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Lee M. Graves
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Journal Articles

Abstract 5380: Anticancer compound ONC201 induces prolonged stress and arrest of proliferation in BT474 human breast cancer cells without induction of cell death

Artem A. Mishukov, Irina V. Odinokova, Serazhutdin A. Abdullaev, Vitaly K. Zhalimov, Emily M. Fennel, Lucas J. Aponte-Collazo, Paul R. Graves, Lee M. Graves, Ekhson L. Holmuhamedov
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5380.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5380
Published: 15 June 2022
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Journal Articles

Abstract 991: ONC201 & TR57 reversibly depletes mtDNA content & regulates mitochondrial biogenesis in BT-474, human breast cancer cells

Margarita I. Kobyakova, Serazhutdin Abdullaev, Yana V. Evstratova, Artem Mishukov, Irina Odinokova, Lee M. Graves, Ekhson Holmuhamedov
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 991.
DOI: https://doi.org/10.1158/1538-7445.AM2021-991
Published: 01 July 2021
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Journal Articles

Abstract 2888: Reversible and dose-dependent suppression of motility of human breast cancer cells with ONC201 and/or TR57 in culture

Yana Evstratova, Margarita Kobyakova, Irina Odinokova, Alexander Stolyarov, Artyom Mishukov, Lee M. Graves, Ekhson Holmuhamedov
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2888.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2888
Published: 01 July 2021
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Journal Articles

Abstract 2398: Disruption of mitochondrial metabolism by ClpP activation in triple negative breast cancer

Emily M. Fennell, Lucas J. Aponte-Collazo, Blake R. Rushing, Yuan-Yuan Li, Wimal Pathmasiri, Joshua D. Wynn, Paul R. Graves, Ekhson L. Holmuhamedov, Laura E. Herring, Edwin J. Iwanowicz, Lee M. Graves
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2398.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2398
Published: 01 July 2021
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Journal Articles

Abstract 4794: Mitochondrial matrix protease ClpP agonists inhibit cell growth and cancer stem cell function in breast cancer cells

Yoshimi E. Greer, Lidia Hernandez, Voeller Donna, Raj Chari, Sam Gilbert, Binwu Tang, Christina Annunziata, Lalage Wakefield, Edwin Iwanowicz, Lee M. Graves, Stanley Lipkowitz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4794.
DOI: https://doi.org/10.1158/1538-7445.AM2020-4794
Published: 15 August 2020
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Journal Articles

Abstract 4458: Regulation of MYC protein stability by mutant KRAS in pancreatic ductal adenocarcinoma

Angelina V. Vaseva, Devon R. Blake, Salma H. Azam, Karim T. Gilbert, Chad V. Pecot, Kenneth H. Pearce, Laura E. Herring, Lee M. Graves, Peter J. Houghton, Channing J. Der
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4458.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4458
Published: 01 July 2017
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Journal Articles

Abstract 3586: The use of kinome profiling to determine potential resistance pathways in pancreatic cancer cells treated with PIM kinase inhibitors

Vandana Singh, Brittany Nixon, T.S. Karim Gilbert, Steve Warner, David Bearss, Lee M. Graves, Antonio T. Baines
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3586.
DOI: https://doi.org/10.1158/1538-7445.AM2015-3586
Published: 01 August 2015
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