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Lee A. Albacker
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Journal Articles

Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects

Noboru Ishiyama, Matthew O'Connor, Andrei Salomatov, Darlene Romashko, Shalabh Thakur, Ahmet Mentes, Julia F. Hopkins, Garrett M. Frampton, Lee A. Albacker, Anna Kohlmann, Christopher Roberts, Elizabeth Buck
Journal: Cancer Research
Cancer Res canres.0940.2021.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-0940
Published: 03 May 2022
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Includes: Supplementary data
Journal Articles

Abstract PD9-10: BRE12-158: A post-neoadjuvant, randomized phase 2 trial of personalized therapy vs. treatment of physician’s choice for patients with residual triple negative breast cancer

Bryan P Schneider, Guanglong Jiang, Tarah J Ballinger, Fei Shen, Christopher Chitambar, Rita Nanda, Carla Falkson, Filipa C Lynce, Christopher Gallagher, Claudine Isaacs, Marcelo Blaya, Elisavet Paplomata, Radhika Walling, Karen Daily, Reshma Mahtani, Michael A Thompson, Robert Graham, Maureen E Cooper, Dean C Pavlick, Lee A Albacker, Jeffery Gregg, Jeffery P Solzak, Yu-Hsiang Chen, Casey L Bales, Erica Cantor, Bradley A Hancock, Nawal Kassem, Paul Helft, Bert O'Neil, Anna Maria Storniolo, Sunil Badve, Kathy D Miller, Milan Radovich
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD9-10.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-PD9-10
Published: 15 February 2022
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Journal Articles

Abstract 381: Elevated PARP7 expression in select cancers identifies a target population for RBN-2397 therapy

Jodie Wong, Kristy Kuplast-Barr, Ryan P. Abo, Anupriya S. Kulkarni, Linda T. Nieman, Azfar Neyaz, Katherine H. Xu, Radwa Sharaf, Lee A. Albacker, David T. Ting, Heike Keilhack, Kristen A. McEachern
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 381.
DOI: https://doi.org/10.1158/1538-7445.AM2021-381
Published: 01 July 2021
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Journal Articles

Abstract CT027: TALAPRO-1 final data: Talazoparib (TALA) monotherapy in men with DNA damage response alterations (DDRalt) and metastatic castration-resistant prostate cancer (mCRPC): Exploration of DDRalt germline/somatic origin and zygosity

Johann S. de Bono, A. Douglas Laird, Niven Mehra, Philippe Barthelemy, Remy Delva, Tanya Dorff, Umberto Basso, Adam Stirling, Jean-Pascal Machiels, Herlinde Dumez, Vincent Renard, Julia Hopkins, Lee A. Albacker, Hsiang-Chun Chen, Marielena Mata, Nicola Di Santo, Cynthia Healy, Inge M. van Oort, Giorgio Scagliotti, Karim Fizazi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT027.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT027
Published: 01 July 2021
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Journal Articles

Abstract 2062: Comprehensive molecular profiling of DNA damage response (DDR) deficiencies in advanced solid tumors using a real-world genomic database

Danyi Wang, Brian Elenbaas, Karthikeyan Murugesan, Lee A. Albacker, Julien Doudement, Juergen Scheuenpflug, Giuseppe Locatelli, Zheng Feng
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2062.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2062
Published: 01 July 2021
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Abstract PS5-07: A retrospective analysis of association of MYC and RAD21 amplification with final overall survival (OS) data in the phase 3 EMBRACA study with talazoparib

Johannes Ettl, A. Douglas Laird, Joanne L. Blum, Hope S. Rugo, Sara A. Hurvitz, Miguel Martín, Henri Roché, Young-Hyuck Im, Annabel Goodwin, Rinat Yerushalmi, Tiziana Usari, Silvana Lanzalone, Akos Czibere, Julia Hopkins, Lee A. Albacker, Lida A. Mina, Jennifer K. Litton
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS5-07.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS5-07
Published: 15 February 2021
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Journal Articles

Abstract CT072: Exploration of impact of tumor BRCA zygosity and genomic loss-of-heterozygosity (gLOH) on efficacy in Phase 3 EMBRACA study of talazoparib in patients (pts) with HER2-negative (HER2−) advanced breast cancer (ABC) and a germline BRCA1/2 (gBRCA1/2) mutation

Jennifer K. Litton, A. Douglas Laird, Hope S. Rugo, Johannes Ettl, Sara A. Hurvitz, Miguel Martin, Henri Roché, Young-Hyuck Im, Annabel Goodwin, Joanne L. Blum, Wolfgang Eiermann, Ying Chen, Silvana Lanzalone, Jijumon Chelliserry, Akos Czibere, Lee A. Albacker, Garrett M. Frampton, Lida A. Mina
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT072.
DOI: https://doi.org/10.1158/1538-7445.AM2020-CT072
Published: 15 August 2020
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Journal Articles

Abstract 2337: Pan-cancer analysis of sex differences and their associations with ancestry and genomic biomarkers in a large comprehensive genomic profiling dataset

Benjamin G. Kaplan, Peter Halmos, Justin Y. Newberg, Ethan S. Sokol, Meagan Montesion, Lee A. Albacker, Vincent Miller, Jeff S. Ross, Garrett M. Frampton, Jonathon K. Killian
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2337.
DOI: https://doi.org/10.1158/1538-7445.AM2020-2337
Published: 15 August 2020
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Journal Articles

Abstract 4003: Comprehensive genomic profiling of Merkel cell carcinoma samples reveals bimodal distribution of tumor mutational burden and two mutually exclusive candidate mechanisms of malignant transformation

Meagan Montesion, Ethan S. Sokol, Todd C. Knepper, Andrew S. Brohl, Garrett M. Frampton, Phil J. Stephens, James A. DeCaprio, Kenneth Y. Tsai, Lee A. Albacker
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4003.
DOI: https://doi.org/10.1158/1538-7445.AM2018-4003
Published: 01 July 2018
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Abstract 3406: Comprehensive genomic profiling of hematologic malignancies identifies recurrent somatic splicing factor mutations in non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM)

Lee A. Albacker, Silvia Buonamici, Garrett M. Frampton, Peter Smith, Philip J. Stephens, Markus Warmuth, Ping Zhu, Lihua Yu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3406.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3406
Published: 01 July 2018
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Abstract 1775: The interaction of PD-L1, TMB, and genomic alterations in NSCLC

Michael E. Goldberg, Laurie M. Gay, David Fabrizio, Garrett M. Frampton, Julia A. Elvin, Jeffrey S. Ross, Vincent A. Miller, Philip J. Stephens, Lee A. Albacker
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1775.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1775
Published: 01 July 2017
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High-Throughput Genomic Profiling of Adult Solid Tumors Reveals Novel Insights into Cancer Pathogenesis

Ryan J. Hartmaier, Lee A. Albacker, Juliann Chmielecki, Mark Bailey, Jie He, Michael E. Goldberg, Shakti Ramkissoon, James Suh, Julia A. Elvin, Samuel Chiacchia, Garrett M. Frampton, Jeffrey S. Ross, Vincent Miller, Philip J. Stephens, Doron Lipson
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (9): 2464–2475.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-2479
Published: 30 April 2017
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Includes: Supplementary data
Journal Articles

Abstract PR02: Aneuploidy as a driver of liver cancer

Lee A. Albacker, Floris Foijer, Ying Yue, Darin Takemoto, Stehpanie Davis, Rodney T. Bronson, Peter K. Sorger
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): PR02.
DOI: https://doi.org/10.1158/1538-7445.TRANSCAGEN-PR02
Published: 15 November 2015
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