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Keun Seok Lee
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Journal Articles

Abstract 6038: Target therapeutics evaluation using patient-derived organoids from breast cancer

Hyunjin Kim, So-Youn Jung, Sung Hoon Sim, Hee Jung Chae, Yun-Hee Kim, Yena Kim, Eun Gyeoung Lee, Seeyoun Lee, Jai Hong Han, Young Mi Kwon, Eun Sook Lee, Keun Seok Lee, Sun-Young Kong
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6038.
DOI: https://doi.org/10.1158/1538-7445.AM2022-6038
Published: 15 June 2022
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Abstract PD10-04: Phase Ib/II open-label, randomized trial of atezolizumab (atezo) with ipatasertib (ipat) and fulvestrant (fulv) vs control in MORPHEUS-HR+ breast cancer (M-HR+ BC) and atezo with ipat vs control in MORPHEUS triple negative breast cancer (M-TNBC)

Sara A. Hurvitz, Valentina Boni, Elizabeth Comen, Seock-Ah Im, Kyung Hae Jung, Sung-Bae Kim, Keun Seok Lee, Sherene Loi, Hope S. Rugo, Amir Sonnenblick, Melinda L. Telli, Kelly DuPree, Marcella Fasso, Ya-Chen Lin, Mina Nikanjam, Frauke Schimmoller, Xiaosong Zhang, Jing Zhu, Peter Schmid
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD10-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-PD10-04
Published: 15 February 2022
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Journal Articles

Abstract P1-08-23: Androgen receptor as predictive marker for pathologic complete response in breast cancer with neoadjuvant chemotherapy

Eun-Gyeong Lee, Dong-Eun Lee, Jai Hong Han, Seeyoun Lee, Han-Sung Kang, Eun Sook Lee, Youngmee Kwon, Hyun Hee Kim, Hee Jung Chae, Sung Hoon Sim, Keun Seok Lee, So-Youn Jung
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-08-23.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P1-08-23
Published: 15 February 2022
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Abstract P1-18-32: A nationwide real-world study for evaluation of efficacy and safety of T-DM1 in patients with HER2-positive locally-advanced unresectable or metastatic breast cancer in Korea (KCSG BR19-15)

Sun Kyung Baek, Jae-Ho Jeong, Yeon-Hee Park, Hee Kyung Ahn, Min Hwan Kim, In Hae Park, Young Ju Suh, Dae-Won Lee, Sung Hoon Sim, Jee Hyun Kim, Hyun-Jeong Shim, Yeesoo Chae, Su-Jin Koh, Hyorak Lee, Jieun Lee, Jae-Ho Byun, Youngmi Seol, Eun Mi Lee, Jin Seok Ahn, Kyung-Hae Jung, Seock-Ah Im, Keun Seok Lee, Joohyuk Sohn, Kyoung Eun Lee
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-18-32.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P1-18-32
Published: 15 February 2022
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Journal Articles

Abstract P1-16-01: Pemetrexed plus vinorelbine versus vinorelbine monotherapy in patients with metastatic breast cancer: A randomized, open-label, multicenter, phase II trial (KCSG-BR15-17)

Dae-Won Lee, Yeon Hee Park, Kyung-Hae Jung, Kyung-Hun Lee, Keun Seok Lee, Joohyuk Sohn, Hee Kyung Ahn, Jae Ho Jeong, Su-Jin Koh, Jee Hyun Kim, Han Jo Kim, Kyoung Eun Lee, Hee-Jun Kim, Ki Hyeong Lee, Kyong Hwa Park, Jieun Lee, Hye Sung Won, Tae-Yong Kim, Seock-Ah Im
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-16-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P1-16-01
Published: 15 February 2022
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Journal Articles

Abstract CT234: VASTUS - a phase 1b/2a basket trial of a new PARP inhibitor, IDX-1197, including PARP inhibitor resistant cohort

Kyung-Hun Lee, Ahrum Min, Hee Kyung Ahn, Keun Seok Lee, Yong Wha Moon, Seung Tae Kim, Jeong Eun Kim, Joo Hyuk Sohn, Il Hwan Kim, Woo Kyun Bae, Myong Jae Lee, Eun-Jihn Roh, Chan-Young Ock, Won Sik Lee, Seock-Ah Im
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT234.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT234
Published: 01 July 2021
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Abstract PD2-04: Updated overall survival (OS) results from the phase III MONALEESA-7 trial of pre- or perimenopausal patients with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2−) advanced breast cancer (ABC) treated with endocrine therapy (ET) ± ribociclib

Debu Tripathy, Seock-Ah Im, Marco Colleoni, Fabio Franke, Aditya Bardia, Nadia Harbeck, Sara Hurvitz, Louis Chow, Joohyuk Sohn, Keun Seok Lee, Saul Campos-Gomez, Rafael Villanueva Vazquez, Kyung Hae Jung, K Govind Babu, Paul Wheatley-Price, Michelino De Laurentiis, Young-Hyuck Im, Sherko Kümmel, Nagi El-Saghir, Mei-Ching Liu, Sharonjeet Kaur, Claudia Gasch, Craig Wang, Yongyu Wang, Arunava Chakravartty, Yen-Shen Lu
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD2-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PD2-04
Published: 15 February 2021
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Journal Articles

Abstract PD14-04: Contribution of tumor and immune cells to PD-L1 as a predictive biomarker in triple-negative breast cancer (TNBC): Analysis from KEYNOTE-119

Eric P. Winer, Oleg Lipatov, Seock-Ah Im, Anthony Goncalves, Eva Muñoz-Couselo, Keun Seok Lee, Zbigniew Nowecki, Peter Schmid, Kenji Tamura, Laura Testa, Isabell Witzel, Shoichiro Ohtani, Stephanie Hund, Karina Kulangara, Vassiliki Karantza, Jaime A. Mejia, Junshui Ma, Petar Jelinic, Lingkang Huang, Kenneth Emancipator, Javier Cortes
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD14-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PD14-04
Published: 15 February 2021
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Abstract PD3-06: Updated results from DESTINY-breast01, a phase 2 trial of trastuzumab deruxtecan (T-DXd ) in HER2 positive metastatic breast cancer

Shanu Modi, Cristina Saura, Toshinari Yamashita, Yeon Hee Park, Sung-Bae Kim, Kenji Tamura, Fabrice Andre, Hiroji Iwata, Yoshinori Ito, Junji Tsurutani, Joohyuk Sohn, Neelima Denduluri, Christophe Perrin, Kenjiro Aogi, Eriko Tokunaga, Seock-Ah Im, Keun Seok Lee, Sara A Hurvitz, Javier Cortes, Caleb Lee, Yali Liu, Lin Zhang, Javad Shahidi, Antoine Yver, Jose Baselga, Ian E Krop
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD3-06.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PD3-06
Published: 15 February 2021
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Abstract PS12-01: Pembrolizumab versus chemotherapy for previously treated metastatic triple-negative breast cancer (KEYNOTE-119): Efficacy in patients with lung or liver metastases

Eric Winer, Oleg Lipatov, Seock-Ah Im, Anthony Goncalves, Keun Seok Lee, Peter Schmid, Laura Testa, Isabell Witzel, Shoichiro Ohtani, NIcholas Turner, Stefania Zambelli, Nadia Harbeck, Fabrice Andre, Rebecca Dent, Jianxin Lin, Vassiliki Karantza, Jaime Mejia, Javier Cortes
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS12-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS12-01
Published: 15 February 2021
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Journal Articles

Abstract 1667: Comparison of drug responses using patient-derived xenograft (PDX) and patient-derived organoid (PDO) models from treatment-refractory breast cancer

Jin-Sun Ryu, You-sun Noh, Bo-Ra Kim, Yun-Hee Kim, A-Ra Jeon, Sung Hoon Sim, In Hae Park, Eun Gyeong Lee, Eun Sook Lee, Keun Seok Lee, Sun-Young Kong
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1667.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1667
Published: 15 August 2020
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Journal Articles

Abstract GS1-03: [Fam-] trastuzumab deruxtecan (T-DXd; DS-8201a) in subjects with HER2-positive metastatic breast cancer previously treated with T-DM1: A phase 2, multicenter, open-label study (DESTINY-Breast01)

Ian E Krop, Cristina Saura, Toshinari Yamashita, Yeon Hee Park, Sung-Bae Kim, Kenji Tamura, Fabrice André, Hiroji Iwata, Yoshinori Ito, Junji Tsurutani, Joohyuk Sohn, Neelima Denduluri, Christophe Perrin, Kenjiro Aogi, Eriko Tokunaga, Seock-Ah Im, Keun Seok Lee, Sara Hurvitz, Javier Cortes, Caleb Lee, Shuquan Chen, Lin Zhang, Javad Shahidi, Antoine Yver, Shanu Modi
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): GS1-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-GS1-03
Published: 15 February 2020
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Journal Articles

Abstract P3-08-50: Genome-wide association study predict prognosis of hormone receptor positive metastatic breast cancer in premenopausal women with endocrine therapy

Ji-Yeon Kim, Seock-Ah Im, Kyung Hae Jung, Keun Seok Lee, Joohyuk Sohn, Jee Hyun Kim, Hae Hyun Jung, Minjoo Lee, Young-Hyuck Im
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-08-50.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P3-08-50
Published: 15 February 2020
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Abstract CT141: Genetic landscape of premenopausal HR+/HER2- advanced breast cancer (ABC) based on comprehensive circulating tumor DNA analysis and association with clinical outcomes in the Phase III MONALEESA-7 trial

Aditya Bardia, Faye Su, Nadia Solovieff, Seock-Ah Im, Joohyuk Sohn, Keun Seok Lee, Saul Campos-Gomez, Kyung Hae Jung, Rafael Villanueva Vazquez, Yen-Shen Lu, Fabio Franke, Sara Hurvitz, Nadia Harbeck, Louis Chow, Karen Rodriguez Lorenc, Tetiana Taran, Naveen Babbar, Debu Tripathy
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT141.
DOI: https://doi.org/10.1158/1538-7445.AM2019-CT141
Published: 01 July 2019
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Abstract 3424: Consensus molecular subtype of triple negative breast cancer to implicate in chemotherapy response

Jihyun Kim, Doyeong Yu, Jiyoon Noh, Wooyeong Jang, Hanna Yang, Youngmee Kwon, Keun Seok Lee, Sung Hoon Sim, Sun-Young Kong, In Hae Park, Charny Park
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3424.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3424
Published: 01 July 2019
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Abstract 4279: The genomic profile investigation of metastatic triple-negative breast cancer for precision medicine achievement

Wooyeong Jang, Jihyun Kim, Hanna Yang, Youngmee Kwon, Keun Seok Lee, Sung Hoon Sim, Sun-Young Kong, Kyounghee An, In Hae Park, Charny Park
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4279.
DOI: https://doi.org/10.1158/1538-7445.AM2018-4279
Published: 01 July 2018
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Journal Articles

Abstract 5537: Circulating tumor DNA analysis for ESR1 mutations in patients with hormone receptor-positive metastatic breast cancer

Sung Hoon Sim, Su Yeon Jeon, Kyoung Hee An, Sun Young Kong, Min Jung Kwon, Keun Seok Lee, In Hae Park
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5537.
DOI: https://doi.org/10.1158/1538-7445.AM2018-5537
Published: 01 July 2018
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Abstract 3474: Prevalence of BRCA1 and BRCA2 small mutation and large genomic rearrangements in breast cancer patients visiting a genetic counseling clinic

Ji Yeon Sohn, Boyoung Park, Kyong-Ah Yoon, Soo Jin Park, Moo Hyun Lee, Eun Hae Cho, Keun Seok Lee, Myong Cheol Lim, Sun-Young Kong, Eun Sook Lee
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3474.
DOI: https://doi.org/10.1158/1538-7445.AM2016-3474
Published: 15 July 2016
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Abstract P3-10-04: A open-label, randomized, parallel, phase III trial to evaluate the efficacy and safety of Genexol®-PM compared to Genexol®(conventional paclitaxel with cremorphor EL) in recurrent or metastatic breast cancer patients

Jung Sil Ro, Joo Hyuk Sohn, Sung Bae Kim, Keun Seok Lee, Joo Seop Chung, Jae Hoo Park, Soo Hyeon Lee, Tae You Kim, Kyung Hae Jung, Eun Kyung Cho, Yang Soo Kim, Hong Suk Song, Jae Hong Seo, Hun Mo Ryoo, Sun Ah Lee, So Young Yoon, Chul Soo Kim, Yong Tai Kim, Hwa Jung Sung, Si Young Kim, Yong Jin Lee
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P3-10-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS14-P3-10-04
Published: 01 May 2015
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Abstract P5-04-14: Decreased functions of natural killer cells in peripheral blood of advanced triple negative breast cancer patients

In Hae Park, Sun-Young Kong, Joo Hyun Kang, Hye Jin Mo, Tae Sik Kim, Keun Seok Lee, Jungsil Ro
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P5-04-14.
DOI: https://doi.org/10.1158/1538-7445.SABCS14-P5-04-14
Published: 01 May 2015
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