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Klas G. Wiman
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Journal Articles

Abstract 4357: Harnessing system xCT- to target mutant p53 cancer cells

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David SH Liu, Matthew Read, Klas G. Wiman, Sue Haupt, Cuong P. Duong, Lars Abrahmsen, Ygal Haupt, Nicholas J. Clemons, Wayne A. Phillips
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4357.
https://doi.org/10.1158/1538-7445.AM2016-4357
Published: 15 July 2016
View articletitled, Abstract 4357: Harnessing system xCT- to target mutant p53 cancer cells
Journal Articles

Abstract 110: The role of the p53 target Wig-1 in senescence and cancer

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Fredrik Jerhammar, Cinzia Bersani, Dijana Djureinovic, Patrick Micke, Klas G. Wiman
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 110.
https://doi.org/10.1158/1538-7445.AM2015-110
Published: 01 August 2015
View articletitled, Abstract 110: The role of the p53 target Wig-1 in senescence and cancer
Journal Articles

Abstract 1639: Strong synergy with APR-246 and DNA-damaging drugs in primary ovarian cancer cells

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Åsa Fransson, Daria Glaessgen, Jessica Alfredsson, Klas G. Wiman, Svetlana Bajalica Lagercrantz, Nina Mohell
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1639.
https://doi.org/10.1158/1538-7445.AM2015-1639
Published: 01 August 2015
View articletitled, Abstract 1639: Strong synergy with APR-246 and DNA-damaging drugs in primary ovarian cancer cells
Journal Articles

Abstract CT204: Preliminary results from PiSARRO, a phase Ib/II study of APR-246, a mutant p53 reactivating small molecule, in combination with standard chemotherapy in platinum-sensitive ovarian cancer

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Mikael von Euler, Klas G. Wiman, Hani Gabra, James D. Brenton, Bristi Basu, Ignace Vergote, Charlie Gourley, Austin Smith, Jessica Alfredsson, Nina Mohell, John A. Green
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT204.
https://doi.org/10.1158/1538-7445.AM2015-CT204
Published: 01 August 2015
View articletitled, Abstract CT204: Preliminary results from PiSARRO, a phase Ib/II study of APR-246, a mutant p53 reactivating small molecule, in combination with standard chemotherapy in platinum-sensitive ovarian cancer
Journal Articles

Abstract 1849: High nuclear expression of the p53 target Wig-1 is associated with poor prognosis in cervical carcinoma

Free
Lidi Xu, Susanne Muller, Mikael Lerner, Svetlana Lagercrantz, Dan Grandér, Keng-Ling Wallin, Klas G. Wiman, Sonia Andersson, Catharina Larsson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1849.
https://doi.org/10.1158/1538-7445.AM2014-1849
Published: 01 October 2014
View articletitled, Abstract 1849: High nuclear expression of the p53 target Wig-1 is associated with poor prognosis in cervical carcinoma
Journal Articles

Abstract 3448: Strong synergistic effects with cisplatin and APR-246, a novel compound reactivating mutant p53, in ovarian cancer cell lines and primary cells from patients.

Free
Nina Mohell, Jessica Alfredsson, Maria Uustalu, Åsa Fransson, Vladimir J.N. Bykov, Klas G. Wiman, Ulf Björklund
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3448.
https://doi.org/10.1158/1538-7445.AM2013-3448
Published: 15 April 2013
View articletitled, Abstract 3448: Strong synergistic effects with cisplatin and APR-246, a novel compound reactivating mutant p53, in ovarian cancer cell lines and primary cells from patients.
Journal Articles

Increased Expression of Insulin-like Growth Factor I Receptor in Malignant Cells Expressing Aberrant p53: Functional Impact

Free
Leonard Girnita, Ada Girnita, Bertha Brodin, Yuntao Xie, Gunnar Nilsson, Anica Dricu, Joakim Lundeberg, Johan Wejde, Armando Bartolazzi, Klas G. Wiman, Olle Larsson
Journal: Cancer Research
Cancer Res (2000) 60 (18): 5278–5283.
Published: 01 September 2000
View articletitled, Increased Expression of Insulin-like Growth Factor I Receptor in Malignant Cells Expressing Aberrant p53: Functional Impact
Open the PDF for Increased Expression of Insulin-like Growth Factor I Receptor in Malignant Cells Expressing Aberrant p53: Functional Impact in another window
Journal Articles

WAF1/CIP1 Is Induced in p53-mediated G1 Arrest and Apoptosis

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Wafik S. El-Deiry, J. Wade Harper, Patrick M. O'Connor, Victor E. Velculescu, Christine E. Canman, Joany Jackman, Jennifer A. Pietenpol, Marilee Burrell, David E. Hill, Yisong Wang, Klas G. Wiman, W. Edward Mercer, Michael B. Kastan, Kurt W. Kohn, Stephen J. Elledge, Kenneth W. Kinzler, Bert Vogelstein
Journal: Cancer Research
Cancer Res (1994) 54 (5): 1169–1174.
Published: 01 March 1994
View articletitled, WAF1/CIP1 Is Induced in p53-mediated G1 Arrest and Apoptosis
Open the PDF for WAF1/CIP1 Is Induced in p53-mediated G1 Arrest and Apoptosis in another window