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Abstract 897: Targeting ALDH1A1 and stemness regulatory networks in ovarian cancer

Vaishnavi Muralikrishnan, Fang Fang, Tyler C. Given, Ram Podicheti, Douglas B. Rusch, Thomas D. Hurley, Kenneth P. Nephew

Cancer Res (2022) 82 (12_Supplement): 897.

DOI: https://doi.org/10.1158/1538-7445.AM2022-897

Published: 15 June 2022

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Journal Articles

The Ratio of Toxic-to-Nontoxic miRNAs Predicts Platinum Sensitivity in Ovarian Cancer

Monal Patel, Yinu Wang, Elizabeth T. Bartom, Rohin Dhir, Kenneth P. Nephew, Daniela Matei, Andrea E. Murmann, Ernst Lengyel, Marcus E. Peter

Cancer Res (2021) 81 (15): 3985–4000.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-0953

Published: 01 August 2021

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Includes: Supplementary data

Journal Articles

Abstract 3095: Targeting ALDH1A1 and regulatory networks that support stemness in ovarian cancer cells

Vaishnavi Muralikrishnan, Kenneth P. Nephew, Thomas D. Hurley

Cancer Res (2021) 81 (13_Supplement): 3095.

DOI: https://doi.org/10.1158/1538-7445.AM2021-3095

Published: 01 July 2021

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Journal Articles

Abstract LT020: Cancer associated fibroblasts in the tumor microenvironment maintain ovarian cancer stem cells through non-canonical Wnt5a signaling

Yiming Fang, Xue Xiao, Ji Wang, Subramanyam Dasari, Kenneth P. Nephew, Dmitriy Zamarin, Anirban K. Mitra

Cancer Res (2021) 81 (5_Supplement): LT020.

DOI: https://doi.org/10.1158/1538-7445.TME21-LT020

Published: 01 March 2021

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Journal Articles

How Epigenetic Therapy Beats Adverse Genetics in Monosomy Karyotype AML

Heather M. O'Hagan, Feyruz V. Rassool, Kenneth P. Nephew

Cancer Res (2021) 81 (4): 813–815.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-4108

Published: 15 February 2021

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Journal Articles

Turning Up the Heat on the Pancreatic Tumor Microenvironment by Epigenetic Priming

Kenneth P. Nephew

Cancer Res (2020) 80 (21): 4610–4611.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-3097

Published: 03 November 2020

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Journal Articles

EZH2-Mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells

Xingyue Zong, Weini Wang, Ali Ozes, Fang Fang, George E. Sandusky, Kenneth P. Nephew

Cancer Res (2020) 80 (20): 4371–4385.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-0458

Published: 15 October 2020

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Includes: Supplementary data

Journal Articles

Epigenetic Attire in Ovarian Cancer: The Emperor's New Clothes

Daniela Matei, Kenneth P. Nephew

Cancer Res (2020) 80 (18): 3775–3785.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-3837

Published: 15 September 2020

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Journal Articles

Abstract 1403: HOTAIR functions through NF-κB pathway in regulating ovarian cancer stem cells

Weini Wang, Fang Fang, Ali R. Özeş, Kenneth P. Nephew

Cancer Res (2020) 80 (16_Supplement): 1403.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1403

Published: 15 August 2020

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Journal Articles

Abstract 498: Targeting EZH2/DAB2IP/C-JUN axis in ovarian cancer stem cells

Xingyue Zong, Ali Ozes, Weini Wang, Fang Fang, Kenneth P. Nephew

Cancer Res (2020) 80 (16_Supplement): 498.

DOI: https://doi.org/10.1158/1538-7445.AM2020-498

Published: 15 August 2020

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Journal Articles

Abstract P2-06-01: Intrinsic transcriptomic differences of luminal progenitors and mature luminal cells of the normal breast

Fang Fang, Poornima Bhat-Nakshatri, Manjushree Anjanappa, Dough Rusch, Aaron Buechlein, Dave Miller, Kenneth P Nephew, Harikrishna Nakshatri

Cancer Res (2020) 80 (4_Supplement): P2-06-01.

DOI: https://doi.org/10.1158/1538-7445.SABCS19-P2-06-01

Published: 15 February 2020

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Journal Articles

Abstract 3685: HOTAIR regulation and functionality in ovarian cancer stem cells

Weini Wang, Fang Fang, Ali Ozes, Kenneth P. Nephew

Cancer Res (2019) 79 (13_Supplement): 3685.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3685

Published: 01 July 2019

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Journal Articles

Abstract 4319: Epigenetic reprogramming associated with BRCA1 loss of function in ovarian cancer induces enhanced interferon gamma signaling

Horacio Cardenas, Jessica Thomes Pepin, Guanglong Jiang, Salvatore Condello, Kenneth P. Nephew, Yunlong Liu, Daniela Matei

Cancer Res (2018) 78 (13_Supplement): 4319.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4319

Published: 01 July 2018

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Journal Articles

Genomic and Epigenomic Signatures in Ovarian Cancer Associated with Resensitization to Platinum Drugs

Fang Fang, Horacio Cardenas, Hao Huang, Guanglong Jiang, Susan M. Perkins, Chi Zhang, Harold N. Keer, Yunlong Liu, Kenneth P. Nephew, Daniela Matei

Cancer Res (2018) 78 (3): 631–644.

DOI: https://doi.org/10.1158/0008-5472.CAN-17-1492

Published: 31 January 2018

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Includes: Supplementary data

Journal Articles

Abstract 4675: Novel combination therapy of DNA methyltransferase inhibitor guadecitabine (SGI-110) and PARP inhibitor talazoparib (BMN-673) for BRCA-proficient high-grade serous ovarian cancer

Nicholas Pulliam, Pietro Taverna, John Lyons, Kenneth P. Nephew

Cancer Res (2017) 77 (13_Supplement): 4675.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4675

Published: 01 July 2017

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Journal Articles

Abstract 4347: Epigenetic targeting of DNMT1 in adipocytes inhibits high-grade serous ovarian cancer cell migration and invasion through TIMP3 upregulation

Jessica Tang, Fang Fang, Aaron Buechlein, Pietro Taverna, Kenneth P. Nephew

Cancer Res (2017) 77 (13_Supplement): 4347.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4347

Published: 01 July 2017

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Journal Articles

Abstract 950: Bistable switching of c-KIT by estrogen-mediated ceRNA and epigenetic silencing of miR-193a predicts survival in ovarian cancer

Frank Hsueh-Che Cheng, Baltazar D. Aguda, Hon-Yi Lin, Je-Chiang Tsai, Marek Kochanczyk, Ru-Inn Lin, Jora M. J. Lin, Gary C. W. Chen, Cheng-Chang Chang, Hung-Cheng Lai, Kenneth P. Nephew, Tzy-Wei Hwang, Michael W. Y. Chan

Cancer Res (2016) 76 (14_Supplement): 950.

DOI: https://doi.org/10.1158/1538-7445.AM2016-950

Published: 15 July 2016

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Journal Articles

Abstract 4024: Epigenetic priming potentiates immune checkpoints inhibitors in ovarian cancer

Yu Qing, Salvatore Condello, Katie J. Meyer, Andrea Caperell-Grant, Kenneth P. Nephew, Daniela Matei

Cancer Res (2016) 76 (14_Supplement): 4024.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4024

Published: 15 July 2016

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Journal Articles

Abstract B2-09: A systems biology approach to understanding estrogen responsiveness in breast cancer cells using the MCF7 model

Ayesha N. Shajahan-Haq, Lang Li, Yunlong Liu, Lu Jin, David F. Miller, Jay Pilrose, Amrita K. Cheema, Simina M. Boca, Krithika Bhuvaneshwar, Subha Madhavan, Robert Clarke, Kenneth P. Nephew

Cancer Res (2015) 75 (22_Supplement_2): B2-09.

DOI: https://doi.org/10.1158/1538-7445.COMPSYSBIO-B2-09

Published: 15 November 2015

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Journal Articles

Abstract 2943: Novel combination therapy of DNMT inhibitor SGI-110 and PARP inhibitor BMN-673 (talazoparib) for BRCA-proficient ovarian cancer

Nicholas Pulliam, Pietro Taverna, John Lyons, Kenneth P. Nephew

Cancer Res (2015) 75 (15_Supplement): 2943.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2943

Published: 01 August 2015

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NARROW

Abstract 897: Targeting ALDH1A1 and stemness regulatory networks in ovarian cancer

The Ratio of Toxic-to-Nontoxic miRNAs Predicts Platinum Sensitivity in Ovarian Cancer

Abstract 3095: Targeting ALDH1A1 and regulatory networks that support stemness in ovarian cancer cells

Abstract LT020: Cancer associated fibroblasts in the tumor microenvironment maintain ovarian cancer stem cells through non-canonical Wnt5a signaling

How Epigenetic Therapy Beats Adverse Genetics in Monosomy Karyotype AML

Turning Up the Heat on the Pancreatic Tumor Microenvironment by Epigenetic Priming

EZH2-Mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells

Epigenetic Attire in Ovarian Cancer: The Emperor's New Clothes

Abstract 1403: HOTAIR functions through NF-κB pathway in regulating ovarian cancer stem cells

Abstract 498: Targeting EZH2/DAB2IP/C-JUN axis in ovarian cancer stem cells

Abstract P2-06-01: Intrinsic transcriptomic differences of luminal progenitors and mature luminal cells of the normal breast

Abstract 3685: HOTAIR regulation and functionality in ovarian cancer stem cells

Abstract 4319: Epigenetic reprogramming associated with BRCA1 loss of function in ovarian cancer induces enhanced interferon gamma signaling

Genomic and Epigenomic Signatures in Ovarian Cancer Associated with Resensitization to Platinum Drugs

Abstract 4675: Novel combination therapy of DNA methyltransferase inhibitor guadecitabine (SGI-110) and PARP inhibitor talazoparib (BMN-673) for BRCA-proficient high-grade serous ovarian cancer

Abstract 4347: Epigenetic targeting of DNMT1 in adipocytes inhibits high-grade serous ovarian cancer cell migration and invasion through TIMP3 upregulation

Abstract 950: Bistable switching of c-KIT by estrogen-mediated ceRNA and epigenetic silencing of miR-193a predicts survival in ovarian cancer

Abstract 4024: Epigenetic priming potentiates immune checkpoints inhibitors in ovarian cancer

Abstract B2-09: A systems biology approach to understanding estrogen responsiveness in breast cancer cells using the MCF7 model

Abstract 2943: Novel combination therapy of DNMT inhibitor SGI-110 and PARP inhibitor BMN-673 (talazoparib) for BRCA-proficient ovarian cancer

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