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Klaus Pantel
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Journal Articles

Abstract 1145: Morphological evaluation of chromosomal instability in circulating tumor cells and prediction of taxane resistance in metastatic prostate cancer: a prespecified sub-analysis of the CARD trial

Free
Ossian Longoria, Jan Rekowski, Santosh Gupta, Nick Beije, Klaus Pantel, Eleni Efstathiou, Cora Sternberg, Daniel Castellano, Karim Fizazi, Bertrand Tombal, Adam Sharp, Oliver Sartor, Sandrine Mace, Christine Geffriaud-Ricouard, Richard Wenstrup, Ronald de Wit, Johann de Bono
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1145.
https://doi.org/10.1158/1538-7445.AM2025-1145
Published: 21 April 2025
View articletitled, Abstract 1145: Morphological evaluation of chromosomal instability in circulating tumor cells and prediction of taxane resistance in metastatic prostate cancer: a prespecified sub-analysis of the CARD trial
Journal Articles

Abstract 5741: 6-((1,4-naphthoquinone-2-yl)methyl)thio-glucose conjugates, a novel targeted approach for advanced prostate cancer

Free
Sergey Dyshlovoy, Tobias Busenbender, Dmitry Pelageev, Jessica Hauschild, Moritz Kaune, Lukas Böckelmann, Christoph Krisp, Mohamed Elsesy, Alexandra Zielinski, Thomas Mair, Simone Venz, Malte Kriegs, Konstantin Hoffer, Yuri Sabutski, Ksenia Borisova, Nadja Strewinsky, Svetlana Kovach, Ekaterina Khmelevskaya, Klaus Pantel, Hartmut Schlüter, Victor Anufriev, Derya Tilki, Markus Graefen, Wael Mansour, Carsten Bokemeyer, Gunhild von Amsberg
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5741.
https://doi.org/10.1158/1538-7445.AM2025-5741
Published: 21 April 2025
View articletitled, Abstract 5741: 6-((1,4-naphthoquinone-2-yl)methyl)thio-glucose conjugates, a novel targeted approach for advanced prostate cancer
Journal Articles

Abstract 5876: ctDNA as predictor for systemic therapy response in patients with colorectal cancer: A systematic review and meta-analysis

Free
Anja Holz, Bidisha Paul, Antonia Zapf, Klaus Pantel, Simon A. Joosse
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5876.
https://doi.org/10.1158/1538-7445.AM2025-5876
Published: 21 April 2025
View articletitled, Abstract 5876: ctDNA as predictor for systemic therapy response in patients with colorectal cancer: A systematic review and meta-analysis
Journal Articles

Abstract PS06-06: Analysis of ctDNA for the detection of minimal residual disease (MRD) using a tissue-free, multiomic assay in patients with early-stage breast cancer

Free
Wolfgang Janni, Thomas Friedl, Brigitte Rack, Peter A. Fasching, Andreas Hartkopf, Hans Tesch, Ralf Lorenz, Georg Heinrich, Jens-Uwe Blohmer, Tanja Fehm, Volkmar Müller, Andreas Schneeweiss, Matthias Beckmann, Matthias Ruebner, Nadia Harbeck, Klaus Pantel, Derek Dustin, Mingyang Cai
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS06-06.
https://doi.org/10.1158/1538-7445.SABCS23-PS06-06
Published: 02 May 2024
View articletitled, Abstract PS06-06: Analysis of ctDNA for the detection of minimal residual disease (MRD) using a tissue-free, multiomic assay in patients with early-stage breast cancer
Journal Articles

Abstract PO1-20-05: SURVIVE study – a multicenter, randomized, controlled phase 3 superiority trial, evaluating liquid biopsy guided intensified follow-up surveillance in women with intermediate-to high-risk early breast cancer

Free
Franziska Mergel, Sophia Huesmann, Thomas Friedl, Kerstin Pfister, Tatjana Braun, Angelina Fink, Forca Mehmeti, Tanja Fehm, Volkmar Müller, Klaus Pantel, Andreas Hartkopf, Elisabeth Wiesmüller, Brigitte Rack, Wolfgang Janni
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-20-05.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-20-05
Published: 02 May 2024
View articletitled, Abstract PO1-20-05: SURVIVE study – a multicenter, randomized, controlled phase 3 superiority trial, evaluating liquid biopsy guided intensified follow-up surveillance in women with intermediate-to high-risk early breast cancer
Journal Articles

Abstract PO4-19-01: The SURVIVE-HERoes trial – a secondary adjuvant treatment intervention study with trastuzumab-deruxtecan in patients with HER2 positive/HER2 low early breast cancer and a molecular relapse, based on a positive ctDNA result

Free
Sophia Huesmann, Franziska Mergel, Kerstin Pfister, Angelina Fink, Forca Mehmeti, Peter Möller, Tanja Fehm, Volkmar Müller, Klaus Pantel, Thomas Friedl, Andreas Hartkopf, Brigitte Rack, Wolfgang Janni
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-19-01.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-19-01
Published: 02 May 2024
View articletitled, Abstract PO4-19-01: The SURVIVE-HERoes trial – a secondary adjuvant treatment intervention study with trastuzumab-deruxtecan in patients with HER2 positive/HER2 low early breast cancer and a molecular relapse, based on a positive ctDNA result
Journal Articles

Abstract 2415: Resistance to immune checkpoint inhibitor (ICI) therapy in metastatic melanoma is revealed by deep circulating tumor DNA tracking in concert with tumor immune profiling

Free
Charles W. Abbott, Laura Keller, Isabel Heidrich, Julian Kött, Glenn Geidel, Daniel J. Smit, Ronald Simon, Stefan Schneider, Jason Pugh, Sean M. Boyle, Richard O. Chen, Klaus Pantel, Christoffer Gebhardt
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2415.
https://doi.org/10.1158/1538-7445.AM2024-2415
Published: 22 March 2024
View articletitled, Abstract 2415: Resistance to immune checkpoint inhibitor (ICI) therapy in metastatic melanoma is revealed by deep circulating tumor DNA tracking in concert with tumor immune profiling
Journal Articles

Abstract 3023: Master corepressor inactivation through oncogene suppressor RAI2 mediated polymerization

Free
Nishit Goradia, Stefan Werner, Edukondalu Mullapudi, Gunhild von Amsberg, Klaus Pantel, Matthias Wilmanns
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3023.
https://doi.org/10.1158/1538-7445.AM2024-3023
Published: 22 March 2024
View articletitled, Abstract 3023: Master corepressor inactivation through oncogene suppressor RAI2 mediated polymerization
Journal Articles

Abstract 6558: Ultra-sensitive ctDNA detection predicts response to immune checkpoint inhibition in advanced melanoma patients

Free
Christoffer Gebhardt, Laura Keller, Isabel Heidrich, Julian Koett, Glenn Geidel, Daniel J. Smit, Ronald Simon, Stefan W. Schneider, Jason Pugh, Charles W. Abbott, Sean Boyle, Richard O. Chen, Klaus Pantel
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6558.
https://doi.org/10.1158/1538-7445.AM2024-6558
Published: 22 March 2024
View articletitled, Abstract 6558: Ultra-sensitive ctDNA detection predicts response to immune checkpoint inhibition in advanced melanoma patients
Journal Articles

Abstract 5827: Identification of potential novel drivers and biomarkers of CDK4/6 inhibitor resistance in metastatic breast cancer

Free
Leonie F. Ott, Malik Alawi, Malgorzata Stoupiec, Elena Laakmann, Malte Kriegs, Volkmar Müller, Klaus Pantel, Sabine Riethdorf
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5827.
https://doi.org/10.1158/1538-7445.AM2024-5827
Published: 22 March 2024
View articletitled, Abstract 5827: Identification of potential novel drivers and biomarkers of CDK4/6 inhibitor resistance in metastatic breast cancer
Journal Articles

Abstract 3370: Liquid biopsy approaches to determine tumor cell heterogeneity in advanced prostate cancer

Free
Lina Merkens, Sarah Greimeier, Sabine Riethdorf, Klaus Pantel, Gunhild von Amsberg, Stefan Werner
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3370.
https://doi.org/10.1158/1538-7445.AM2023-3370
Published: 04 April 2023
View articletitled, Abstract 3370: Liquid biopsy approaches to determine tumor cell heterogeneity in advanced prostate cancer
Journal Articles

Abstract 3724: RAI2 controls polycomb-mediated repression of CDKN1A by its interaction with CtBP1

Free
Sarah Greimeier, Bettina Steinbach, Simon Sander, Lina Merkens, Nishit Goradia, Matthias Wilmanns, Eric Metzger, Klaus Pantel, Stefan Werner
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3724.
https://doi.org/10.1158/1538-7445.AM2023-3724
Published: 04 April 2023
View articletitled, Abstract 3724: RAI2 controls polycomb-mediated repression of CDKN1A by its interaction with CtBP1
Journal Articles

Abstract 2298: Ultra-sensitive tumor-informed ctDNA assay predicts survival in advanced melanoma patients treated with immune checkpoint inhibition

Free
Laura Keller, Isabel Heidrich, Julian Kött, Charles W. Abbott, Sean Boyle, Jason Pugh, Richard O. Chen, Glen Geidel, Simon Ronald, Stephan W. Schneider, Christoffer Gebhardt, Klaus Pantel
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2298.
https://doi.org/10.1158/1538-7445.AM2023-2298
Published: 04 April 2023
View articletitled, Abstract 2298: Ultra-sensitive tumor-informed ctDNA assay predicts survival in advanced melanoma patients treated with immune checkpoint inhibition
Journal Articles

Abstract 1295: RAI2 is a novel bone metastasis-associated gene, mediating a vicious cross talk between breast cancer cells and osteoclasts

Free
Thais Pereira Veiga, Stefan Werner, Desiree Loreth, Michael Horn, Melanie Groninger, Moritz Grabe, Anke Baranowsky, Hanna Taipaleenmäki, Laura Brylka, Jolanthe Kropidlowski, Thorsten Schinke, Klaus Pantel, Harriet Wikman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1295.
https://doi.org/10.1158/1538-7445.AM2023-1295
Published: 04 April 2023
View articletitled, Abstract 1295: RAI2 is a novel bone metastasis-associated gene, mediating a vicious cross talk between breast cancer cells and osteoclasts
Journal Articles

Abstract 1189: MERTK is a target in the microenviroenment of osteolytic bone metastasis

Free
Janik Engelmann, Jennifer Zarrer, Kristoffer Riecken, Jonas Waizenegger, Maria Elena Vargas-Delgado, Lara Meier, Carsten Bokemeyer, Klaus Pantel, Emily Alberto, Sourav Ghosh, Carla Rothlin, Eric Hesse, Hanna Taipaleenmäki, Isabel Ben-Batalla, Sonja Loges
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1189.
https://doi.org/10.1158/1538-7445.AM2023-1189
Published: 04 April 2023
View articletitled, Abstract 1189: MERTK is a target in the microenviroenment of osteolytic bone metastasis
Journal Articles

Abstract 1447: Retinoic acid-induced 2 driven polymerization of c-terminal binding proteins sustains epithelial differentiation in castration-resistant prostate cancer

Free
Stefan Werner, Nishit Goradia, Edukondalu Mullapudi, Lina Merkens, Sarah Greimeier, Aleksandra Węglarz, Gunhild von Amsberg, Harriet Wikman, Klaus Pantel, Matthias Wilmanns
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1447.
https://doi.org/10.1158/1538-7445.AM2023-1447
Published: 04 April 2023
View articletitled, Abstract 1447: Retinoic acid-induced 2 driven polymerization of c-terminal binding proteins sustains epithelial differentiation in castration-resistant prostate cancer
Journal Articles

Abstract 6688: Development of a liquid biopsy cfDNA assay for detection of multiple HPV types in cervical neoplasias

Free
Johanna Herbst, Vanessa Vohl, Maroje Krajina, Katharina Prieske, Anna Jaeger, Markus Leffers, Leticia Oliveira-Ferrer, Yvonne Goy, Klaus Pantel, Alexander Sartori, Caren Vollmert, Linn Wölber, Katharina Effenberger, Harriet Wikman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6688.
https://doi.org/10.1158/1538-7445.AM2023-6688
Published: 04 April 2023
View articletitled, Abstract 6688: Development of a liquid biopsy cfDNA assay for detection of multiple HPV types in cervical neoplasias
Journal Articles

Abstract PD18-07: Omission of chemotherapy in the treatment of HER2-positive and hormone-receptor positive metastatic breast cancer – interim results from the randomized phase 3 DETECT V trial

Free
Wolfgang Janni, Tanja Fehm, Volkmar Müller, Fabienne Schochter, Amelie De Gregorio, Thomas Decker, Andreas Hartkopf, Marianne Just, Jacqueline Sagasser, Marcus Schmidt, Pauline Wimberger, Maggie Banys-Paluchowski, Peter A. Fasching, Brigitte Rack, Sabine Riethdorf, Andreas Schneeweiss, Diethelm Wallwiener, Franziska Meier-Stiegen, Natalia Krawczyk, Oliver Hoffmann, Jens-Uwe Blohmer, Dieter Niederacher, Hans Neubauer, Klaus Pantel, Thomas W. Friedl, Jens Huober
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): PD18-07.
https://doi.org/10.1158/1538-7445.SABCS22-PD18-07
Published: 01 March 2023
View articletitled, Abstract PD18-07: Omission of chemotherapy in the treatment of HER2-positive and hormone-receptor positive metastatic breast cancer – interim results from the randomized phase 3 DETECT V trial
Journal Articles

Abstract 3374: Large-scale single-cell whole transcriptomic analyses reveal distinct malignant phenotypes of CTCs from NSCLC patients

Free
Lisa-Marie Rieckmann, Michael Spohn, Ekaterina Selbuz, Claudia Schubert, David Agorku, Lisa Becker, Alina Borchers, Jenny Krause, Lisa Ruff, Sarina Heinemann, Franca Kobus, Jurek Hille, Andia Louisa Tehrany, Janna-Lisa Velthaus-Rusik, Sören Franzenburg, Petros Christopoulos, Hauke Winter, Michael Thomas, Sabine Riethdorf, Nicola Gagliani, Carsten Bokemeyer, Christian F. Krebs, Martin Sprick, Andreas Trumpp, Sven Peine, Olaf Hardt, Nikolas H. Stoecklein, Klaus Pantel, Philipp Rosenstiel, Sonja Loges, Melanie Janning
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3374.
https://doi.org/10.1158/1538-7445.AM2022-3374
Published: 15 June 2022
View articletitled, Abstract 3374: Large-scale single-cell whole transcriptomic analyses reveal distinct malignant phenotypes of CTCs from NSCLC patients
Journal Articles

Abstract 3411: Detection and monitoring of tumor-derived mutations in ctDNA using the UltraSEEK Lung Panel on the MassARRAY System in metastatic NSCLC patients

Free
Paul van der Leest, Melanie Janning, Naomi Rifaela, Maria L. Aguirre Azpurua, Jolanthe Kropidlowski, Sonja Loges, Nicholas Lozano, Alexander Sartori, Darryl Irwin, Pierre-Jean Lamy, T. Jeroen N. Hiltermann, Harry J. Groen, Klaus Pantel, Léon C. van Kempen, Harriet Wikman, Ed Schuuring
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3411.
https://doi.org/10.1158/1538-7445.AM2022-3411
Published: 15 June 2022
View articletitled, Abstract 3411: Detection and monitoring of tumor-derived mutations in ctDNA using the UltraSEEK Lung Panel on the MassARRAY System in metastatic NSCLC patients