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Lawrence J. Marnett
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Journal Articles

Abstract CT111: Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa

Laura Reyes Uribe, Wenhui Wu, Ozkan Gelincik, Prashant V. Bommi, Alejandro Francisco-Cruz, Luisa M. Solis, Patrick M. Lynch, Ramona Lim, Elena Stoffel, Priyanka Kanth, N. Jewel Samadder, Maureen E. Mork, Melissa W. Taggart, Ginger L. Milne, Lawrence J. Marnett, Lana Vornik, Diane D. Liu, Maria Revuelta, Kyle Chang, Y. Nancy You, Levy Kopelovich, Ignacio I. Wistuba, J. Jack Lee, Shizuko Sei, Robert H. Shoemaker, Eva Szabo, Ellen Richmond, Asad Umar, Marjorie Perloff, Powell H. Brown, Steven M. Lipkin, Eduardo Vilar
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT111.
https://doi.org/10.1158/1538-7445.AM2020-CT111
Published: 15 August 2020
View article titled, Abstract CT111: Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa
Journal Articles

Abstract CT065: A phase Ib biomarker trial of naproxen in patients at risk for DNA mismatch repair deficient colorectal cancer

Laura Reyes Uribe, Ramona Lin, Elena M. Stoffel, N. Jewel Samadder, Patrick Lynch, Priyanka Kanth, Ginger Milne, Lawrence J. Marnett, Valerie Sepeda, Diane D Liu, Y. Nancy You, Lana A. Vornik, J. Jack Lee, Ellen Richmond, Asad Umar, Marjorie Perloff, Steven M. Lipkin, Powel H. Brown, Eduardo Vilar-Sanchez
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT065.
https://doi.org/10.1158/1538-7445.AM2018-CT065
Published: 01 July 2018
View article titled, Abstract CT065: A phase Ib biomarker trial of naproxen in patients at risk for DNA mismatch repair deficient colorectal cancer
Journal Articles

Abstract 3050: Proteotoxic isolevuglandins are a central feature of radiation-induced pulmonary injury

Stacy Mont, Sean S. Davies, L Jackson Roberts, Raymond L. Mernaugh, W Hayes McDonald, Brahm H. Segal, Jonathan A. Kropski, Timothy S. Blackwell, Konjeti R. Sekhar, James J. Galligan, Lawrence J. Marnett, Michael L. Freeman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3050.
https://doi.org/10.1158/1538-7445.AM2016-3050
Published: 15 July 2016
View article titled, Abstract 3050: Proteotoxic isolevuglandins are a central feature of radiation-induced pulmonary injury
Journal Articles

Abstract 2068: Cyclooxygenase-1 gene expression contributes to multiple oncogenic pathways in high grade serous ovarian cancer

Andrew J. Wilson, Brian D. Lehmann, Jeanette Saskowski, MD Jashim Uddin, Cristina Daniel, Brenda C. Crews, Qi Liu, Shilin Zhao, Deok-Soo Son, Jennifer A. Pietenpol, Lawrence J. Marnett, Dineo Khabele
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2068.
https://doi.org/10.1158/1538-7445.AM2015-2068
Published: 01 August 2015
View article titled, Abstract 2068: Cyclooxygenase-1 gene expression contributes to multiple oncogenic pathways in high grade serous ovarian cancer
Journal Articles

Abstract 4928: Cyclooxygenase-1 as a target for molecular imaging of high grade serous ovarian cancer

Andrew J. Wilson, Brian D. Lehmann, MD Jashim Ussin, Anna Elleman, Brenda Crews, Jeanette Saskowski, Jennifer Pietenpol, Lawrence J. Marnett, Dineo Khabele
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4928.
https://doi.org/10.1158/1538-7445.AM2014-4928
Published: 01 October 2014
View article titled, Abstract 4928: Cyclooxygenase-1 as a target for molecular imaging of high grade serous ovarian cancer
Journal Articles

Abstract B16: Development of potent and selective indomethacin analogs for the inhibition of AKR1C3 (type 5 17β-hydroxysteroid dehydrogenase) in CRPC

Adegoke Adeniji, Andrew Liedkte, Michael C. Byrns, M Chen, Yi Jin, David Christianson, Lawrence J. Marnett, Trevor M. Penning
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): B16.
https://doi.org/10.1158/1538-7445.PRCA2012-B16
Published: 09 May 2013
View article titled, Abstract B16: Development of potent and selective indomethacin analogs for the inhibition of AKR1C3 (type 5 17β-hydroxysteroid dehydrogenase) in CRPC
Journal Articles

Abstract 2062: Peptidylprolyl cis/trans isomerase A1 (Pin1) is modified by lipid electrophiles generated during oxidative stress

Christopher D. Aluise, Lawrence J. Marnett
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2062.
https://doi.org/10.1158/1538-7445.AM2012-2062
Published: 15 April 2012
View article titled, Abstract 2062: Peptidylprolyl cis/trans isomerase A1 (Pin1) is modified by lipid electrophiles generated during oxidative stress
Journal Articles

Abstract 5733: Detection of M1dG and 6-oxo-M1dG from biological samples in rats

Sarah C. Shuck, Philip J. Kingsley, Dapo Akingbade, Lawrence J. Marnett
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5733.
https://doi.org/10.1158/1538-7445.AM2012-5733
Published: 15 April 2012
View article titled, Abstract 5733: Detection of M1dG and 6-oxo-M1dG from biological samples in rats
Journal Articles

Selective Visualization of Cyclooxygenase-2 in Inflammation and Cancer by Targeted Fluorescent Imaging Agents

Md. Jashim Uddin, Brenda C. Crews, Anna L. Blobaum, Philip J. Kingsley, D. Lee Gorden, J. Oliver McIntyre, Lynn M. Matrisian, Kotha Subbaramaiah, Andrew J. Dannenberg, David W. Piston, Lawrence J. Marnett
Journal: Cancer Research
Cancer Res (2010) 70 (9): 3618–3627.
https://doi.org/10.1158/0008-5472.CAN-09-2664
Published: 28 April 2010
View article titled, Selective Visualization of Cyclooxygenase-2 in Inflammation and Cancer by Targeted Fluorescent Imaging Agents
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Includes: Supplementary data
Journal Articles

Oxidative metabolism of an endogenously produced DNA adduct, M1dG: A novel approach to biomarker discovery.

Charles G. Knutson, Michael Otteneder, Muhammed F. Hashim, Markus Voehler, James N. Riggins, Rory P. Remmel, Carol A. Rouzer, Lawrence J. Marnett
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 86.
Published: 01 May 2005
View article titled, Oxidative metabolism of an endogenously produced DNA adduct, M1dG: A novel approach to biomarker discovery.
Journal Articles

Thromboxane A2 Is a Mediator of Cyclooxygenase-2-dependent Endothelial Migration and Angiogenesis

Thomas O. Daniel, Hua Liu, Jason D. Morrow, Brenda C. Crews, Lawrence J. Marnett
Journal: Cancer Research
Cancer Res (1999) 59 (18): 4574–4577.
Published: 15 September 1999
View article titled, Thromboxane A<sub>2</sub> Is a Mediator of Cyclooxygenase-2-dependent Endothelial Migration and Angiogenesis
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Journal Articles

Modulation of Oxidant Formation in Mouse Skin in Vivo by Tumor-promoting Phorbol Esters

Lawrence J. Marnett, Chuan Ji
Journal: Cancer Research
Cancer Res (1994) 54 (7_Supplement): 1886s–1889s.
Published: 01 April 1994
View article titled, Modulation of Oxidant Formation in Mouse Skin <em>in Vivo</em> by Tumor-promoting Phorbol Esters
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Journal Articles

Summary of the Round Table Discussion on Strategies for Cancer Prevention: Diet, Food, Additives, Supplements, and Drugs

Kathy J. Helzlsouer, Gladys Block, Jeffrey Blumberg, Anthony T. Diplock, Mark Levine, Lawrence J. Marnett, Robert J. Schulplein, Joseph T. Spence, Michael G. Simic
Journal: Cancer Research
Cancer Res (1994) 54 (7_Supplement): 2044s–2051s.
Published: 01 April 1994
View article titled, Summary of the Round Table Discussion on Strategies for Cancer Prevention: Diet, Food, Additives, Supplements, and Drugs
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Journal Articles

Endogenous 12(S)-HETE Production by Tumor Cells and Its Role in Metastasis

Yong Q. Chen, Zofia M. Duniec, Bin Liu, Wolfgang Hagmann, Xiang Gao, Katsu-ichi Shimoji, Lawrence J. Marnett, Carl R. Johnson, Kenneth V. Honn
Journal: Cancer Research
Cancer Res (1994) 54 (6): 1574–1579.
Published: 01 March 1994
View article titled, Endogenous 12(<em>S</em>)-HETE Production by Tumor Cells and Its Role in Metastasis
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Journal Articles

Tumor Cell-derived 12(S)-Hydroxyeicosatetraenoic Acid Induces Microvascular Endothelial Cell Retraction

Kenneth V. Honn, Dean G. Tang, Irma Grossi, Zofia M. Duniec, Jozsef Timar, Colette Renaud, Marie Leithauser, Ian Blair, Carl R. Johnson, Clement A. Diglio, Victoria A. Kimler, John D. Taylor, Lawrence J. Marnett
Journal: Cancer Research
Cancer Res (1994) 54 (2): 565–574.
Published: 01 January 1994
View article titled, Tumor Cell-derived 12(<em>S</em>)-Hydroxyeicosatetraenoic Acid Induces Microvascular Endothelial Cell Retraction
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Journal Articles

Aspirin and the Potential Role of Prostaglandins in Colon Cancer

Lawrence J. Marnett
Journal: Cancer Research
Cancer Res (1992) 52 (20): 5575–5589.
Published: 01 October 1992
View article titled, Aspirin and the Potential Role of Prostaglandins in Colon Cancer
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Journal Articles

Roles of Individual Human Cytochrome P-450 Enzymes in the Bioactivation of Benzo(a)pyrene, 7,8-Dihydroxy-7,8-dihydrobenzo(a)pyrene, and Other Dihydrodiol Derivatives of Polycyclic Aromatic Hydrocarbons

Tsutomu Shimada, Martha V. Martin, Donna Pruess-Schwartz, Lawrence J. Marnett, F. Peter Guengerich
Journal: Cancer Research
Cancer Res (1989) 49 (22): 6304–6312.
Published: 01 November 1989
View article titled, Roles of Individual Human Cytochrome P-450 Enzymes in the Bioactivation of Benzo(<em>a</em>)pyrene, 7,8-Dihydroxy-7,8-dihydrobenzo(<em>a</em>)pyrene, and Other Dihydrodiol Derivatives of Polycyclic Aromatic Hydrocarbons
Open the PDF for Roles of Individual Human Cytochrome P-450 Enzymes in the Bioactivation of Benzo(<em>a</em>)pyrene, 7,8-Dihydroxy-7,8-dihydrobenzo(<em>a</em>)pyrene, and Other Dihydrodiol Derivatives of Polycyclic Aromatic Hydrocarbons in another window
Journal Articles

Peroxyl Radical- and Cytochrome P-450-dependent Metabolic Activation of (+)-7,8-Dihydroxy-7,8-dihydrobenzo(a)pyrene in Mouse Skin in Vitro and in Vivo

Donna Pruess-Schwartz, Annette Nimesheim, Lawrence J. Marnett
Journal: Cancer Research
Cancer Res (1989) 49 (7): 1732–1737.
Published: 01 April 1989
View article titled, Peroxyl Radical- and Cytochrome P-450-dependent Metabolic Activation of (+)-7,8-Dihydroxy-7,8-dihydrobenzo(<em>a</em>)pyrene in Mouse Skin <em>in Vitro</em> and <em>in Vivo</em>
Open the PDF for Peroxyl Radical- and Cytochrome P-450-dependent Metabolic Activation of (+)-7,8-Dihydroxy-7,8-dihydrobenzo(<em>a</em>)pyrene in Mouse Skin <em>in Vitro</em> and <em>in Vivo</em> in another window
Journal Articles

Role of Tumor Cell Cytoskeleton and Membrane Glycoprotein IRGpIIb/IIIa in Platelet Adhesion to Tumor Cell Membrane and Tumor Cell-induced Platelet Aggregation

Hemi Chopra, James S. Hatfield, Young Sook Chang, Irma M. Grossi, Laurence A. Fitzgerald, Coleen Y. O'Gara, Lawrence J. Marnett, Clement A. Diglio, John D. Taylor, Kenneth V. Honn
Journal: Cancer Research
Cancer Res (1988) 48 (13): 3787–3800.
Published: 01 July 1988
View article titled, Role of Tumor Cell Cytoskeleton and Membrane Glycoprotein IRGpIIb/IIIa in Platelet Adhesion to Tumor Cell Membrane and Tumor Cell-induced Platelet Aggregation
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Journal Articles

Structural Requirements for Stimulation of Colonic Cell Proliferation by Oxidized Fatty Acids

Arthur W. Bull, Norman D. Nigro, Lawrence J. Marnett
Journal: Cancer Research
Cancer Res (1988) 48 (7): 1771–1776.
Published: 01 April 1988
View article titled, Structural Requirements for Stimulation of Colonic Cell Proliferation by Oxidized Fatty Acids
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