use of antihypertensive drugs and the risk of cancer, findings of a population-based cohort study in Shanghai
Journal Articles

Abstract 2233: Clinical validation of a methylation array-based diagnostic assay for improved classification of CNS tumors

Melissa Soucy, Nick Renzette, Xinming Zhuo, Prasanti Nuni, Kristi Herlth, Kevin Kelly, Gregory Omerza, Lei Li
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2233.
https://doi.org/10.1158/1538-7445.AM2023-2233
Published: 04 April 2023
View article titled, Abstract 2233: Clinical validation of a methylation array-based diagnostic assay for improved classification of CNS tumors
Journal Articles

Abstract 1723: Ferroptosis is a novel therapeutic target for RB1 deficient lethal prostate cancer

Mu-En Wang, Jiaqi Chen, Yi Lu, Jinjin Wy, Jianhong Ou, John Asara, Andrew Armstrong, Qianben Wang, Lei Li, Yuzhuo Wang, Jiaoti Huang, Ming Chen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1723.
https://doi.org/10.1158/1538-7445.AM2023-1723
Published: 04 April 2023
View article titled, Abstract 1723: Ferroptosis is a novel therapeutic target for RB1 deficient lethal prostate cancer
Journal Articles

Abstract 5091: The early change of serum interleukin 14α levels predicts the response to anti-PD-1 therapy in cancer

Bu Hai Wang, Cai Yue Chen, Xian Zhang, Yu Xiang Huang, Yi Chun Zeng, Lei Li, Mao Qi Wang, Jing Liang Guo, Qiu Xian Li, Long Shen, Juan J. Gu, Yi Chen Liang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5091.
https://doi.org/10.1158/1538-7445.AM2022-5091
Published: 15 June 2022
View article titled, Abstract 5091: The early change of serum interleukin 14α levels predicts the response to anti-PD-1 therapy in cancer
Journal Articles

Abstract 659: Evaluation of homologous recombination repair related gene mutation on survival and drug response in Chinese epithelial ovarian cancer patients

Lei Li, Kang Shao, Jianwei Zhang, Meng Liu, Kui Wu, Ming Wu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 659.
https://doi.org/10.1158/1538-7445.AM2021-659
Published: 01 July 2021
View article titled, Abstract 659: Evaluation of homologous recombination repair related gene mutation on survival and drug response in Chinese epithelial ovarian cancer patients
Journal Articles

Tumor Fibroblast–Derived FGF2 Regulates Expression of SPRY1 in Esophageal Tumor–Infiltrating T Cells and Plays a Role in T-cell Exhaustion

Qing-yun Chen, Yi-ni Li, Xin-yue Wang, Xu Zhang, Yi Hu, Lei Li, Da-qin Suo, Ke Ni, Zhuo Li, Jia-rong Zhan, Ting-ting Zeng, Ying-hui Zhu, Yan Li, Li-jia Ma, Xin-Yuan Guan
Journal: Cancer Research
Cancer Res (2020) 80 (24): 5583–5596.
https://doi.org/10.1158/0008-5472.CAN-20-1542
Published: 15 December 2020
View article titled, Tumor Fibroblast–Derived FGF2 Regulates Expression of SPRY1 in Esophageal Tumor–Infiltrating T Cells and Plays a Role in T-cell Exhaustion
Open the PDF for Tumor Fibroblast–Derived FGF2 Regulates Expression of SPRY1 in Esophageal Tumor–Infiltrating T Cells and Plays a Role in T-cell Exhaustion in another window
Includes: Supplementary data
Journal Articles

Abstract 3760: HH2710, a highly potent and selective erk1/2 inhibitor for the treatment of mapk mutant tumors

Lei Li, Min Huang, Leping Li, Yi Chen, Shuai Tang, Yi Su, Ruiping Dong, Jian Ding, Meiyu Geng
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3760.
https://doi.org/10.1158/1538-7445.AM2020-3760
Published: 15 August 2020
View article titled, Abstract 3760: HH2710, a highly potent and selective erk1/2 inhibitor for the treatment of mapk mutant tumors
Journal Articles

Abstract 295: Protein phosphatase, Mg2+/Mn2+ dependent 1G promotes proliferation via modulating phosphorylation of retinoblastoma protein and associates with poor outcome in hepatocellular carcinoma

Wen Hu, Xin Yuan Guan, Lei Li, Yinghui Zhu, Yan Li, Ting Ting Zeng, Yun Fei Wen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 295.
https://doi.org/10.1158/1538-7445.AM2020-295
Published: 15 August 2020
View article titled, Abstract 295: Protein phosphatase, Mg2+/Mn2+ dependent 1G promotes proliferation via modulating phosphorylation of retinoblastoma protein and associates with poor outcome in hepatocellular carcinoma
Journal Articles

Epstein–Barr Virus miRNA BART2-5p Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing RND3

Chen Jiang, Lei Li, Yan-Qun Xiang, Maria Li Lung, Tingting Zeng, Jiabin Lu, Sai Wah Tsao, Mu-Sheng Zeng, Jing-Ping Yun, Dora L.W. Kwong, Xin-Yuan Guan
Journal: Cancer Research
Cancer Res (2020) 80 (10): 1957–1969.
https://doi.org/10.1158/0008-5472.CAN-19-0334
Published: 15 May 2020
View article titled, Epstein–Barr Virus miRNA BART2-5p Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing RND3
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Includes: Supplementary data
Journal Articles

Editor's Note: PrLZ Protects Prostate Cancer Cells from Apoptosis Induced by Androgen Deprivation via the Activation of Stat3/Bcl-2 Pathway

Dong Zhang, Dalin He, Yan Xue, Ruoxiang Wang, Kaijie Wu, Hongjun Xie, Jin Zeng, Xinyang Wang, Haiyen E. Zhau, Leland W.K. Chung, Luke S. Chang, Lei Li
Journal: Cancer Research
Cancer Res (2019) 79 (23): 6054.
https://doi.org/10.1158/0008-5472.CAN-19-3162
Published: 02 December 2019
View article titled, Editor's Note: PrLZ Protects Prostate Cancer Cells from Apoptosis Induced by Androgen Deprivation via the Activation of Stat3/Bcl-2 Pathway
Open the PDF for Editor's Note: PrLZ Protects Prostate Cancer Cells from Apoptosis Induced by Androgen Deprivation via the Activation of Stat3/Bcl-2 Pathway in another window
Journal Articles

Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis

Xiang Yan, Xiaoshan Zhang, Li Wang, Ran Zhang, Xingxiang Pu, Shuhong Wu, Lei Li, Pan Tong, Jing Wang, Qing H. Meng, Vanessa B. Jensen, Luc Girard, John D. Minna, Jack A. Roth, Stephen G. Swisher, John V. Heymach, Bingliang Fang
Journal: Cancer Research
Cancer Res (2019) 79 (1): 125–132.
https://doi.org/10.1158/0008-5472.CAN-18-1938
Published: 02 January 2019
View article titled, Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis
Open the PDF for Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis in another window
Includes: Supplementary data
Journal Articles

PDSS2 Deficiency Induces Hepatocarcinogenesis by Decreasing Mitochondrial Respiration and Reprogramming Glucose Metabolism

Yan Li, Shuhai Lin, Lei Li, Zhi Tang, Yumin Hu, Xiaojiao Ban, Tingting Zeng, Ying Zhou, Yinghui Zhu, Song Gao, Wen Deng, Xiaoshi Zhang, Dan Xie, Yunfei Yuan, Peng Huang, Jinjun Li, Zongwei Cai, Xin-Yuan Guan
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (16): 4471–4481.
https://doi.org/10.1158/0008-5472.CAN-17-2172
Published: 14 August 2018
View article titled, <em>PDSS2</em> Deficiency Induces Hepatocarcinogenesis by Decreasing Mitochondrial Respiration and Reprogramming Glucose Metabolism
Open the PDF for <em>PDSS2</em> Deficiency Induces Hepatocarcinogenesis by Decreasing Mitochondrial Respiration and Reprogramming Glucose Metabolism in another window
Includes: Supplementary data
Journal Articles

Abstract 3437: Genomic alterations, mutation burden, and microsatellite instability status of Chinese intrahepatic cholangiocarcinoma

Jingyu Cao, Bo Jiang, Zimin Liu, Weibin Shu, Lei Li, Han Yang, Hua Li, Zhiyu Xiao, Maolin Yan, Jie Lin, Siqin Liu, Peng Zhang, Milind Javle, Ming Yao, Kai Wang, Haitao Zhao
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3437.
https://doi.org/10.1158/1538-7445.AM2018-3437
Published: 01 July 2018
View article titled, Abstract 3437: Genomic alterations, mutation burden, and microsatellite instability status of Chinese intrahepatic cholangiocarcinoma
Journal Articles

Abstract LB-377: Validation and application of a comprehensive next generation sequencing system for molecular characterization of solid tumor tissues

Mehdi Dehghani, Lei Li, Reynolds Brobey, Yue Wang, Kevin P. Rosenblatt, Robert J. Amato
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-377.
https://doi.org/10.1158/1538-7445.AM2018-LB-377
Published: 01 July 2018
View article titled, Abstract LB-377: Validation and application of a comprehensive next generation sequencing system for molecular characterization of solid tumor tissues
Journal Articles

Abstract 4607: G1/S transition-related gene mutations associated with survival of hepatocellular carcinoma patients

Bingyuan Zhang, Tianqiang Song, Pingzhou Yang, Songzhu Yang, Chao Guo, Lei Li, Shuang Ren, Maolin Yan, Weiyu Hu, Honglin Guo, Yongjian Zhang, Yanlin Li, Weifeng Wang, Kai Wang, Ming Yao
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4607.
https://doi.org/10.1158/1538-7445.AM2018-4607
Published: 01 July 2018
View article titled, Abstract 4607: G1/S transition-related gene mutations associated with survival of hepatocellular carcinoma patients
Journal Articles

STK33 Promotes Growth and Progression of Pancreatic Cancer as a Critical Downstream Mediator of HIF1α

Fanyang Kong, Xiangyu Kong, Yiqi Du, Ying Chen, Xuan Deng, Jianwei Zhu, Jiawei Du, Lei Li, Zhiliang Jia, Dacheng Xie, Zhaoshen Li, Keping Xie
Journal: Cancer Research
Cancer Res (2017) 77 (24): 6851–6862.
https://doi.org/10.1158/0008-5472.CAN-17-0067
Published: 14 December 2017
View article titled, STK33 Promotes Growth and Progression of Pancreatic Cancer as a Critical Downstream Mediator of HIF1α
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Includes: Supplementary data
Journal Articles

Huwe1 Sustains Normal Ovarian Epithelial Cell Transformation and Tumor Growth through the Histone H1.3-H19 Cascade

Dong Yang, Bin Sun, Xiaohong Zhang, Daomei Cheng, Xiaoping Yu, Lanzhen Yan, Lei Li, Sanqi An, Hua Jiang, Anna Lasorella, Antonio Iavarone, Shu Zhang, Fangdong Zou, Xudong Zhao
Journal: Cancer Research
Cancer Res (2017) 77 (18): 4773–4784.
https://doi.org/10.1158/0008-5472.CAN-16-2597
Published: 14 September 2017
View article titled, Huwe1 Sustains Normal Ovarian Epithelial Cell Transformation and Tumor Growth through the Histone H1.3-<em>H19</em> Cascade
Open the PDF for Huwe1 Sustains Normal Ovarian Epithelial Cell Transformation and Tumor Growth through the Histone H1.3-<em>H19</em> Cascade in another window
Includes: Supplementary data