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Kenji Yokoi
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Journal Articles

Abstract 1007: Spatial, temporal and heterogeneous changes in transport phenotype in liver metastasis of breast cancer

Aygul Sadigova, Megumi Kai, Yan Ting Liu, Thao Nguyen, Chihiro Hashimoto, Kenji Yokoi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1007.
https://doi.org/10.1158/1538-7445.AM2022-1007
Published: 15 June 2022
View articletitled, Abstract 1007: Spatial, temporal and heterogeneous changes in transport phenotype in liver metastasis of breast cancer
Journal Articles

Abstract P1-06-04: Spatial, temporal and therapy dependent heterogeneity in transport phenotype of multiple liver metastases in murine breast cancer model

Thao Nguyen, Yan ting Liu, Arturas Ziemys, Shen Haifa, Kenji Yokoi
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-06-04.
https://doi.org/10.1158/1538-7445.SABCS21-P1-06-04
Published: 15 February 2022
View articletitled, Abstract P1-06-04: Spatial, temporal and therapy dependent heterogeneity in transport phenotype of multiple liver metastases in murine breast cancer model
Journal Articles

Abstract 2810: Effect of clone dependent difference in the metastatic tumor microenvironment of 4T1 breast cancer on anti-PDL1 antibody delivery & therapeutic efficacy

Yan Ting Liu, Thao Nguyen, Shreya Goel, Megumi Kai, Haifa Shen, Kenji Yokoi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2810.
https://doi.org/10.1158/1538-7445.AM2021-2810
Published: 01 July 2021
View articletitled, Abstract 2810: Effect of clone dependent difference in the metastatic tumor microenvironment of 4T1 breast cancer on anti-PDL1 antibody delivery & therapeutic efficacy
Journal Articles

Abstract PS18-42: Heterogeneous tumor microenvironment in metastatic breast cancer for insufficient anti-PDL1 IgG delivery and its efficacy

Yan ting Liu, Shreya Goel, Megumi Kai, Thao Nguyen, Kenji Yokoi
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS18-42.
https://doi.org/10.1158/1538-7445.SABCS20-PS18-42
Published: 15 February 2021
View articletitled, Abstract PS18-42: Heterogeneous tumor microenvironment in metastatic breast cancer for insufficient anti-PDL1 IgG delivery and its efficacy
Journal Articles

Abstract B39: Computational modeling of therapy using nanovectors altering macrophage subtypes to treat hypo-perfused tumor lesions

Fransisca Leonard, Louis T. Curtis, Elias Nassar, Xuewu Liu, Mauro Ferrari, Kenji Yokoi, Biana Godin, Hermann B. Frieboes
Journal: Cancer Research
Cancer Res (2017) 77 (2_Supplement): B39.
https://doi.org/10.1158/1538-7445.EPSO16-B39
Published: 16 January 2017
View articletitled, Abstract B39: Computational modeling of therapy using nanovectors altering macrophage subtypes to treat hypo-perfused tumor lesions
Journal Articles

Abstract 1324: Enhancing therapeutic efficacy of albumin bound paclitaxel in breast cancer liver metastasis by homing to tumor associated macrophages: In vitro, in vivo and in silico studies

Fransisca Leonard, Curtis T. Louis, Pooja Yesantharao, Tomonori Tanei, Jenolyn F. Alexander, Liu Xuewu, Ferrari Mauro, Kenji Yokoi, Hermann B. Frieboes, Biana Godin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1324.
https://doi.org/10.1158/1538-7445.AM2016-1324
Published: 15 July 2016
View articletitled, Abstract 1324: Enhancing therapeutic efficacy of albumin bound paclitaxel in breast cancer liver metastasis by homing to tumor associated macrophages: In vitro, in vivo and in silico studies
Journal Articles

Abstract 1577: Thrombus formation inside liver metastasis of breast cancer by pegylated liposomal doxorubicin

Megumi Kai, Yan Ting Liu, Mauro Ferrari, Kenji Yokoi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1577.
https://doi.org/10.1158/1538-7445.AM2016-1577
Published: 15 July 2016
View articletitled, Abstract 1577: Thrombus formation inside liver metastasis of breast cancer by pegylated liposomal doxorubicin
Journal Articles

Redirecting Transport of Nanoparticle Albumin-Bound Paclitaxel to Macrophages Enhances Therapeutic Efficacy against Liver Metastases

Tomonori Tanei, Fransisca Leonard, Xuewu Liu, Jenolyn F. Alexander, Yuki Saito, Mauro Ferrari, Biana Godin, Kenji Yokoi
Journal: Cancer Research
Cancer Res (2016) 76 (2): 429–439.
https://doi.org/10.1158/0008-5472.CAN-15-1576
Published: 14 January 2016
View articletitled, Redirecting Transport of Nanoparticle Albumin-Bound Paclitaxel to Macrophages Enhances Therapeutic Efficacy against Liver Metastases
Open the PDF for Redirecting Transport of Nanoparticle Albumin-Bound Paclitaxel to Macrophages Enhances Therapeutic Efficacy against Liver Metastases in another window
Includes: Supplementary data
Journal Articles

Abstract 403: Acquired resistance to pegylated liposomal doxorubicin

Megumi Kai, Tomonori Tanei, Yan Ting Liu, Yuki Saito, Mauro Ferrari, Kenji Yokoi
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 403.
https://doi.org/10.1158/1538-7445.AM2015-403
Published: 01 August 2015
View articletitled, Abstract 403: Acquired resistance to pegylated liposomal doxorubicin
Journal Articles

Abstract 2833: Enhanced therapeutic efficacy of a combination of gemcitabine and albumin-bound paclitaxel in multistage nanovectors in pancreatic ductal adenocarcinoma: Evaluation of transport phenomena

Carlotta Borsoi, Kenji Yokoi, Fransisca Leonard, Mauro Ferrari, Biana Godin Vilentchouk
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2833.
https://doi.org/10.1158/1538-7445.AM2015-2833
Published: 01 August 2015
View articletitled, Abstract 2833: Enhanced therapeutic efficacy of a combination of gemcitabine and albumin-bound paclitaxel in multistage nanovectors in pancreatic ductal adenocarcinoma: Evaluation of transport phenomena
Journal Articles

Abstract P1-07-13: Extramedullary hematopoiesis aids initiation of cancer metastasis

Kenji Yokoi, Tomonori Tanei, Megumi Kai, Yuki Saito, Yan Ting Liu, Mauro Ferrari
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P1-07-13.
https://doi.org/10.1158/1538-7445.SABCS14-P1-07-13
Published: 01 May 2015
View articletitled, Abstract P1-07-13: Extramedullary hematopoiesis aids initiation of cancer metastasis
Journal Articles

RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells

Matthias Ilmer, Alejandro Recio Boiles, Ivonne Regel, Kenji Yokoi, Christoph W. Michalski, Ignacio I. Wistuba, Jaime Rodriguez, Eckhard Alt, Jody Vykoukal
Journal: Cancer Research
Cancer Res (2015) 75 (9): 1883–1896.
https://doi.org/10.1158/0008-5472.CAN-14-1327
Published: 30 April 2015
View articletitled, RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells
Open the PDF for RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 2986: Novel vascular targeting strategy using pegylated liposomal doxorubicin to increase drug accumulation to tumor site and therapeutic efficacy

Kenji Yokoi, Tomonori Tanei, Yuki Saito, Mauro Ferrari
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2986.
https://doi.org/10.1158/1538-7445.AM2014-2986
Published: 01 October 2014
View articletitled, Abstract 2986: Novel vascular targeting strategy using pegylated liposomal doxorubicin to increase drug accumulation to tumor site and therapeutic efficacy
Journal Articles

Capillary-Wall Collagen as a Biophysical Marker of Nanotherapeutic Permeability into the Tumor Microenvironment

Kenji Yokoi, Milos Kojic, Miljan Milosevic, Tomonori Tanei, Mauro Ferrari, Arturas Ziemys
Journal: Cancer Research
Cancer Res (2014) 74 (16): 4239–4246.
https://doi.org/10.1158/0008-5472.CAN-13-3494
Published: 13 August 2014
View articletitled, Capillary-Wall Collagen as a Biophysical Marker of Nanotherapeutic Permeability into the Tumor Microenvironment
Open the PDF for Capillary-Wall Collagen as a Biophysical Marker of Nanotherapeutic Permeability into the Tumor Microenvironment in another window
Journal Articles

Abstract 2148: Novel therapy of liver metastases of cancer using Abraxane loaded into Multi-Stage Nanovector.

Tomonori Tanei, Mauro Ferrari, Biana Godin, Kenji Yokoi
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2148.
https://doi.org/10.1158/1538-7445.AM2013-2148
Published: 15 April 2013
View articletitled, Abstract 2148: Novel therapy of liver metastases of cancer using Abraxane loaded into Multi-Stage Nanovector.
Journal Articles

Abstract 4973: Tumor type and organ type dependent differences of vascular permeability to pegylated liposomal doxorubicin.

Kenji Yokoi, Tomonori Tanei, Biana Godin, Anne van de Ven, Jenolyn Alexander, Mauro Ferrari
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4973.
https://doi.org/10.1158/1538-7445.AM2013-4973
Published: 15 April 2013
View articletitled, Abstract 4973: Tumor type and organ type dependent differences of vascular permeability to pegylated liposomal doxorubicin.
Journal Articles

Abstract 2862: Deregulated GSK3β sustains gastrointestinal cancer cells by modulating hTERT and telomerase

Toshinari Minamoto, Wei Mai, Satoru Kyo, Abbas Shakoori, Katsuyoshi Miyashita, Kenji Yokoi, Takeo Shimasaki, Yoshiharu Motoo, Kazuyuki Kawakami
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2862.
https://doi.org/10.1158/1538-7445.AM2012-2862
Published: 15 April 2012
View articletitled, Abstract 2862: Deregulated GSK3β sustains gastrointestinal cancer cells by modulating hTERT and telomerase
Journal Articles

Abstract 2453: Overcoming transport barriers in liver metastasis with multi-stage nanovectors (MSV)

Kenji Yokoi, Anne Van de Ven, Jenolyn F. Alexander, Litao Bai, Xuewu Liu, Isaiah J. Fidler, Mauro Ferrari, Biana Godin
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2453.
https://doi.org/10.1158/1538-7445.AM2012-2453
Published: 15 April 2012
View articletitled, Abstract 2453: Overcoming transport barriers in liver metastasis with multi-stage nanovectors (MSV)
Journal Articles

Abstract 379: Target delivery of multistage nanovectors to tumor-associated macrophages and endothelial cells in orthotopic model of human pancreatic cancer

Kenji Yokoi, Biana Godin, Jenolyn F. Alexander, Tony Hu, Xuewu Liu, Isaiah Fidler, Mauro Ferrari
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 379.
https://doi.org/10.1158/1538-7445.AM2011-379
Published: 15 April 2011
View articletitled, Abstract 379: Target delivery of multistage nanovectors to tumor-associated macrophages and endothelial cells in orthotopic model of human pancreatic cancer
Journal Articles

Simultaneous Inhibition of EGFR, VEGFR, and Platelet-Derived Growth Factor Receptor Signaling Combined with Gemcitabine Produces Therapy of Human Pancreatic Carcinoma and Prolongs Survival in an Orthotopic Nude Mouse Model

Kenji Yokoi, Takamitsu Sasaki, Corazon D. Bucana, Dominic Fan, Cheryl H. Baker, Yasuhiko Kitadai, Toshio Kuwai, James L. Abbruzzese, Isaiah J. Fidler
Journal: Cancer Research
Cancer Res (2005) 65 (22): 10371–10380.
https://doi.org/10.1158/0008-5472.CAN-05-1698
Published: 15 November 2005
View articletitled, Simultaneous Inhibition of EGFR, VEGFR, and Platelet-Derived Growth Factor Receptor Signaling Combined with Gemcitabine Produces Therapy of Human Pancreatic Carcinoma and Prolongs Survival in an Orthotopic Nude Mouse Model
Open the PDF for Simultaneous Inhibition of EGFR, VEGFR, and Platelet-Derived Growth Factor Receptor Signaling Combined with Gemcitabine Produces Therapy of Human Pancreatic Carcinoma and Prolongs Survival in an Orthotopic Nude Mouse Model in another window