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Kenneth Steadman
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Journal Articles

Abstract 421: PLX-3618, a potent, selective monovalent BRD4 degrader demonstrates activity in models of prostate cancer

Kenneth Steadman, Gregory S. Parker, Geoffray Leriche, Sarah Fish, Julia Toth, Mary E. Spalding, Elizabeth Daniele, Aleksandar Jamborcic, Xiaoming Li, E Adam Kallel, Farhana Barmare, Kenneth Chng, Erika Green, Michael Hocker, Elliot Imler, Yi Zhang, Peggy A. Thompson, Simon Bailey
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 421.
https://doi.org/10.1158/1538-7445.AM2022-421
Published: 15 June 2022
View article titled, Abstract 421: PLX-3618, a potent, selective monovalent BRD4 degrader demonstrates activity in models of prostate cancer
Journal Articles

Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential

Mariana Reis-Sobreiro, Jie-Fu Chen, Tatiana Novitskaya, Sungyong You, Samantha Morley, Kenneth Steadman, Navjot Kaur Gill, Adel Eskaros, Mirja Rotinen, Chia-Yi Chu, Leland W.K. Chung, Hisashi Tanaka, Wei Yang, Beatrice S. Knudsen, Hsian-Rong Tseng, Amy C. Rowat, Edwin M. Posadas, Andries Zijlstra, Dolores Di Vizio, Michael R. Freeman
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (21): 6086–6097.
https://doi.org/10.1158/0008-5472.CAN-18-0608
Published: 01 November 2018
View article titled, Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential
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Includes: Multimedia, Supplementary data
Journal Articles

Abstract 3320: Head & neck cancer stem cells express drug resistance transporters but do not display a resistant phenotype

Kenneth Steadman, Robert Robey, Karen Creswell, Rebecca Slack, John Deeken
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3320.
https://doi.org/10.1158/1538-7445.AM10-3320
Published: 15 April 2010
View article titled, Abstract 3320: Head & neck cancer stem cells express drug resistance transporters but do not display a resistant phenotype
Journal Articles

Abstract #2892: Characterizing the pharmacogenetic pathway of cisplatin and carboplatin in the NCI 60 cancer cell lines

John Deeken, Anne-Michelle Noone, Kenneth Steadman, Benjamin Masterman, Xin Li, Françoise Seillier-Moiseiwitsch
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2892.
Published: 01 May 2009
View article titled, Abstract #2892: Characterizing the pharmacogenetic pathway of cisplatin and carboplatin in the NCI 60 cancer cell lines
Journal Articles

Pharmacokinetic and biomarker analysis in a phase II trial of the HDAC inhibitor romidepsin, FK228

Richard Piekarz, Erin Gardner, Zhirong Zhan, Victoria Luchenko, Seth Steinberg, David Liewehr, Kenneth Steadman, Robin Frye, William Figg, Miles Prince, Steve Allen, Jasmine Zain, Mark Kirschbaum, Susan Bates
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5831.
Published: 01 May 2008
View article titled, Pharmacokinetic and biomarker analysis in a phase II trial of the HDAC inhibitor romidepsin, FK228
Journal Articles

Bisindolylmaleimide and indolocarbazole protein kinase (PK) inhibitors reverse ABCG2-mediated drug transport and resistance

Robert W. Robey, Suneet Shukla, Kenneth Steadman, Suresh V. Ambudkar, Susan E. Bates
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 146.
Published: 15 April 2006
View article titled, Bisindolylmaleimide and indolocarbazole protein kinase (PK) inhibitors reverse ABCG2-mediated drug transport and resistance
Journal Articles

Using multicellullar spheroids as a model of intrinsic drug resistance

Kenneth Steadman, Wilfred D. Stein, Thomas Litman, Sarah K. Dutcher, Susan E. Bates
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1197.
Published: 01 May 2005
View article titled, Using multicellullar spheroids as a model of intrinsic drug resistance
Journal Articles

Phase II trial of depsipeptide in patients with T-cell lymphoma: Review of responses and surrogate marker analysis

Richard L. Piekarz, Robin Frye, Zhirong Zhan, Robert W. Robey, Kenneth Steadman, Alex Sparreboom, Tito Fojo, John Wright, William D. Figg, Susan E. Bates
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 937.
Published: 01 May 2005
View article titled, Phase II trial of depsipeptide in patients with T-cell lymphoma: Review of responses and surrogate marker analysis
Journal Articles

Transcriptional therapy for neuroblastoma (NB) and ewing’s sarcoma (ES)- the HDAC inhibitor depsipeptide decreases N-myc (NB) and c-myc (ES) levels and inhibits growth in both tumors

Jyoti Panicker, Kenneth Steadman, Susan Bates, Carol J. Thiele
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 693.
Published: 01 May 2005
View article titled, Transcriptional therapy for neuroblastoma (NB) and ewing’s sarcoma (ES)- the HDAC inhibitor depsipeptide decreases N-myc (NB) and c-myc (ES) levels and inhibits growth in both tumors
Journal Articles

Use of pheophorbide a, an ABCG2 specific substrate, to probe for ABCG2 expression and function

Robert W. Robey, Kenneth Steadman, Orsolya Polgar, Margaret Blayney, Prakash Mistry, Susan E. Bates
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 117.
Published: 01 April 2004
View article titled, Use of pheophorbide a, an ABCG2 specific substrate, to probe for ABCG2 expression and function
Journal Articles

Pheophorbide a Is a Specific Probe for ABCG2 Function and Inhibition

Robert W. Robey, Kenneth Steadman, Orsolya Polgar, Kuniaki Morisaki, Margaret Blayney, Prakash Mistry, Susan E. Bates
Journal: Cancer Research
Cancer Res (2004) 64 (4): 1242–1246.
https://doi.org/10.1158/0008-5472.CAN-03-3298
Published: 18 February 2004
View article titled, Pheophorbide a Is a Specific Probe for ABCG2 Function and Inhibition
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