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Larry Norton
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Journal Articles

Abstract 2398: Pregnancy-specific glycoproteins in tumors are strong predictors of outcome in female lung adenocarcinoma patients

Free
Jung Hun Oh, Gabrielle Rizzuto, Rena Elkin, Corey Weistuch, Larry Norton, Gabriela Dveksler, Joseph O. Deasy
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2398.
https://doi.org/10.1158/1538-7445.AM2025-2398
Published: 21 April 2025
View articletitled, Abstract 2398: Pregnancy-specific glycoproteins in tumors are strong predictors of outcome in female lung adenocarcinoma patients
Journal Articles

Abstract PO5-19-07: A Single Arm Phase 2 Study of Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer

Free
Heather McArthur, Elizabeth Comen, Yolanda Bryce, Stephen Solomon, Sangeetha Reddy, Isaac Chan, Baṣak Dogan, Dawn Klemow, Nisha Unni, Jorge Henrique Santos Leal, Cristal Martinez, Reva Basho, Dorothy Park, Philomena McAndrew, Brigid Larkin, David Page, William Mills, Staci Mellinger, Nicole Fredrich, Nicole Moxon, Lynette Currie, Meredith Carter, Melissa Ramos, Stephanie Rice, Sujata Patil, Margaret Gatti-Mays, Larry Norton
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-19-07.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-19-07
Published: 02 May 2024
View articletitled, Abstract PO5-19-07: A Single Arm Phase 2 Study of Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer
Journal Articles

Abstract PO5-26-11: The Breast Cancer Research Foundation Drug Research Collaborative – A unique and innovative model for industry-funded, academically driven research to advance the field of breast cancer

Free
Unnati Jariwala, Dorraya El-Ashry, Judy Garber, Larry Norton
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-26-11.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-26-11
Published: 02 May 2024
View articletitled, Abstract PO5-26-11: The Breast Cancer Research Foundation Drug Research Collaborative – A unique and innovative model for industry-funded, academically driven research to advance the field of breast cancer
Journal Articles

Abstract PO3-14-08: Metaplastic Breast Cancer: Whole Genome Sequencing Analysis and Emerging Therapeutic Targets

Free
Fresia Pareja, Andrea Gazzo, Higinio Dopeso, David Brown, Pier Selenica, Yingjie Zhu, Juan Blanco-Heredia, Laxmi Gusain, Xin Pei, Giacomo Montagna, Nour Abuhadra, Hanna Y Wen, Edi Brogi, Nadeem Riaz, Sarat Chandarlapaty, Maurizio Scaltriti, Larry Norton, Simon Powell, Jorge Reis-Filho, Britta Weigelt
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-14-08.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-14-08
Published: 02 May 2024
View articletitled, Abstract PO3-14-08: Metaplastic Breast Cancer: Whole Genome Sequencing Analysis and Emerging Therapeutic Targets
Journal Articles

Abstract PO1-03-06: Older patients with Early Stage Triple Negative Breast Cancer: The Memorial Sloan Kettering Cancer Center experience

Free
Jasmeet Singh, Diana Lake, West Dente-Ferguson, Yuan Chen, Fiona Erlich, Beatriz Korc-Grodzicki, Mark Robson, Larry Norton, W. Iris Zhi
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-03-06.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-03-06
Published: 02 May 2024
View articletitled, Abstract PO1-03-06: Older patients with Early Stage Triple Negative Breast Cancer: The Memorial Sloan Kettering Cancer Center experience
Journal Articles

Abstract LB208: An intricate connection between canonical Wnt and MAPK/ERK signaling drives the partial hybrid EMT state involving FOXC2/p63 activation leading to cancer stemness and metastasis

Free
Huizhi Liang, Outhiriaradjou Benard, Zuen Ren, Kimita Suyama, Jingli Wang, Anthony Griffen, Hao Wang, Lindsay LeFave, Larry Norton, Rachel B. Hazan
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB208.
https://doi.org/10.1158/1538-7445.AM2024-LB208
Published: 05 April 2024
View articletitled, Abstract LB208: An intricate connection between canonical Wnt and MAPK/ERK signaling drives the partial hybrid EMT state involving FOXC2/p63 activation leading to cancer stemness and metastasis
Journal Articles

Abstract SY34-02: Age-related and organ-specific host mosaicism as a driver of dormant cancer cell awakening

Free
Julio A. Aguirre-Ghiso, Michael Papanicolaou, Pablo Sánchez Vela, Julie Yang, Anton Safonov, Jacqueline Tao, Sebastia Franch Exposito, Vera Tiedje, Erica Dalla, Luis E. Valencia Salazar, Nicole Barth, Merve Sahin, Kevin Chen, Jinae Park, Matthew Wereski, Aishwarya Krishnan, Anthony Martinez Benitez, Ryan Ptashkin, Mark E. Robson, Elisa de Stanchina, Lior Z. Braunstein, Ahmet Zehir, Elizabeth Comen, Larry Norton, Michael Berger, Richard Koche, Pedram Razavi, Ross Levine
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): SY34-02.
https://doi.org/10.1158/1538-7445.AM2024-SY34-02
Published: 05 April 2024
View articletitled, Abstract SY34-02: Age-related and organ-specific host mosaicism as a driver of dormant cancer cell awakening
Journal Articles

Abstract 5367: Deep neural networks using protein-protein network information predict multiple myeloma survival

Free
Jiening Zhu, Jung Hun Oh, Anish K. Simhal, Rena Elkin, Larry Norton, Joseph O. Deasy, Allen R. Tannenbaum
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5367.
https://doi.org/10.1158/1538-7445.AM2023-5367
Published: 04 April 2023
View articletitled, Abstract 5367: Deep neural networks using protein-protein network information predict multiple myeloma survival
Journal Articles

Abstract 6541: Geometry of gene expression network reveals potential novel indicator in Ewing sarcoma

Free
Rena Elkin, Jung Hun Oh, Filemon Dela Cruz, Larry Norton, Joseph O. Deasy, Andrew L. Kung, Allen R. Tannenbaum
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6541.
https://doi.org/10.1158/1538-7445.AM2023-6541
Published: 04 April 2023
View articletitled, Abstract 6541: Geometry of gene expression network reveals potential novel indicator in Ewing sarcoma
Journal Articles

Abstract 1228: TCF1 orchestrates the epithelial/mesenchymal hybrid phenotype in basal breast cancer via upregulation of FOXC2 leading to stemness and metastasis

Free
Huizhi Liang, Outhiriaradjou Benard, Kimita Suyama, Zuen Ren, Hao Wang, Larry Norton, Rachel Hazan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1228.
https://doi.org/10.1158/1538-7445.AM2023-1228
Published: 04 April 2023
View articletitled, Abstract 1228: TCF1 orchestrates the epithelial/mesenchymal hybrid phenotype in basal breast cancer via upregulation of FOXC2 leading to stemness and metastasis
Journal Articles

Abstract 2061: Protein network analysis uncovers a poor-survival subtype in multiple myeloma

Free
Anish K. Simhal, Kylee H. Maclachlan, Rena Elkin, Jiening Zhu, Saad Z. Usmani, Jonathan J. Keats, Larry Norton, Joseph O. Deasy, Jung Hun Oh, Allen Tannenbaum
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2061.
https://doi.org/10.1158/1538-7445.AM2023-2061
Published: 04 April 2023
View articletitled, Abstract 2061: Protein network analysis uncovers a poor-survival subtype in multiple myeloma
Journal Articles

Abstract 6591: A universal atlas of cellular and oncogenic phenotypes

Free
Corey Weistuch, Kevin Murgas, Ken Dill, Larry Norton, Joseph Deasy, Allen Tannenbaum
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6591.
https://doi.org/10.1158/1538-7445.AM2023-6591
Published: 04 April 2023
View articletitled, Abstract 6591: A universal atlas of cellular and oncogenic phenotypes
Journal Articles

Abstract P4-02-01: Efficacy of HER2 ADCs against HER2 inhibitor resistance alterations in the PI3K and MAPK pathways in HER2-positive breast cancer

Free
Emanuela Ferraro, Anton Safonov, Yuan Chen, Charlie White, Antonio Marra, Mehnaj Ahmed, Barbara Acevedo, Chau T Dang, Shanu Modi, David B. Solit, Larry Norton, Mark E. Robson, Jorge Reis-Filho, Sarat Chandarlapaty, Pedram Razavi
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-02-01.
https://doi.org/10.1158/1538-7445.SABCS22-P4-02-01
Published: 01 March 2023
View articletitled, Abstract P4-02-01: Efficacy of HER2 ADCs against HER2 inhibitor resistance alterations in the PI3K and MAPK pathways in HER2-positive breast cancer
Journal Articles

Abstract P4-02-18: Impact of clonal hematopoiesis on disease progression following CDK4/6 inhibitor therapy

Free
Jacqueline Tao, Pablo Sanchez Vela, Anton Safonov, Emanuela Ferraro, Sebastia Franch Exposito, Kamal Menghrajani, Ryan Ptashkin, Elizabeth Comen, Lior Z. Braunstein, Mark E. Robson, Sarat Chandarlapaty, Jorge Reis-Filho, Michael Berger, Ahmet Zehir, Larry Norton, Ross Levine, Pedram Razavi
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-02-18.
https://doi.org/10.1158/1538-7445.SABCS22-P4-02-18
Published: 01 March 2023
View articletitled, Abstract P4-02-18: Impact of clonal hematopoiesis on disease progression following CDK4/6 inhibitor therapy
Journal Articles

Abstract OT2-17-02: The ARETHA Study: A phase 2 randomized control trial of Eribulin with Evexomostat (SDX-7320) or placebo for patients with metastatic triple-negative breast cancer and metabolic dysfunction

Free
Sherry Shen, Anna Whalen, Mark E. Robson, Larry Norton, Tiffany A. Traina, Neil M. Iyengar
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): OT2-17-02.
https://doi.org/10.1158/1538-7445.SABCS22-OT2-17-02
Published: 01 March 2023
View articletitled, Abstract OT2-17-02: The ARETHA Study: A phase 2 randomized control trial of Eribulin with Evexomostat (SDX-7320) or placebo for patients with metastatic triple-negative breast cancer and metabolic dysfunction
Journal Articles

Abstract OT1-19-01: A Single Arm Phase 2 Study of Peri-Operative Checkpoint-Mediated Immune Therapy and Cryoablation in Women with Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer

Free
Heather McArthur, Elizabeth Comen, Yolanda Bryce, Stephen Solomon, Jorge Henrique Santos Leal, Christina DiLauro Abaya, Cristal Martinez, Reva Basho, Dorothy Park, Philomena McAndrew, Brigid Larkin, William Mills, David B. Page, Staci Mellinger, Nicole Fredrich, Nicole Moxon, Sangeetha Reddy, Meredith Carter, Sujata Patil, Larry Norton
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): OT1-19-01.
https://doi.org/10.1158/1538-7445.SABCS22-OT1-19-01
Published: 01 March 2023
View articletitled, Abstract OT1-19-01: A Single Arm Phase 2 Study of Peri-Operative Checkpoint-Mediated Immune Therapy and Cryoablation in Women with Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer
Journal Articles

Abstract 1928: Prediction of neoadjuvant treatment outcomes with multimodal data integration in breast cancer

Free
Pegah Khosravi, Elizabeth J. Sutton, Justin Jee, Timothy Dalfonso, Christopher J. Fong, Doori Rose, Edaise M. Da Silva, Armaan Kohli, David Joon Ho, Mehnaj S. Ahmed, Danny Martinez, Anika Begum, Elizabeth Zakszewski, Andrew Aukerman, Yanis Tazi, Katja Pinker-Domenig, Sarah Eskreis-Winkler, Atif J. Khan, Edi Brogi, Elizabeth Morris, Sarat Chandarlapaty, George Plitas, Simon Powell, Monica Morrow, Larry Norton, Jianjiong Gao, Mark Robson, Hong Zhang, Sohrab Shah, Pedram Razavi, MSK-MIND Consortium
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1928.
https://doi.org/10.1158/1538-7445.AM2022-1928
Published: 15 June 2022
View articletitled, Abstract 1928: Prediction of neoadjuvant treatment outcomes with multimodal data integration in breast cancer
Journal Articles

Abstract 961: TCF7 promotes a mammary cancer-stem-like phenotype leading to metastasis via potentiation of a hybrid epithelial/mesenchymal (E/M) phenotype

Free
Huizhi Liang, Outhiriaradjou Benard, Zuen Ren, Kimita Suyama, Larry Norton, Rachel B. Hazan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 961.
https://doi.org/10.1158/1538-7445.AM2022-961
Published: 15 June 2022
View articletitled, Abstract 961: TCF7 promotes a mammary cancer-stem-like phenotype leading to metastasis via potentiation of a hybrid epithelial/mesenchymal (E/M) phenotype
Journal Articles

Abstract 968: Loss of glutathione peroxidase 2 promotes epithelial to mesenchymal transition and breast cancer metastasis

Free
Zuen Ren, Huizhi Liang, Malindrie Dharmaratne, Miriam Morales-Gallego, Atefeh Taherian Fard, Jessica Mar, Kimita Suyama, Outhiriaradjou Benard, Michael B. Prystowsky, Larry Norton, Rachel B. Hazan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 968.
https://doi.org/10.1158/1538-7445.AM2022-968
Published: 15 June 2022
View articletitled, Abstract 968: Loss of glutathione peroxidase 2 promotes epithelial to mesenchymal transition and breast cancer metastasis
Journal Articles

Abstract GS4-08: Comprehensive genomic profiling of patients with breast cancer identifies germline-somatic interactions mediating therapy resistance

Free
Anton Safonov, Chai Bandlamudi, Paulino Tallón de Lara, Emanuela Ferraro, Fatemeh Derakhshan, Marie Will, Mark Donoghue, Pier Selenica, Joshua Drago, Ezra Rosen, Carlos dos Anjos, Elaine Walsh, Elizabeth A Comen, Mehnaj Ahmed, Barbara Acevedo, Ahmet Zehir, Michael F Berger, David Solit, Larry Norton, Ronglai Shen, Zsofia Stadler, Simon Powell, Jorge S Reis-Filho, Sarat Chandarlapaty, Mark Robson, Pedram Razavi
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): GS4-08.
https://doi.org/10.1158/1538-7445.SABCS21-GS4-08
Published: 15 February 2022
View articletitled, Abstract GS4-08: Comprehensive genomic profiling of patients with breast cancer identifies germline-somatic interactions mediating therapy resistance