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Kimitoshi Kohno
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Journal Articles

Abstract LB-183: Y-box binding protein-1 YB-1 negatively regulates ERα expression accompanying by enhanced HER2/ErbB2 expression in breast cancer

Tomohiro Shibata, Hiroto Izumi, Akihiko Kawahara, Satoshi Hattori, Chihiro Fukumitsu, Ryuji Takahashi, Kosuke Watari, Yuichi Murakami, Kimitoshi Kohno, Ken-ichi Ito, Masayoshi Kage, Michihiko Kuwano, Mayumi Ono
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-183.
https://doi.org/10.1158/1538-7445.AM2014-LB-183
Published: 01 October 2014
View articletitled, Abstract LB-183: Y-box binding protein-1 YB-1 negatively regulates ERα expression accompanying by enhanced HER2/ErbB2 expression in breast cancer
Journal Articles

Cisplatin Resistance Associated with PARP Hyperactivation

Judith Michels, Ilio Vitale, Lorenzo Galluzzi, Julien Adam, Ken André Olaussen, Oliver Kepp, Laura Senovilla, Ibtissam Talhaoui, Justine Guegan, David Pierre Enot, Monique Talbot, Angélique Robin, Philippe Girard, Cédric Oréar, Delphine Lissa, Abdul Qader Sukkurwala, Pauline Garcia, Parviz Behnam-Motlagh, Kimitoshi Kohno, Gen Sheng Wu, Catherine Brenner, Philippe Dessen, Murat Saparbaev, Jean-Charles Soria, Maria Castedo, Guido Kroemer
Journal: Cancer Research
Cancer Res (2013) 73 (7): 2271–2280.
https://doi.org/10.1158/0008-5472.CAN-12-3000
Published: 02 April 2013
View articletitled, Cisplatin Resistance Associated with PARP Hyperactivation
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Includes: Supplementary data
Journal Articles

Loss of PTEN Expression by Blocking Nuclear Translocation of EGR1 in Gefitinib-Resistant Lung Cancer Cells Harboring Epidermal Growth Factor Receptor–Activating Mutations

Chizuko Yamamoto, Yuji Basaki, Akihiko Kawahara, Kazutaka Nakashima, Masayoshi Kage, Hiroto Izumi, Kimitoshi Kohno, Hidetaka Uramoto, Kosei Yasumoto, Michihiko Kuwano, Mayumi Ono
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8715–8725.
https://doi.org/10.1158/0008-5472.CAN-10-0043
Published: 31 October 2010
View articletitled, Loss of PTEN Expression by Blocking Nuclear Translocation of EGR1 in Gefitinib-Resistant Lung Cancer Cells Harboring Epidermal Growth Factor Receptor–Activating Mutations
Open the PDF for Loss of PTEN Expression by Blocking Nuclear Translocation of EGR1 in Gefitinib-Resistant Lung Cancer Cells Harboring Epidermal Growth Factor Receptor–Activating Mutations in another window
Includes: Supplementary data
Journal Articles

N-myc Downstream Regulated Gene 1/Cap43 Suppresses Tumor Growth and Angiogenesis of Pancreatic Cancer through Attenuation of Inhibitor of κB Kinase β Expression

Fumihito Hosoi, Hiroto Izumi, Akihiko Kawahara, Yuichi Murakami, Hisafumi Kinoshita, Masayoshi Kage, Kazuto Nishio, Kimitoshi Kohno, Michihiko Kuwano, Mayumi Ono
Journal: Cancer Research
Cancer Res (2009) 69 (12): 4983–4991.
https://doi.org/10.1158/0008-5472.CAN-08-4882
Published: 15 June 2009
View articletitled, N-myc Downstream Regulated Gene 1/Cap43 Suppresses Tumor Growth and Angiogenesis of Pancreatic Cancer through Attenuation of Inhibitor of κB Kinase β Expression
Open the PDF for N-myc Downstream Regulated Gene 1/Cap43 Suppresses Tumor Growth and Angiogenesis of Pancreatic Cancer through Attenuation of Inhibitor of κB Kinase β Expression in another window
Includes: Supplementary data
Journal Articles

Abstract #3174: N-myc downstream regulated gene 1 (NDRG1)/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of NF-\#954;B signaling

Mayumi Ono, Fumihito Hosoi, Hiroto Izumi, Kazuto Nishio, Kimitoshi Kohno, Michihiko Kuwano
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3174.
Published: 01 May 2009
View articletitled, Abstract #3174: N-myc downstream regulated gene 1 (NDRG1)/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of NF-\#954;B signaling
Journal Articles

Programmed Cell Death Protein 4 Down-regulates Y-Box Binding Protein-1 Expression via a Direct Interaction with Twist1 to Suppress Cancer Cell Growth

Masaki Shiota, Hiroto Izumi, Akihide Tanimoto, Mayu Takahashi, Naoya Miyamoto, Eiji Kashiwagi, Akihiko Kidani, Gen Hirano, Daisuke Masubuchi, Yasushi Fukunaka, Yoshihiro Yasuniwa, Seiji Naito, Shigeru Nishizawa, Yasuyuki Sasaguri, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (2009) 69 (7): 3148–3156.
https://doi.org/10.1158/0008-5472.CAN-08-2334
Published: 01 April 2009
View articletitled, Programmed Cell Death Protein 4 Down-regulates Y-Box Binding Protein-1 Expression via a Direct Interaction with Twist1 to Suppress Cancer Cell Growth
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Journal Articles

Expression of HER2 and Estrogen Receptor α Depends upon Nuclear Localization of Y-Box Binding Protein-1 in Human Breast Cancers

Teruhiko Fujii, Akihiko Kawahara, Yuji Basaki, Satoshi Hattori, Kazutaka Nakashima, Kenji Nakano, Kazuo Shirouzu, Kimitoshi Kohno, Takashi Yanagawa, Hideaki Yamana, Kazuto Nishio, Mayumi Ono, Michihiko Kuwano, Masayoshi Kage
Journal: Cancer Research
Cancer Res (2008) 68 (5): 1504–1512.
https://doi.org/10.1158/0008-5472.CAN-07-2362
Published: 03 March 2008
View articletitled, Expression of HER2 and Estrogen Receptor α Depends upon Nuclear Localization of Y-Box Binding Protein-1 in Human Breast Cancers
Open the PDF for Expression of HER2 and Estrogen Receptor α Depends upon Nuclear Localization of Y-Box Binding Protein-1 in Human Breast Cancers in another window
Includes: Supplementary data
Journal Articles

Twist Promotes Tumor Cell Growth through YB-1 Expression

Masaki Shiota, Hiroto Izumi, Takamitsu Onitsuka, Naoya Miyamoto, Eiji Kashiwagi, Akihiko Kidani, Akira Yokomizo, Seiji Naito, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (2008) 68 (1): 98–105.
https://doi.org/10.1158/0008-5472.CAN-07-2981
Published: 02 January 2008
View articletitled, Twist Promotes Tumor Cell Growth through YB-1 Expression
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Journal Articles

The expression of polypeptide GalNAc N-acetylgalactosaminyl transferase-3 in thyroid carcinoma

Yasuhiro Mochizuki, Ken-Ichi Ito, Kazuma Maeno, Minoru Fujimori, Hiroto Izumi, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 436.
Published: 15 April 2006
View articletitled, The expression of polypeptide GalNAc N-acetylgalactosaminyl transferase-3 in thyroid carcinoma
Journal Articles

DNA topoisomerase II poison TAS-103 transactivates GC-box-dependent transcription via acetylation of Sp1

Takeshi Yoshida, Hiroto Izumi, Takayuki Torigoe, Tetsuro Wakasugi, Ichiro Niina, Tomonori Igarashi, Takuya Imaizumi, Yasutomo Momii, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1174.
Published: 01 May 2005
View articletitled, DNA topoisomerase II poison TAS-103 transactivates GC-box-dependent transcription via acetylation of Sp1
Journal Articles

Increased nuclear localization of transcription factor YB-1 accompanied by upregulation of P-glycoprotein in breast cancer pretreated with paclitaxel

Tomoyuki Fujita, Ken-Ichi Ito, Hiroto Izumi, Kazuma Maeno, Yoshihisa Hama, Kiyoshi Shingu, Morihiko Kimura, Muneaki Sano, Hiroshi Nakagomi, Shin-Ichi Tsuchiya, Minoru Fujimori, Kimitoshi Kohno, Jun Amano
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 124.
Published: 01 May 2005
View articletitled, Increased nuclear localization of transcription factor YB-1 accompanied by upregulation of P-glycoprotein in breast cancer pretreated with paclitaxel
Journal Articles

ZNF143 activates gene expression in response to DNA damage, and binds to cisplatin-modified DNA

Tetsuro Wakasugi, Hiroto Izumi, Takeshi Yoshida, Tomonori Igarashi, Ichiro Niina, Takuya Imaizumi, Yasutomo Momii, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 349.
Published: 01 May 2005
View articletitled, ZNF143 activates gene expression in response to DNA damage, and binds to cisplatin-modified DNA
Journal Articles

Activating Transcription Factor 4 Increases the Cisplatin Resistance of Human Cancer Cell Lines

Mizuho Tanabe, Hiroto Izumi, Tomoko Ise, Shun Higuchi, Takao Yamori, Kosei Yasumoto, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (2003) 63 (24): 8592–8595.
Published: 24 December 2003
View articletitled, Activating Transcription Factor 4 Increases the Cisplatin Resistance of Human Cancer Cell Lines
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Journal Articles

p53 Physically Interacts with Mitochondrial Transcription Factor A and Differentially Regulates Binding to Damaged DNA

Yoichiro Yoshida, Hiroto Izumi, Takayuki Torigoe, Hiroshi Ishiguchi, Hideaki Itoh, Dongchon Kang, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (2003) 63 (13): 3729–3734.
Published: 01 July 2003
View articletitled, p53 Physically Interacts with Mitochondrial Transcription Factor A and Differentially Regulates Binding to Damaged DNA
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Journal Articles

Transcriptional Activation of the Human HMG1 Gene in Cisplatin-resistant Human Cancer Cells

Gunji Nagatani, Minoru Nomoto, Hiroshi Takano, Tomoko Ise, Ken Kato, Toshihiro Imamura, Hiroto Izumi, Kazumi Makishima, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (2001) 61 (4): 1592–1597.
Published: 02 February 2001
View articletitled, Transcriptional Activation of the Human HMG1 Gene in Cisplatin-resistant Human Cancer Cells
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Journal Articles

Interferon γ-dependent Induction of Thymidine Phosphorylase/Platelet-derived Endothelial Growth Factor through γ-Activated Sequence-like Element in Human Macrophages

Hisatsugu Goto, Kimitoshi Kohno, Saburo Sone, Shin-ichi Akiyama, Michihiko Kuwano, Mayumi Ono
Journal: Cancer Research
Cancer Res (2001) 61 (2): 469–473.
Published: 01 January 2001
View articletitled, Interferon γ-dependent Induction of Thymidine Phosphorylase/Platelet-derived Endothelial Growth Factor through γ-Activated Sequence-like Element in Human Macrophages
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Journal Articles

Structural Basis for the Regulation of UDP-N-Acetyl-α-d-galactosamine: Polypeptide N-Acetylgalactosaminyl Transferase-3 Gene Expression in Adenocarcinoma Cells1

Minoru Nomoto, Hiroto Izumi, Tomoko Ise, Ken Kato, Hiroshi Takano, Gunji Nagatani, Kazunori Shibao, Ryo Ohta, Toshihiro Imamura, Michihiko Kuwano, Ken-ichi Matsuo, Yuji Yamada, Hideaki Itoh, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (1999) 59 (24): 6214–6222.
Published: 15 December 1999
View articletitled, Structural Basis for the Regulation of UDP-N-Acetyl-α-d-galactosamine: Polypeptide N-Acetylgalactosaminyl Transferase-3 Gene Expression in Adenocarcinoma Cells1
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Journal Articles

Transcription Factor Y-Box Binding Protein 1 Binds Preferentially to Cisplatin-modified DNA and Interacts with Proliferating Cell Nuclear Antigen

Tomoko Ise, Gunji Nagatani, Toshihiro Imamura, Ken Kato, Hiroshi Takano, Minoru Nomoto, Hiroto Izumi, Haruki Ohmori, Tatsuro Okamoto, Takefumi Ohga, Takeshi Uchiumi, Michihiko Kuwano, Kimitoshi Kohno
Journal: Cancer Research
Cancer Res (1999) 59 (2): 342–346.
Published: 15 January 1999
View articletitled, Transcription Factor Y-Box Binding Protein 1 Binds Preferentially to Cisplatin-modified DNA and Interacts with Proliferating Cell Nuclear Antigen
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Journal Articles

Enhanced Coexpression of Thioredoxin and High Mobility Group Protein 1 Genes in Human Hepatocellular Carcinoma and the Possible Association with Decreased Sensitivity to Cisplatin

Naoyuki Kawahara, Toshiya Tanaka, Akira Yokomizo, Hiroki Nanri, Mayumi Ono, Morimasa Wada, Kimitoshi Kohno, Kenji Takenaka, Keizo Sugimachi, Michihiko Kuwano
Journal: Cancer Research
Cancer Res (1996) 56 (23): 5330–5333.
Published: 01 December 1996
View articletitled, Enhanced Coexpression of Thioredoxin and High Mobility Group Protein 1 Genes in Human Hepatocellular Carcinoma and the Possible Association with Decreased Sensitivity to Cisplatin
Open the PDF for Enhanced Coexpression of Thioredoxin and High Mobility Group Protein 1 Genes in Human Hepatocellular Carcinoma and the Possible Association with Decreased Sensitivity to Cisplatin in another window
Journal Articles

A Human Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene Is Overexpressed in Cisplatin-resistant Human Cancer Cell Lines with Decreased Drug Accumulation

Ken Taniguchi, Morimasa Wada, Kimitoshi Kohno, Takanori Nakamura, Takeshi Kawabe, Mina Kawakami, Kazuhiro Kagotani, Katsuzumi Okumura, Shin-ichi Akiyama, Michihiko Kuwano
Journal: Cancer Research
Cancer Res (1996) 56 (18): 4124–4129.
Published: 01 September 1996
View articletitled, A Human Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene Is Overexpressed in Cisplatin-resistant Human Cancer Cell Lines with Decreased Drug Accumulation
Open the PDF for A Human Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene Is Overexpressed in Cisplatin-resistant Human Cancer Cell Lines with Decreased Drug Accumulation in another window