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Laura P. Stabile
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Journal Articles

Abstract 3391: Effects of repeated psychological stress on NNK-induced lung cancer development in young female mice

Frank Jenkins, Laura P. Stabile, Jessie R. Nedrow, Kathryn Day, Joseph D. Latoche, Patrick M. Tarwater, Jessica Manculich, Dana H. Bovbjerg
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3391.
https://doi.org/10.1158/1538-7445.AM2024-3391
Published: 22 March 2024
View article titled, Abstract 3391: Effects of repeated psychological stress on NNK-induced lung cancer development in young female mice
Journal Articles

Abstract 4743: Targeting a novel TWIST1-Hexokinase II pathway to overcome MET TKI resistance in NSCLC

Purva H. Rumde, Kasey R. Cargill, Vinod Kumar, Princey Devadassan, Jason Chen, Leviticus McGraw-Sapp, Xiaxuan Wu, Sanja Dacic, Riyue Bao, Bharathri Sivakama, Eric S. Goetzman, Sameer Agnihotri, Steven J. Mullett, Stacey G. Wendell, Laura P. Stabile, Timothy F. Burns
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4743.
https://doi.org/10.1158/1538-7445.AM2024-4743
Published: 22 March 2024
View article titled, Abstract 4743: Targeting a novel TWIST1-Hexokinase II pathway to overcome MET TKI resistance in NSCLC
Journal Articles

Abstract 777: Super-resolution imaging of heterochromatin structure detects early events in lung cancer

Laura P. Stabile, Xuejiao Sun, Jianquan Xu, Beatriz Kanterewicz, David O. Wilson, Sanja Dacic, Lora H. Rigatti, Brenda Diergaarde, Yang Liu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 777.
https://doi.org/10.1158/1538-7445.AM2023-777
Published: 04 April 2023
View article titled, Abstract 777: Super-resolution imaging of heterochromatin structure detects early events in lung cancer
Journal Articles

Abstract 3853: The TWIST1-p27 signaling pathway is a critical determinant of MET TKI cell cycle arrest and resistance in MET altered non-small cell lung cancer

Vinod Kumar, Zachary A. Yochum, Princey Devadassan, Eric Huang, Ethan Miller, Vasavi Ayyala, Purva H. Rumde, Roja Baruwal, James O’Brien, Laura P. Stabile, Timothy F. Burns
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3853.
https://doi.org/10.1158/1538-7445.AM2023-3853
Published: 04 April 2023
View article titled, Abstract 3853: The TWIST1-p27 signaling pathway is a critical determinant of MET TKI cell cycle arrest and resistance in <em>MET</em> altered non-small cell lung cancer
Journal Articles

Abstract 6042: Targeting metabolic vulnerabilities in MET-driven lung cancer brain metastases

Kasey R. Cargill, Sanja Dacic, Riyue Bao, Bharathri Sivakama, Eric S. Goetzman, Steven J. Mullett, Stacy G. Wendell, Sameer Agnihotri, Laura P. Stabile, Timothy F. Burns
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6042.
https://doi.org/10.1158/1538-7445.AM2023-6042
Published: 04 April 2023
View article titled, Abstract 6042: Targeting metabolic vulnerabilities in MET-driven lung cancer brain metastases
Journal Articles

Abstract 1091: TWIST1 inhibition overcomes resistance to tyrosine kinase inhibitors in MET driven non-small cell lung cancer

Vinod Kumar, Zachary A. Yochum, Princey Devadassan, Eric Huang, Ethan Miller, Vasavi Ayyala, Laura P. Stabile, Timothy F. Burns, Purva H. Rumde
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1091.
https://doi.org/10.1158/1538-7445.AM2022-1091
Published: 15 June 2022
View article titled, Abstract 1091: TWIST1 inhibition overcomes resistance to tyrosine kinase inhibitors in MET driven non-small cell lung cancer
Journal Articles

Abstract 2218: MET alterations are enriched in lung adenocarcinoma brain metastases and define a distinct molecular and transcriptomic subtype

Timothy F. Burns, Sanja Dacic, Maria A. Velez, Ashwin Somasundaram, Saveri Bhattacharya, Anish Chakka, Zachary A. Yochum, Jingxiao Jin, Ethan Miller, Brenda F. Kurland, Riyue Bao, Danielle P. Normolle, Sameer Agnihotri, Uma R. Chandran, Laura P. Stabile
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2218.
https://doi.org/10.1158/1538-7445.AM2021-2218
Published: 01 July 2021
View article titled, Abstract 2218: MET alterations are enriched in lung adenocarcinoma brain metastases and define a distinct molecular and transcriptomic subtype
Journal Articles

Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration

Manjulata Singh, Xiao-Jun Tian, Vera S. Donnenberg, Alan M. Watson, JingYu Zhang, Laura P. Stabile, Simon C. Watkins, Jianhua Xing, Shilpa Sant
Journal: Cancer Research
Cancer Res (2019) 79 (11): 2962–2977.
https://doi.org/10.1158/0008-5472.CAN-18-3151
Published: 03 June 2019
View article titled, Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration
Open the PDF for Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 5889: TWIST1 is a key mediator of HGF-MET-driven resistance to targeted therapies in EGFR mutant and MET-driven lung cancer

Zachary A. Yochum, Suman Chatterjee, Eric H. Huang, Deena M. Maurer, Myriam A. Attar, Sanja Dacic, Laura P. Stabile, Timothy F. Burns
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5889.
https://doi.org/10.1158/1538-7445.AM2018-5889
Published: 01 July 2018
View article titled, Abstract 5889: TWIST1 is a key mediator of HGF-MET-driven resistance to targeted therapies in <em>EGFR</em> mutant and MET-driven lung cancer
Journal Articles

Abstract 1005: Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancer

Laura P. Stabile, Natalie J. Rothenberger, Mariya Farooqui, Sanja Dacic, Jill M. Siegfried
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1005.
https://doi.org/10.1158/1538-7445.AM2017-1005
Published: 01 July 2017
View article titled, Abstract 1005: Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancer
Journal Articles

Abstract CT119: Phase II study of dasatinib in combination with cetuximab in recurrent/metastatic head and neck squamous cell carcinoma

Laura P. Stabile, Ann Marie Egloff, Pei Zhou, William E. Gooding, Jennifer R. Grandis, Julie E. Bauman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): CT119.
https://doi.org/10.1158/1538-7445.AM2016-CT119
Published: 15 July 2016
View article titled, Abstract CT119: Phase II study of dasatinib in combination with cetuximab in recurrent/metastatic head and neck squamous cell carcinoma
Journal Articles

Abstract LB-079: Effect of diet-induced obesity on tobacco carcinogen-induced lung carcinogenesis in mice

Brenda Diergaarde, Beatriz Kanterewicz, Mary E. Rothstein, Autumn Gaither-Davis, Shira R. Abberbock, Brenda F. Kurland, Laura P. Stabile
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-079.
https://doi.org/10.1158/1538-7445.AM2016-LB-079
Published: 15 July 2016
View article titled, Abstract LB-079: Effect of diet-induced obesity on tobacco carcinogen-induced lung carcinogenesis in mice
Journal Articles

Abstract 2181: Differential expression of genes related to autoimmunity and metabolism in Stage I NSCLC from patients with COPD

Jill M. Siegfried, Kan Shang, Cavan Reilly, Laura P. Stabile
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2181.
https://doi.org/10.1158/1538-7445.AM2015-2181
Published: 01 August 2015
View article titled, Abstract 2181: Differential expression of genes related to autoimmunity and metabolism in Stage I NSCLC from patients with COPD
Journal Articles

Abstract 1861: Estrogen modulation of fibroblast growth factor signaling in non-small cell lung cancer

Laura P. Stabile, Natalie J. Rothenberger, Marjorie Romkes, Lisa Koodie, Mariya Farooqui, Sanja Dacic, Jill M. Siegfried
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1861.
https://doi.org/10.1158/1538-7445.AM2015-1861
Published: 01 August 2015
View article titled, Abstract 1861: Estrogen modulation of fibroblast growth factor signaling in non-small cell lung cancer
Journal Articles

Abstract 608: Targeting the estrogen pathway in a male mouse model of lung tumor prevention

Laura P. Stabile, Mary E. Rothstein, Brenda F. Kurland, Diana Cunningham, Matthew Orlowski, Jill M. Siegfried
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 608.
https://doi.org/10.1158/1538-7445.AM2014-608
Published: 01 October 2014
View article titled, Abstract 608: Targeting the estrogen pathway in a male mouse model of lung tumor prevention
Journal Articles

Abstract 4664: Result of TORI L-03, a randomized, multicenter phase II clinical trial of erlotinib (E) or E + fulvestrant (F) in previously treated advanced non-small cell lung cancer (NSCLC).

Edward B. Garon, Jill M. Siegfried, Steven M. Dubinett, Robert M. Elashoff, David J. Park, Rupesh J. Parikh, Ravi Patel, Eddie H. Hu, Karen L. Reckamp, Brad Adams, Diego Martinez, He-Jing Wang, Fairooz Kabbinavar, Sanja Dacic, Meghan Brennan, Isett Laux, Diana C. Marquez-Garban, Laura P. Stabile, Dennis J. Slamon, Richard J. Pietras
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4664.
https://doi.org/10.1158/1538-7445.AM2013-4664
Published: 15 April 2013
View article titled, Abstract 4664: Result of TORI L-03, a randomized, multicenter phase II clinical trial of erlotinib (E) or E + fulvestrant (F) in previously treated advanced non-small cell lung cancer (NSCLC).
Journal Articles

Abstract 2026: Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model with heightened HGF signaling in the airways.

Laura P. Stabile, Mary E. Rothstein, Christopher T. Gubish, Nathan Lee, Diana E. Cunningham, Jill M. Siegfried
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2026.
https://doi.org/10.1158/1538-7445.AM2013-2026
Published: 15 April 2013
View article titled, Abstract 2026: Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model with heightened HGF signaling in the airways.
Journal Articles

Abstract 3864: Biological basis of pan-ErbB receptor targeting for malignant melanoma treatment

Yuen Keng Ng, Laura P. Stabile, Salina M. Torres, Kathryn M. Supko, Jia-Ying Lee, Jonhan Ho, Marianne Berwick, Jill M. Siegfried
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3864.
https://doi.org/10.1158/1538-7445.AM2012-3864
Published: 15 April 2012
View article titled, Abstract 3864: Biological basis of pan-ErbB receptor targeting for malignant melanoma treatment
Journal Articles

Abstract LB-180: Prevention of NNK-induced lung cancer in mice by anti-estrogen therapy

Jill M. Siegfried, Mary E. Rothstein, Diana Lenzner, Christopher T. Gubish, Stephanie R. Land, Laura P. Stabile
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-180.
https://doi.org/10.1158/1538-7445.AM10-LB-180
Published: 15 April 2010
View article titled, Abstract LB-180: Prevention of NNK-induced lung cancer in mice by anti-estrogen therapy
Journal Articles

Abstract 3483: Combining the multi-targeted tyrosine kinase inhibitor, vandetanib, with fulvestrant results in enhanced anti-tumorigenic effects for lung cancer

Christopher T. Gubish, Laura P. Stabile, Christina Davis, Mary E. Rothstein, Jill M. Siegfried
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3483.
https://doi.org/10.1158/1538-7445.AM10-3483
Published: 15 April 2010
View article titled, Abstract 3483: Combining the multi-targeted tyrosine kinase inhibitor, vandetanib, with fulvestrant results in enhanced anti-tumorigenic effects for lung cancer