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Lawrence E. Williams
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Journal Articles

Radioiodinated versus Radiometal-Labeled Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments: Optimal Pharmacokinetics for Therapy

Vania Kenanova, Tove Olafsen, Lawrence E. Williams, Nora H. Ruel, Jeffrey Longmate, Paul J. Yazaki, John E. Shively, David Colcher, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2007) 67 (2): 718–726.
https://doi.org/10.1158/0008-5472.CAN-06-0454
Published: 18 January 2007
View article titled, Radioiodinated versus Radiometal-Labeled Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments: Optimal Pharmacokinetics for Therapy
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Journal Articles

Optimizing Radiolabeled Engineered Anti-p185HER2 Antibody Fragments for In vivo Imaging

Tove Olafsen, Vania E. Kenanova, Gobalakrishnan Sundaresan, Anne-Line Anderson, Desiree Crow, Paul J. Yazaki, Lin Li, Michael F. Press, Sanjiv S. Gambhir, Lawrence E. Williams, Jeffrey Y.C. Wong, Andrew A. Raubitschek, John E. Shively, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5907–5916.
https://doi.org/10.1158/0008-5472.CAN-04-4472
Published: 01 July 2005
View article titled, Optimizing Radiolabeled Engineered Anti-p185<sup>HER2</sup> Antibody Fragments for <em>In vivo</em> Imaging
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Includes: Supplementary data
Journal Articles

Engineered anti-CEA scFv-Fc antibody fragments tailored for pharmacokinetic and imaging properties

Vania E. Kenanova, Tove Olafsen, Gobalakrishnan Sundaresan, Murugesan Subbarayan, Lawrence E. Williams, John E. Shively, David Colcher, Sanjiv S. Gambhir, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1243.
Published: 01 May 2005
View article titled, Engineered anti-CEA scFv-Fc antibody fragments tailored for pharmacokinetic and imaging properties
Journal Articles

MicroPET imaging of breast cancer xenografts with anti-p185HER2 minibody and scFv-Fc antibody fragments

Tove Olafsen, Vania E. Kenanova, Gobalakrishnan Sundaresan, Anne-Line Anderson, Michael F. Press, Sanjiv S. Gambhir, Lawrence E. Williams, Andrew A. Raubitschek, John E. Shively, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 899–900.
Published: 01 May 2005
View article titled, MicroPET imaging of breast cancer xenografts with anti-p185<sup>HER2</sup> minibody and scFv-Fc antibody fragments
Journal Articles

Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments

Vania Kenanova, Tove Olafsen, Desiree M. Crow, Gobalakrishnan Sundaresan, Murugesan Subbarayan, Nora H. Carter, David N. Ikle, Paul J. Yazaki, Arion F. Chatziioannou, Sanjiv S. Gambhir, Lawrence E. Williams, John E. Shively, David Colcher, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (2): 622–631.
https://doi.org/10.1158/0008-5472.622.65.2
Published: 03 February 2005
View article titled, Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments
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Journal Articles

Targeting and Therapy of Carcinoembryonic Antigen-expressing Tumors in Transgenic Mice with an Antibody-Interleukin 2 Fusion Protein

Xiaochuan Xu, Patrick Clarke, György Szalai, John E. Shively, Lawrence E. Williams, Yu Shyr, Ergang Shi, F. James Primus
Journal: Cancer Research
Cancer Res (2000) 60 (16): 4475–4484.
Published: 01 August 2000
View article titled, Targeting and Therapy of Carcinoembryonic Antigen-expressing Tumors in Transgenic Mice with an Antibody-Interleukin 2 Fusion Protein
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Journal Articles

Minibody: A Novel Engineered Anti-Carcinoembryonic Antigen Antibody Fragment (Single-Chain Fv-CH3) Which Exhibits Rapid, High-Level Targeting of Xenografts

Shi-zhen Hu, Louise Shively, Andrew Raubitschek, Mark Sherman, Lawrence E. Williams, Jeffrey Y. C. Wong, John E. Shively, Anna M. Wu
Journal: Cancer Research
Cancer Res (1996) 56 (13): 3055–3061.
Published: 01 July 1996
View article titled, Minibody: A Novel Engineered Anti-Carcinoembryonic Antigen Antibody Fragment (Single-Chain Fv-C<sub>H</sub>3) Which Exhibits Rapid, High-Level Targeting of Xenografts
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Journal Articles

Initial Experience Evaluating 90Yttrium-Radiolabeled Anti-Carcinoembryonic Antigen Chimeric T84.66 in a Phase I Radioimmunotherapy Trial

Jeffrey Y. C. Wong, Lawrence E. Williams, David M. Yamauchi, Tamara Odom-Maryon, Jose M. Esteban, Michael Neumaier, Anna M. Wu, David K. Johnson, F. James Primus, John E. Shively, Andrew A. Raubitschek
Journal: Cancer Research
Cancer Res (1995) 55 (23_Supplement): 5929s–5934s.
Published: 01 December 1995
View article titled, Initial Experience Evaluating <sup>90</sup>Yttrium-Radiolabeled Anti-Carcinoembryonic Antigen Chimeric T84.66 in a Phase I Radioimmunotherapy Trial
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Journal Articles

Comparison of Immunoscintigraphy and Computerized Tomography in Identifying Colorectal Cancer: Individual Lesion Analysis

Raffael M. Corbisiero, Dave M. Yamauchi, Lawrence E. Williams, Jose M. Esteban, Tamara Odom-Maryon, J. David Beatty
Journal: Cancer Research
Cancer Res (1991) 51 (20): 5704–5711.
Published: 01 October 1991
View article titled, Comparison of Immunoscintigraphy and Computerized Tomography in Identifying Colorectal Cancer: Individual Lesion Analysis
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Journal Articles

Interferon Enhancement of Radioimmunotherapy for Colon Carcinoma

Joseph A. Kuhn, Barbara G. Beatty, Jeffrey Y. C. Wong, Jose M. Esteban, Philip M. Wanek, Francis Wall, Robert R. Buras, Lawrence E. Williams, J. David Beatty
Journal: Cancer Research
Cancer Res (1991) 51 (9): 2335–2339.
Published: 01 May 1991
View article titled, Interferon Enhancement of Radioimmunotherapy for Colon Carcinoma
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Journal Articles

Estimation of Monoclonal Antibody-associated 90Y Activity Needed to Achieve Certain Tumor Radiation Doses in Colorectal Cancer Patients

Lawrence E. Williams, Barbara G. Beatty, J. David Beatty, Jeffrey Y. C. Wong, Raymond J. Paxton, John E. Shively
Journal: Cancer Research
Cancer Res (1990) 50 (3_Supplement): 1029s–1030s.
Published: 01 February 1990
View article titled, Estimation of Monoclonal Antibody-associated <sup>90</sup>Y Activity Needed to Achieve Certain Tumor Radiation Doses in Colorectal Cancer Patients
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Journal Articles

Presurgical Imaging with Indium-labeled Anti-Carcinoembryonic Antigen for Colon Cancer Staging

J. David Beatty, Lawrence E. Williams, David Yamauchi, Blaine A. Morton, L. Robert Hill, Barbara G. Beatty, Raymond J. Paxton, Bruce Merchant, John E. Shively
Journal: Cancer Research
Cancer Res (1990) 50 (3_Supplement): 922s–926s.
Published: 01 February 1990
View article titled, Presurgical Imaging with Indium-labeled Anti-Carcinoembryonic Antigen for Colon Cancer Staging
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Journal Articles

Effect of Specific Antibody Pretreatment on Liver Uptake of 111In-labeled Anticarcinoembryonic Antigen Monoclonal Antibody in Nude Mice Bearing Human Colon Cancer Xenografts

Barbara G. Beatty, J. David Beatty, Lawrence E. Williams, Raymond J. Paxton, John E. Shively, Margaret O'Connor-Tressel
Journal: Cancer Research
Cancer Res (1989) 49 (6): 1587–1594.
Published: 01 March 1989
View article titled, Effect of Specific Antibody Pretreatment on Liver Uptake of <sup>111</sup>In-labeled Anticarcinoembryonic Antigen Monoclonal Antibody in Nude Mice Bearing Human Colon Cancer Xenografts
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Journal Articles

Testis Imaging with 111In-labeled Anticarcinoembryonic Antigen Monoclonal Antibody: Identification of Carcinoembryonic Antigen in Normal Germ Cells

Barbara G. Beatty, Raymond J. Paxton, Khalil Sheibani, Rosemary B. Duda, Lawrence E. Williams, John E. Shively, J. David Beatty
Journal: Cancer Research
Cancer Res (1986) 46 (12_Part_1): 6503–6508.
Published: 01 December 1986
View article titled, Testis Imaging with <sup>111</sup>In-labeled Anticarcinoembryonic Antigen Monoclonal Antibody: Identification of Carcinoembryonic Antigen in Normal Germ Cells
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Journal Articles

Preoperative Imaging of Colorectal Carcinoma with 111In-labeled Anticarcinoembryonic Antigen Monoclonal Antibody

J. David Beatty, Rosemary B. Duda, Lawrence E. Williams, Khalil Sheibani, Raymond J. Paxton, Barbara G. Beatty, Vicki J. Philben, John L. Werner, John E. Shively, William G. Vlahos, William A. Kokal, Daniel U. Riihimaki, Jose J. Terz, Lawrence D. Wagman
Journal: Cancer Research
Cancer Res (1986) 46 (12_Part_1): 6494–6502.
Published: 01 December 1986
View article titled, Preoperative Imaging of Colorectal Carcinoma with <sup>111</sup>In-labeled Anticarcinoembryonic Antigen Monoclonal Antibody
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Journal Articles

High-Specific-Activity 111In-labeled Anticarcinoembryonic Antigen Monoclonal Antibody: Improved Method for the Synthesis of Diethylenetriaminepentaacetic Acid Conjugates

Raymond J. Paxton, James G. Jakowatz, J. David Beatty, Barbara G. Beatty, William G. Vlahos, Lawrence E. Williams, Brian R. Clark, John E. Shively
Journal: Cancer Research
Cancer Res (1985) 45 (11_Part_2): 5694–5699.
Published: 01 November 1985
View article titled, High-Specific-Activity <sup>111</sup>In-labeled Anticarcinoembryonic Antigen Monoclonal Antibody: Improved Method for the Synthesis of Diethylenetriaminepentaacetic Acid Conjugates
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Journal Articles

High-Specific-Activity 111In-labeled Anticarcinoembryonic Antigen Monoconal Antibody: Biodistribution and Imaging in Nude Mice Bearing Human Colon Cancer Xenografts

James G. Jakowatz, Barbara G. Beatty, William G. Vlahos, David Porudominsky, Vicki J. Philben, Lawrence E. Williams, Raymond J. Paxton, John E. Shively, J. David Beatty
Journal: Cancer Research
Cancer Res (1985) 45 (11_Part_2): 5700–5706.
Published: 01 November 1985
View article titled, High-Specific-Activity <sup>111</sup>In-labeled Anticarcinoembryonic Antigen Monoconal Antibody: Biodistribution and Imaging in Nude Mice Bearing Human Colon Cancer Xenografts
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Journal Articles

Correspondence re: M. I. Bemhard, K. M. Hwang, K. A. Foon, A. M. Keenan, R. M. Kessler, J. M. Frincke, D. J. Tallam, M. G. Hanna, Jr., L. Peters, and R. K. Oldham. Localization of 111In- and 125I-labeled Monoclonal Antibody in Guinea Pigs Bearing Line 10 Hepatocarcinoma Tumors. Cancer Res., 43: 4429–4433, 1983: The Importance of Traditional Methods of Measuring Tracer Biodistributions

Lawrence E. Williams
Journal: Cancer Research
Cancer Res (1984) 44 (6): 2731.
Published: 01 June 1984
View article titled, Correspondence re: M. I. Bemhard, K. M. Hwang, K. A. Foon, A. M. Keenan, R. M. Kessler, J. M. Frincke, D. J. Tallam, M. G. Hanna, Jr., L. Peters, and R. K. Oldham. Localization of <sup>111</sup>In- and <sup>125</sup>I-labeled Monoclonal Antibody in Guinea Pigs Bearing Line 10 Hepatocarcinoma Tumors. Cancer Res., <em>43:</em> 4429–4433, 1983: <subtitle>The Importance of Traditional Methods of Measuring Tracer Biodistributions</subtitle>
Open the PDF for Correspondence re: M. I. Bemhard, K. M. Hwang, K. A. Foon, A. M. Keenan, R. M. Kessler, J. M. Frincke, D. J. Tallam, M. G. Hanna, Jr., L. Peters, and R. K. Oldham. Localization of <sup>111</sup>In- and <sup>125</sup>I-labeled Monoclonal Antibody in Guinea Pigs Bearing Line 10 Hepatocarcinoma Tumors. Cancer Res., <em>43:</em> 4429–4433, 1983: <subtitle>The Importance of Traditional Methods of Measuring Tracer Biodistributions</subtitle> in another window