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L. Elizabeth Jackson
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Journal Articles

Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers

Mounia Beloueche-Babari, Vaitha Arunan, Helen Troy, Robert H. te Poele, Anne-Christine Wong Te Fong, L. Elizabeth Jackson, Geoffrey S. Payne, John R. Griffiths, Ian R. Judson, Paul Workman, Martin O. Leach, Yuen-Li Chung
Journal: Cancer Research
Cancer Res (2012) 72 (4): 990–1000.
https://doi.org/10.1158/0008-5472.CAN-11-2688
Published: 14 February 2012
View article titled, Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers
Open the PDF for Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 3788: Autophagy induced by DCA, PI3K inhibition or starvation results in reduced lactate production measured in real-time by DNP 13C MRS

Yuen-Li Chung, Gigin Lin, Helen Troy, Anne-Christine Wong Te Fong, L Elizabeth Jackson, Deborah K. Hill, Matthew Orton, Dow-Mu Koh, Simon P. Robinson, Ian R. Judson, John R. Griffiths, Martin O. Leach, Thomas R. Eykyn
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3788.
https://doi.org/10.1158/1538-7445.AM2011-3788
Published: 15 April 2011
View article titled, Abstract 3788: Autophagy induced by DCA, PI3K inhibition or starvation results in reduced lactate production measured in real-time by DNP 13C MRS
Journal Articles

Abstract 5277: Non-invasive metabolic biomarkers of histone deacetylase inhibition in human colon cancer cells and tumors

Mounia Beloueche-Babari, Vaitha Arunan, Helen Troy, L Elizabeth Jackson, Anne-Christine Wong, Paul Workman, Ian Judson, John R. Griffiths, Martin O. Leach, Yuen-Li Chung
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5277.
https://doi.org/10.1158/1538-7445.AM2011-5277
Published: 15 April 2011
View article titled, Abstract 5277: Non-invasive metabolic biomarkers of histone deacetylase inhibition in human colon cancer cells and tumors
Journal Articles

The Phosphoinositide 3-Kinase Inhibitor PI-103 Downregulates Choline Kinase α Leading to Phosphocholine and Total Choline Decrease Detected by Magnetic Resonance Spectroscopy

Nada M.S. Al-Saffar, L. Elizabeth Jackson, Florence I. Raynaud, Paul A. Clarke, Ana Ramírez de Molina, Juan C. Lacal, Paul Workman, Martin O. Leach
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5507–5517.
https://doi.org/10.1158/0008-5472.CAN-09-4476
Published: 30 June 2010
View article titled, The Phosphoinositide 3-Kinase Inhibitor PI-103 Downregulates Choline Kinase α Leading to Phosphocholine and Total Choline Decrease Detected by Magnetic Resonance Spectroscopy
Open the PDF for The Phosphoinositide 3-Kinase Inhibitor PI-103 Downregulates Choline Kinase α Leading to Phosphocholine and Total Choline Decrease Detected by Magnetic Resonance Spectroscopy in another window
Includes: Supplementary data
Journal Articles

Inhibition of cancer cell motility via PLC-γ1 downregulation is associated with altered choline metabolism: Implications for pharmacodynamic biomarker development

Mounia Beloueche-Babari, Joanna Peak, May-Yung Tiet, L Elizabeth Jackson, Suzanne Eccles, Martin Leach
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1358.
Published: 01 May 2007
View article titled, Inhibition of cancer cell motility via PLC-γ1 downregulation is associated with altered choline metabolism: Implications for pharmacodynamic biomarker development
Journal Articles

Magnetic Resonance Spectroscopy Monitoring of Mitogen-Activated Protein Kinase Signaling Inhibition

Mounia Beloueche-Babari, L. Elizabeth Jackson, Nada M.S. Al-Saffar, Paul Workman, Martin O. Leach, Sabrina M. Ronen
Journal: Cancer Research
Cancer Res (2005) 65 (8): 3356–3363.
https://doi.org/10.1158/10.1158/0008-5472.CAN-03-2981
Published: 15 April 2005
View article titled, Magnetic Resonance Spectroscopy Monitoring of Mitogen-Activated Protein Kinase Signaling Inhibition
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