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Journal Articles

FOXP4 Is a Direct YAP1 Target That Promotes Gastric Cancer Stemness and Drives Metastasis

Xiaoli Liu, Bonan Chen, Fuda Xie, Kit Yee Wong, Alvin H.K. Cheung, Jinglin Zhang, Qian Wu, Canbin Fang, Jintao Hu, Shouyu Wang, Dazhi Xu, Jianwu Chen, Yuzhi Wang, Chi Chun Wong, Huarong Chen, William K.K. Wu, Jun Yu, Michael W.Y. Chan, Chi Man Tsang, Kwok Wai Lo, Gary M.K. Tse, Ka-Fai To, Wei Kang
Journal: Cancer Research
Cancer Res (2024) 84 (21): 3574–3588.
https://doi.org/10.1158/0008-5472.CAN-23-3074
Published: 04 November 2024
View article titled, FOXP4 Is a Direct YAP1 Target That Promotes Gastric Cancer Stemness and Drives Metastasis
Open the PDF for FOXP4 Is a Direct YAP1 Target That Promotes Gastric Cancer Stemness and Drives Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 6226: Therapeutic vulnerability of MTAP-deleted nasopharyngeal carcinoma by MAT2A inhibitors

YUK-Yu Chan, Chi-Man Tsang, Grace T.Y. Chung, Ka-Fai To, Yi Zhang, Xiaodong Zhang, Jun Tang, Kwok Wai Lo
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6226.
https://doi.org/10.1158/1538-7445.AM2023-6226
Published: 04 April 2023
View article titled, Abstract 6226: Therapeutic vulnerability of <em>MTAP</em>-deleted nasopharyngeal carcinoma by MAT2A inhibitors
Journal Articles

Abstract 5514: Therapeutic potential of activated natural killer cells in nasopharyngeal carcinoma

Shinyee Hui, Kwok Wai Lo, Mingjing Xu, Siu Tim Cheung
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5514.
https://doi.org/10.1158/1538-7445.AM2022-5514
Published: 15 June 2022
View article titled, Abstract 5514: Therapeutic potential of activated natural killer cells in nasopharyngeal carcinoma
Journal Articles

Abstract 948: Preclinical evaluation of VEGF Ang2 bispecific nanobody BI836880 in patient-derived xenograft models of nasopharyngeal carcinoma

Eric Chi Wong, Gigi Lam, Connie Wong, Rachel C. Lam, Kwok Wai Lo, Edwin Pun Hui, Anthony Tak Chan, Brigette B. Ma
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 948.
https://doi.org/10.1158/1538-7445.AM2021-948
Published: 01 July 2021
View article titled, Abstract 948: Preclinical evaluation of VEGF Ang2 bispecific nanobody BI836880 in patient-derived xenograft models of nasopharyngeal carcinoma
Journal Articles

Abstract 3062: Proton irradiation sensitizes cancer cell lines with acquired radioresistance by exploiting differentially dysregulated DNA damage response (DDR) pathways

Pek Lim Chu, Eugenia L.L. Yeo, Dennis J.J. Poon, Ce-belle Chen, Minqin Ren, Saumitra Vajandar, Dewi Susanti, Hong Qi Tan, Sung Yong Park, Thomas Osipowicz, Kwok Wai Lo, Stanley K. Liu, Khee Chee Soo, Melvin Lk Chua
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3062.
https://doi.org/10.1158/1538-7445.AM2021-3062
Published: 01 July 2021
View article titled, Abstract 3062: Proton irradiation sensitizes cancer cell lines with acquired radioresistance by exploiting differentially dysregulated DNA damage response (DDR) pathways
Journal Articles

Abstract LB098: Vulnerability of MTAP-deleted nasopharyngeal carcinoma to MAT2A inhibition

Yuk Yu Chan, Jeff P. Bruce, Vivian W.Y. Lui, Grace T. Y. Chung, Sai-Wah Tsao, Ka-Fai To, Trevor J. Pugh, Kwok-Wai Lo
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB098.
https://doi.org/10.1158/1538-7445.AM2021-LB098
Published: 01 July 2021
View article titled, Abstract LB098: Vulnerability of <em>MTAP</em>-deleted nasopharyngeal carcinoma to MAT2A inhibition
Journal Articles

Abstract 1792: MAPK1 p.D321N mutation confers sensitive to erlotinib in head and neck squamous cell carcinoma (HNSCC)

Hoi Lam Ngan, Peony Hiu Yan Poon, Yu-Xiong Su, Jason Yik Kuen Chan, Kwok-Wai Lo, Chun Kit Yeung, Yuchen Liu, Eileen Wong, Hui Li, Chin Wang Lau, Wenying Piao, Vivian Wai Yan Lui
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1792.
https://doi.org/10.1158/1538-7445.AM2020-1792
Published: 15 August 2020
View article titled, Abstract 1792: <em>MAPK1</em> p.D321N mutation confers sensitive to erlotinib in head and neck squamous cell carcinoma (HNSCC)
Journal Articles

Abstract 2923: Targeting the polycomb repressive complex-2 related proteins in nasopharyngeal carcinoma

Junyu ZHU, Lili Li, Connie W. Hui, Joanna H. Tong, Raymond Chan, Chi Hang Wong, Qiyong Ai, Edwin P. Hui, Anthony T. Chan, Kwok Wai Lo, Qian Tao, Brigette B. Ma
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2923.
https://doi.org/10.1158/1538-7445.AM2020-2923
Published: 15 August 2020
View article titled, Abstract 2923: Targeting the polycomb repressive complex-2 related proteins in nasopharyngeal carcinoma
Journal Articles

Abstract 4180: Therapeutic targeting of STAT3 in nasopharyngeal carcinoma

Shinyee Hui, Kwok Wai Lo, Alyssa Ming-Ting Liu, Marcus Hung-Nam Law, Linda Wing-Chi Ng, Peter Tin-Chung Li, Siu Tim Cheung
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4180.
https://doi.org/10.1158/1538-7445.AM2020-4180
Published: 15 August 2020
View article titled, Abstract 4180: Therapeutic targeting of STAT3 in nasopharyngeal carcinoma
Journal Articles

Abstract 56: Establishment and characterization of new tumor xenografts and cancer cell lines from EBV positive nasopharyngeal carcinoma

Weitao Lin, Yim Ling Yip, Lin Jia, Wen Deng, Kwok Wai Lo, Chin Man Tsang, Maria Li Lung, George Sai Tsao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 56.
https://doi.org/10.1158/1538-7445.AM2019-56
Published: 01 July 2019
View article titled, Abstract 56: Establishment and characterization of new tumor xenografts and cancer cell lines from EBV positive nasopharyngeal carcinoma
Journal Articles

Abstract 2462: Epstein-Barr virus-encoded microRNAs regulate the expression of BRCA1 in nasopharyngeal carcinoma

Ka-Hei Lam, Raymond Wai-Ming Lung, Pok-Man Hau, Kevin Yuk-Lap Yip, George Sai-Wah Tsao, Ken Hung-On Yu, Joanna Hung-Man Tong, Kwok-Wai Lo, Ka-Fai To
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2462.
https://doi.org/10.1158/1538-7445.AM2018-2462
Published: 01 July 2018
View article titled, Abstract 2462: Epstein-Barr virus-encoded microRNAs regulate the expression of BRCA1 in nasopharyngeal carcinoma
Journal Articles

Abstract 482: Epstein-Barr virus-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma

Raymond W. Lung, Po-Man Hau, Joanna H. Tong, Ka-Hei Lam, Anthony W. Chan, Kevin Y. Yip, George S. Tsao, Kwok-Wai Lo, Ka-Fai To
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 482.
https://doi.org/10.1158/1538-7445.AM2018-482
Published: 01 July 2018
View article titled, Abstract 482: Epstein-Barr virus-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma
Journal Articles

Abstract 4563: PD-L1 expression associated with treatment responses in colorectal cancer patients with XELOX/FOLFOX chemotherapy: Potential of checkpoint blockage and natural killer cell-based immunotherapy

Elaine H.L. SIU, Simon S.M. NG, Anthony W.H. CHAN, James Y.W. LAU, Kwok Wai LO, Charing C.N. CHONG, Paul B.S. LAI, Stephen L. CHAN, Marcus H.N. LAW, Linda W.C. NG, S.T. CHEUNG
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4563.
https://doi.org/10.1158/1538-7445.AM2018-4563
Published: 01 July 2018
View article titled, Abstract 4563: PD-L1 expression associated with treatment responses in colorectal cancer patients with XELOX/FOLFOX chemotherapy: Potential of checkpoint blockage and natural killer cell-based immunotherapy
Journal Articles

Abstract 5347: Somatic mutation and overexpression of anaplastic lymphoma kinase (ALK) are uncommon events in Asian head and neck cancers

Wenying Piao, Peony Hiu Yan Poon, Lan Wang, Chin Wang Lau, Jason Ying Kuen Chan, Yuxiong Su, Amy Bik Wan Chan, Hoi Lam Ngan, Kwok Wai Lo, Vivian Wai Yan Lui
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5347.
https://doi.org/10.1158/1538-7445.AM2018-5347
Published: 01 July 2018
View article titled, Abstract 5347: Somatic mutation and overexpression of anaplastic lymphoma kinase (ALK) are uncommon events in Asian head and neck cancers
Journal Articles

Abstract 646: Targeting MHC class I molecules and immune checkpoints as key immune evasion strategies in EBV-associated nasopharyngeal carcinoma

Sharie Pui-Kei Siu, Ka Fai To, Grace Tin-Yun Chung, Vivian W.Y. Lui, Yvonne Y. Li, Peter S. Hammerman, Kwok Wai Lo
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 646.
https://doi.org/10.1158/1538-7445.AM2017-646
Published: 01 July 2017
View article titled, Abstract 646: Targeting MHC class I molecules and immune checkpoints as key immune evasion strategies in EBV-associated nasopharyngeal carcinoma
Journal Articles

Abstract 4382: Genomic events associated with metastasis of colorectal cancer by whole-genome sequencing

Yi Pan, Joanna Tong, Johnny Kwan, Kwok Wai Lo, Anthony Chan, Ka Fai To
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4382.
https://doi.org/10.1158/1538-7445.AM2017-4382
Published: 01 July 2017
View article titled, Abstract 4382: Genomic events associated with metastasis of colorectal cancer by whole-genome sequencing
Journal Articles

Abstract 4064: The identification of UBR5-ZNF423 recurrent fusion gene in EBV-associated nasopharyngeal carcinoma

Pok Man Hau, Grace Chung, Raymond Lung, Samantha Lun, Chit Chow, Alice Wong, Fei-Fei Liu, George Tsao, Kevin Yip, Ka Fai To, Kwok Wai Lo
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4064.
https://doi.org/10.1158/1538-7445.AM2016-4064
Published: 15 July 2016
View article titled, Abstract 4064: The identification of UBR5-ZNF423 recurrent fusion gene in EBV-associated nasopharyngeal carcinoma
Journal Articles

Abstract 1118: The role of Epstein-Barr virus-encoded miRNAs in ATM regulating DNA damage response in nasopharyngeal carcinoma

RAYMOND Wai-Ming LUNG, Tom Pok-Man Hau, Wing-Po Chak, Joanna Hung-Man Tong, Ken Hung-On Yu, Sai-Wah Tsao, Kevin Yuk-Lap Yip, Ka-Fai To, Kwok-Wai Lo
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1118.
https://doi.org/10.1158/1538-7445.AM2016-1118
Published: 15 July 2016
View article titled, Abstract 1118: The role of Epstein-Barr virus-encoded miRNAs in ATM regulating DNA damage response in nasopharyngeal carcinoma
Journal Articles

Abstract 1529: RASAL2 promotes tumor progression and metastasis in colorectal cancer

Yi PAN, Joanna Hung Man TONG, Raymond Wai Ming LUNG, Samantha Wei Man LUN, Kwok Wai LO, Anthony Wing Hung CHAN, Ka Fai TO.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1529.
https://doi.org/10.1158/1538-7445.AM2016-1529
Published: 15 July 2016
View article titled, Abstract 1529: RASAL2 promotes tumor progression and metastasis in colorectal cancer
Journal Articles

Abstract 1734: Preclinical study of HSP-90 inhibitor drug, AUY922 showed good efficacy in treatment of nasopharyngeal cancer

Timothy T.C. Yip, Roger K.C. Ngan, Wai-Tong Ng, Lewis T.C. Chan, William C.S. Tai, Wai-Wai Cheng, Victor W.S. Ma, Kwok-Wai Lo, Ya-Ping Li, Michael B.H. Yang, Eric C.H. Wong, Brigette B.Y. Ma, Nai-Ki Mak, George S.W. Tsao, Maria Li-Lung
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1734.
https://doi.org/10.1158/1538-7445.AM2015-1734
Published: 01 August 2015
View article titled, Abstract 1734: Preclinical study of HSP-90 inhibitor drug, AUY922 showed good efficacy in treatment of nasopharyngeal cancer