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Journal Articles

Abstract B021: Assessing replication stress as an actionable therapeutic opportunity in chordoma

Nindo Punturi, Wendy Leung, Joan Levy, Lee Zou, Gregory M. Cote, Dan M. Freed
Journal: Cancer Research
Cancer Res (2024) 84 (1_Supplement): B021.
https://doi.org/10.1158/1538-7445.DNAREPAIR24-B021
Published: 09 January 2024
View articletitled, Abstract B021: Assessing replication stress as an actionable therapeutic opportunity in chordoma
Journal Articles

Heterochromatin-Dependent Replication Stress: A Lesson from IDH1/2 Mutants

Lee Zou
Journal: Cancer Research
Cancer Res (2023) 83 (18): 2987–2989.
https://doi.org/10.1158/0008-5472.CAN-23-2015
Published: 15 September 2023
View articletitled, Heterochromatin-Dependent Replication Stress: A Lesson from IDH1/2 Mutants
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Journal Articles

Abstract 6101: PUM3 is a novel R-loop regulator and is essential for efficient DNA damage repair

Chenyu Lin, Jian Ouyang, Robert Wine, Chen Qiu, Jason Williams, Traci M. Hall, Lee Zou, Wayne Miles
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6101.
https://doi.org/10.1158/1538-7445.AM2023-6101
Published: 04 April 2023
View articletitled, Abstract 6101: PUM3 is a novel R-loop regulator and is essential for efficient DNA damage repair
Journal Articles

Abstract 6195: Assessing replication stress as an actionable therapeutic opportunity in chordoma

Nindo Punturi, Lee Dolat, Wendy Leung, Joan Levy, Lee Zou, Daniel M. Freed, Gregory M. Cote
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6195.
https://doi.org/10.1158/1538-7445.AM2023-6195
Published: 04 April 2023
View articletitled, Abstract 6195: Assessing replication stress as an actionable therapeutic opportunity in chordoma
Journal Articles

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

Manav Gupta, Carla P. Concepcion, Caroline G. Fahey, Hasmik Keshishian, Arjun Bhutkar, Christine F. Brainson, Francisco J. Sanchez-Rivera, Patrizia Pessina, Jonathan Y. Kim, Antoine Simoneau, Margherita Paschini, Mary C. Beytagh, Caroline R. Stanclift, Monica Schenone, D.R. Mani, Chendi Li, Audris Oh, Fei Li, Hai Hu, Angeliki Karatza, Roderick T. Bronson, Alice T. Shaw, Aaron N. Hata, Kwok-Kin Wong, Lee Zou, Steven A. Carr, Tyler Jacks, Carla F. Kim
Journal: Cancer Research
Cancer Res (2020) 80 (18): 3841–3854.
https://doi.org/10.1158/0008-5472.CAN-20-1744
Published: 15 September 2020
View articletitled, BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
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Includes: Supplementary data
Journal Articles

Abstract PR09: Cancer-specific retargeting of BAF complexes by a prion-like domain

Gaylor Boulay, Gabriel J. Sandoval, Nicolo Riggi, Sowmya Iyer, Rémi Buisson, Beverly Naigles, Mary E. Awad, Shruthi Rengarajan, Angela Volorio, Matthew J. McBride, Liliane C. Broye, Lee Zou, Ivan Stamenkovic, Cigall Kadoch, Miguel N. Rivera
Journal: Cancer Research
Cancer Res (2018) 78 (19_Supplement): PR09.
https://doi.org/10.1158/1538-7445.PEDCA17-PR09
Published: 01 October 2018
View articletitled, Abstract PR09: Cancer-specific retargeting of BAF complexes by a prion-like domain
Journal Articles

Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes

Hai Dang Nguyen, Wan Yee Leong, Weiling Li, Pavankumar N.G. Reddy, Jack D. Sullivan, Matthew J. Walter, Lee Zou, Timothy A. Graubert
Journal: Cancer Research
Cancer Res (2018) 78 (18): 5363–5374.
https://doi.org/10.1158/0008-5472.CAN-17-3970
Published: 14 September 2018
View articletitled, Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes
Open the PDF for Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes in another window
Includes: Supplementary data
Journal Articles

APOBEC3A and APOBEC3B Activities Render Cancer Cells Susceptible to ATR Inhibition

Rémi Buisson, Michael S. Lawrence, Cyril H. Benes, Lee Zou
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4567–4578.
https://doi.org/10.1158/0008-5472.CAN-16-3389
Published: 31 August 2017
View articletitled, APOBEC3A and APOBEC3B Activities Render Cancer Cells Susceptible to ATR Inhibition
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Includes: Supplementary data
Journal Articles

Abstract 1410: Proliferation during epithelial-to-mesenchymal transition induces genomic instability

Valentine Comaills, Lilian Kabeche, Robert Morris, Min Yu, Marissa Wells Madden, Joseph A. LiCausi, Nicola Aceto, Yu Zheng, David T. Miyamoto, Sridhar Ramaswamy, Lee Zou, Daniel A. Haber, Shyamala Maheswaran
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1410.
https://doi.org/10.1158/1538-7445.AM2017-1410
Published: 01 July 2017
View articletitled, Abstract 1410: Proliferation during epithelial-to-mesenchymal transition induces genomic instability
Journal Articles

EGFR-Activating Mutations Correlate with a Fanconi Anemia–like Cellular Phenotype That Includes PARP Inhibitor Sensitivity

Heike N. Pfäffle, Meng Wang, Liliana Gheorghiu, Natalie Ferraiolo, Patricia Greninger, Kerstin Borgmann, Jeffrey Settleman, Cyril H. Benes, Lecia V. Sequist, Lee Zou, Henning Willers
Journal: Cancer Research
Cancer Res (2013) 73 (20): 6254–6263.
https://doi.org/10.1158/0008-5472.CAN-13-0044
Published: 14 October 2013
View articletitled, EGFR-Activating Mutations Correlate with a Fanconi Anemia–like Cellular Phenotype That Includes PARP Inhibitor Sensitivity
Open the PDF for EGFR-Activating Mutations Correlate with a Fanconi Anemia–like Cellular Phenotype That Includes PARP Inhibitor Sensitivity in another window
Includes: Supplementary data
Journal Articles

Abstract 1358: Discovery and optimization of potent and selective benzonaphthyridinone analogs as dual mTOR/ATR small molecular inhibitors for treatment of cancer

Qingsong Liu, Danny Zhou, Bunsho Shiotani, Nathanael S. Gray, Stephen J. Elledge, Lee Zou
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1358.
https://doi.org/10.1158/1538-7445.AM2011-1358
Published: 15 April 2011
View articletitled, Abstract 1358: Discovery and optimization of potent and selective benzonaphthyridinone analogs as dual mTOR/ATR small molecular inhibitors for treatment of cancer