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Kristoffer Valerie
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Journal Articles

Editor's Note: mda-9/Syntenin: A Positive Regulator of Melanoma Metastasis

Habib Boukerche, Zao-Zhong Su, Luni Emdad, Patrick Baril, Brigitte Balme, Luc Thomas, Aaron Randolph, Kristoffer Valerie, Devanand Sarkar, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2019) 79 (19): 5127.
https://doi.org/10.1158/0008-5472.CAN-19-2443
Published: 01 October 2019
View article titled, Editor's Note: <em>mda-9</em>/Syntenin: A Positive Regulator of Melanoma Metastasis
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Journal Articles

Abstract 3041: Blood-brain barrier penetrating ATM inhibitor (AZ32) radiosensitises intracranial gliomas in mice

Steve T. Durant, Jeremy Karlin, Kurt Pike, Nicola Colclough, N Mukhopadhyay, S F. Ahmad, J M. Bekta, M Tokarz, Catherine Bardelle, Gareth Hughes, Bhavika Patel, Andrew Thomason, Elaine Cadogan, Ian Barrett, Alan Lau, Martin Pass, Kristoffer Valerie
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3041.
https://doi.org/10.1158/1538-7445.AM2016-3041
Published: 15 July 2016
View article titled, Abstract 3041: Blood-brain barrier penetrating ATM inhibitor (AZ32) radiosensitises intracranial gliomas in mice
Journal Articles

Abstract 4539: Selection of non-phophorylated peptide inhibitors of BRCA1.

E. Railey White, Zhong Ma, David E. Hacker, Jason M. Beckta, Melissa B. Huie, David C. Williams, Kristoffer Valerie, Matthew C. Hartman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4539.
https://doi.org/10.1158/1538-7445.AM2013-4539
Published: 15 April 2013
View article titled, Abstract 4539: Selection of non-phophorylated peptide inhibitors of BRCA1.
Journal Articles

Abstract 1450: Targeting the ATM kinase as a novel strategy for radiosensitizing glioblastoma multiforme in mice

Laura Biddlestone-Thorpe, Sajjad Muhammad, Elizabeth Rosenberg, Sarah E. Golding, Bret R. Adams, Mary Tokarz, Ashraf Khalil, Donna Gilfor, Mark O'Connor, Kristoffer Valerie
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1450.
https://doi.org/10.1158/1538-7445.AM2012-1450
Published: 15 April 2012
View article titled, Abstract 1450: Targeting the ATM kinase as a novel strategy for radiosensitizing glioblastoma multiforme in mice
Journal Articles

Abstract 2638: Association between Adriamycin-induced autophagy and senescence in breast cancer cells

Xu Di, Molly L. Bristol, Kristoffer Valerie, Amy J. Hawkins, David A. Gewirtz
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2638.
https://doi.org/10.1158/1538-7445.AM2011-2638
Published: 15 April 2011
View article titled, Abstract 2638: Association between Adriamycin-induced autophagy and senescence in breast cancer cells
Journal Articles

Abstract 3923: ATM and KAP1 are required for nonhomologous end-joining in transcriptionally active chromatin

Amy J. Hawkins, David E. White, Sarah E. Golding, Konstantin Akopiants, Frank J. Rauscher, Lawrence F. Povirk, Kristoffer Valerie
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3923.
https://doi.org/10.1158/1538-7445.AM10-3923
Published: 15 April 2010
View article titled, Abstract 3923: ATM and KAP1 are required for nonhomologous end-joining in transcriptionally active chromatin
Journal Articles

Oncogenic EGFRvIII upregulates DNA double-strand break repair in human glioma cells

Sarah Golding, Rhiannon Morgan, Lawrence Povirk, Kristoffer Valerie
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1454.
Published: 01 May 2008
View article titled, Oncogenic EGFRvIII upregulates DNA double-strand break repair in human glioma cells
Journal Articles

Initial characterization of a mouse model with a deficiency in tyrosyl-DNA phosphodiesterase

Amy Hawkins, Mark Subler, Konstantin Akopiants, Jenny Wiley, Jolene Windle, Kristoffer Valerie, Lawrence Povirk
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3901.
Published: 01 May 2007
View article titled, Initial characterization of a mouse model with a deficiency in tyrosyl-DNA phosphodiesterase
Journal Articles

The effects of ERB-B1/2 inhibitor, AEE-788 tobacco alkaloid, nicotine, on EGFR expression and phosphorylation and cell growth in U87 malignant glioma cells.

Theodore Chung, William Broaddus, Ashraf Khalil, Asad Khan, Kristoffer Valerie
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): LB-25.
Published: 01 May 2007
View article titled, The effects of ERB-B1/2 inhibitor, AEE-788 tobacco alkaloid, nicotine, on EGFR expression and phosphorylation and cell growth in U87 malignant glioma cells.
Journal Articles

Extracellular Signal-Related Kinase Positively Regulates Ataxia Telangiectasia Mutated, Homologous Recombination Repair, and the DNA Damage Response

Sarah E. Golding, Elizabeth Rosenberg, Steven Neill, Paul Dent, Lawrence F. Povirk, Kristoffer Valerie
Journal: Cancer Research
Cancer Res (2007) 67 (3): 1046–1053.
https://doi.org/10.1158/0008-5472.CAN-06-2371
Published: 05 February 2007
View article titled, Extracellular Signal-Related Kinase Positively Regulates Ataxia Telangiectasia Mutated, Homologous Recombination Repair, and the DNA Damage Response
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Includes: Supplementary data
Journal Articles

N-Glycosylation of MDA-7/IL-24 Is Dispensable for Tumor Cell–Specific Apoptosis and “Bystander” Antitumor Activity

Moira Sauane, Pankaj Gupta, Irina V. Lebedeva, Zao-zhong Su, Devanand Sarkar, Aaron Randolph, Kristoffer Valerie, Rahul V. Gopalkrishnan, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2006) 66 (24): 11869–11877.
https://doi.org/10.1158/0008-5472.CAN-06-1887
Published: 18 December 2006
View article titled, N-Glycosylation of MDA-7/IL-24 Is Dispensable for Tumor Cell–Specific Apoptosis and “Bystander” Antitumor Activity
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Journal Articles

BiP/GRP78 Is an Intracellular Target for MDA-7/IL-24 Induction of Cancer-Specific Apoptosis

Pankaj Gupta, Mark R. Walter, Zao-zhong Su, Irina V. Lebedeva, Luni Emdad, Aaron Randolph, Kristoffer Valerie, Devanand Sarkar, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2006) 66 (16): 8182–8191.
https://doi.org/10.1158/0008-5472.CAN-06-0577
Published: 15 August 2006
View article titled, BiP/GRP78 Is an Intracellular Target for MDA-7/IL-24 Induction of Cancer-Specific Apoptosis
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Includes: Supplementary data
Journal Articles

N-glycosylation of MDA-7/IL-24 is not required for tumor cell-specific apoptosis

Moira Sauane, Zao-Zhong Su, Irina V. Lebedeva, Pankaj Gupta, Aaron Randolph, Kristoffer Valerie, Devanand Sarkar, Rahul V. Gopalkrishnan, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 515.
Published: 15 April 2006
View article titled, N-glycosylation of MDA-7/IL-24 is not required for tumor cell-specific apoptosis
Journal Articles

A novel mechanism for ionizing radiation-induced radio-resistance of tumor cells involving SHP2 and nuclear localization of EGFR

Lisa-Marie Sturla, Michael S. Alexander, Kristoffer Valerie, Ross B. Mikkelsen
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1029.
Published: 15 April 2006
View article titled, A novel mechanism for ionizing radiation-induced radio-resistance of tumor cells involving SHP2 and nuclear localization of EGFR
Journal Articles

The endoplasmic reticulum (ER) resident protein BiP/GRP78 is an intracellular target for induction of cancer-specific apoptosis by mda-7/IL-24

Pankaj Gupta, Zao-Zhong Su, Irina V. Lebedeva, Aaron Randolph, Kristoffer Valerie, Mark R. Walter, Devanand Sarkar, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 512.
Published: 15 April 2006
View article titled, The endoplasmic reticulum (ER) resident protein BiP/GRP78 is an intracellular target for induction of cancer-specific apoptosis by mda-7/IL-24
Journal Articles

Molecular Target-Based Therapy of Pancreatic Cancer

Irina V. Lebedeva, Devanand Sarkar, Zao-Zhong Su, Rahul V. Gopalkrishnan, Mohammad Athar, Aaron Randolph, Kristoffer Valerie, Paul Dent, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2006) 66 (4): 2403–2413.
https://doi.org/10.1158/0008-5472.CAN-05-3510
Published: 17 February 2006
View article titled, Molecular Target-Based Therapy of Pancreatic Cancer
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Journal Articles

Activation of the Nuclear Factor κB Pathway by Astrocyte Elevated Gene-1: Implications for Tumor Progression and Metastasis

Luni Emdad, Devanand Sarkar, Zao-zhong Su, Aaron Randolph, Habib Boukerche, Kristoffer Valerie, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2006) 66 (3): 1509–1516.
https://doi.org/10.1158/0008-5472.CAN-05-3029
Published: 01 February 2006
View article titled, Activation of the Nuclear Factor κB Pathway by Astrocyte Elevated Gene-1: Implications for Tumor Progression and Metastasis
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Journal Articles

mda-9/Syntenin: A Positive Regulator of Melanoma Metastasis

Habib Boukerche, Zao-zhong Su, Luni Emdad, Patrick Baril, Brigitte Balme, Luc Thomas, Aaron Randolph, Kristoffer Valerie, Devanand Sarkar, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2005) 65 (23): 10901–10911.
https://doi.org/10.1158/0008-5472.CAN-05-1614
Published: 01 December 2005
View article titled, <em>mda-9</em>/Syntenin: A Positive Regulator of Melanoma Metastasis
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Journal Articles

Targeted Virus Replication Plus Immunotherapy Eradicates Primary and Distant Pancreatic Tumors in Nude Mice

Devanand Sarkar, Zao-zhong Su, Nicolaq Vozhilla, Eun Sook Park, Aaron Randolph, Kristoffer Valerie, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2005) 65 (19): 9056–9063.
https://doi.org/10.1158/0008-5472.CAN-05-1261
Published: 03 October 2005
View article titled, Targeted Virus Replication Plus Immunotherapy Eradicates Primary and Distant Pancreatic Tumors in Nude Mice
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Journal Articles

Radiosensitivity and deficiency in processing of 3’-phosphoglycolate-terminated DNA double-strand breaks in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)

Haritha Tatavarthi, Tong Zhou, Jae W. Lee, Kristoffer Valerie, James R. Lupski, Susan P. Lees-Miller, Lawrence F. Povirk
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 469.
Published: 01 May 2005
View article titled, Radiosensitivity and deficiency in processing of 3’-phosphoglycolate-terminated DNA double-strand breaks in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)