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Journal Articles

Ralph A. Reisfeld, PhD: In Memoriam (1926–2020)

James P. Allison, Edward Barker, Jürgen C. Becker, Thomas F. Bumol, David Cheresh, Bill Church, Soldano Ferrone, Darrell R. Galloway, Martin Giedlin, Stephen Gillies, Rupert Handgretinger, John R. Harper, Kohzoh Imai, Barry Kahan, Ruth Ladenstein, Debbie Liao, Holger N. Lode, Hans Loibner, Yun-Ping Luo, Barbara M. Mueller, AhKau Ng, Andreas Niethammer, Michele Pellegrino, Ursula Pertl, Vito Quaranta, Carlo Russo, Helen Sabzevari, Martin Schrappe, Gregor Schulz, Paul Sondel, Andreas Stahl, Argyrios Theophilopoulos, Nissi Varki, Leslie Walker, Barry Wilson, Wolfgang Wrasidlo, Ursula Wargalla-Plate, Rong Xiang, Alice Yu, He Zhou
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1429–1430.
https://doi.org/10.1158/0008-5472.CAN-21-0450
Published: 15 March 2021
View articletitled, Ralph A. Reisfeld, PhD: In Memoriam (1926–2020)
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Journal Articles

Abstract 1449: The valuable experimental model system “Cancer Xenopatient” established in NOG mice

Tsuyoshi Chijiwa, Kenji Kawai, Akira Noguchi, Hidemitsu Sato, Akimune Hayashi, Haruhiko Cho, Manabu Shiozawa, Takeshi Kishida, Soichiro Morinaga, Tomoyuki Yokose, Makoto Katayama, Nobuo Takenaka, Hiroshi Suemizu, Roppei Yamada, Yoshiyasu Nakamura, Yasuo Takano, Kohzoh Imai, Yohei Miyagi, Masato Nakamura
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1449.
https://doi.org/10.1158/1538-7445.AM2015-1449
Published: 01 August 2015
View articletitled, Abstract 1449: The valuable experimental model system “Cancer Xenopatient” established in NOG mice
Journal Articles

Abstract 867: IGF-I receptor targeting therapy for esophageal carcinomas.

Yasushi Adachi, Hiroyuki Yamamoto, Hirokazu Ohashi, Yasutaka Matsunaga, Katsuhiko Nosho, Hiromu Suzuki, Hiroaki Taniguchi, Yoshiaki Arimura, Takao Endo, Yasuo Kato, Kohzoh Imai, David P. Carbone, Yasushisa Shinomura
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 867.
https://doi.org/10.1158/1538-7445.AM2013-867
Published: 15 April 2013
View articletitled, Abstract 867: IGF-I receptor targeting therapy for esophageal carcinomas.
Journal Articles

Abstract 1171: Identification of p53 target genes by ChIP-Seq and transcriptome analysis combined with genome-wide p53-binding motif analysis in silico

Masashi Idogawa, Yasushi Sasaki, Yasuhisa Shinomura, Kohzoh Imai, Takashi Tokino
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1171.
https://doi.org/10.1158/1538-7445.AM2012-1171
Published: 15 April 2012
View articletitled, Abstract 1171: Identification of p53 target genes by ChIP-Seq and transcriptome analysis combined with genome-wide p53-binding motif analysis in silico
Journal Articles

Abstract LB-471: Upregulation of miR-196a and HOTAIR is associated with the malignancy of gastrointestinal stromal tumors

Hiromu Suzuki, Masanori Nojima, Reo Maruyama, Eiichiro Yamamoto, Kohzoh Imai, Yasuhisa Shinomura
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-471.
https://doi.org/10.1158/1538-7445.AM2012-LB-471
Published: 15 April 2012
View articletitled, Abstract LB-471: Upregulation of miR-196a and HOTAIR is associated with the malignancy of gastrointestinal stromal tumors
Journal Articles

Abstract 948: IGF-I receptor expression is associated with stage and has therapeutic activity in human biliary tract cancers

Yasushi Adachi, Hiroyuki Yamamoto, Hirokazu Ohashi, Hiroaki Taniguchi, Katsuhiko Nosho, Hiromu Suzuki, Yoshiaki Arimura, Takao Endo, Kohzoh Imai, David P. Carbone, Yasuhisa Shinomura
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 948.
https://doi.org/10.1158/1538-7445.AM2012-948
Published: 15 April 2012
View articletitled, Abstract 948: IGF-I receptor expression is associated with stage and has therapeutic activity in human biliary tract cancers
Journal Articles

Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors

Takeshi Niinuma, Hiromu Suzuki, Masanori Nojima, Katsuhiko Nosho, Hiroyuki Yamamoto, Hiroyuki Takamaru, Eiichiro Yamamoto, Reo Maruyama, Takayuki Nobuoka, Yasuaki Miyazaki, Toshirou Nishida, Takeo Bamba, Tatsuo Kanda, Yoichi Ajioka, Takahiro Taguchi, Satoshi Okahara, Hiroaki Takahashi, Yasunori Nishida, Masao Hosokawa, Tadashi Hasegawa, Takashi Tokino, Koichi Hirata, Kohzoh Imai, Minoru Toyota, Yasuhisa Shinomura
Journal: Cancer Research
Cancer Res (2012) 72 (5): 1126–1136.
https://doi.org/10.1158/0008-5472.CAN-11-1803
Published: 01 March 2012
View articletitled, Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors
Open the PDF for Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors in another window
Includes: Supplementary data
Journal Articles

Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer

Hiromu Suzuki, Shintaro Takatsuka, Hirofumi Akashi, Eiichiro Yamamoto, Masanori Nojima, Reo Maruyama, Masahiro Kai, Hiro-o Yamano, Yasushi Sasaki, Takashi Tokino, Yasuhisa Shinomura, Kohzoh Imai, Minoru Toyota
Journal: Cancer Research
Cancer Res (2011) 71 (17): 5646–5658.
https://doi.org/10.1158/0008-5472.CAN-11-1076
Published: 30 August 2011
View articletitled, Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Abstract 5405: Apoptosis induction in cancer cells by the simultaneous transduction of p53 and artificial miRNAs based on the screening of genome-wide shRNA library

Masashi Idogawa, Yasushi Sasaki, Lisa Kashima, Yasuhisa Shinomura, Kohzoh Imai, Takashi Tokino
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5405.
https://doi.org/10.1158/1538-7445.AM2011-5405
Published: 15 April 2011
View articletitled, Abstract 5405: Apoptosis induction in cancer cells by the simultaneous transduction of p53 and artificial miRNAs based on the screening of genome-wide shRNA library
Journal Articles

Abstract 3954: Identification of microRNAs epigenetically silenced in bladder cancer

Takashi Shimizu, Hiromu Suzuki, Hiroshi Kitamura, Eiichiro Yamamoto, Kohzoh Imai, Taiji Tsukamoto, Minoru Toyota
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3954.
https://doi.org/10.1158/1538-7445.AM2011-3954
Published: 15 April 2011
View articletitled, Abstract 3954: Identification of microRNAs epigenetically silenced in bladder cancer
Journal Articles

Abstract 632: The efficacy of IGF-I receptor monoclonal antibody for human gastrointestinal carcinomas is independent for mutation status of k-ras

Yasushi Adachi, Hiroyuki Yamamoto, Masanori Ii, Hua Li, Hirokazu Ohashhi, Yoshiaki Arimura, Takao Endo, Kohzoh Imai, David P. Carbone, Yasushisa Shinomura
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 632.
https://doi.org/10.1158/1538-7445.AM2011-632
Published: 15 April 2011
View articletitled, Abstract 632: The efficacy of IGF-I receptor monoclonal antibody for human gastrointestinal carcinomas is independent for mutation status of k-ras
Journal Articles

Abstract 4945: Epigenetic silencing of microRNA-34b/c in human gastric cancer

Hiromu Suzuki, Eiichiro Yamamoto, Masanori Nojima, Takashi Tokino, Kohzoh Imai, Minoru Toyota, Yasuhisa Shinomura
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4945.
https://doi.org/10.1158/1538-7445.AM10-4945
Published: 15 April 2010
View articletitled, Abstract 4945: Epigenetic silencing of microRNA-34b/c in human gastric cancer
Journal Articles

Abstract 595: Single adenovirus-mediated simultaneous expression of p53 and the artificial microRNAs targeting anti-apoptotic p53 target genes

Masashi Idogawa, Yasushi Sasaki, Kohzoh Imai, Yasuhisa Shinomura, Takashi Tokino
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 595.
https://doi.org/10.1158/1538-7445.AM10-595
Published: 15 April 2010
View articletitled, Abstract 595: Single adenovirus-mediated simultaneous expression of p53 and the artificial microRNAs targeting anti-apoptotic p53 target genes
Journal Articles

Abstract 169: The origin of colorectal cancer with CpG island methylator phenotype

Minoru Toyota, Eiichiro Yamamoto, Hiromu Suzuki, Seiko Kamimae, Hiro-o Yamano, Yasuhisa Shinomura, Kohzoh Imai
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 169.
https://doi.org/10.1158/1538-7445.AM10-169
Published: 15 April 2010
View articletitled, Abstract 169: The origin of colorectal cancer with CpG island methylator phenotype
Journal Articles

Abstract 3476: Combined blockade of IGF-I receptor and VEGF for gastric cancer

Yasushi Adachi, Hiroyuki Yamamoto, Hua Li, Hirokazu Ohashhi, Masanori Ii, Yoshiaki Arimura, Takao Endo, Yasuo Kato, David P. Carbone, Kohzoh Imai, Yasuhisa Shinomura
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3476.
https://doi.org/10.1158/1538-7445.AM10-3476
Published: 15 April 2010
View articletitled, Abstract 3476: Combined blockade of IGF-I receptor and VEGF for gastric cancer
Journal Articles

Epigenetic Inactivation of the Circadian Clock Gene BMAL1 in Hematologic Malignancies

Hiroaki Taniguchi, Agustin F. Fernández, Fernando Setién, Santiago Ropero, Esteban Ballestar, Alberto Villanueva, Hiroyuki Yamamoto, Kohzoh Imai, Yasuhisa Shinomura, Manel Esteller
Journal: Cancer Research
Cancer Res (2009) 69 (21): 8447–8454.
https://doi.org/10.1158/0008-5472.CAN-09-0551
Published: 28 October 2009
View articletitled, Epigenetic Inactivation of the Circadian Clock Gene BMAL1 in Hematologic Malignancies
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Includes: Supplementary data
Journal Articles

Abstract #796: Insulin-like growth factor-I receptor blockade reduces the invasiveness of gastrointestinal cancers via blocking production of matrilysin

Yasushi Adachi, Rong Li, Hiroyuki Yamamoto, Yongfen Min, Yu Wang, Hua Li, Masanori Ii, Choon-Taek Lee, Takao Endo, Kohzoh Imai, David Carbone, Yasuhisa Shinomura
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 796.
Published: 01 May 2009
View articletitled, Abstract #796: Insulin-like growth factor-I receptor blockade reduces the invasiveness of gastrointestinal cancers via blocking production of matrilysin
Journal Articles

Abstract #3442: p53 family members regulate the expression of the apolipoprotein D gene

Yasushi Sasaki, Naoki Anbo, Masashi Idogawa, Hiroaki Mita, Minoru Toyota, Kohzoh Imai, Yasuhisa Shinomura, Takashi Tokino
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3442.
Published: 01 May 2009
View articletitled, Abstract #3442: p53 family members regulate the expression of the apolipoprotein D gene
Journal Articles

Abstract #3797: A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells.

Masashi Idogawa, Yasushi Sasaki, Kohzoh Imai, Yasuhisa Shinomura, Takashi Tokino
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3797.
Published: 01 May 2009
View articletitled, Abstract #3797: A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells.
Journal Articles

Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer

Minoru Toyota, Hiromu Suzuki, Yasushi Sasaki, Reo Maruyama, Kohzoh Imai, Yasuhisa Shinomura, Takashi Tokino
Journal: Cancer Research
Cancer Res (2008) 68 (11): 4123–4132.
https://doi.org/10.1158/0008-5472.CAN-08-0325
Published: 02 June 2008
View articletitled, Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer
Open the PDF for Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer in another window
Includes: Supplementary data