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Journal Articles

Abstract CT034: Phase II study of SCC244 in NSCLC patients harboring MET exon 14 skipping (METex14) mutations (GLORY study)

Shun Lu, Yongfeng Yu, Jianya Zhou, Koichi Goto, Xingya Li, Jun Sakakibara-Konishi, Kazumi Nishino, Tanaka Kentaro, Lin Wu, Xuhong Min, Wei Zhang, Dingzhi Huang, Yongqian Shu, Chengzhi Zhou, Min Li, Xiaorong Dong, Chong Bai, Lu Li, Jiuwei Cui, Li Zhang, Lejie Cao, Xiaoling Li, AiMin Zang, Haruki Kobayashi, Yiping Zhang, Yan Yu, Xiuwen Wang, Terufumi Kato, Shoichiro Yamamoto, Yuki Shinno, Xiaoyan Lin, Yanqiu Zhao, Yanping Hu, Qitao Yu, Ziping Wang, Masahiro Kodani, Jian Fang, Jialei Wang, Meiqi Shi, Diansheng Zhong, Wen Dong, Hiroshi Tanaka, Yasuto Yoneshima, Minghui Sun, Jun Zhou, Qiuxia Wu, Meng Li
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT034.
DOI: https://doi.org/10.1158/1538-7445.AM2022-CT034
Published: 15 June 2022
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Journal Articles

Abstract CT184: Emerging evidence of activity of BLU-945 in patients with advanced EGFR-mutant NSCLC utilizing circulating tumor DNA (ctDNA) in the phase 1/2 SYMPHONY study

Elaine Shum, Yasir Elamin, Karen L. Reckamp, Zofia Piotrowska, Julia Rotow, Daniel S. Tan, Koichi Goto, Jagan Parepally, Faris Albayya, Melinda Louie-Gao, Renata Sawtell, Alena Zalutskaya, David Spigel
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT184.
DOI: https://doi.org/10.1158/1538-7445.AM2022-CT184
Published: 15 June 2022
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Journal Articles

Abstract 5351: LTK mutations responsible for resistance to lorlatinib in non-small cell lung cancer harboring CLIP1-LTK fusion

Shunta Mori, Hiroki Izumi, Jie Liu, Kosuke Tanaka, Shogo Kumagai, Takuma Hayashida, Yosuke Kagawa, Yuji Shibata, Shingo Matumoto, Koichi Goto, Susumu Kobayashi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5351.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5351
Published: 15 June 2022
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Journal Articles

Abstract 5238: CLIP1-LTK: A novel druggable gene fusion in non-small cell lung cancer

Hiroki Izumi, Shingo Matsumoto, Jie Liu, Kosuke Tanaka, Shunta Mori, Shogo Kumagai, Takuma Hayashida, Yuji Shibata, Saori Takata, Eriko Tabata, Haruyasu Murakami, Reiko Taki, Satoshi Hara, Tomohiro Sakamoto, Koichi Goto, Susumu S. Kobayashi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5238.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5238
Published: 15 June 2022
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Journal Articles

Single-Cell Analyses Reveal Diverse Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer

Yukie Kashima, Daisuke Shibahara, Ayako Suzuki, Kyoko Muto, Ikei S. Kobayashi, David Plotnick, Hibiki Udagawa, Hiroki Izumi, Yuji Shibata, Kosuke Tanaka, Masanori Fujii, Akihiro Ohashi, Masahide Seki, Koichi Goto, Katsuya Tsuchihara, Yutaka Suzuki, Susumu S. Kobayashi
Journal: Cancer Research
Cancer Res (2021) 81 (18): 4835–4848.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-2811
Published: 15 September 2021
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Includes: Supplementary data
Journal Articles

Abstract CT106: Phase I/II study of osimertinib in EGFR exon 20 insertion mutations in non-small cell lung cancer patients: AEX20

Eiki Ichihara, Hiroyuki Yasuda, Yuta Takashima, Yoshitaka Zenke, Shinji Takeuchi, Masahiro Morise, Katsuyuki Hotta, Mineyoshi Sato, Shingo Matsumoto, Azusa Tanimoto, Reiko Matsuzawa, Katsuyuki Kiura, Hideki Terai, Shinnosuke Ikemura, Koichi Goto, Kenzo Soejima
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT106.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT106
Published: 01 July 2021
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Journal Articles

Abstract 2052: Tumor mutation burden as a biomarker of relapse free survival of non-squamous non-small cell lung cancer treated with PEM/CDDP in adjuvant setting (the JIPANG-TR)

Masahiro Tsuboi, Kazuto Nishio, Kazuko Sakai, Hirotsugu Kenmotsu, Takeharu Yamanaka, Toshiaki Takahashi, Koichi Goto, Haruko Daga, Norihiko Ikeda, Takashi Seto, Shinichi Toyooka, Hiroshi Date, Tetsuya Mitsudomi, Isamu Okamoto, Hideo Saka, Hiroaki Okamoto, Yuichi Takiguchi, Nobuyuki Yamamoto
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2052.
DOI: https://doi.org/10.1158/1538-7445.AM2020-2052
Published: 15 August 2020
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Journal Articles

Abstract 1329: Preclinical evaluation of TAS6417 as a highly effective, pan-mutation-selective EGFR tyrosine kinase inhibitor

Hibiki Udagawa, Shinichi Hasako, Akihiro Ohashi, Naomi Abe, Tomonori Haruma, Toshiharu Komori, Miki Terasaka, Ryoto Fujita, Kaoru Funabashi, Hiroyuki Yasuda, Kazutaka Miyadera, Koichi Goto, Daniel B. Costa, Susumu S. Kobayashi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1329.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1329
Published: 01 July 2019
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Journal Articles

Abstract 4919: Required numbers of biopsy samples and tumor cells for the assessment of PD-L1 expression to predict a response to nivolumab treatment in patients with NSCLC

Jun Sato, Tomoyuki Naito, Hibiki Udagawa, Hidehito Horinouchi, Shuji Murakami, Yasushi Goto, Shintaro Kanda, Yutaka Fujiwara, Noboru Yamamoto, Yuichiro Ohe, Yoshitaka Zenke, Keisuke Kirita, Shingo Matsumoto, Kiyotaka Yoh, Seiji Niho, Noriko Motoi, Genichiro Ishii, Koichi Goto
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4919.
DOI: https://doi.org/10.1158/1538-7445.AM2019-4919
Published: 01 July 2019
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Journal Articles

Abstract 4920: A status of re-biopsy for non-small-cell lung cancer patients after first EGFR-TKI failure and incidence of T790M mutation

Tetsuya Sakai, Hibiki Udagawa, Yoshitaka Zenke, Keisuke Kirita, Shigeki Umemura, Shingo Matsumoto, Kiyotaka Yoh, Seiji Niho, Genichiro Ishii, Koichi Goto
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4920.
DOI: https://doi.org/10.1158/1538-7445.AM2019-4920
Published: 01 July 2019
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Journal Articles

Abstract 3932: Metabolic biomarkers predict the sensitivity to phosphatidylinositol 3-kinase pathway inhibitor in small-cell lung carcinoma

Shigeki Umemura, Hideki Makinoshima, Genichiro Ishii, Takehiko Sasaki, Hiroyasu Esumi, Koichi Goto, Katsuya Tsuchihara
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3932.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3932
Published: 01 July 2018
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Journal Articles

Abstract 918: A secondary RET mutation allosterically conferring resistance to vandetanib

Takashi Nakaoku, Takashi Kohno, Mitsugu Araki, Seiji Nino, Rakhee Chauhan, Phillip P. Knowles, Katsuya Tsuchihara, Shingo Matsumoto, Yoko Shimada, Sachiyo Mimaki, Genichiro Ishii, Hitoshi Ichikawa, Yasushi Okuno, Kiyotaka Yoh, Neil Q. McDonald, Koichi Goto
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 918.
DOI: https://doi.org/10.1158/1538-7445.AM2018-918
Published: 01 July 2018
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Journal Articles

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma

Hideki Makinoshima, Shigeki Umemura, Ayako Suzuki, Hiroki Nakanishi, Ami Maruyama, Hibiki Udagawa, Sachiyo Mimaki, Shingo Matsumoto, Seiji Niho, Genichiro Ishii, Masahiro Tsuboi, Atsushi Ochiai, Hiroyasu Esumi, Takehiko Sasaki, Koichi Goto, Katsuya Tsuchihara
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (9): 2179–2190.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-2109
Published: 30 April 2018
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Includes: Supplementary data
Journal Articles

Abstract 4111: EGFR wild type allele amplification induces acquired resistance to mutation-specific EGFR tyrosine kinase inhibitors in non-small cell lung cancer cells

Keigo Kobayashi, Shigenari Nukaga, Hiroyuki Yasuda, Keita Masuzawa, Jyunko Hamamoto, Ichiro Kawada, Katsuhiko Naoki, Sachiyo Mimaki, Shingo Matsumoto, Koichi Goto, Katsuya Tsuchihara, Tomoko Betsuyaku, Kenzo Soejima
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4111.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4111
Published: 01 July 2017
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Journal Articles

Amplification of EGFR Wild-Type Alleles in Non–Small Cell Lung Cancer Cells Confers Acquired Resistance to Mutation-Selective EGFR Tyrosine Kinase Inhibitors

Shigenari Nukaga, Hiroyuki Yasuda, Katsuya Tsuchihara, Junko Hamamoto, Keita Masuzawa, Ichiro Kawada, Katsuhiko Naoki, Shingo Matsumoto, Sachiyo Mimaki, Shinnosuke Ikemura, Koichi Goto, Tomoko Betsuyaku, Kenzo Soejima
Journal: Cancer Research
Cancer Res (2017) 77 (8): 2078–2089.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-2359
Published: 13 April 2017
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Includes: Supplementary data
Journal Articles

Abstract 5004: Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: A comparative analysis with adenocarcinoma and squamous cell carcinoma

Yuki Matsumura, Shigeki Umemura, Genichiro Ishii, Koji Tsuta, Shingo Mastsumoto, Keiju Aokage, Tomoyuki Hishida, Junji Yoshida, Yuichiro Ohe, Hiroyuki Suzuki, Atsushi Ochiai, Koichi Goto, Kanji Nagai, Katsuya Tsuchihara
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5004.
DOI: https://doi.org/10.1158/1538-7445.AM2015-5004
Published: 01 August 2015
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Journal Articles

Abstract 1214: RET fusion gene: translation to the therapy of lung adenocarcinoma.

Takashi Kohno, Hitoshi Ichikawa, Koji Tsuta, Tatsuji Mizukami, Yoko Shimada, Mamoru Kato, Hiromi Sakamoto, Katsuya Tsuchihara, Shun-ichi Watanabe, Hiroshi Nokihara, Koichi Goto, Jun Yokota, Teruhiko Yoshida, Tatsuhiro Shibata
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1214.
DOI: https://doi.org/10.1158/1538-7445.AM2013-1214
Published: 15 April 2013
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