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Lauri A. Aaltonen
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Journal Articles

Abstract LB-375: The landscape of somatic mutations in uterine adenomyomas

Jaana Tolvanen, Hanna-Riikka Heinonen, Nanna Sarvilinna, Jari Sjöberg, Oskari Heikinheimo, Annukka Pasanen, Ralf Bützow, Lauri A. Aaltonen, Netta Mäkinen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-375.
https://doi.org/10.1158/1538-7445.AM2018-LB-375
Published: 01 July 2018
View article titled, Abstract LB-375: The landscape of somatic mutations in uterine adenomyomas
Journal Articles

Abstract LB-382: Identification of predisposing genes for small bowel adenocarcinoma by exome sequencing

Ulrika A. Hänninen, Riku Katainen, Tomas Tanskanen, Jiri Hamberg, Ari Ristimäki, Eero Pukkala, Minna Taipale, Jukka-Pekka Mecklin, Mervi Aavikko, Linda M. Forsström, Esa Pitkänen, Netta Mäkinen, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-382.
https://doi.org/10.1158/1538-7445.AM2018-LB-382
Published: 01 July 2018
View article titled, Abstract LB-382: Identification of predisposing genes for small bowel adenocarcinoma by exome sequencing
Journal Articles

Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer

Johanna Kondelin, Alexandra E. Gylfe, Sofie Lundgren, Tomas Tanskanen, Jiri Hamberg, Mervi Aavikko, Kimmo Palin, Heikki Ristolainen, Riku Katainen, Eevi Kaasinen, Minna Taipale, Jussi Taipale, Laura Renkonen-Sinisalo, Heikki Järvinen, Jan Böhm, Jukka-Pekka Mecklin, Pia Vahteristo, Sari Tuupanen, Lauri A. Aaltonen, Esa Pitkänen
Journal: Cancer Research
Cancer Res (2017) 77 (15): 4078–4088.
https://doi.org/10.1158/0008-5472.CAN-17-0682
Published: 01 August 2017
View article titled, Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer
Open the PDF for Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2461: Molecular classification and clinical characterization of a large uterine leiomyoma patient cohort

Netta Mäkinen, Hanna-Riikka Heinonen, Annukka Pasanen, Jaana Tolvanen, Simona Bramante, Miika Mehine, Jari Sjöberg, Oskari Heikinheimo, Ralf Bützow, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2461.
https://doi.org/10.1158/1538-7445.AM2017-2461
Published: 01 July 2017
View article titled, Abstract 2461: Molecular classification and clinical characterization of a large uterine leiomyoma patient cohort
Journal Articles

Abstract 4381: The mobile genome of colorectal cancer: Characterization of retrotransposon insertions in 202 colorectal cancer whole genomes

Tatiana Cajuso, Päivi Sulo, Riku Katainen, Ulrika Hänninen, Tomas Tanskanen, Johanna Kondelin, Jiri Hamberg, Niko Välimäki, Kimmo Palin, Outi Kilpivaara, Esa Pitkänen, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4381.
https://doi.org/10.1158/1538-7445.AM2017-4381
Published: 01 July 2017
View article titled, Abstract 4381: The mobile genome of colorectal cancer: Characterization of retrotransposon insertions in 202 colorectal cancer whole genomes
Journal Articles

Abstract 4379: Somatic exomic landscape of small intestinal adenocarcinomas

Ulrika A. Hänninen, Riku Katainen, Jiri Hamberg, Jukka-Pekka Mecklin, Linda Forsström, Esa Pitkänen, Netta Mäkinen, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4379.
https://doi.org/10.1158/1538-7445.AM2017-4379
Published: 01 July 2017
View article titled, Abstract 4379: Somatic exomic landscape of small intestinal adenocarcinomas
Journal Articles

Abstract 1457: Somatic biallelic inactivation of fumarate hydratase (FH) in uterine leiomyomas

Jaana Tolvanen, Netta Mäkinen, Hanna-Riikka Heinonen, Simona Bramante, Miika Mehine, Nanna Sarvilinna, Jari Sjöberg, Oskari Heikinheimo, Annukka Pasanen, Ralf Bützow, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1457.
https://doi.org/10.1158/1538-7445.AM2017-1457
Published: 01 July 2017
View article titled, Abstract 1457: Somatic biallelic inactivation of <em>fumarate hydratase</em> (<em>FH</em>) in uterine leiomyomas
Journal Articles

Abstract 1440: Germline loss-of-function alleles in Finnish colorectal cancer patients

Tomas Tanskanen, Ulrika Hänninen, Tatiana Cajuso, Johanna Kondelin, Riku Katainen, Jiri Hamberg, Niko Välimäki, Esa Pitkänen, Kimmo Palin, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1440.
https://doi.org/10.1158/1538-7445.AM2017-1440
Published: 01 July 2017
View article titled, Abstract 1440: Germline loss-of-function alleles in Finnish colorectal cancer patients
Journal Articles

Abstract 4435: Genome-scale DNA methylation changes delineate uterine leiomyoma subgroups

Eevi Kaasinen, Amjad Alkodsi, Miika Mehine, Hanna-Riikka Heinonen, Netta Mäkinen, Mervi Aavikko, Kati Kampjärvi, Minna Taipale, Pia Vahteristo, Rainer Lehtonen, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4435.
https://doi.org/10.1158/1538-7445.AM2016-4435
Published: 15 July 2016
View article titled, Abstract 4435: Genome-scale DNA methylation changes delineate uterine leiomyoma subgroups
Journal Articles

Abstract 171: Comparative genomic analyses of synchronous colorectal cancers by exome sequencing

Ulrika A. Hänninen, Tomas Tanskanen, Riku Katainen, Jan Böhm, Minna Taipale, Jussi Taipale, Jukka-Pekka Mecklin, Netta Mäkinen, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 171.
https://doi.org/10.1158/1538-7445.AM2016-171
Published: 15 July 2016
View article titled, Abstract 171: Comparative genomic analyses of synchronous colorectal cancers by exome sequencing
Journal Articles

Abstract 5281: Fast and scalable software for comparative variant analysis and visualization of massive next-generation sequencing data

Riku Katainen, Veli Mäkinen, Lauri A. Aaltonen, Esa Pitkänen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5281.
https://doi.org/10.1158/1538-7445.AM2016-5281
Published: 15 July 2016
View article titled, Abstract 5281: Fast and scalable software for comparative variant analysis and visualization of massive next-generation sequencing data
Journal Articles

Abstract 4800: Identification of candidate predisposition genes for familial uterine leiomyomas

Hanna-Riikka Heinonen, Outi Uimari, Jaana Tolvanen, Markku Ryynänen, Lauri A. Aaltonen, Pia Vahteristo
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4800.
https://doi.org/10.1158/1538-7445.AM2015-4800
Published: 01 August 2015
View article titled, Abstract 4800: Identification of candidate predisposition genes for familial uterine leiomyomas
Journal Articles

Abstract 2744: Familial multiple metastatic small intestine neuroendocrine tumors: searching for genetic susceptibility

Mervi Aavikko, Eevi Kaasinen, Iikki Donner, Kaisa Lehti, Erika Gucciardo, Bideep Shrestha, Jukka-Pekka Mecklin, Järnhult Johannes, Kalle Landerholm, Eero Pukkala, Camilla Schalin-Jäntti, Ari Ristimäki, Pia Vahteristo, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2744.
https://doi.org/10.1158/1538-7445.AM2015-2744
Published: 01 August 2015
View article titled, Abstract 2744: Familial multiple metastatic small intestine neuroendocrine tumors: searching for genetic susceptibility
Journal Articles

Abstract 1079: Transcriptional profiling reveals uterine leiomyoma subtypes with distinct pathways and biomarkers of tumorigenesis

Miika Mehine, Eevi Kaasinen, Esa Pitkänen, Nanna Sarvilinna, Hanna-Riikka Heinonen, Netta Mäkinen, Jari Sjöberg, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1079.
https://doi.org/10.1158/1538-7445.AM2015-1079
Published: 01 August 2015
View article titled, Abstract 1079: Transcriptional profiling reveals uterine leiomyoma subtypes with distinct pathways and biomarkers of tumorigenesis
Journal Articles

Abstract 2176: Joint structural variant analysis of colorectal cancer whole genome sequencing data

Esa Pitkänen, Tatiana Cajuso, Riku Katainen, Sofie Lundgren, Sari Tuupanen, Outi Kilpivaara, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2176.
https://doi.org/10.1158/1538-7445.AM2015-2176
Published: 01 August 2015
View article titled, Abstract 2176: Joint structural variant analysis of colorectal cancer whole genome sequencing data
Journal Articles

Abstract 3514: MED12 and FH mutations in HLRCC associated uterine leiomyomas

Kati Kämpjärvi, Netta Mäkinen, Miika Mehine, Jaana Tolvanen, Tuomas Heikkinen, Ralf Bützow, Lauri A. Aaltonen, Pia Vahteristo
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3514.
https://doi.org/10.1158/1538-7445.AM2014-3514
Published: 01 October 2014
View article titled, Abstract 3514: MED12 and FH mutations in HLRCC associated uterine leiomyomas
Journal Articles

Abstract 5193: Novel candidate oncogenes with mutation hot spots in microsatellite unstable colorectal cancer

Alexandra E. Gylfe, Sari Tuupanen, Ulrika Hänninen, Johanna Kondelin, Heikki Ristolainen, Riku Katainen, Esa Pitkänen, Minna Taipale, Jussi Taipale, Claus Lindbjerg Andersen, Laura Renkonen-Sinisalo, Heikki Järvinen, Jan Böhm, Jukka-Pekka Mecklin, Pia Vahteristo, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5193.
https://doi.org/10.1158/1538-7445.AM2014-5193
Published: 01 October 2014
View article titled, Abstract 5193: Novel candidate oncogenes with mutation hot spots in microsatellite unstable colorectal cancer
Journal Articles

Abstract 2401: Identification of new target genes in microsatellite unstable colorectal cancer by exome sequencing

Johanna Kondelin, Esa Pitkänen, Alexandra E. Gylfe, Kimmo Palin, Heikki Ristolainen, Riku Katainen, Eevi Kaasinen, Minna Taipale, Jussi Taipale, Laura Renkonen-Sinisalo, Heikki Järvinen, Jan Böhm, Jukka-Pekka Mecklin, Pia Vahteristo, Sari Tuupanen, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2401.
https://doi.org/10.1158/1538-7445.AM2014-2401
Published: 01 October 2014
View article titled, Abstract 2401: Identification of new target genes in microsatellite unstable colorectal cancer by exome sequencing
Journal Articles

Lessons from Functional Analysis of Genome-Wide Association Studies

Inderpreet Sur, Sari Tuupanen, Thomas Whitington, Lauri A. Aaltonen, Jussi Taipale
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (14): 4180–4184.
https://doi.org/10.1158/0008-5472.CAN-13-0789
Published: 15 July 2013
View article titled, Lessons from Functional Analysis of Genome-Wide Association Studies
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Journal Articles

Abstract 3156: New candidate oncogenes discovered in microsatellite unstable colorectal cancer.

Alexandra E. Gylfe, Johanna Kondelin, Mikko Turunen, Heikki Ristolainen, Riku Katainen, Esa Pitkänen, Eevi Kaasinen, Ville Rantanen, Tomas Tanskanen, Heli J. Lehtonen, Kimmo Palin, Minna Taipale, Jussi Taipale, Laura Renkonen-Sinisalo, Heikki Järvinen, Jan Böhm, Jukka-Pekka Mecklin, Ari Ristimäki, Sari Tuupanen, Auli Karhu, Outi Kilpivaara, Pia Vahteristo, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3156.
https://doi.org/10.1158/1538-7445.AM2013-3156
Published: 15 April 2013
View article titled, Abstract 3156: New candidate oncogenes discovered in microsatellite unstable colorectal cancer.