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Journal Articles

Abstract 5436: Developing artificial intelligence algorithms to predict response to neoadjuvant chemotherapy in HER2-positive breast cancer

Free
Zhi Huang, Anil V. Parwani, Kun Huang, Zaibo Li
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5436.
https://doi.org/10.1158/1538-7445.AM2023-5436
Published: 04 April 2023
View articletitled, Abstract 5436: Developing artificial intelligence algorithms to predict response to neoadjuvant chemotherapy in HER2-positive breast cancer
Journal Articles

Abstract 886: Fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate on-target off-tumor side effects

Free
Yufei Wang, Alicia Buck, Gabriella Kastrunes, Rabia Abbas, Michael Lynch, Zhou Zhong, Song-My Hoang, Andras Miklosi, Kun Huang, Jae-Won Cho, Marion Grimaud, Cecile Razimbaud, Matthew Chang, Atef Fayed, Audrey Apollon, Nithyassree Murugan, Ze-Hua Li, Tran Thai, Luann Zerefa, Brandon Piel, Elena Ivanova, Amy Cameron, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Yasmin Nabil Laimon, Aseman Bagheri Sheshdeh, Sabina Signoretti, David A. Braun, Catherine J. Wu, Toni K. Choueiri, Jon Wee, Cloud P. Paweletz, Martin Hemberg, Aedin C. Culhane, David A. Barbie, Gordon J. Freeman, Wayne A. Marasco
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 886.
https://doi.org/10.1158/1538-7445.AM2023-886
Published: 04 April 2023
View articletitled, Abstract 886: Fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate on-target off-tumor side effects
Journal Articles

Abstract P5-14-08: Machine learning based histopathology images analysis reveals cancer stemness in TNBC patient with 17p loss

Free
tianhan dong, jiannan liu, yuanzhang Fang, Ziyu Liu, Xiongbin Lu, kun huang
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-14-08.
https://doi.org/10.1158/1538-7445.SABCS22-P5-14-08
Published: 01 March 2023
View articletitled, Abstract P5-14-08: Machine learning based histopathology images analysis reveals cancer stemness in TNBC patient with 17p loss
Journal Articles

Abstract 238: Exhaustive tumor specific antigen detection with RNAseq

Free
Michael Sharpnack, Travis Johnson, Robert Chalkley, Zhi Han, David Carbone, Kun Huang, Kai He
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 238.
https://doi.org/10.1158/1538-7445.AM2021-238
Published: 01 July 2021
View articletitled, Abstract 238: Exhaustive tumor specific antigen detection with RNAseq
Journal Articles

A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer

Free
Jiang Chang, Jianbo Tian, Yang Yang, Rong Zhong, Jiaoyuan Li, Kan Zhai, Juntao Ke, Jiao Lou, Wei Chen, Beibei Zhu, Na Shen, Yi Zhang, Yajie Gong, Ying Zhu, Danyi Zou, Xiating Peng, Kun Huang, Xiaoping Miao
Journal: Cancer Research
Cancer Res (2018) 78 (17): 5164–5172.
https://doi.org/10.1158/0008-5472.CAN-18-0910
Published: 04 September 2018
View articletitled, A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer
Open the PDF for A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer in another window
Includes: Supplementary data
Journal Articles

Mutational Mechanisms That Activate Wnt Signaling and Predict Outcomes in Colorectal Cancer Patients

Free
William Hankey, Michael A. McIlhatton, Kenechi Ebede, Brian Kennedy, Baris Hancioglu, Jie Zhang, Guy N. Brock, Kun Huang, Joanna Groden
Journal: Cancer Research
Cancer Res (2018) 78 (3): 617–630.
https://doi.org/10.1158/0008-5472.CAN-17-1357
Published: 31 January 2018
View articletitled, Mutational Mechanisms That Activate Wnt Signaling and Predict Outcomes in Colorectal Cancer Patients
Open the PDF for Mutational Mechanisms That Activate Wnt Signaling and Predict Outcomes in Colorectal Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Integrative Analysis of Histopathological Images and Genomic Data Predicts Clear Cell Renal Cell Carcinoma Prognosis

Free
Jun Cheng, Jie Zhang, Yatong Han, Xusheng Wang, Xiufen Ye, Yuebo Meng, Anil Parwani, Zhi Han, Qianjin Feng, Kun Huang
Journal: Cancer Research
Cancer Res (2017) 77 (21): e91–e100.
https://doi.org/10.1158/0008-5472.CAN-17-0313
Published: 31 October 2017
View articletitled, Integrative Analysis of Histopathological Images and Genomic Data Predicts Clear Cell Renal Cell Carcinoma Prognosis
Open the PDF for Integrative Analysis of Histopathological Images and Genomic Data Predicts Clear Cell Renal Cell Carcinoma Prognosis in another window
Includes: Supplementary data
Journal Articles

Abstract 5280: A web-based platform for exploring ‘omics and clinical data from healthy breast tissues

Free
Xingyan Kuang, Catalin Marian, Cenny Taslim, Min-Ae Song, Daniel Weng, Jo L. Freudenheim, Theodore Brasky, Kun Huang, Kevin Coombes, Peter G. Shields
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5280.
https://doi.org/10.1158/1538-7445.AM2016-5280
Published: 15 July 2016
View articletitled, Abstract 5280: A web-based platform for exploring ‘omics and clinical data from healthy breast tissues
Journal Articles

Abstract 3971: Genome-wide tissue-based microRNA signature in healthy women predicting breast cancer risk

Free
Cenny Taslim, Daniel Y. Weng, Theodore M. Brasky, Ramona G. Dumitrescu, Kun Huang, Bhaskar V. s. Kallakury, Shiva Krishnan, Adana A. Llanos, Catalin Marian, Sallie S. Schneider, Scott L. Spear, Melissa A. Troester, Jo L. Freudenheim, Susan Geyer, Peter G. Shields
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3971.
https://doi.org/10.1158/1538-7445.AM2015-3971
Published: 01 August 2015
View articletitled, Abstract 3971: Genome-wide tissue-based microRNA signature in healthy women predicting breast cancer risk
Journal Articles

MPHOSPH1: A Potential Therapeutic Target for Hepatocellular Carcinoma

Free
Xinran Liu, Yafan Zhou, Xinyuan Liu, Anlin Peng, Hao Gong, Lizi Huang, Kaige Ji, Robert B. Petersen, Ling Zheng, Kun Huang
Journal: Cancer Research
Cancer Res (2014) 74 (22): 6623–6634.
https://doi.org/10.1158/0008-5472.CAN-14-1279
Published: 13 November 2014
View articletitled, MPHOSPH1: A Potential Therapeutic Target for Hepatocellular Carcinoma
Open the PDF for MPHOSPH1: A Potential Therapeutic Target for Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract B41: Methylome profiling identifies unique patterns of DNA methylation in endometrial cancers

Free
Michael P. Trimarchi, Pearlly S. Yan, Kun Huang, Joanna Groden, Ralf Bundschuh, Paul J. Goodfellow
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): B41.
https://doi.org/10.1158/1538-7445.CEC13-B41
Published: 13 May 2014
View articletitled, Abstract B41: Methylome profiling identifies unique patterns of DNA methylation in endometrial cancers
Journal Articles

Abstract 1984: A novel logistic regression model for microRNA microarray normalization

Free
Bin Wang, Paul Howell, Xiaofeng Wang, Xuemin Qian, Kun Huang, Adam Riker, Jingfang Ju, Yaguang Xi
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1984.
https://doi.org/10.1158/1538-7445.AM10-1984
Published: 15 April 2010
View articletitled, Abstract 1984: A novel logistic regression model for microRNA microarray normalization
Journal Articles

An Ets2-Driven Transcriptional Program in Tumor-Associated Macrophages Promotes Tumor Metastasis

Free
Tahera Zabuawala, David A. Taffany, Sudarshana M. Sharma, Anand Merchant, Brett Adair, Ruchika Srinivasan, Thomas J. Rosol, Soledad Fernandez, Kun Huang, Gustavo Leone, Michael C. Ostrowski
Journal: Cancer Research
Cancer Res (2010) 70 (4): 1323–1333.
https://doi.org/10.1158/0008-5472.CAN-09-1474
Published: 14 February 2010
View articletitled, An Ets2-Driven Transcriptional Program in Tumor-Associated Macrophages Promotes Tumor Metastasis
Open the PDF for An Ets2-Driven Transcriptional Program in Tumor-Associated Macrophages Promotes Tumor Metastasis in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract #3010: Black raspberry modulation of inflammatory gene expression in oral squamous cell carcinoma patients

Free
Jeanette Ferguson, Thomas Knobloch, Christine Sardo, Lana Uhrig, Bruce Casto, Blake Warner, Kun Huang, Gulcin Ozer, David Schuller, Enver Ozer, Amit Agrawal, Christopher Weghorst
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3010.
Published: 01 May 2009
View articletitled, Abstract #3010: Black raspberry modulation of inflammatory gene expression in oral squamous cell carcinoma patients
Journal Articles

Four common gene expression changes across multiple cancers in multiple species

Free
Leszek Rybaczyk, Dorothy Pathak, Lee Cooper, Kristin Circle, Kun Huang
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4266.
Published: 01 May 2008
View articletitled, Four common gene expression changes across multiple cancers in multiple species
Journal Articles

Antibody Targeting of Doxorubicin-loaded Liposomes Suppresses the Growth and Metastatic Spread of Established Human Lung Tumor Xenografts in Severe Combined Immunodeficient Mice

Free
Masahiko Sugano, Nejat K. Egilmez, Sandra J. Yokota, Fang-An Chen, Jennifer Harding, Shi Kun Huang, Richard B. Bankert
Journal: Cancer Research
Cancer Res (2000) 60 (24): 6942–6949.
Published: 01 December 2000
View articletitled, Antibody Targeting of Doxorubicin-loaded Liposomes Suppresses the Growth and Metastatic Spread of Established Human Lung Tumor Xenografts in Severe Combined Immunodeficient Mice
Open the PDF for Antibody Targeting of Doxorubicin-loaded Liposomes Suppresses the Growth and Metastatic Spread of Established Human Lung Tumor Xenografts in Severe Combined Immunodeficient Mice in another window
Journal Articles

Mirovascular Permeability and Interstitial Penetration of Sterically Stabilized (Stealth) Liposomes in a Human Tumor Xenograft

Free
Fan Yuan, Michael Leunig, Shi Kun Huang, David A. Berk, Demetrios Papahadjopoulos, Rakesh K. Jain
Journal: Cancer Research
Cancer Res (1994) 54 (13): 3352–3356.
Published: 01 July 1994
View articletitled, Mirovascular Permeability and Interstitial Penetration of Sterically Stabilized (Stealth) Liposomes in a Human Tumor Xenograft
Open the PDF for Mirovascular Permeability and Interstitial Penetration of Sterically Stabilized (Stealth) Liposomes in a Human Tumor Xenograft in another window
Journal Articles

Liposomes and Hyperthermia in Mice: Increased Tumor Uptake and Therapeutic Efficacy of Doxorubicin in Sterically Stabilized Liposomes

Free
Shi Kun Huang, Paul R. Stauffer, Keelung Hong, John W. H. Guo, Theodore L. Phillips, Anthony Huang, Demetrios Papahadjopoulos
Journal: Cancer Research
Cancer Res (1994) 54 (8): 2186–2191.
Published: 01 April 1994
View articletitled, Liposomes and Hyperthermia in Mice: Increased Tumor Uptake and Therapeutic Efficacy of Doxorubicin in Sterically Stabilized Liposomes
Open the PDF for Liposomes and Hyperthermia in Mice: Increased Tumor Uptake and Therapeutic Efficacy of Doxorubicin in Sterically Stabilized Liposomes in another window
Journal Articles

Pharmacokinetics and Therapeutics of Sterically Stabilized Liposomes in Mice Bearing C-26 Colon Carcinoma

Free
Shi Kun Huang, Eric Mayhew, Syed Gilani, Danilo D. Lasic, Frank J. Martin, Demetrios Papahadjopoulos
Journal: Cancer Research
Cancer Res (1992) 52 (24): 6774–6781.
Published: 01 December 1992
View articletitled, Pharmacokinetics and Therapeutics of Sterically Stabilized Liposomes in Mice Bearing C-26 Colon Carcinoma
Open the PDF for Pharmacokinetics and Therapeutics of Sterically Stabilized Liposomes in Mice Bearing C-26 Colon Carcinoma in another window