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Abstract PO-106: Genomic heterogeneity and clonal dynamics of resistance evolution and metastatic progression in rectal cancer

Daniela Hirsch, Judith Lieberich, Kerstin Heselmeyer-Haddad, Yonca Ceribas, Michael Kelly, Keyur Talsania, Yongmei Zhao, Timo Gaiser, Thomas Ried

Cancer Res (2020) 80 (21_Supplement): PO-106.

DOI: https://doi.org/10.1158/1538-7445.TUMHET2020-PO-106

Published: 03 November 2020

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Journal Articles

Abstract 2498: miFISH single cell analysis as a potential tool to stratify the progression risk in patients with Atypical Ductal Hyperplasia (ADH)

Kiara Whitaker, Jausheng Tzeng, Daniela Hirsch, Irianna Torres, Steven Brower, Gert Auer, Miguel Sanchez, Thomas Ried, Kerstin Heselmeyer-Haddad

Cancer Res (2020) 80 (16_Supplement): 2498.

DOI: https://doi.org/10.1158/1538-7445.AM2020-2498

Published: 15 August 2020

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Journal Articles

Abstract 2189: Genomic dynamics in breast cancer progression analyzed by miFISH analysis

Irianna Marie Torres, Leanora Hernandez, Jausheng Tzeng, Russell Schwartz, Alejandro Schaffer, Edward Michael Gertz, Daniela Hirsch, Steven Brower, Miguel Sanchez, Gert Auer, Kerstin Heselmeyer-Haddad, Thomas Ried

Cancer Res (2018) 78 (13_Supplement): 2189.

DOI: https://doi.org/10.1158/1538-7445.AM2018-2189

Published: 01 July 2018

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Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis

Daniela D. Hirsch, Darawalee Wangsa, Yue Hu, Jack Zhu, David Petersen, Daniel C. Edelman, Paul S. Meltzer, Bao Tran, Kerstin Heselmeyer-Haddad, Thomas Ried, Timo Gaiser

Cancer Res (2017) 77 (13_Supplement): 1438.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1438

Published: 01 July 2017

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Journal Articles

Abstract 2908: Single-cell genetic analysis of ductal carcinoma in situ with and without synchronous invasive breast cancer by multiplex FISH delineates specific patterns of tumor clonality and heterogeneity

Irianna Marie Torres, Leanora Hernandez, Jausheng Tzeng, Russell Schwartz, Alejandro Schaffer, Edward Gertz, Stephen Brower, Miguel Sanchez, Gert Auer, Kerstin Heselmeyer-Haddad, Ried Thomas

Cancer Res (2017) 77 (13_Supplement): 2908.

DOI: https://doi.org/10.1158/1538-7445.AM2017-2908

Published: 01 July 2017

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Journal Articles

Abstract 4387: The clonal composition of colorectal cancer cell lines is defined by the maintenance of specific genomic imbalances, not by ongoing chromosomal instability

Darawalee Wangsa, Madison Schiefer, Daniel Bronder, Hesed Padilla-Nash, Irianna Torres, Lidia Warner, Yue Hu, E Michael Gertz, Russell Schwartz, Alejandro A. Schäffer, Daniela Hirsch, Timo Gaiser, Rüdiger Meyer, Jordi Camps, Kerstin Heselmeyer-Haddad, Thomas Ried

Cancer Res (2017) 77 (13_Supplement): 4387.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4387

Published: 01 July 2017

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Journal Articles

Abstract 2182: Reconstructing evolutionary models of tumor progression from single-cell heterogeneity data

Salim A. Chowdhury, E. Michael Gertz, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Thomas Ried, Alejandro Schaeffer, Russell Schwartz

Cancer Res (2015) 75 (15_Supplement): 2182.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2182

Published: 01 August 2015

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Journal Articles

Abstract 4833: Single-cell genetic analysis reveals insights into clonal development of cervical cancer and confirms TERC as an early and dominant aberration

Leanora S. Hernandez, Amanda Bradley, Timo Gaiser, Sonia Andersson, E. Michael Gertz, Salim A. Chowdhury, Russel Schwartz, Alejandro Schäffer, Kerstin Heselmeyer-Haddad, Thomas Ried

Cancer Res (2015) 75 (15_Supplement): 4833.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4833

Published: 01 August 2015

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Journal Articles

Abstract 5338: Inferring evolutionary models of tumor progression from single-cell heterogeneity data

Salim A. Chowdhury, Ayshwarya Subramanian, Alejandro A. Schäffer, Stanley E. Shackney, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Thomas Ried, Russell Schwartz

Cancer Res (2014) 74 (19_Supplement): 5338.

DOI: https://doi.org/10.1158/1538-7445.AM2014-5338

Published: 01 October 2014

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Abstract 2895: Phylogenetic models of tumor progression from fluorescence in situ hybridization (FISH) data on many single cells of a solid tumor.

Salim A. Chowdhury, Alejandro A. Schäffer, Stanley E. Shackney, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Thomas Ried, Russell Schwartz

Cancer Res (2013) 73 (8_Supplement): 2895.

DOI: https://doi.org/10.1158/1538-7445.AM2013-2895

Published: 15 April 2013

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Journal Articles

Abstract 2107: Clonal patterns of chromosomal aberrations in cervical cancers and precursor lesions

Amanda Bradley, Kerstin Heselmeyer-Haddad, Timo Gaiser, Woei-Jyh Lee, Alejandro A. Schaffer, Sonia Andersson, Thomas Ried

Cancer Res (2012) 72 (8_Supplement): 2107.

DOI: https://doi.org/10.1158/1538-7445.AM2012-2107

Published: 15 April 2012

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Journal Articles

Abstract 333: FISH markers in oral tongue squamous cell carcinoma

Darawalee Wangsa, Michael Ryott, Göran Elmberger, Alejandro A. Schäffer, Gert Auer, Elisabeth Åvall Lundqvist, Eva Munck-Wikland, Thomas Ried, Kerstin Heselmeyer-Haddad

Cancer Res (2010) 70 (8_Supplement): 333.

DOI: https://doi.org/10.1158/1538-7445.AM10-333

Published: 15 April 2010

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Abstract 1757: Patterns of clonal chromosomal aberrations in invasive breast cancer compared to adjacent DCIS lesions detected by a ten-probe FISH panel

Lissa Y. Berroa-Garcia, Clarymar Ortiz-Melendez, Starsha Valentine Valentine, Semhar Tewelde, Rebecca Christensen, Kathleen Calzone, Alejandro Schaffer, Sheila Prindiville, Thomas Ried, Kerstin Heselmeyer-Haddad

Cancer Res (2010) 70 (8_Supplement): 1757.

DOI: https://doi.org/10.1158/1538-7445.AM10-1757

Published: 15 April 2010

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Journal Articles

Chromosomal amplifications detected by FISH markers to predict the neoplastic potential of cells in fine needle biopsies of abnormal nodules identified by spiral CT

Rajbir K. Gill, Arin Kramer, Madeline F. Vazquez, Kerstin Heselmeyer-Haddad, Thomas Ried, Claudia Henschke, David Yankelevitz, Jin Jen

Cancer Res (2005) 65 (9_Supplement): 854–855.

Published: 01 May 2005

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Journal Articles

Detection of Chromosomal Aneuploidies and Gene Copy Number Changes in Fine Needle Aspirates Is a Specific, Sensitive, and Objective Genetic Test for the Diagnosis of Breast Cancer

Kerstin Heselmeyer-Haddad, Nadia Chaudhri, Patricia Stoltzfus, Joseph C. Cheng, Kim Wilber, Larry Morrison, Gert Auer, Thomas Ried

Cancer Res (2002) 62 (8): 2365–2369.

Published: 01 April 2002

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NARROW

Abstract PO-106: Genomic heterogeneity and clonal dynamics of resistance evolution and metastatic progression in rectal cancer

Abstract 2498: miFISH single cell analysis as a potential tool to stratify the progression risk in patients with Atypical Ductal Hyperplasia (ADH)

Abstract 2189: Genomic dynamics in breast cancer progression analyzed by miFISH analysis

Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis

Abstract 2908: Single-cell genetic analysis of ductal carcinoma in situ with and without synchronous invasive breast cancer by multiplex FISH delineates specific patterns of tumor clonality and heterogeneity

Abstract 4387: The clonal composition of colorectal cancer cell lines is defined by the maintenance of specific genomic imbalances, not by ongoing chromosomal instability

Abstract 2182: Reconstructing evolutionary models of tumor progression from single-cell heterogeneity data

Abstract 4833: Single-cell genetic analysis reveals insights into clonal development of cervical cancer and confirms TERC as an early and dominant aberration

Abstract 5338: Inferring evolutionary models of tumor progression from single-cell heterogeneity data

Abstract 2895: Phylogenetic models of tumor progression from fluorescence in situ hybridization (FISH) data on many single cells of a solid tumor.

Abstract 2107: Clonal patterns of chromosomal aberrations in cervical cancers and precursor lesions

Abstract 333: FISH markers in oral tongue squamous cell carcinoma

Abstract 1757: Patterns of clonal chromosomal aberrations in invasive breast cancer compared to adjacent DCIS lesions detected by a ten-probe FISH panel

Chromosomal amplifications detected by FISH markers to predict the neoplastic potential of cells in fine needle biopsies of abnormal nodules identified by spiral CT

Detection of Chromosomal Aneuploidies and Gene Copy Number Changes in Fine Needle Aspirates Is a Specific, Sensitive, and Objective Genetic Test for the Diagnosis of Breast Cancer

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