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Journal Articles

Abstract 3028: Tolerance and intolerance of proximal thymine glycol in DNA double-strand break repair by nonhomologous end joining

Duaa Bafail, Sri Lakshmi Chalasani, Mohammed Al mohaini, Konstantin Akopiants, Lawrence F. Povirk

Cancer Res (2015) 75 (15_Supplement): 3028.

https://doi.org/10.1158/1538-7445.AM2015-3028

Published: 01 August 2015

View articletitled, Abstract 3028: Tolerance and intolerance of proximal thymine glycol in DNA double-strand break repair by nonhomologous end joining

Journal Articles

Abstract 3923: ATM and KAP1 are required for nonhomologous end-joining in transcriptionally active chromatin

Amy J. Hawkins, David E. White, Sarah E. Golding, Konstantin Akopiants, Frank J. Rauscher, Lawrence F. Povirk, Kristoffer Valerie

Cancer Res (2010) 70 (8_Supplement): 3923.

https://doi.org/10.1158/1538-7445.AM10-3923

Published: 15 April 2010

View articletitled, Abstract 3923: ATM and KAP1 are required for nonhomologous end-joining in transcriptionally active chromatin

Journal Articles

Extracellular Signal-Related Kinase Positively Regulates Ataxia Telangiectasia Mutated, Homologous Recombination Repair, and the DNA Damage Response

Sarah E. Golding, Elizabeth Rosenberg, Steven Neill, Paul Dent, Lawrence F. Povirk, Kristoffer Valerie

Cancer Res (2007) 67 (3): 1046–1053.

https://doi.org/10.1158/0008-5472.CAN-06-2371

Published: 05 February 2007

View articletitled, Extracellular Signal-Related Kinase Positively Regulates Ataxia Telangiectasia Mutated, Homologous Recombination Repair, and the DNA Damage Response

Includes: Supplementary data

Journal Articles

MAPK signaling pathways positively and negatively regulate homologous recombination repair

Sarah E. Golding, Steven Neill, Paul Dent, Lawrence F. Povirk, Kristoffer C. Valerie

Cancer Res (2006) 66 (8_Supplement): 1029–1030.

Published: 15 April 2006

View articletitled, MAPK signaling pathways positively and negatively regulate homologous recombination repair

Journal Articles

Nonhomologous DNA end joining at locally multiply damaged sites: tolerance for 8-oxoguanine and dihydrothymine in alignment-based gap filling of double-strand break ends by DNA polymerase lambda

Ruizhe Zhou, Kasia Bebenek, Miguel Garcia-Diaz, Thomas A. Kunkel, Lawrence F. Povirk

Cancer Res (2006) 66 (8_Supplement): 546.

Published: 15 April 2006

View articletitled, Nonhomologous DNA end joining at locally multiply damaged sites: tolerance for 8-oxoguanine and dihydrothymine in alignment-based gap filling of double-strand break ends by DNA polymerase lambda

Journal Articles

Hypersensitivity of Artemis-deficient cells to 3’-phosphoglycolate DNA double-strand breaks, and processing of model 3’-phosphoglycolate double-strand breaks by Artemis in vitro

Tong Zhou, Lawrence F. Povirk, Ruizhe Zhou, Morton J. Cowan, Steven M. Yannone

Cancer Res (2006) 66 (8_Supplement): 545.

Published: 15 April 2006

View articletitled, Hypersensitivity of Artemis-deficient cells to 3’-phosphoglycolate DNA double-strand breaks, and processing of model 3’-phosphoglycolate double-strand breaks by Artemis in vitro

Journal Articles

Radiosensitivity and deficiency in processing of 3’-phosphoglycolate-terminated DNA double-strand breaks in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)

Haritha Tatavarthi, Tong Zhou, Jae W. Lee, Kristoffer Valerie, James R. Lupski, Susan P. Lees-Miller, Lawrence F. Povirk

Cancer Res (2005) 65 (9_Supplement): 469.

Published: 01 May 2005

View articletitled, Radiosensitivity and deficiency in processing of 3’-phosphoglycolate-terminated DNA double-strand breaks in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)

Journal Articles

A fragment of the XRCC4 protein expressed from adenovirus sensitizes MDA-MB231 breast tumor cells to ionizing radiation

Kara R. Jones, Kris C. Valerie, Lawrence F. Povirk, David G. Schatz, Steven M. Yannone, David A. Gewirtz

Cancer Res (2005) 65 (9_Supplement): 339–340.

Published: 01 May 2005

View articletitled, A fragment of the XRCC4 protein expressed from adenovirus sensitizes MDA-MB231 breast tumor cells to ionizing radiation

Journal Articles

Ionizing radiation-induced senescence of breast tumor cells is dependent on p53 and associated with telomere dysfunction.

Kara R. Jones, Lynne W. Elmore, Shawn E. Holt, Colleen Jackson-Cook, Lawrence F. Povirk, David A. Gewirtz

Cancer Res (2004) 64 (7_Supplement): 558.

Published: 01 April 2004

View articletitled, Ionizing radiation-induced senescence of breast tumor cells is dependent on p53 and associated with telomere dysfunction.

Journal Articles

Requirement for XRCC4 and DNA Ligase IV in Alignment-based Gap Filling for Nonhomologous DNA End Joining in Vitro

Jae Wan Lee, Steven M. Yannone, David J. Chen, Lawrence F. Povirk

Cancer Res (2003) 63 (1): 22–24.

Published: 01 January 2003

View articletitled, Requirement for XRCC4 and DNA Ligase IV in Alignment-based Gap Filling for Nonhomologous DNA End Joining in Vitro

Journal Articles

Enhanced Amsacrine-induced Mutagenesis in Plateau-Phase Chinese Hamster Ovary Cells, with Targeting of +1 Frameshifts to Free 3′ Ends of Topoisomerase II Cleavable Complexes

Kathleen Patteson, Peng Wang, Lawrence F. Povirk

Cancer Res (1999) 59 (15): 3682–3688.

Published: 01 August 1999

View articletitled, Enhanced Amsacrine-induced Mutagenesis in Plateau-Phase Chinese Hamster Ovary Cells, with Targeting of +1 Frameshifts to Free 3′ Ends of Topoisomerase II Cleavable Complexes

Journal Articles

A Precise Interchromosomal Reciprocal Exchange between Hot Spots for Cleavable Complex Formation by Topoisomerase II in Amsacrine-treated Chinese Hamster Ovary Cells

Rui-Hua Zhou, Peng Wang, Ying Zou, Colleen K. Jackson-Cook, Lawrence F. Povirk

Cancer Res (1997) 57 (21): 4699–4702.

Published: 01 November 1997

View articletitled, A Precise Interchromosomal Reciprocal Exchange between Hot Spots for Cleavable Complex Formation by Topoisomerase II in Amsacrine-treated Chinese Hamster Ovary Cells

Journal Articles

Induction of Apoptotic DNA Fragmentation and Cell Death in HL-60 Human Promyelocytic Leukemia Cells by Pharmacological Inhibitors of Protein Kinase C

W. David Jarvis, Amy J. Turner, Lawrence F. Povirk, Rebecca S. Traylor, Steven Grant

Cancer Res (1994) 54 (7): 1707–1714.

Published: 01 April 1994

View articletitled, Induction of Apoptotic DNA Fragmentation and Cell Death in HL-60 Human Promyelocytic Leukemia Cells by Pharmacological Inhibitors of Protein Kinase C

Journal Articles

Dissociation between Bulk Damage to DNA and the Antiproliferative Activity of Teniposide (VM-26) in the MCF-7 Breast Tumor Cell Line: Evidence for Induction of Gene-specific Damage and Alterations in Gene Expression

David A. Gewirtz, Michael S. Orr, Frank A. Fornari, Joyce K. Randolph, Jack C. Yalowich, Mary K. Ritke, Lawrence F. Povirk, Roderick T. Bunch

Cancer Res (1993) 53 (15): 3547–3554.

Published: 01 August 1993

View articletitled, Dissociation between Bulk Damage to DNA and the Antiproliferative Activity of Teniposide (VM-26) in the MCF-7 Breast Tumor Cell Line: Evidence for Induction of Gene-specific Damage and Alterations in Gene Expression

Journal Articles

Melphalan-induced Mutagenesis in an SV40-based Shuttle Vector: Predominance of A · T→T · A Transversions

Peng Wang, Richard A. O. Bennett, Lawrence F. Povirk

Cancer Res (1990) 50 (23): 7527–7531.

Published: 01 December 1990

View articletitled, Melphalan-induced Mutagenesis in an SV40-based Shuttle Vector: Predominance of A · T→T · A Transversions

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Abstract 3028: Tolerance and intolerance of proximal thymine glycol in DNA double-strand break repair by nonhomologous end joining

Abstract 3923: ATM and KAP1 are required for nonhomologous end-joining in transcriptionally active chromatin

Extracellular Signal-Related Kinase Positively Regulates Ataxia Telangiectasia Mutated, Homologous Recombination Repair, and the DNA Damage Response

MAPK signaling pathways positively and negatively regulate homologous recombination repair

Nonhomologous DNA end joining at locally multiply damaged sites: tolerance for 8-oxoguanine and dihydrothymine in alignment-based gap filling of double-strand break ends by DNA polymerase lambda

Hypersensitivity of Artemis-deficient cells to 3’-phosphoglycolate DNA double-strand breaks, and processing of model 3’-phosphoglycolate double-strand breaks by Artemis in vitro

Radiosensitivity and deficiency in processing of 3’-phosphoglycolate-terminated DNA double-strand breaks in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)

A fragment of the XRCC4 protein expressed from adenovirus sensitizes MDA-MB231 breast tumor cells to ionizing radiation

Ionizing radiation-induced senescence of breast tumor cells is dependent on p53 and associated with telomere dysfunction.

Requirement for XRCC4 and DNA Ligase IV in Alignment-based Gap Filling for Nonhomologous DNA End Joining in Vitro

Enhanced Amsacrine-induced Mutagenesis in Plateau-Phase Chinese Hamster Ovary Cells, with Targeting of +1 Frameshifts to Free 3′ Ends of Topoisomerase II Cleavable Complexes

A Precise Interchromosomal Reciprocal Exchange between Hot Spots for Cleavable Complex Formation by Topoisomerase II in Amsacrine-treated Chinese Hamster Ovary Cells

Induction of Apoptotic DNA Fragmentation and Cell Death in HL-60 Human Promyelocytic Leukemia Cells by Pharmacological Inhibitors of Protein Kinase C

Dissociation between Bulk Damage to DNA and the Antiproliferative Activity of Teniposide (VM-26) in the MCF-7 Breast Tumor Cell Line: Evidence for Induction of Gene-specific Damage and Alterations in Gene Expression

Melphalan-induced Mutagenesis in an SV40-based Shuttle Vector: Predominance of A · T→T · A Transversions

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