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Konstantinos V. Floros
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Journal Articles

Abstract 7071: Pharmacological targeting of SUMOylation leads to cBAF complex stabilization and disruption of the synovial sarcoma signature

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Konstantinos V. Floros, Jinxiu Li, Jane L. Roberts, Richard Kurupi, Carter K. Fairchild, Bin Hu, Yanli Xing, Krista M. Dalton, Sosipatros A. Boikos, Angeliki M. Stamatouli, Mikhail G. Dozmorov, Jennifer E. Koblinski, Kevin B. Jones, Senthil K. Radhakrishnan, Anthony C. Faber
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7071.
https://doi.org/10.1158/1538-7445.AM2024-7071
Published: 22 March 2024
View articletitled, Abstract 7071: Pharmacological targeting of SUMOylation leads to cBAF complex stabilization and disruption of the synovial sarcoma signature
Journal Articles

Abstract 362: MYCN-amplified neuroblastoma is addicted to iron and vulnerable to ferroptosis

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Konstantinos V. Floros, Mia O. Johnson-Berro, Richard Kurupi, Carter K. Fairchild, Krista Dalton, Bin Hu, Madhavi Puchalapalli, Mikhail G. Dozmorov, Jennifer E. Koblinski, James A. Olzmann, Lauren A. Cowart, Anthony C. Faber
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 362.
https://doi.org/10.1158/1538-7445.AM2022-362
Published: 15 June 2022
View articletitled, Abstract 362: MYCN-amplified neuroblastoma is addicted to iron and vulnerable to ferroptosis
Journal Articles

MYCN-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis

Free
Konstantinos V. Floros, JinYang Cai, Sheeba Jacob, Richard Kurupi, Carter K. Fairchild, Mayuri Shende, Colin M. Coon, Krista M. Powell, Benjamin R. Belvin, Bin Hu, Madhavi Puchalapalli, Sivapriya Ramamoorthy, Kimberly Swift, Janina P. Lewis, Mikhail G. Dozmorov, John Glod, Jennifer E. Koblinski, Sosipatros A. Boikos, Anthony C. Faber
Journal: Cancer Research
Cancer Res (2021) 81 (7): 1896–1908.
https://doi.org/10.1158/0008-5472.CAN-20-1641
Published: 01 April 2021
View articletitled, MYCN-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis
Open the PDF for MYCN-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis in another window
Includes: Supplementary data
Journal Articles

Abstract PO-024: Catastrophic ATP loss underlines a metabolic combination therapy tailored for MYCN-amplified neuroblastoma

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Krista M. Powell, Timonthy L. Lochmann, Konstantinos V. Floros, Marissa L. Calbert, Richard Kurupi, Giovanna T. Stein, Joseph McClanaghan, Ellen Murchie, Regina K. Egan, Patricia Greninger, Mikhail Dozmorov, Sivapriya Ramamoorthy, Madhavi Puchalapalli, Bin Hu, Lisa Shock, Jennifer Koblisnski, John Glod, Sosipatros A. Boikos, Cyril H. Benes, Anthony C. Faber
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-024.
https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-024
Published: 02 December 2020
View articletitled, Abstract PO-024: Catastrophic ATP loss underlines a metabolic combination therapy tailored for MYCN-amplified neuroblastoma
Journal Articles

Investigating New Mechanisms of Acquired Resistance to Targeted Therapies: If You Hit Them Harder, Do They Get Up Differently?

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Konstantinos V. Floros, Aaron N. Hata, Anthony C. Faber
Journal: Cancer Research
Cancer Res (2020) 80 (1): 25–26.
https://doi.org/10.1158/0008-5472.CAN-19-3405
Published: 03 January 2020
View articletitled, Investigating New Mechanisms of Acquired Resistance to Targeted Therapies: If You Hit Them Harder, Do They Get Up Differently?
Open the PDF for Investigating New Mechanisms of Acquired Resistance to Targeted Therapies: If You Hit Them Harder, Do They Get Up Differently? in another window
Journal Articles

Abstract 3082: Deficient NOXA in HER2-amplified breast cancer drives kinase inhibitor resistance

Free
Konstantinos V. Floros, Kyung-A Song, Timothy L. Lochmann, Mark T. Hughes, Daniel A. Heisey, Hisashi Harada, Bin Hu, Jennifer Koblinski, Andrew J. Souers, Joel D. Leverson, Anthony C. Faber
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3082.
https://doi.org/10.1158/1538-7445.AM2017-3082
Published: 01 July 2017
View articletitled, Abstract 3082: Deficient NOXA in HER2-amplified breast cancer drives kinase inhibitor resistance