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Journal Articles

Abstract LB074: Targeting chromatin remodeling disrupts immune suppression by pathologically activated neutrophils in cancer

Fan Yang, Yi Bao, Lanbo Xiao, Yuanyuan Qiao, Yizhi Cao, Arul M. Chinnaiyan

Cancer Res (2025) 85 (8_Supplement_2): LB074.

https://doi.org/10.1158/1538-7445.AM2025-LB074

Published: 25 April 2025

View articletitled, Abstract LB074: Targeting chromatin remodeling disrupts immune suppression by pathologically activated neutrophils in cancer

Journal Articles

Abstract 3936: CDK12 tumor suppressor function and therapeutic targeting in newly developed mouse models of serous ovarian cancer

Jean Ching-Yi Tien, Yali Zhai, Rong Wu, Yuping Zhang, Yu Chang, Yunhui Cheng, Abigail J. Todd, Christina Wheeler, Shuqin Li, Rahul Mannan, Caleb Cheng, Somnath Somnath Mahapatra, Xuhong Cao, Yuanyuan Qiao, Lanbo Xiao, Marcin Cieslik, Ding Ke, Kathleen R. Cho, Arul M. Chinnaiyan

Cancer Res (2025) 85 (8_Supplement_1): 3936.

https://doi.org/10.1158/1538-7445.AM2025-3936

Published: 21 April 2025

View articletitled, Abstract 3936: CDK12 tumor suppressor function and therapeutic targeting in newly developed mouse models of serous ovarian cancer

Journal Articles

Abstract 6602: Targeting the SWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

Lanbo Xiao, Tongchen He, Olaf Klingbeil, Young Eleanor, Xiaoli Wu, Yuanyuan Qiao, Abhijit Parolia, Sanjana Eyunni, Rahul Mannan, Somnath Mahapatra, NamHoon Kim, Heng Zheng, Fengyun Su, Xuhong Cao, Susanta Samajdar, Murali Ramachandra, Christopher R. Vakoc, Arul M. Chinnaiyan

Cancer Res (2024) 84 (6_Supplement): 6602.

https://doi.org/10.1158/1538-7445.AM2024-6602

Published: 22 March 2024

View articletitled, Abstract 6602: Targeting the SWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

Journal Articles

Abstract PR-007: H3.3K27M diffuse midline gliomas are sensitive to SWI/SNF chromatin remodeler degradation

Mateus Mota, Stefan Sweha, Matt Pun, Siva Kumar Natarajan, Yujie Ding, Chan Chung, Debra Hawes, Fusheng Yang, Alexander Judkins, Susanta Samajdar, Xuhong Cao, Lanbo Xiao, Abhijit Parolia, Arul Chinnaiyan, Sriram Venneti

Cancer Res (2024) 84 (5_Supplement_1): PR-007.

https://doi.org/10.1158/1538-7445.BRAIN23-PR-007

Published: 04 March 2024

View articletitled, Abstract PR-007: H3.3K27M diffuse midline gliomas are sensitive to SWI/SNF chromatin remodeler degradation

Journal Articles

Abstract A056: AR/FOXA1-mediated active gene repression as a mechanism of prostate carcinogenesis

Sanjana Eyunni, Abhijit Parolia, Eleanor Young, James George, Mustapha Jaber, Lanbo Xiao, Fengyun Su, Rui Wang, Xuhong Cao, Arul Chinnaiyan

Cancer Res (2023) 83 (11_Supplement): A056.

https://doi.org/10.1158/1538-7445.PRCA2023-A056

Published: 02 June 2023

View articletitled, Abstract A056: AR/FOXA1-mediated active gene repression as a mechanism of prostate carcinogenesis

Journal Articles

Abstract A055: NSD2 is a requisite and targetable subunit of the AR/FOXA1 neo-enhanceosome complex in prostate cancer cells

Cancer Res (2023) 83 (11_Supplement): A055.

https://doi.org/10.1158/1538-7445.PRCA2023-A055

Published: 02 June 2023

View articletitled, Abstract A055: NSD2 is a requisite and targetable subunit of the AR/FOXA1 neo-enhanceosome complex in prostate cancer cells

Journal Articles

Abstract 1685: Overcoming acquired resistance to PROTAC degraders

Tongchen He, Caleb Cheng, Abhijit Parolia, Alex Hopkins, Yuanyuan Qiao, Lanbo Xiao, Arul Chinnaiyan

Cancer Res (2023) 83 (7_Supplement): 1685.

https://doi.org/10.1158/1538-7445.AM2023-1685

Published: 04 April 2023

View articletitled, Abstract 1685: Overcoming acquired resistance to PROTAC degraders

Journal Articles

Abstract 3592: Targeting SWI/SNF ATPases in enhancer-addicted human cancers

Cancer Res (2022) 82 (12_Supplement): 3592.

https://doi.org/10.1158/1538-7445.AM2022-3592

Published: 15 June 2022

View articletitled, Abstract 3592: Targeting SWI/SNF ATPases in enhancer-addicted human cancers

Journal Articles

Abstract 5469: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer

Cancer Res (2022) 82 (12_Supplement): 5469.

https://doi.org/10.1158/1538-7445.AM2022-5469

Published: 15 June 2022

View articletitled, Abstract 5469: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer

Journal Articles

Abstract 3383: Circular RNAs as non-invasive diagnostic biomarkers for prostate cancer

Palak Shah, Pushpinder Bawa, Lanbo Xiao, Yelena Kleyman, Josh Vo, Saravana M. Dhanasekaran, Jason Brown, Nicolette Loeding, Alexander Koons, Javed Siddiqui, Xuhong Cao, Arul M. Chinnaiyan

Cancer Res (2022) 82 (12_Supplement): 3383.

https://doi.org/10.1158/1538-7445.AM2022-3383

Published: 15 June 2022

View articletitled, Abstract 3383: Circular RNAs as non-invasive diagnostic biomarkers for prostate cancer

Journal Articles

Abstract 5679: Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment

Steven Kregel, Chao Wang, Xin Han, Lanbo Xiao, Ester Fernandez-Salas, Pushpinder Bawa, Brooke L. McCollum, Kari Wilder-Romans, Ingrid J. Apel, Xuhong Cao, Corey Speers, Shaomeng Wang, Arul M. Chinnaiyan

Cancer Res (2020) 80 (16_Supplement): 5679.

https://doi.org/10.1158/1538-7445.AM2020-5679

Published: 15 August 2020

View articletitled, Abstract 5679: Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment

Journal Articles

Abstract 1278: Elucidating the mechanistic role of ERG in prostate cancer

Caleb Cheng, Lanbo Xiao, Jean Tien, Cynthia Wang, Jesse Cheng, Eileen Shiau, Xiaoju Wang, Arul M. Chinnaiyan

Cancer Res (2020) 80 (16_Supplement): 1278.

https://doi.org/10.1158/1538-7445.AM2020-1278

Published: 15 August 2020

View articletitled, Abstract 1278: Elucidating the mechanistic role of ERG in prostate cancer

Journal Articles

Abstract 3437: Cistromically-dominant class2 mutants of FOXA1 de-repress WNT signaling to drive prostate cancer metastasis

Abhijit Parolia, Marcin Cieslik, Sandra Carson, Shih-Chun Chu, Lanbo Xiao, Takahiro Ouchi, Mustapha Jaber, Yuping Zhang, Pankaj Vats, Xuhong Cao, Arul Chinnaiyan

Cancer Res (2020) 80 (16_Supplement): 3437.

https://doi.org/10.1158/1538-7445.AM2020-3437

Published: 15 August 2020

View articletitled, Abstract 3437: Cistromically-dominant class2 mutants of FOXA1 de-repress WNT signaling to drive prostate cancer metastasis

Journal Articles

Abstract 3573: Identification and functional characterization of prognostic long non coding RNA LADDER in lung cancer

Sathiya Pandi Narayanan, Sudhanshu Shukla, Jean Tien, Palak Shah, Sunita Shankar, Sethuramasundaram Pitchaiya, Srihari Srinivasan, Yuping Zhang, Xiaoming Wang, Lanbo Xiao, Xuhong Cao, Susan Freier, Andrew Watt, Shuling Guo, Felix Feng, David Beer, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Cancer Res (2019) 79 (13_Supplement): 3573.

https://doi.org/10.1158/1538-7445.AM2019-3573

Published: 01 July 2019

View articletitled, Abstract 3573: Identification and functional characterization of prognostic long non coding RNA LADDER in lung cancer

Journal Articles

Abstract 4153: Therapeutic targeting autophagy to sensitize cancer immunotherapy in various cancer types

Cancer Res (2019) 79 (13_Supplement): 4153.

https://doi.org/10.1158/1538-7445.AM2019-4153

Published: 01 July 2019

View articletitled, Abstract 4153: Therapeutic targeting autophagy to sensitize cancer immunotherapy in various cancer types

Journal Articles

Abstract 4503: Functional CRISPR screen towards identifying novel conserved long noncoding RNAs with oncogenic activity

Yajia Zhang, Lanbo Xiao, Mengyao Tan, Yasuyuki Hosono, Arul Chinnaiyan

Cancer Res (2019) 79 (13_Supplement): 4503.

https://doi.org/10.1158/1538-7445.AM2019-4503

Published: 01 July 2019

View articletitled, Abstract 4503: Functional CRISPR screen towards identifying novel conserved long noncoding RNAs with oncogenic activity

Journal Articles

Abstract 4497: Distinct structural classes of activating FOXA1 alterations in prostate cancer progression

Abhijit Parolia, Marcin Cieslik, Shih-Chun Chu, Lanbo Xiao, Takahiro Ouchi, Yuping Zhang, Xiaoju Wang, Pankaj Vats, Xuhong Cao, Fengyun Su, Rui Wang, Felix Feng, Yi-Mi Wu, Robert Lonigro, Dan R. Robinson, Arul M. Chinnaiyan

Cancer Res (2019) 79 (13_Supplement): 4497.

https://doi.org/10.1158/1538-7445.AM2019-4497

Published: 01 July 2019

View articletitled, Abstract 4497: Distinct structural classes of activating FOXA1 alterations in prostate cancer progression

Journal Articles

Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer

Cancer Res (2018) 78 (20): 5731–5740.

https://doi.org/10.1158/0008-5472.CAN-18-0941

Published: 15 October 2018

View articletitled, Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer

Includes: Supplementary data

Journal Articles

Abstract 1945: Degradation of ERG transcription factor as a targeted therapy in B-cell and T-cell acute lymphoblastic leukemia

Xiaoju Wang, Caleb Cheng, Yuanyuan Qiao, Lanbo Xiao, Cynthia Wang, Abhijit Parolia, Arul Chinnaiyan

Cancer Res (2018) 78 (13_Supplement): 1945.

https://doi.org/10.1158/1538-7445.AM2018-1945

Published: 01 July 2018

View articletitled, Abstract 1945: Degradation of ERG transcription factor as a targeted therapy in B-cell and T-cell acute lymphoblastic leukemia

Journal Articles

Abstract 975: Functional CRISPR screen towards identifying novel epigenetic co-factors of oncogenic AR-activity

Abhijit Parolia, Lanbo Xiao, Josh N. Vo, Marcin Cieslik, Xuhong Cao, Arul M. Chinnaiyan

Cancer Res (2018) 78 (13_Supplement): 975.

https://doi.org/10.1158/1538-7445.AM2018-975

Published: 01 July 2018

View articletitled, Abstract 975: Functional CRISPR screen towards identifying novel epigenetic co-factors of oncogenic AR-activity

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Abstract LB074: Targeting chromatin remodeling disrupts immune suppression by pathologically activated neutrophils in cancer

Abstract 3936: CDK12 tumor suppressor function and therapeutic targeting in newly developed mouse models of serous ovarian cancer

Abstract 6602: Targeting the SWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

Abstract PR-007: H3.3K27M diffuse midline gliomas are sensitive to SWI/SNF chromatin remodeler degradation

Abstract A056: AR/FOXA1-mediated active gene repression as a mechanism of prostate carcinogenesis

Abstract A055: NSD2 is a requisite and targetable subunit of the AR/FOXA1 neo-enhanceosome complex in prostate cancer cells

Abstract 1685: Overcoming acquired resistance to PROTAC degraders

Abstract 3592: Targeting SWI/SNF ATPases in enhancer-addicted human cancers

Abstract 5469: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer

Abstract 3383: Circular RNAs as non-invasive diagnostic biomarkers for prostate cancer

Abstract 5679: Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment

Abstract 1278: Elucidating the mechanistic role of ERG in prostate cancer

Abstract 3437: Cistromically-dominant class2 mutants of FOXA1 de-repress WNT signaling to drive prostate cancer metastasis

Abstract 3573: Identification and functional characterization of prognostic long non coding RNA LADDER in lung cancer

Abstract 4153: Therapeutic targeting autophagy to sensitize cancer immunotherapy in various cancer types

Abstract 4503: Functional CRISPR screen towards identifying novel conserved long noncoding RNAs with oncogenic activity

Abstract 4497: Distinct structural classes of activating FOXA1 alterations in prostate cancer progression

Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer

Abstract 1945: Degradation of ERG transcription factor as a targeted therapy in B-cell and T-cell acute lymphoblastic leukemia

Abstract 975: Functional CRISPR screen towards identifying novel epigenetic co-factors of oncogenic AR-activity

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