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Journal Articles

Abstract 6154: Targeted CRISPRi screen identifies functional variants and novel target genes at multiple renal cell carcinoma (RCC) susceptibility loci

Free
Timothy Winter, Timothy Myers, Leandro Colli, Lea Jessop, Jiyeon Choi, Mitchell J. Machiela, Mark P. Purdue, Kevin Brown, Stephen Chanock
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6154.
https://doi.org/10.1158/1538-7445.AM2024-6154
Published: 22 March 2024
View articletitled, Abstract 6154: Targeted CRISPRi screen identifies functional variants and novel target genes at multiple renal cell carcinoma (RCC) susceptibility loci
Journal Articles

Abstract 5239: Integrative analysis of 3D chromatin organization at GWAS loci identifies RAPGEF1 as a melanoma susceptibility gene

Free
Rohit Thakur, Mai Xu, Alexandra Thornock, Hayley Sowards, Epring Long, Thomas Rheling, Karen Funderburk, Jinhu Yin, Rebecca Hennessey, Raj Chari, Tongwu Zhang, Lea Jessop, Timothy Myers, Matthew E. Johnson, Andrew D. Wells, Alessandra Chesi, Struan F. Grant, Mark I. Iles, Maria T. Landi, Matthew Law, Melanoma Meta-Analysis Consortium, Mitchell Machiela, Jiyeon Choi, Leonard I. Zon, Kevin M. Brown
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5239.
https://doi.org/10.1158/1538-7445.AM2023-5239
Published: 04 April 2023
View articletitled, Abstract 5239: Integrative analysis of 3D chromatin organization at GWAS loci identifies RAPGEF1 as a melanoma susceptibility gene
Journal Articles

Abstract SY25-01: Identification of enhancer elements at kidney cancer susceptibility loci using genome-wide approaches in which post-GWAS functional studies implicate the SWI/SNF DPF3 gene for the 14q24 risk locus

Free
Leandro M. Colli, Lea Jessop J. Chanock, Timothy Myers, Mitchell Machiela, Jiyeon Choi, Mark Purdue, Kevin Brown, Stephen J. Chanock
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): SY25-01.
https://doi.org/10.1158/1538-7445.AM2019-SY25-01
Published: 01 July 2019
View articletitled, Abstract SY25-01: Identification of enhancer elements at kidney cancer susceptibility loci using genome-wide approaches in which post-GWAS functional studies implicate the SWI/SNF DPF3 gene for the 14q24 risk locus
Journal Articles

Abstract 1587: Integrated renal cancer post-GWAS functional studies implicates the SWI/SNF DPF3 gene on 14q24 risk locus

Free
Leandro Machado Colli, Lea Jessop, Sabrina Y. Camp, Timothy Myers, Mitchell J. Machiela, Jiyeon Choi, Kai Yu, Mark Purdue, Kevin Brown, Stephen J. Chanock
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1587.
https://doi.org/10.1158/1538-7445.AM2019-1587
Published: 01 July 2019
View articletitled, Abstract 1587: Integrated renal cancer post-GWAS functional studies implicates the SWI/SNF DPF3 gene on 14q24 risk locus
Journal Articles

Abstract 401: Functional characterization of the 14q24 renal cancer susceptibility locus implicates SWI/SNF complex member DPF3 via inhibition of apoptosis

Free
Leandro Machado Colli, Lea Jessop, Timothy A. Myers, Mitchell J. Machiela, Jiyeon Choi, Mark Purdue, Kevin Brown, Stephen J. Chanock
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 401.
https://doi.org/10.1158/1538-7445.AM2018-401
Published: 01 July 2018
View articletitled, Abstract 401: Functional characterization of the 14q24 renal cancer susceptibility locus implicates SWI/SNF complex member DPF3 via inhibition of apoptosis
Journal Articles

Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management

Available to Purchase
Leandro M. Colli, Mitchell J. Machiela, Han Zhang, Timothy A. Myers, Lea Jessop, Olivier Delattre, Kai Yu, Stephen J. Chanock
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3666–3671.
https://doi.org/10.1158/0008-5472.CAN-16-3338
Published: 02 July 2017
View articletitled, Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management
Open the PDF for Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management in another window
Includes: Supplementary data
Journal Articles

Abstract 1443: Identification of enhancer elements at kidney cancer susceptibility loci using MPRA

Free
Leandro Machado Colli, Lea Jessop, Mitchell Machiela, Jiyeon Choi, Timothy Myers, Stephen Chanock
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1443.
https://doi.org/10.1158/1538-7445.AM2017-1443
Published: 01 July 2017
View articletitled, Abstract 1443: Identification of enhancer elements at kidney cancer susceptibility loci using MPRA
Journal Articles

Abstract 2333: Possible prediction of tumor specific checkpoint inhibitor response based on TCGA somatic mutation load

Free
Leandro Machado Colli, Mitchell J. Machiela, Timothy Myers, Lea Jessop, Kai Yu, Stephen J. Chanock
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2333.
https://doi.org/10.1158/1538-7445.AM2016-2333
Published: 15 July 2016
View articletitled, Abstract 2333: Possible prediction of tumor specific checkpoint inhibitor response based on TCGA somatic mutation load
Journal Articles

Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses

Available to Purchase
Leandro M. Colli, Mitchell J. Machiela, Timothy A. Myers, Lea Jessop, Kai Yu, Stephen J. Chanock
Journal: Cancer Research
Cancer Res (2016) 76 (13): 3767–3772.
https://doi.org/10.1158/0008-5472.CAN-16-0170
Published: 30 June 2016
View articletitled, Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses
Open the PDF for Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses in another window
Includes: Supplementary data
Journal Articles

Abstract 5061: Post-GWAS functional characterization of the 12p11.23 renal cancer susceptibility locus implicates BHLHE41

Free
Lea Jessop, Pierre Bigot, Mitchell Machiela, Timothy Myers, Nilabja Sikdar, Leandro Colli, Stephen Chanock
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5061.
https://doi.org/10.1158/1538-7445.AM2014-5061
Published: 01 October 2014
View articletitled, Abstract 5061: Post-GWAS functional characterization of the 12p11.23 renal cancer susceptibility locus implicates BHLHE41