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Laura S. Schmidt
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Journal Articles

Abstract 133: Rewinding the tape of life: somatic profiling in Von Hippel-Lindau (VHL) disease reveals evolutionary contingency and constraints

Scott T. Shepherd, Alex Coulton, Cathy D. Vocke, Chris J. Ricketts, Mark Ball, Fiona Byrne, Yuliia Dovga, Annika Fendler, Barber Taja, Olga O'Neill, Lina Gerontogianni, Gavin Kelly, Laura S. Schmidt, Daniel R. Crooks, Kirstin Choo, Rabindra Gautam, Zoe Blake, Krista Reynolds, Kevin Litchfield, Maria Merino, Marston W. Linehan, Samra Turajlic
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 133.
https://doi.org/10.1158/1538-7445.AM2023-133
Published: 04 April 2023
View article titled, Abstract 133: Rewinding the tape of life: somatic profiling in Von Hippel-Lindau (VHL) disease reveals evolutionary contingency and constraints
Journal Articles

Abstract 4708: Comprehensive analysis of 71 VHL germline deletions and rearrangements

Cathy D. Vocke, Christopher J. Ricketts, Laura S. Schmidt, Mark W. Ball, James Peterson, Lindsay A. Middelton, W Marston Linehan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4708.
https://doi.org/10.1158/1538-7445.AM2020-4708
Published: 15 August 2020
View article titled, Abstract 4708: Comprehensive analysis of 71 <em>VHL</em> germline deletions and rearrangements
Journal Articles

Abstract 4719: Novel germline variants in hereditary renal cell carcinoma genes elucidated by whole genome sequencing

Cathy D. Vocke, Christopher J. Ricketts, Daniel R. Crooks, Martin Lang, Laura S. Schmidt, Mayank Tandon, Bao Tran, Christina Fitzsimmons, Pedro J. Batista, Mark W. Ball, W. Marston Linehan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4719.
https://doi.org/10.1158/1538-7445.AM2020-4719
Published: 15 August 2020
View article titled, Abstract 4719: Novel germline variants in hereditary renal cell carcinoma genes elucidated by whole genome sequencing
Journal Articles

Abstract 1244: BHD-associated kidney cancer exhibits unique molecular characteristics and a wide variety of mutations in chromatin remodeling genes

Ryosuke Jikuya, Mitsuko Furuya, Masaya Baba, Hiroyuki Aburatani, Adam R. Metwalli, Laura S. Schmidt, W. Marston Linehan, Masahiro Yao, Hisashi Hasumi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1244.
https://doi.org/10.1158/1538-7445.AM2018-1244
Published: 01 July 2018
View article titled, Abstract 1244: BHD-associated kidney cancer exhibits unique molecular characteristics and a wide variety of mutations in chromatin remodeling genes
Journal Articles

Abstract 1400: Using tumor spheroids to evaluate the efficacy of EZH2 inhibitors in clear cell renal cell carcinoma (ccRCC)

Darmood Wei, Youfeng Yang, Christopher J. Ricketts, Carole Sourbier, Laura S. Schmidt, William M. Linehan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1400.
https://doi.org/10.1158/1538-7445.AM2017-1400
Published: 01 July 2017
View article titled, Abstract 1400: Using tumor spheroids to evaluate the efficacy of EZH2 inhibitors in clear cell renal cell carcinoma (ccRCC)
Journal Articles

Abstract 3527: Clarification of the molecular mechanism for cancer development in Xp11.2 translocation renal cell carcinoma

Masaya Baba, Ying Huang, Takanobu Motoshima, Hisashi Hasumi, Yukiko Hasumi, Mitsuko Furuya, Yoji Nagashima, Masahiro Yao, Yuichi Oike, Tomomi Kamba, Laura S. Schmidt, W. Marston Linehan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3527.
https://doi.org/10.1158/1538-7445.AM2017-3527
Published: 01 July 2017
View article titled, Abstract 3527: Clarification of the molecular mechanism for cancer development in Xp11.2 translocation renal cell carcinoma
Journal Articles

Abstract 4707: Investigating the role of EZH2 as a therapeutic target in clear cell renal cell carcinoma (ccRCC)

Darmood Wei, Christopher J. Ricketts, Laura S. Schmidt, Youfeng Yang, Cathy D. Vocke, William M. Linehan
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4707.
https://doi.org/10.1158/1538-7445.AM2016-4707
Published: 15 July 2016
View article titled, Abstract 4707: Investigating the role of EZH2 as a therapeutic target in clear cell renal cell carcinoma (ccRCC)
Journal Articles

Abstract LB-107: Mitochondrial DNA mutations are diagnostic markers of renal oncocytomas.

Martin Lang, Cathy D. Vocke, Maria J. Merino, Laura S. Schmidt, Marston W. Linehan
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-107.
https://doi.org/10.1158/1538-7445.AM2013-LB-107
Published: 15 April 2013
View article titled, Abstract LB-107: Mitochondrial DNA mutations are diagnostic markers of renal oncocytomas.
Journal Articles

Mitotic arrest and cellular senescence by the acute inactivation of the VHL gene

Seung-Beom Hong, Berton Zbar, Laura S. Schmidt
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1048.
Published: 01 May 2005
View article titled, Mitotic arrest and cellular senescence by the acute inactivation of the <em>VHL</em> gene
Journal Articles

Conditional inactivation of the VHL gene during mouse embryo development

Seung-Beom Hong, Mutsuo Furihata, Berton Zbar, Laura S. Schmidt
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1178.
Published: 01 April 2004
View article titled, Conditional inactivation of the <em>VHL</em> gene during mouse embryo development
Journal Articles

Expression of Birt-Hogg-Dubé gene mRNA in normal and neoplastic human tissues

Michelle B. Warren, Carlos A. Torres-Cabalas, Maria L. Turner, Maria J. Merino, Vera Matrosova, Michael L. Nickerson, W. Marston Linehan, Berton Zbar, Laura S. Schmidt
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 988.
Published: 01 April 2004
View article titled, Expression of Birt-Hogg-Dubé gene mRNA in normal and neoplastic human tissues
Journal Articles

Studies on the Birt-Hogg-Dube gene product, the tumor suppressor Folliculin

Michael L. Nickerson, Masaya Baba, Wei Zhen, Michelle B. Warren, Dominic Esposito, Nirmala Sharma, Laura S. Schmidt, Bert Zbar
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 970.
Published: 01 April 2004
View article titled, Studies on the Birt-Hogg-Dube gene product, the tumor suppressor Folliculin
Journal Articles

Familial renal carcinoma (FRC): Recruitment of families with multiple members affected with renal cancer

Berton Zbar, Laura S. Schmidt, Shyla Hale, Gregory W. Maher, Maria J. Merino, W. Marston Linehan
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 304.
Published: 01 April 2004
View article titled, Familial renal carcinoma (FRC): Recruitment of families with multiple members affected with renal cancer
Journal Articles

Hepatic Vascular Tumors, Angiectasis in Multiple Organs, and Impaired Spermatogenesis in Mice with Conditional Inactivation of the VHL Gene

Wenbin Ma, Lino Tessarollo, Seung-Beom Hong, Masaya Baba, Eileen Southon, Timothy C. Back, Sally Spence, Corrinne G. Lobe, Nirmala Sharma, Gregory W. Maher, Svetlana Pack, Alexander O. Vortmeyer, Chuanfa Guo, Berton Zbar, Laura S. Schmidt
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5320–5328.
Published: 18 September 2003
View article titled, Hepatic Vascular Tumors, Angiectasis in Multiple Organs, and Impaired Spermatogenesis in Mice with Conditional Inactivation of the <em>VHL</em> Gene
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Includes: Supplementary data