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Kwang Hwa Jung
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Journal Articles

Abstract 1898: LNCB74 is a potent and safe next-generation antibody-drug-conjugate utilizing a cancer selective linker for the treatment of B7-H4 expressing cancers

Daniel P. Fitzgerald, Duc N. Doan, Riley B. Peacock, Shannon M. Kahan, Suvendu Lomash, Stephen Slocum, Kwang Hwa Jung, Hwanhee Oh, Ingrid Meza, Yanira Manzanarez, Shanmugam Selvam, Dallas B. Flies, Chul-Woong Chung, Sol Langermann
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1898.
https://doi.org/10.1158/1538-7445.AM2024-1898
Published: 22 March 2024
View articletitled, Abstract 1898: LNCB74 is a potent and safe next-generation antibody-drug-conjugate utilizing a cancer selective linker for the treatment of B7-H4 expressing cancers
Journal Articles

Abstract 294: Tumor concentration of metformin is a determinant factor of its regulation of fatty acid β-oxidation and c-Src pathway in triple-negative breast cancer

Junhyoung Park, Kwang Hwa Jung, Dongya Jia, Sukjin Yang, Kuldeep S. Attri, Songyeon Ahn, Divya Murthy, Meron Ghidey, Somik Chatterjee, Diego A. Pedroza, Abha Tiwari, Suna Kim, Chad C. Creighton, Nagireddy Putluri, Jeffrey M. Rosen, José N. Onuchic, Andrei Goga, Benny A. Kaipparettu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 294.
https://doi.org/10.1158/1538-7445.AM2023-294
Published: 04 April 2023
View articletitled, Abstract 294: Tumor concentration of metformin is a determinant factor of its regulation of fatty acid β-oxidation and c-Src pathway in triple-negative breast cancer
Journal Articles

Abstract P5-05-06: Metformin concentration is a deciding factor of its pro- or anti-tumor function in triple negative breast cancer

Jun Hyoung Park, Dongya Jia, Sukjin Yang, Kwang Hwa Jung, Abha Tiwari, Debasmita Dutta, Meron Ghidey, Nagireddy Putluri, Cristian Coarfa, Chad Creighton, José N. Onuchic, Benny A Kaipparettu
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-05-06.
https://doi.org/10.1158/1538-7445.SABCS21-P5-05-06
Published: 15 February 2022
View articletitled, Abstract P5-05-06: Metformin concentration is a deciding factor of its pro- or anti-tumor function in triple negative breast cancer
Journal Articles

Abstract 2397: Significance of the combination of biguanides and fatty acid β-oxidation inhibitors in triple-negative breast cancer

Junhyoung Park, Kwang Hwa Jung, Dongya Jia, Sukjin Yang, Dharaniya Sakthivel, Abha Tiwari, José N. Onuchic, Benny Abraham Kaipparettu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2397.
https://doi.org/10.1158/1538-7445.AM2021-2397
Published: 01 July 2021
View articletitled, Abstract 2397: Significance of the combination of biguanides and fatty acid β-oxidation inhibitors in triple-negative breast cancer
Journal Articles

Abstract P3-06-16: Synergistic effect of biguanides and fatty acid β-oxidation inhibitor in triple-negative breast cancers

Jun Hyoung Park, Kwang Hwa Jung, Dongya Jia, Benny A Kaipparettu
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-06-16.
https://doi.org/10.1158/1538-7445.SABCS19-P3-06-16
Published: 15 February 2020
View articletitled, Abstract P3-06-16: Synergistic effect of biguanides and fatty acid β-oxidation inhibitor in triple-negative breast cancers
Journal Articles

Abstract 2448: Elucidating the metabolic plasticity of cancer by coupling gene regulation with metabolic pathways

Dongya Jia, Mingyang Lu, Kwang Hwa Jung, Jun Hyoung Park, José N. Onuchic, Benny Abraham Kaipparettu, Herbert Levine
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2448.
https://doi.org/10.1158/1538-7445.AM2019-2448
Published: 01 July 2019
View articletitled, Abstract 2448: Elucidating the metabolic plasticity of cancer by coupling gene regulation with metabolic pathways
Journal Articles

Abstract 1331: Inhibition of mitochondrial reprogramming regulated c-Src in triple-negative breast cancer activates autophagy-mediated survival mechanism

Kwang Hwa Jung, Jun Hyoung Park, Tirupataiah Sirupangi, Dongya Jia, Shivanand Pudakalakatti, Nishant Gandhi, Jessica Elswood, Vasanta Putluri, Chad J. Creighton, Weston Porter, Michael T. Lewis, Xi Chen, Nagireddy Putluri, Pratip K. Bhattacharya, Lee-Jun C. Wong, Gokul M. Das, Benny A. Kaipparettu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1331.
https://doi.org/10.1158/1538-7445.AM2018-1331
Published: 01 July 2018
View articletitled, Abstract 1331: Inhibition of mitochondrial reprogramming regulated c-Src in triple-negative breast cancer activates autophagy-mediated survival mechanism
Journal Articles

Abstract 1507: Fatty acid oxidation mediated autophagy regulation in triple negative breast cancer

Kwang Hwa Jung, Jun Hyoung Park, Tirupataiah Sirupangi, Sajna Vithayathil, Lee-Jun Wong, Benny A. Kaipparettu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1507.
https://doi.org/10.1158/1538-7445.AM2017-1507
Published: 01 July 2017
View articletitled, Abstract 1507: Fatty acid oxidation mediated autophagy regulation in triple negative breast cancer
Journal Articles

Abstract 1116: Targeting replication stress by carbazole blue- A novel strategy to treat triple negative breast cancers

Subapriya Rajamanickam, Kaitlyn Bates, Santosh Timilsina, JunHyoung Park, Benjamin Onyeagucha, Panneerdoss Subbarayalu, Nourhan Abdelfattah, Kwang Hwa Jung, Edward Favours, Tabrez A. Mohammad, Hung-I Harry Chen, Benny A. Kaipparettu, Yidong Chen, Jack L. Arbiser, Manjeet K Rao
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1116.
https://doi.org/10.1158/1538-7445.AM2017-1116
Published: 01 July 2017
View articletitled, Abstract 1116: Targeting replication stress by carbazole blue- A novel strategy to treat triple negative breast cancers
Journal Articles

miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells

Jing Zhang, Jingjing Jiao, Silvia Cermelli, Kyle Muir, Kwang Hwa Jung, Ruhai Zou, Asif Rashid, Mihai Gagea, Sonya Zabludoff, Raghu Kalluri, Laura Beretta
Journal: Cancer Research
Cancer Res (2015) 75 (9): 1859–1867.
https://doi.org/10.1158/0008-5472.CAN-14-1254
Published: 30 April 2015
View articletitled, miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells
Open the PDF for miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 5290: MicroRNA-495-3p functions as tumor suppressor by targeting multiple oncogenic epigenetic effector molecules in gastric cancer.

Min Gyu Kim, Seung Jin Kim, Hyun Jin Bae, Ji Heon Noh, Jeong Kyu Kim, Jung Woo Eun, Kwang Hwa Jung, Young Gyoon Chang, Qingyu Shen, Won Sang Park, Jung Young Lee, Suk Woo Nam
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5290.
https://doi.org/10.1158/1538-7445.AM2013-5290
Published: 15 April 2013
View articletitled, Abstract 5290: MicroRNA-495-3p functions as tumor suppressor by targeting multiple oncogenic epigenetic effector molecules in gastric cancer.
Journal Articles

Abstract 179: MicroRNA-29c functions as a tumor suppressor by direct targeting endogenous SIRT1 in hepatocarcinogenesis

Hyun Jin Bae, Ji Heon Noh, Jeong Kyu Kim, Jung Woo Eun, Kwang Hwa Jung, Min Kyu Kim, Young Gyoon Chang, Won Sang Park, Suk Woo Nam
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 179.
https://doi.org/10.1158/1538-7445.AM2012-179
Published: 15 April 2012
View articletitled, Abstract 179: MicroRNA-29c functions as a tumor suppressor by direct targeting endogenous SIRT1 in hepatocarcinogenesis
Journal Articles

Abstract 2865: Cytoplasmic deacetylase HDAC6 confers tumor suppressive potential through autophagic cell death in human hepatocellular carcinoma

Kwang Hwa Jung, Ji Heon Noh, Jung Woo Eun, Jeong Kyu Kim, Hyun Jin Bae, Hongjian Xie, Eliel Nam, Won Sang Park, Jung Young Lee, Suk Woo Nam
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2865.
https://doi.org/10.1158/1538-7445.AM2011-2865
Published: 15 April 2011
View articletitled, Abstract 2865: Cytoplasmic deacetylase HDAC6 confers tumor suppressive potential through autophagic cell death in human hepatocellular carcinoma
Journal Articles

Abstract 1079: Targeted disruption of Nemo-like kinase inhibits tumor cell growth by simultaneous suppression of cyclin D1 and CDK2 in human hepatocellular carcinoma

Kwang Hwa Jung, eong Kyu Kim, Ji Hein Noh, Jung Woo Eun, Hyun JIn Bae, Hong Jian Xie, Wong Sang Park, Jung Young Lee, Suk Woo Nam
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1079.
https://doi.org/10.1158/1538-7445.AM10-1079
Published: 15 April 2010
View articletitled, Abstract 1079: Targeted disruption of Nemo-like kinase inhibits tumor cell growth by simultaneous suppression of cyclin D1 and CDK2 in human hepatocellular carcinoma
Journal Articles

Abstract #1275: Targeted-disruption of histone deacetylase 2 suppresses cell growth through transcriptional induction of p21WAF1/CIP1 and inhibition of cyclin E2/CDK2 complex in human lung cancer cells

Kwang Hwa Jung, Ji Heon Noh, Jeong Kyu Kim, Jung Woo Eun, Hyun Jin Bae, Hongjian Xie, Wong Sang Park, Jung Young Lee, Suk Woo Nam
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1275.
Published: 01 May 2009
View articletitled, Abstract #1275: Targeted-disruption of histone deacetylase 2 suppresses cell growth through transcriptional induction of p21WAF1/CIP1 and inhibition of cyclin E2/CDK2 complex in human lung cancer cells
Journal Articles

Suppression of histone deacetylase 2 elicits cell-cycle arrest through the induction of p21WAF1/CIP1 followed by the inhibition of cyclin E2/CDK2 complex in A549 human lung cancer cells

Kwang Hwa Jung, Ji Heon Noh, Jung Woo Eun, Jeong Kyu Kim, Hyun Jin Bae, Hong Jian Xie, Won Sang Park, Jung Young Lee, Suk Woo Nam
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4236.
Published: 01 May 2008
View articletitled, Suppression of histone deacetylase 2 elicits cell-cycle arrest through the induction of p21WAF1/CIP1 followed by the inhibition of cyclin E2/CDK2 complex in A549 human lung cancer cells
Journal Articles

Identification of systemic cell-cycle suppression by Apicidin, a histone deacetylase inhibitor, through characteristic molecular signature in breast cancer cells

Ji Heoun Noh, Haehwi Song, Jung Woo Eun, Kwang Hwa Jung, Hong Jian Xie, Won Sang Park, Jung Young Lee, Suk Woo Nam
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4234.
Published: 01 May 2008
View articletitled, Identification of systemic cell-cycle suppression by Apicidin, a histone deacetylase inhibitor, through characteristic molecular signature in breast cancer cells
Journal Articles

Aberrant regulation of histone deacetlyase 2 suppresses systemic cell-cycle regulatory circuit in human hepatocellular cacrcinoma

Ji Heon Noh, Jung Woo Eun, So Yeon Ryu, Jung Kyu Kim, Kwang Hwa Jung, Sug Hyung Lee, Won Sang Park, Nam Jin Yoo, Jung Young Lee, Suk Woo Nam
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4563.
Published: 01 May 2007
View articletitled, Aberrant regulation of histone deacetlyase 2 suppresses systemic cell-cycle regulatory circuit in human hepatocellular cacrcinoma