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Lei Gao
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Journal Articles

Abstract LB168: Platelet RNA signature enables early and accurate detection of ovarian cancer: An intercontinental, biomarker identification study

Yue Gao, Chun-Jie Liu, Hua-Yi Li, Xiao-Ming Xiong, Sjors G.j.g. In ‘t Veld, Gui-Ling Li, Jia-Hao Liu, Guang-Yao Cai, Gui-Yan Xie, Shao-Qing Zeng, Yuan Wu, Jian-Hua Chi, Qiong Zhang, Xiao-Fei Jiao, Lin-Li Shi, Wan-Rong Lu, Wei-Guo Lv, Xing-Sheng Yang, Jurgen M.j. Piek, Cornelis D de Kroon, C.a.r. Lok, Anna Supernat, Sylwia Łapińska-Szumczyk, Anna Łojkowska, Anna J. Żaczek, Jacek Jassem, Bakhos A. Tannous, Nik Sol, Edward Post, Myron G. Best, Bei-Hua Kong, Xing Xie, Ding Ma, Thomas Wurdinger, An-Yuan Guo, Qing-Lei Gao
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB168.
https://doi.org/10.1158/1538-7445.AM2022-LB168
Published: 15 June 2022
View article titled, Abstract LB168: Platelet RNA signature enables early and accurate detection of ovarian cancer: An intercontinental, biomarker identification study
Journal Articles

Abstract 3617: METTL16 drives leukemogenesis and maintains leukemia stem cell self-renewal via reprogramming BCAA metabolism

Li Han, Lei Dong, Keith Leung, Zhicong Zhao, Yangchan Li, Ying Qing, Jianhuang Xue, Chao Shen, Zhenhua Chen, Lei Gao, Kitty Wang, Keren Zhou, Wei Li, Brandon Tan, Zheng Zhang, Xi Qin, Rui Su, Xiaolan Deng, Jianjun Chen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3617.
https://doi.org/10.1158/1538-7445.AM2022-3617
Published: 15 June 2022
View article titled, Abstract 3617: METTL16 drives leukemogenesis and maintains leukemia stem cell self-renewal via reprogramming BCAA metabolism
Journal Articles

Abstract 5436: HH2853 is a selective small molecular dual inhibitor of EZH1/2 with potent anti-tumor activities

Xu-Xing Chen, Qian-Qian Shen, Zhao Zhao, Yan-Fen Fang, Jun-Yu Yang, Ying-Lei Gao, Lei Liu, Yixiang Zhang, Yi Chen, Leping Li
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5436.
https://doi.org/10.1158/1538-7445.AM2022-5436
Published: 15 June 2022
View article titled, Abstract 5436: HH2853 is a selective small molecular dual inhibitor of EZH1/2 with potent anti-tumor activities
Journal Articles

Abstract 5247: Using real-world data to evaluate the performance of endocrine therapies in ER+/Her2- metastatic breast cancer patients

Tenghui Chen, Zhaojie Zhang, Lei Gao, Catherine Scholz, Antonio Gualberto, Lihua Yu, Kun Yu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5247.
https://doi.org/10.1158/1538-7445.AM2022-5247
Published: 15 June 2022
View article titled, Abstract 5247: Using real-world data to evaluate the performance of endocrine therapies in ER+/Her2- metastatic breast cancer patients
Journal Articles

Abstract P1-17-03: H3B-6545 in combination with palbociclib in women with metastatic estrogen receptor-positive (ER+), human epidermal growth factor receptor 2 (HER2)-negative breast cancer, phase 1b study

Stephen Johnston, Timothy J Pluard, Judy S Wang, Erika P Hamilton, Dejan Juric, Catherine R Scholz, Elizabeth Hnitecki, Sara Dar, Lei Gao, Lisa Cantagallo, Manav Korpal, Jianjun Alan Xiao, Lihua Yu, Tarek Sahmoud, Antonio Gualberto
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-17-03.
https://doi.org/10.1158/1538-7445.SABCS21-P1-17-03
Published: 15 February 2022
View article titled, Abstract P1-17-03: H3B-6545 in combination with palbociclib in women with metastatic estrogen receptor-positive (ER+), human epidermal growth factor receptor 2 (HER2)-negative breast cancer, phase 1b study
Journal Articles

Abstract P1-17-10: H3B-6545, a novel selective estrogen receptor covalent antagonist (SERCA), in estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer - A phase II study

Erika P Hamilton, Judy S Wang, Timothy Pluard, Aki Morikawa, E Claire Dees, Robert H Jones, Barbara Haley, Anne Armstrong, Adam L Cohen, Pamela Munster, Gail S Wright, Fadi Kayali, Lisa Cantagallo, Manav Korpal, Jenny Long, Jianjun Xiao, Benoit Destenaves, Lei Gao, Tarek Sahmoud, Antonio Gualberto, Dejan Juric
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-17-10.
https://doi.org/10.1158/1538-7445.SABCS21-P1-17-10
Published: 15 February 2022
View article titled, Abstract P1-17-10: H3B-6545, a novel selective estrogen receptor covalent antagonist (SERCA), in estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer - A phase II study
Journal Articles

Abstract LB147: Updates on clinical safety and efficacy result of GC027, the first-in-human, “Off-the-Shelf” CD7 CAR-T stand-alone therapy for adult patients with relapsed/refractory T-cell lymphoblastic leukemia (r/r T-ALL)

Shiqi Li, Lei Gao, Zhongtao Yuan, Kun Wu, Lin Liu, Le Luo, Yao Liu, Cheng Zhang, Yu Li, Duanpeng Wang, Zhimin Li, Xu Tan, Ruihao Huang, Dingsong Zhang, Youcheng Wang, Xinxin Wang, Jia Liu, Martina Sersch, Sanbin Wang, Xi Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB147.
https://doi.org/10.1158/1538-7445.AM2021-LB147
Published: 01 July 2021
View article titled, Abstract LB147: Updates on clinical safety and efficacy result of GC027, the first-in-human, “Off-the-Shelf” CD7 CAR-T stand-alone therapy for adult patients with relapsed/refractory T-cell lymphoblastic leukemia (r/r T-ALL)
Journal Articles

Abstract PS12-23: Development of H3B-6545, a first-in-class oral selective ER covalent antagonist (SERCA), for the treatment of ERaWT and ERaMUT breast cancer

Manav Korpal, Craig Furman, Xiaoling Puyang, Zhaojie Zhang, Zhenhua Wu, Deepti Banka, Subhasree Das, Benoit Destenaves, Lei Gao, Erika Hamilton, Ming-Hong Hao, Sean Irwin, Stephen Johnston, Jaya J Joshi, Dejan Juric, Amy Kim, Tuong-Vi Nguyen, Marc Pipas, Timothy Pluard, Victoria Rimkunas, Nathalie Rioux, Joanne Schindler, Peter Smith, Michael Thomas, John Wang, Judy S Wang, Markus Warmuth, Huilan Yao, Shihua Yao, Lihua Yu, Frédéric H Vaillancourt, David M Bolduc, Nicholas A Larsen, GuoZhu Zheng, Sudeep Prajapati, Tarek Sahmoud, Antonio Gualberto, Ping Zhu
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS12-23.
https://doi.org/10.1158/1538-7445.SABCS20-PS12-23
Published: 15 February 2021
View article titled, Abstract PS12-23: Development of H3B-6545, a first-in-class oral selective ER covalent antagonist (SERCA), for the treatment of ERa<sup>WT</sup> and ERa<sup>MUT</sup> breast cancer
Journal Articles

Abstract PD8-06: Phase I/II trial of H3B-6545, a novel selective estrogen receptor covalent antagonist (SERCA), in estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer

Erika P Hamilton, Judy S Wang, Timothy Pluard, Stephen Johnston, Aki Aki Morikawa, Claire E Dees, Robert H Jones, Barbara Haley, Anne Armstrong, Adam L Cohen, Pamela Munster, Gail Wright, Fadi Kayali, Manav Korpal, Lihua Yu, Lisa Cantagallo, Benoit Destenaves, Zhaojie Zhang, Lei Gao, Marc J Pipas, Tarek Sahmouud, Antonio Gualberto, Dejan Juric
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD8-06.
https://doi.org/10.1158/1538-7445.SABCS20-PD8-06
Published: 15 February 2021
View article titled, Abstract PD8-06: Phase I/II trial of H3B-6545, a novel selective estrogen receptor covalent antagonist (SERCA), in estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer
Journal Articles

Abstract CT052: Clinical safety and efficacy study of TruUCAR™ GC027: The first-in-human, universal CAR-T therapy for adult relapsed/refractory T-cell acute lymphoblastic leukemia (r/r T-ALL)

Xinxin Wang, Shiqi Li, Lei Gao, Zhongtao Yuan, Kun Wu, Lin Liu, Le Luo, Yao Liu, Cheng Zhang, Jia Liu, Chunhui Yang, Yu Li, Zhimin Li, Jiaping He, Duanpeng Wang, Xun Ye, Xu Tan, Ruihao Huang, Jianning Ge, Yu Han, Dingsong Zhang, Youcheng Wang, Lihua Fang, Yingnian Chen, Wei Cao, Sanbin Wang, Xi Zhang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT052.
https://doi.org/10.1158/1538-7445.AM2020-CT052
Published: 15 August 2020
View article titled, Abstract CT052: Clinical safety and efficacy study of TruUCAR™ GC027: The first-in-human, universal CAR-T therapy for adult relapsed/refractory T-cell acute lymphoblastic leukemia (r/r T-ALL)
Journal Articles

Correction: SIX1 Promotes Tumor Lymphangiogenesis by Coordinating TGFβ Signals That Increase Expression of VEGF-C

Dan Liu, Li Li, Xiao-Xue Zhang, Dong-Yi Wan, Bi-Xin Xi, Zheng Hu, Wen-Cheng Ding, Da Zhu, Xiao-Li Wang, Wei Wang, Zuo-Hua Feng, Hui Wang, Ding Ma, Qing-Lei Gao
Journal: Cancer Research
Cancer Res (2019) 79 (7): 1715.
https://doi.org/10.1158/0008-5472.CAN-19-0462
Published: 01 April 2019
View article titled, Correction: SIX1 Promotes Tumor Lymphangiogenesis by Coordinating TGFβ Signals That Increase Expression of VEGF-C
Open the PDF for Correction: SIX1 Promotes Tumor Lymphangiogenesis by Coordinating TGFβ Signals That Increase Expression of VEGF-C in another window
Journal Articles

SIX1 Promotes Tumor Lymphangiogenesis by Coordinating TGFβ Signals That Increase Expression of VEGF-C

Dan Liu, Li Li, Xiao-Xue Zhang, Dong-Yi Wan, Bi-Xin Xi, Zheng Hu, Wen-Cheng Ding, Da Zhu, Xiao-Li Wang, Wei Wang, Zuo-Hua Feng, Hui Wang, Ding Ma, Qing-Lei Gao
Journal: Cancer Research
Cancer Res (2014) 74 (19): 5597–5607.
https://doi.org/10.1158/0008-5472.CAN-13-3598
Published: 30 September 2014
View article titled, SIX1 Promotes Tumor Lymphangiogenesis by Coordinating TGFβ Signals That Increase Expression of VEGF-C
Open the PDF for SIX1 Promotes Tumor Lymphangiogenesis by Coordinating TGFβ Signals That Increase Expression of VEGF-C in another window
Includes: Supplementary data
Journal Articles

Helicobacter pylori Infection and Gastric Cancer Risk: Evaluation of 15 H. pylori Proteins Determined by Novel Multiplex Serology

Lei Gao, Angelika Michel, Melanie N. Weck, Volker Arndt, Michael Pawlita, Hermann Brenner
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6164–6170.
https://doi.org/10.1158/0008-5472.CAN-09-0596
Published: 29 July 2009
View article titled, <em>Helicobacter pylori</em> Infection and Gastric Cancer Risk: Evaluation of 15 <em>H. pylori</em> Proteins Determined by Novel Multiplex Serology
Open the PDF for <em>Helicobacter pylori</em> Infection and Gastric Cancer Risk: Evaluation of 15 <em>H. pylori</em> Proteins Determined by Novel Multiplex Serology in another window
Includes: Supplementary data
Journal Articles

Association between Chronic Atrophic Gastritis and Serum Antibodies to 15 Helicobacter pylori Proteins Measured by Multiplex Serology

Lei Gao, Melanie N. Weck, Angelika Michel, Michael Pawlita, Hermann Brenner
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2973–2980.
https://doi.org/10.1158/0008-5472.CAN-08-3477
Published: 01 April 2009
View article titled, Association between Chronic Atrophic Gastritis and Serum Antibodies to 15 <em>Helicobacter pylori</em> Proteins Measured by Multiplex Serology
Open the PDF for Association between Chronic Atrophic Gastritis and Serum Antibodies to 15 <em>Helicobacter pylori</em> Proteins Measured by Multiplex Serology in another window
Includes: Supplementary data