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Kris Thielemans
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Journal Articles

Abstract CT221: Mutanome engineered RNA immuno-therapy (MERIT) for patients with triple negative breast cancer (TNBC)

Ludwig Heesen, Katrin Frenzel, Stefanie Bolte, Valesca Bukur, Mustafa Diken, Evelyna Derhovanessian, Sebastian Kreiter, Andreas N. Kuhn, Klaus Kühlcke, Martin Löwer, Henrik Lindman, Steve Pascolo, Marcus Schmidt, Andreas Schneeweiss, Tobias Sjöblom, Kris Thielemans, Laurence Zitvogel, Özlem Türeci, Ugur Sahin
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT221.
https://doi.org/10.1158/1538-7445.AM2019-CT221
Published: 01 July 2019
View article titled, Abstract CT221: Mutanome engineered RNA immuno-therapy (MERIT) for patients with triple negative breast cancer (TNBC)
Journal Articles

Abstract CT020: MERIT: introducing individualized cancer vaccines for the treatment of TNBC - a phase I trial

Sandra Heesch, Valesca Bukur, Janina Buck, Jan Diekmann, Mustafa Diken, Kerstin Ewen, Heinrich Haas, Alexandra Kemmer-Brueck, Björn-Philipp Kloke, Sebastian Kreiter, Andreas N. Kuhn, Klaus Kuehlcke, Martin Loewer, Anna Paruzynski, Kathrin Schultheiß, Doreen Schwarck, Marcus Schmidt, Fabrice André, Jacques De Greve, Thomas Kuendig, Henrik Lindman, Steve Pascolo, Tobias Sjöblom, Kris Thielemans, Laurence Zitvogel, Özlem Türeci, Ugur Sahin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): CT020.
https://doi.org/10.1158/1538-7445.AM2016-CT020
Published: 15 July 2016
View article titled, Abstract CT020: MERIT: introducing individualized cancer vaccines for the treatment of TNBC - a phase I trial
Journal Articles

Abstract CT201: The Mutanome Engineered RNA Immuno-Therapy (MERIT) project

Sandra Heesch, Cedrik M. Britten, Valesca Bukur, Janina Buck, John Castle, Jan Diekmann, Mustafa Diken, Katrin Frenzel, Sebastian Kreiter, Andreas N. Kuhn, Klaus Kuehlcke, Martin Loewer, Heinrich Haas, Alexandra Kemmer-Brueck, Bjoern-Philipp Kloke, Burkhard Otte, Anna Paruzynski, Sebastian Petri, Doreen Schwarck-Kokarakis, Marcus Schmidt, Fabrice André, Jacques De Greve, Thomas Kuendig, Henrik Lindman, Steve Pascolo, Tobias Sjöblom, Kris Thielemans, Laurence Zitvogel, Oezlem Tuereci, Ugur Sahin
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT201.
https://doi.org/10.1158/1538-7445.AM2015-CT201
Published: 01 August 2015
View article titled, Abstract CT201: The Mutanome Engineered RNA Immuno-Therapy (MERIT) project
Journal Articles

Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy

Sandra Van Lint, Cleo Goyvaerts, Sarah Maenhout, Lode Goethals, Aurélie Disy, Daphné Benteyn, Joeri Pen, Aude Bonehill, Carlo Heirman, Karine Breckpot, Kris Thielemans
Journal: Cancer Research
Cancer Res (2012) 72 (7): 1661–1671.
https://doi.org/10.1158/0008-5472.CAN-11-2957
Published: 01 April 2012
View article titled, Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy
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Journal Articles

Proinflammatory Characteristics of SMAC/DIABLO-Induced Cell Death in Antitumor Therapy

Perpetua U. Emeagi, Sandra Van Lint, Cleo Goyvaerts, Sarah Maenhout, Anje Cauwels, Iain A. McNeish, Tomas Bos, Carlo Heirman, Kris Thielemans, Joeri L. Aerts, Karine Breckpot
Journal: Cancer Research
Cancer Res (2012) 72 (6): 1342–1352.
https://doi.org/10.1158/0008-5472.CAN-11-2400
Published: 14 March 2012
View article titled, Proinflammatory Characteristics of SMAC/DIABLO-Induced Cell Death in Antitumor Therapy
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Includes: Supplementary data
Journal Articles

A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice

Nathalie Demotte, Grégoire Wieërs, Patrick Van Der Smissen, Muriel Moser, Christopher Schmidt, Kris Thielemans, Jean-Luc Squifflet, Birgit Weynand, Javier Carrasco, Christophe Lurquin, Pierre J. Courtoy, Pierre van der Bruggen
Journal: Cancer Research
Cancer Res (2010) 70 (19): 7476–7488.
https://doi.org/10.1158/0008-5472.CAN-10-0761
Published: 29 September 2010
View article titled, A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice
Open the PDF for A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice in another window
Includes: Supplementary data
Journal Articles

The CD4+ T-Cell Response of Melanoma Patients to a MAGE-A3 Peptide Vaccine Involves Potential Regulatory T Cells

Violaine François, Sabrina Ottaviani, Nicolina Renkvist, Julie Stockis, Gerold Schuler, Kris Thielemans, Didier Colau, Marie Marchand, Thierry Boon, Sophie Lucas, Pierre van der Bruggen
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4335–4345.
https://doi.org/10.1158/0008-5472.CAN-08-3726
Published: 15 May 2009
View article titled, The CD4<sup>+</sup> T-Cell Response of Melanoma Patients to a MAGE-A3 Peptide Vaccine Involves Potential Regulatory T Cells
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Includes: Supplementary data
Journal Articles

Abstract #716: T-cell responses to therapeutic vaccination with an autologous TriMix-dendritic cell vaccine in advanced melanoma patients

Kris Thielemans
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 716.
Published: 01 May 2009
View article titled, Abstract #716: T-cell responses to therapeutic vaccination with an autologous TriMix-dendritic cell vaccine in advanced melanoma patients
Journal Articles

Functions of Anti-MAGE T-Cells Induced in Melanoma Patients under Different Vaccination Modalities

Thierry Connerotte, Aline Van Pel, Danièle Godelaine, Eric Tartour, Beatrice Schuler-Thurner, Sophie Lucas, Kris Thielemans, Gerold Schuler, Pierre G. Coulie
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3931–3940.
https://doi.org/10.1158/0008-5472.CAN-07-5898
Published: 15 May 2008
View article titled, Functions of Anti-MAGE T-Cells Induced in Melanoma Patients under Different Vaccination Modalities
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Journal Articles

Efficient Presentation of Known HLA Class II-restricted MAGE-A3 Epitopes by Dendritic Cells Electroporated with Messenger RNA Encoding an Invariant Chain with Genetic Exchange of Class II-associated Invariant Chain Peptide

Aude Bonehill, Carlo Heirman, Sandra Tuyaerts, Annelies Michiels, Yi Zhang, Pierre van der Bruggen, Kris Thielemans
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5587–5594.
Published: 18 September 2003
View article titled, Efficient Presentation of Known HLA Class II-restricted MAGE-A3 Epitopes by Dendritic Cells Electroporated with Messenger RNA Encoding an Invariant Chain with Genetic Exchange of Class II-associated Invariant Chain Peptide
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Journal Articles

A MAGE-A3 Peptide Presented by HLA-DP4 Is Recognized on Tumor Cells by CD4+ Cytolytic T Lymphocytes

Erwin S. Schultz, Bernard Lethé, César L. Cambiaso, Jacques Van Snick, Pascal Chaux, Jurgen Corthals, Carlo Heirman, Kris Thielemans, Thierry Boon, Pierre van der Bruggen
Journal: Cancer Research
Cancer Res (2000) 60 (22): 6272–6275.
Published: 15 November 2000
View article titled, A MAGE-A3 Peptide Presented by HLA-DP4 Is Recognized on Tumor Cells by CD4<sup>+</sup> Cytolytic T Lymphocytes
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Journal Articles

Expression of B7-1 by Highly Metastatic Mouse T Lymphomas Induces Optimal Natural Killer Cell-mediated Cytotoxicity

Anja B. Geldhof, Geert Raes, Marleen Bakkus, Sophie Devos, Kris Thielemans, Patrick De Baetselier
Journal: Cancer Research
Cancer Res (1995) 55 (13): 2730–2733.
Published: 01 July 1995
View article titled, Expression of B7-1 by Highly Metastatic Mouse T Lymphomas Induces Optimal Natural Killer Cell-mediated Cytotoxicity
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Journal Articles

Role of T-Cell Subsets in the Bispecific Antibody (Anti-Idiotype × Anti-CD3) Treatment of the BCL1 Lymphoma

Christian Demanet, Jan Brissinck, Oberdan Leo, Muriel Moser, Kris Thielemans
Journal: Cancer Research
Cancer Res (1994) 54 (11): 2973–2978.
Published: 01 June 1994
View article titled, Role of T-Cell Subsets in the Bispecific Antibody (Anti-Idiotype × Anti-CD3) Treatment of the BCL<sub>1</sub> Lymphoma
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