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Journal Articles

Abstract 2920: Metabolic modulation of the tumor microenvironment using Synthetic Biotic™ Medicines

Kip A. West, Adam Fisher, Dan Leventhal, Anna Sokolovska, Ning Li, Chris Plescia, Mary Castillo, Vincent Isabella, Starsha Kolodziej, Paul Miller, Jose M. Lora

Cancer Res (2018) 78 (13_Supplement): 2920.

https://doi.org/10.1158/1538-7445.AM2018-2920

Published: 01 July 2018

View articletitled, Abstract 2920: Metabolic modulation of the tumor microenvironment using Synthetic Biotic™ Medicines

Journal Articles

Abstract 3433: Deciphering the mechanism of synergy between the Heat Shock Protein 90 inhibitor retaspimycin HCl and docetaxel in preclinical models of non-small cell lung cancer.

Katie O'Callaghan, Brenda C. O'Connell, Bonnie Tillotson, Mark Douglas, Howard Stern, Kip A. West, Janid A. Ali, Paul Changelian, Karen McGovern, Vito J. Palombella, Christian C. Fritz, Jeff L. Kutok

Cancer Res (2013) 73 (8_Supplement): 3433.

https://doi.org/10.1158/1538-7445.AM2013-3433

Published: 15 April 2013

View articletitled, Abstract 3433: Deciphering the mechanism of synergy between the Heat Shock Protein 90 inhibitor retaspimycin HCl and docetaxel in preclinical models of non-small cell lung cancer.

Journal Articles

Abstract 2827: Activity of the proprietary Hsp90 inhibitor IPI-493 in models of colorectal cancer correlates with RAS pathway activation

Kip A. West, Nafeeza Hafeez, John Mac Dougall, Emmanuel Normant, Vito Palombella, Christian Fritz

Cancer Res (2011) 71 (8_Supplement): 2827.

https://doi.org/10.1158/1538-7445.AM2011-2827

Published: 15 April 2011

View articletitled, Abstract 2827: Activity of the proprietary Hsp90 inhibitor IPI-493 in models of colorectal cancer correlates with RAS pathway activation

Journal Articles

Inhibition of the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway but not the MEK/ERK Pathway Attenuates Laminin-Mediated Small Cell Lung Cancer Cellular Survival and Resistance to Imatinib Mesylate or Chemotherapy

Junji Tsurutani, Kip A. West, Jacqueline Sayyah, Joell J. Gills, Phillip A. Dennis

Cancer Res (2005) 65 (18): 8423–8432.

https://doi.org/10.1158/0008-5472.CAN-05-0058

Published: 15 September 2005

View articletitled, Inhibition of the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway but not the MEK/ERK Pathway Attenuates Laminin-Mediated Small Cell Lung Cancer Cellular Survival and Resistance to Imatinib Mesylate or Chemotherapy

Journal Articles

Preferential Inhibition of Akt and Killing of Akt-Dependent Cancer Cells by Rationally Designed Phosphatidylinositol Ether Lipid Analogues

S. Sianna Castillo, John Brognard, Pavel A. Petukhov, Chunyu Zhang, Junji Tsurutani, Courtney A. Granville, Min Li, Michael Jung, Kip A. West, Joell G. Gills, Alan P. Kozikowski, Phillip A. Dennis

Cancer Res (2004) 64 (8): 2782–2792.

https://doi.org/10.1158/0008-5472.CAN-03-1530

Published: 15 April 2004

View articletitled, Preferential Inhibition of Akt and Killing of Akt-Dependent Cancer Cells by Rationally Designed Phosphatidylinositol Ether Lipid Analogues

Journal Articles

Inhibition of EGFR abrogates increased activation of the PI3K/Akt pathway and increased survival of tobacco-carcinogen transformed bronchial epithelial cells.

Courtney A. Granville, Kip A. West, Phillip A. Dennis

Cancer Res (2004) 64 (7_Supplement): 580.

Published: 01 April 2004

View articletitled, Inhibition of EGFR abrogates increased activation of the PI3K/Akt pathway and increased survival of tobacco-carcinogen transformed bronchial epithelial cells.

Journal Articles

Inhibition of the PI3K/Akt/mTOR pathway abrogates laminin-mediated SCLC survival and resistance to Gleevec

Junji Tsurutani, Kip A. West, Jacqueline Sayyah, Phillip A. Dennis

Cancer Res (2004) 64 (7_Supplement): 335–336.

Published: 01 April 2004

View articletitled, Inhibition of the PI3K/Akt/mTOR pathway abrogates laminin-mediated SCLC survival and resistance to Gleevec

Journal Articles

Nicotine increases proliferation of premalignant human bronchial epithelial cells through activation of the EGFR/Akt/mTOR pathway and increased cyclin D1 expression

Joell J. Gills, Kip A. West, John Brognard, Phillip A. Dennis

Cancer Res (2004) 64 (7_Supplement): 941.

Published: 01 April 2004

View articletitled, Nicotine increases proliferation of premalignant human bronchial epithelial cells through activation of the EGFR/Akt/mTOR pathway and increased cyclin D1 expression

Journal Articles

Tobacco Carcinogen-Induced Cellular Transformation Increases Activation of the Phosphatidylinositol 3′-Kinase/Akt Pathway in Vitro and in Vivo

Kip A. West, Ilona R. Linnoila, Steven A. Belinsky, Curtis C. Harris, Phillip A. Dennis

Cancer Res (2004) 64 (2): 446–451.

https://doi.org/10.1158/0008-5472.CAN-03-3241

Published: 26 January 2004

View articletitled, Tobacco Carcinogen-Induced Cellular Transformation Increases Activation of the Phosphatidylinositol 3′-Kinase/Akt Pathway in Vitro and in Vivo

Journal Articles

Altered Protein Kinase C (PKC) Isoforms in Non-Small Cell Lung Cancer Cells: PKCδ Promotes Cellular Survival and Chemotherapeutic Resistance

Amy S. Clark, Kip A. West, Peter M. Blumberg, Phillip A. Dennis

Cancer Res (2003) 63 (4): 780–786.

Published: 15 February 2003

View articletitled, Altered Protein Kinase C (PKC) Isoforms in Non-Small Cell Lung Cancer Cells: PKCδ Promotes Cellular Survival and Chemotherapeutic Resistance

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Abstract 2920: Metabolic modulation of the tumor microenvironment using Synthetic Biotic™ Medicines

Abstract 3433: Deciphering the mechanism of synergy between the Heat Shock Protein 90 inhibitor retaspimycin HCl and docetaxel in preclinical models of non-small cell lung cancer.

Abstract 2827: Activity of the proprietary Hsp90 inhibitor IPI-493 in models of colorectal cancer correlates with RAS pathway activation

Inhibition of the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway but not the MEK/ERK Pathway Attenuates Laminin-Mediated Small Cell Lung Cancer Cellular Survival and Resistance to Imatinib Mesylate or Chemotherapy

Preferential Inhibition of Akt and Killing of Akt-Dependent Cancer Cells by Rationally Designed Phosphatidylinositol Ether Lipid Analogues

Inhibition of EGFR abrogates increased activation of the PI3K/Akt pathway and increased survival of tobacco-carcinogen transformed bronchial epithelial cells.

Inhibition of the PI3K/Akt/mTOR pathway abrogates laminin-mediated SCLC survival and resistance to Gleevec

Nicotine increases proliferation of premalignant human bronchial epithelial cells through activation of the EGFR/Akt/mTOR pathway and increased cyclin D1 expression

Tobacco Carcinogen-Induced Cellular Transformation Increases Activation of the Phosphatidylinositol 3′-Kinase/Akt Pathway in Vitro and in Vivo

Altered Protein Kinase C (PKC) Isoforms in Non-Small Cell Lung Cancer Cells: PKCδ Promotes Cellular Survival and Chemotherapeutic Resistance

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