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Journal Articles

Inactivation of the Prolyl Isomerase Pin1 Sensitizes BRCA1-Proficient Breast Cancer to PARP Inhibition

Available to Purchase
Man-Li Luo, Fang Zheng, Wenying Chen, Zhi-Mei Liang, Gurushankar Chandramouly, Jianan Tan, Nicholas A. Willis, Chun-Hau Chen, Mateus de Oliveira Taveira, Xiao Zhen Zhou, Kun Ping Lu, Ralph Scully, Gerburg M. Wulf, Hai Hu
Journal: Cancer Research
Cancer Res (2020) 80 (14): 3033–3045.
https://doi.org/10.1158/0008-5472.CAN-19-2739
Published: 15 July 2020
View articletitled, Inactivation of the Prolyl Isomerase Pin1 Sensitizes BRCA1-Proficient Breast Cancer to PARP Inhibition
Open the PDF for Inactivation of the Prolyl Isomerase Pin1 Sensitizes BRCA1-Proficient Breast Cancer to PARP Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract 2757: Discovery and characterization of covalent Pin1 inhibitors targeted to an active site cysteine

Free
Benika Pinch, Zainab Doctor, Christopher M. Browne, Hyuk-Soo Seo, Behnam Nabet, Shingo Kozono, Xiaolan Lian, Daniel Zaidman, Dina Daitchman, Nir London, Lu Gong, Theresa Manz, Yujin Chun, Li Tan, Jarrod Marto, Stephen Buratowski, Sirano Dhe-Paganon, Xiao Zhou, Kun Ping Lu, Nathanael S. Gray
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2757.
https://doi.org/10.1158/1538-7445.AM2019-2757
Published: 01 July 2019
View articletitled, Abstract 2757: Discovery and characterization of covalent Pin1 inhibitors targeted to an active site cysteine
Journal Articles

Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem–like Cell Traits in Breast Cancer

Free
Man-Li Luo, Chang Gong, Chun-Hau Chen, Daniel Y. Lee, Hai Hu, Pengyu Huang, Yandan Yao, Wenjun Guo, Ferenc Reinhardt, Gerburg Wulf, Judy Lieberman, Xiao Zhen Zhou, Erwei Song, Kun Ping Lu
Journal: Cancer Research
Cancer Res (2014) 74 (13): 3603–3616.
https://doi.org/10.1158/0008-5472.CAN-13-2785
Published: 30 June 2014
View articletitled, Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem–like Cell Traits in Breast Cancer
Open the PDF for Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem–like Cell Traits in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

SENP1 deSUMOylates and Regulates Pin1 Protein Activity and Cellular Function

Free
Chun-Hau Chen, Che-Chang Chang, Tae Ho Lee, ManLi Luo, Pengyu Huang, Pei-Hsin Liao, Shuo Wei, Fu-An Li, Ruey-Hwa Chen, Xiao Zhen Zhou, Hsiu-Ming Shih, Kun Ping Lu
Journal: Cancer Research
Cancer Res (2013) 73 (13): 3951–3962.
https://doi.org/10.1158/0008-5472.CAN-12-4360
Published: 30 June 2013
View articletitled, SENP1 deSUMOylates and Regulates Pin1 Protein Activity and Cellular Function
Open the PDF for SENP1 deSUMOylates and Regulates Pin1 Protein Activity and Cellular Function in another window
Includes: Supplementary data
Journal Articles

Abstract 919: Death associated protein kinase 1 phosphoylates Pin1 and inhibits its cellular function

Free
Tae Ho Lee, Chun-Hau Chen, Xiao Zhen Zhou, Kun Ping Lu
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 919.
https://doi.org/10.1158/1538-7445.AM2011-919
Published: 15 April 2011
View articletitled, Abstract 919: Death associated protein kinase 1 phosphoylates Pin1 and inhibits its cellular function
Journal Articles

Abstract 1009: Critical role of Pin1 for the regulation of TRF1 stability and ubiquitination

Free
Tae Ho Lee, Xiao Zhen Zhou, Kun Ping Lu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1009.
https://doi.org/10.1158/1538-7445.AM10-1009
Published: 15 April 2010
View articletitled, Abstract 1009: Critical role of Pin1 for the regulation of TRF1 stability and ubiquitination
Journal Articles

Peptidyl-Prolyl Isomerase Pin1 Markedly Enhances the Oncogenic Activity of the Rel Proteins in the Nuclear Factor-κB Family

Free
Gaofeng Fan, Yongjun Fan, Nupur Gupta, Isao Matsuura, Fang Liu, Xiao Zhen Zhou, Kun Ping Lu, Céline Gélinas
Journal: Cancer Research
Cancer Res (2009) 69 (11): 4589–4597.
https://doi.org/10.1158/0008-5472.CAN-08-4117
Published: 01 June 2009
View articletitled, Peptidyl-Prolyl Isomerase Pin1 Markedly Enhances the Oncogenic Activity of the Rel Proteins in the Nuclear Factor-κB Family
Open the PDF for Peptidyl-Prolyl Isomerase Pin1 Markedly Enhances the Oncogenic Activity of the Rel Proteins in the Nuclear Factor-κB Family in another window
Includes: Supplementary data
Journal Articles

Abstract #1959: The phosphorylation specific isomerase Pin1 regulates TRF1 protein stability, telomere maintenance, and aging

Free
Tae Ho Lee, Xiao Zhen Zhou, Kun Ping Lu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1959.
Published: 01 May 2009
View articletitled, Abstract #1959: The phosphorylation specific isomerase Pin1 regulates TRF1 protein stability, telomere maintenance, and aging
Journal Articles

Prolyl isomerase Pin1 as a potential treatment target in her2-positive breast cancer

Free
Prudence Lam, Bryan Wu, Erin Hofstatter, Mark Wotkowicz, Stephen Cannistra, Kun Ping Lu, Gerburg Wulf
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 842–843.
Published: 15 April 2006
View articletitled, Prolyl isomerase Pin1 as a potential treatment target in her2-positive breast cancer
Journal Articles

The Prolyl Isomerase Pin1 Is a Novel Prognostic Marker in Human Prostate Cancer

Free
Gustavo Ayala, Dagong Wang, Gerburg Wulf, Anna Frolov, Rile Li, Janusz Sowadski, Thomas M. Wheeler, Kun Ping Lu, Lere Bao
Journal: Cancer Research
Cancer Res (2003) 63 (19): 6244–6251.
Published: 14 October 2003
View articletitled, The Prolyl Isomerase Pin1 Is a Novel Prognostic Marker in Human Prostate Cancer
Open the PDF for The Prolyl Isomerase Pin1 Is a Novel Prognostic Marker in Human Prostate Cancer in another window