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Laura McDonald
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Journal Articles

RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical Outcome

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Nicholas Rooney, Susan M. Mason, Laura McDonald, J. Henry M. Däbritz, Kirsteen J. Campbell, Ann Hedley, Steven Howard, Dimitris Athineos, Colin Nixon, William Clark, Joshua D.G. Leach, Owen J. Sansom, Joanne Edwards, Ewan R. Cameron, Karen Blyth
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (11): 2325–2339.
https://doi.org/10.1158/0008-5472.CAN-19-3870
Published: 02 June 2020
View articletitled, RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical Outcome
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Includes: Supplementary data
Journal Articles

A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma

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Joanna L. Birch, Karen Strathdee, Lesley Gilmour, Antoine Vallatos, Laura McDonald, Ariadni Kouzeli, Richa Vasan, Abdulrahman Hussain Qaisi, Daniel R. Croft, Diane Crighton, Kathryn Gill, Christopher H. Gray, Jennifer Konczal, Mokdad Mezna, Duncan McArthur, Alexander W. Schüttelkopf, Patricia McConnell, Mairi Sime, William M. Holmes, Justin Bower, Heather J. McKinnon, Martin Drysdale, Michael F. Olson, Anthony J. Chalmers
Journal: Cancer Research
Cancer Res (2018) 78 (22): 6509–6522.
https://doi.org/10.1158/0008-5472.CAN-18-1697
Published: 15 November 2018
View articletitled, A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma
Open the PDF for A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 1933: A novel small molecule inhibitor of MRCK shows utility in blocking radiation induced invasion of glioblastoma cells in vitro and in vivo

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Heather J. McKinnon, Joanna Birch, Laura McDonald, Mairi Sime, Daniel Croft, Diane Crighton, Martin Drysdale, Lesley Gilmore, Christopher Gray, Jennifer Konczal, Duncan McArthur, Patricia McConnell, Mokdad Mezna, Alexander Schuettelkopf, Karen Strathdee, Justin Bower, Michael F. Olson, Anthony J. Chalmers
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1933.
https://doi.org/10.1158/1538-7445.AM2018-1933
Published: 01 July 2018
View articletitled, Abstract 1933: A novel small molecule inhibitor of MRCK shows utility in blocking radiation induced invasion of glioblastoma cells in vitro and in vivo
Journal Articles

Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer

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Mathieu Unbekandt, Simone Belshaw, Justin Bower, Maeve Clarke, Jacqueline Cordes, Diane Crighton, Daniel R. Croft, Martin J. Drysdale, Mathew J. Garnett, Kathryn Gill, Christopher Gray, David A. Greenhalgh, James A.M. Hall, Jennifer Konczal, Sergio Lilla, Duncan McArthur, Patricia McConnell, Laura McDonald, Lynn McGarry, Heather McKinnon, Carol McMenemy, Mokdad Mezna, Nicolas A. Morrice, June Munro, Gregory Naylor, Nicola Rath, Alexander W. Schüttelkopf, Mairi Sime, Michael F. Olson
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (8): 2096–2114.
https://doi.org/10.1158/0008-5472.CAN-17-2870
Published: 12 April 2018
View articletitled, Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer
Open the PDF for Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract LB-228: Identifying small molecule inhibitors of Fascin 1 using fragment-based drug discovery

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Daniel Croft, Stuart Francis, Justin Bower, Andrea Gohlke, Gillian Goodwin, Christopher Gray, Jennifer Konczal, Sophie Macconnachie, Patricia McConnell, Laura McDonald, Heather McKinnon, Mokdad Mezna, Charles Parry, Nikki Paul, Angelo Pugliese, Alexander Schuettelkopf, Laura Machesky, Martin Drysdale
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-228.
https://doi.org/10.1158/1538-7445.AM2017-LB-228
Published: 01 July 2017
View articletitled, Abstract LB-228: Identifying small molecule inhibitors of Fascin 1 using fragment-based drug discovery