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Kwon-Sik Park
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Journal Articles

Abstract 1714: CRACD/KIAA1211 loss drives cell plasticity and immune evasion of small cell lung cancer

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Shengzhe Zhang, Kee-Bum Kim, Yuanjian Huang, Dong-Wook Kim, Bongjun Kim, Kyung-Pil Ko, Gengyi Zou, Jie Zhang, Sohee Jun, Nicole A. Kirk, Ye Eun Hwang, Young Ho Ban, Joseph M. Chan, Charles M. Rudin, Kwon-Sik Park, Jae-Il Park
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1714.
https://doi.org/10.1158/1538-7445.AM2023-1714
Published: 04 April 2023
View articletitled, Abstract 1714: CRACD/KIAA1211 loss drives cell plasticity and immune evasion of small cell lung cancer
Journal Articles

WNT5A–RHOA Signaling Is a Driver of Tumorigenesis and Represents a Therapeutically Actionable Vulnerability in Small Cell Lung Cancer

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Kee-Beom Kim, Dong-Wook Kim, Youngchul Kim, Jun Tang, Nicole Kirk, Yongyu Gan, Bongjun Kim, Bingliang Fang, Jae-ll Park, Yi Zheng, Kwon-Sik Park
Journal: Cancer Research
Cancer Res (2022) 82 (22): 4219–4233.
https://doi.org/10.1158/0008-5472.CAN-22-1170
Published: 15 November 2022
View articletitled, WNT5A–RHOA Signaling Is a Driver of Tumorigenesis and Represents a Therapeutically Actionable Vulnerability in Small Cell Lung Cancer
Open the PDF for WNT5A–RHOA Signaling Is a Driver of Tumorigenesis and Represents a Therapeutically Actionable Vulnerability in Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

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Dylan L. Schaff, Shambhavi Singh, Kee-Beom Kim, Matthew D. Sutcliffe, Kwon-Sik Park, Kevin A. Janes
Journal: Cancer Research
Cancer Res (2021) 81 (7): 1853–1867.
https://doi.org/10.1158/0008-5472.CAN-20-1036
Published: 01 April 2021
View articletitled, Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments
Open the PDF for Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments in another window
Includes: Supplementary data
Journal Articles

FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

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Kee-Beom Kim, Youngchul Kim, Christopher J. Rivard, Dong-Wook Kim, Kwon-Sik Park
Journal: Cancer Research
Cancer Res (2020) 80 (22): 5051–5062.
https://doi.org/10.1158/0008-5472.CAN-20-1453
Published: 13 November 2020
View articletitled, FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer
Open the PDF for FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract A38: A critical role of Wnt5a-Axin2 axis in small-cell lung cancer development

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Kee-Beom Kim, Dong-Wook Kim, Youngchul Kim, Jae-Il Park, Kwon-Sik Park
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): A38.
https://doi.org/10.1158/1538-7445.CAMODELS2020-A38
Published: 02 June 2020
View articletitled, Abstract A38: A critical role of Wnt5a-Axin2 axis in small-cell lung cancer development
Journal Articles

Abstract PHA04: A new somatic engineering-based model of small-cell lung cancer development

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Kee-Beom Kim, Dong-Wook Kim, Kwon-Sik Park
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): PHA04.
https://doi.org/10.1158/1538-7445.CAMODELS2020-PHA04
Published: 02 June 2020
View articletitled, Abstract PHA04: A new somatic engineering-based model of small-cell lung cancer development
Journal Articles

Abstract 3200: Immunotuning CD8+ T cells with BCAT1 inhibition to increase the efficacy of anti-PD-1 therapy and to eradicate moderately immunogenic tumors

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Adonia E. Papathanassiu, Dong-Wook Kim, Kwon-Sik Park, Jeong Hun Ko, Jacques V. Behmoaras
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3200.
https://doi.org/10.1158/1538-7445.AM2019-3200
Published: 01 July 2019
View articletitled, Abstract 3200: Immunotuning CD8+ T cells with BCAT1 inhibition to increase the efficacy of anti-PD-1 therapy and to eradicate moderately immunogenic tumors
Journal Articles

Loss of p130 Accelerates Tumor Development in a Mouse Model for Human Small-Cell Lung Carcinoma

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Bethany E. Schaffer, Kwon-Sik Park, Gloria Yiu, Jamie F. Conklin, Chenwei Lin, Deborah L. Burkhart, Anthony N. Karnezis, E. Alejandro Sweet-Cordero, Julien Sage
Journal: Cancer Research
Cancer Res (2010) 70 (10): 3877–3883.
https://doi.org/10.1158/0008-5472.CAN-09-4228
Published: 12 May 2010
View articletitled, Loss of p130 Accelerates Tumor Development in a Mouse Model for Human Small-Cell Lung Carcinoma
Open the PDF for Loss of p130 Accelerates Tumor Development in a Mouse Model for Human Small-Cell Lung Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 5755: Molecular mechanisms of small cell lung carcinoma development using preclinical mouse models

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Kwon-Sik Park, Julien Sage
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5755.
https://doi.org/10.1158/1538-7445.AM10-5755
Published: 15 April 2010
View articletitled, Abstract 5755: Molecular mechanisms of small cell lung carcinoma development using preclinical mouse models