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Kenji Shimizu
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Journal Articles

Abstract 1158: Multiple molecular targeting effects by miR-7 in EGFR tyrosine kinase inhibitor-resistant lung cancer xenograft models

Kammei Rai, Nagio Takigawa, Sachio Ito, Katsuyuki Kiura, Tateji Yasuda, Kenji Shimizu, Mitsune Tanimoto
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1158.
https://doi.org/10.1158/1538-7445.AM2011-1158
Published: 15 April 2011
View articletitled, Abstract 1158: Multiple molecular targeting effects by miR-7 in EGFR tyrosine kinase inhibitor-resistant lung cancer xenograft models
Journal Articles

Abstract LB-246: Identification of novel direct targets of miR-19a in MCF-7 breast cancer cells

Hirotaka Kanzaki, Mamoru Ouchida, Sachio Ito, Seiji Tamaru, Hiroko Hanafusa, Yoshimi Jitsumori, Takashi Oka, Kenji Shimizu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-246.
https://doi.org/10.1158/1538-7445.AM10-LB-246
Published: 15 April 2010
View articletitled, Abstract LB-246: Identification of novel direct targets of miR-19a in MCF-7 breast cancer cells
Journal Articles

Abstract 4041: Lipofection of the designed plasmid expressing microRNA-7 has antitumor effect in gefitinib-resistant lung adenocarcinoma in vivo

Kammei Rai, Nagio Takigawa, Sachio Ito, Hiromi Kashihara, Eiki Ichihara, Katsuyuki Kiura, Tatsuji Yasuda, Kenji Shimizu, Mitsune Tanimoto
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4041.
https://doi.org/10.1158/1538-7445.AM10-4041
Published: 15 April 2010
View articletitled, Abstract 4041: Lipofection of the designed plasmid expressing microRNA-7 has antitumor effect in gefitinib-resistant lung adenocarcinoma in vivo
Journal Articles

Abstract #2649: Identification of novel target proteins for miR-17-92 cluster by proteomic analysis

Hirotaka Kanzaki, Mamoru Ouchida, Sachio Ito, Seiji Tamaru, Hiroko Hanafusa, Kenji Shimizu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2649.
Published: 01 May 2009
View articletitled, Abstract #2649: Identification of novel target proteins for miR-17-92 cluster by proteomic analysis
Journal Articles

Abstract #1396: MicroRNA-7 downregulates epidermal growth factor receptor in both gefitinib-sensitive and -resistant lung adenocarcinoma cells

Kammei Rai, Nagio Takigawa, Sachio Ito, Katsuyuki Kiura, Masayuki Yasugi, Daijiro Harada, Nobuaki Ochi, Tatsuji Yasuda, Kenji Shimizu, Mitsune Tanimoto
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1396.
Published: 01 May 2009
View articletitled, Abstract #1396: MicroRNA-7 downregulates epidermal growth factor receptor in both gefitinib-sensitive and -resistant lung adenocarcinoma cells
Journal Articles

Proteomics based analysis of invasion-related proteins in malignant gliomas

Hirotaka Kanzaki, Tomoko Maruo, Tomotsugu Ichikawa, Satoshi Inoue, Hiroshi Kosaka, Kouishi Yoshida, Hirokazu Kambara, Isao Date, Mamoru Ouchida, Kenji Shimizu
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3933.
Published: 01 May 2008
View articletitled, Proteomics based analysis of invasion-related proteins in malignant gliomas
Journal Articles

MET amplification in untreated lung cancer patients with EGFR activating mutation, but without T790M mutation, contributes to resistance to gefitinib

Takafumi Kubo, Hiromasa Yamamoto, William Lockwood, Tetsuya Fujii, Mamoru Ouchida, Junichi Soh, Nagio Takigawa, Katsuyuki Kiura, John Minna, Adi Gazdar, Wan Lam, Kenji Shimizu, Hiroshi Date, Shinichi Toyooka
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-156.
Published: 01 May 2008
View articletitled, MET amplification in untreated lung cancer patients with EGFR activating mutation, but without T790M mutation, contributes to resistance to gefitinib
Journal Articles

Detection of single nucleotide polymorphism in the PDCD5 gene in Japanese non-small cell lung cancer patients.

Shinichi Toyooka, Kei Nanba, Hiromasa Yamamoto, Naruyuki Kobayashi, Keitaro Matsuo, Kenji Shimizu, Hiroshi Date
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1904.
Published: 01 May 2008
View articletitled, Detection of single nucleotide polymorphism in the PDCD5 gene in Japanese non-small cell lung cancer patients.
Journal Articles

Epigenetic abnormalities associated with gene silencing induce onset and progression of lymphomas/leukemias

Takashi Oka, Yoko Nakatani, Takami Kondo, Hiaki Sato, Kana Washio, Masayuki Takano, Ichiro Murakami, Nobuya Ohara, Kiyoshi Takahashi, Mamoru Ouchida, Koichi Ohshima, Mitsune Tanimoto, Kenji Shimizu, Atae Utsunomiya, Tadashi Yoshino
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1126.
Published: 01 May 2007
View articletitled, Epigenetic abnormalities associated with gene silencing induce onset and progression of lymphomas/leukemias
Journal Articles

Molecular analysis of the EGFR pathway in head and neck squamous cell carcinomas

Mehmet Gunduz, Mahmoud AL Sheikh Ali, Hitoshi Nagatsuka, Esra Gunduz, Beyhan Cengiz, Levent Beder, Kadir Demircan, Tomoki Yamatsuji, Kunihiro Fukushima, Ryo Tamamura, Yoshio Naomoto, Kenji Shimizu, Noriyuki Nagai
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5241.
Published: 01 May 2007
View articletitled, Molecular analysis of the EGFR pathway in head and neck squamous cell carcinomas
Journal Articles

mRNA expression analysis of ADAMTS-aggrecanases in head and neck cancers

Kadir Demircan, Esra Gunduz, Mehmet Gunduz, Satoshi Hirohata, Levent Beder, Hitoshi Nagatsuka, Beyhan Cengiz, Toshitaka Oohashi, Masafumi Kataoka, Omer Hatipoglu, Kursat Yaykasli, Kenji Shimizu, Yoshifumi Ninomiya
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 554.
Published: 01 May 2007
View articletitled, mRNA expression analysis of ADAMTS-aggrecanases in head and neck cancers
Journal Articles

Molecular analysis of ING4 and its splicing variants in oral cancer

Esra Gunduz, Mehmet Gunduz, Hitoshi Nagatsuka, Beyhan Cengiz, Levent Beder, Kadir Demircan, Naila Mahmut, Phuu Han, Kunihiro Fukushima, Yoshio Naomoto, Kenji Shimizu, Noriyuki Nagai
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3692.
Published: 01 May 2007
View articletitled, Molecular analysis of ING4 and its splicing variants in oral cancer
Journal Articles

CpG island methylator phenotype (CIMP) promotes the progression of adult T-cell leukemia/lymphoma (ATLL).

Hiaki Sato, Takashi Oka, Yoko Nakatani, Takami Kondo, Kana Washio, Masayuki Takano, Nobuya Ohara, Mamoru Ouchida, Koichi Ohshima, Kenji Shimizu, Mitsune Tanimoto, Kiyoshi Takahashi, Atae Utsunomiya, Tadashi Yoshino
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2880.
Published: 01 May 2007
View articletitled, CpG island methylator phenotype (CIMP) promotes the progression of adult T-cell leukemia/lymphoma (ATLL).
Journal Articles

Association of the RAD18 gene Arg302Gln polymorphism with human non-small-cell lung cancer risk

Hirotaka Kanzaki, Mamoru Ouchida, Hiroko Hanafusa, Hiromasa Yamamoto, Hiromitsu Suzuki, Motoi Aoe, Kazue Imai, Mitsuya Ito, Junji Matsuoka, Hiroshi Date, Kei Nakachi, Kenji Shimizu
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4256.
Published: 01 May 2007
View articletitled, Association of the RAD18 gene Arg302Gln polymorphism with human non-small-cell lung cancer risk
Journal Articles

Molecular pathological analysis of the protein tyrosine phosphatase: SHP1 gene in the pathogenesis of lymphoma and leukemias

Takashi Oka, Yoko Nakatani, Takami Kondo, Hiaki Sato, Kana Washio, Masayuki Takano, Ichirou Murakami, Yuriko Nishikawa, Mamoru Ouchida, Nobuya Ohara, Kiyoshi Takahashi, Kazuhiko Hayashi, Mitsune Tanimoto, Kenji Shimizu, Tadashi Yoshino
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 383.
Published: 15 April 2006
View articletitled, Molecular pathological analysis of the protein tyrosine phosphatase: SHP1 gene in the pathogenesis of lymphoma and leukemias
Journal Articles

Abberant DNA methylation in the progression of adult T cell leukemia/lymphoma (ATLL)

Hiaki Sato, Takashi Oka, Yoko Nakatani, Takami Kondo, Masayuki Takano, Nobuya Ohara, Mamoru Ouchida, Kouichi Oshima, Kenji Shimizu, Mitsune Tanimoto, Kiyoshi Tkahashi, Yoshino Tadashi
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 6–7.
Published: 15 April 2006
View articletitled, Abberant DNA methylation in the progression of adult T cell leukemia/lymphoma (ATLL)
Journal Articles

Inactivation of p57Kip2 by promoter hypermethylation in non-small cell lung cancers

Masaaki Yano, Shinichi Toyooka, Mamoru Ouchida, Hideaki Dote, Kazunori Tsukuda, Motoi Aoe, Kenji Shimizu, Nobuyoshi Shimizu
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 969.
Published: 01 April 2004
View articletitled, Inactivation of p57Kip2 by promoter hypermethylation in non-small cell lung cancers
Journal Articles

Gene Silencing of the Tyrosine Phosphatase SHP1 Gene by Aberrant Methylation in Leukemias/Lymphomas

Takashi Oka, Mamoru Ouchida, Maho Koyama, Yoichiro Ogama, Shinichi Takada, Yoko Nakatani, Takehiro Tanaka, Tadashi Yoshino, Kazuhiko Hayashi, Nobuya Ohara, Eisaku Kondo, Kiyoshi Takahashi, Junjiro Tsuchiyama, Mitsune Tanimoto, Kenji Shimizu, Tadaatsu Akagi
Journal: Cancer Research
Cancer Res (2002) 62 (22): 6390–6394.
Published: 15 November 2002
View articletitled, Gene Silencing of the Tyrosine Phosphatase SHP1 Gene by Aberrant Methylation in Leukemias/Lymphomas
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Journal Articles

High Frequency of Low-Level Microsatellite Instability in Early Colorectal Cancer

Takeshi Kambara, Nagahide Matsubara, Hitoshi Nakagawa, Kenji Notohara, Takeshi Nagasaka, Tadashi Yoshino, Hiroshi Isozaki, Gerald B. Sharp, Kenji Shimizu, Jeremy Jass, Noriaki Tanaka
Journal: Cancer Research
Cancer Res (2001) 61 (21): 7743–7746.
Published: 01 November 2001
View articletitled, High Frequency of Low-Level Microsatellite Instability in Early Colorectal Cancer
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Journal Articles

Genomic Structure of the Human ING1 Gene and Tumor-specific Mutations Detected in Head and Neck Squamous Cell Carcinomas

Mehmet Gunduz, Mamoru Ouchida, Kunihiro Fukushima, Hiroko Hanafusa, Tsutomu Etani, Shinji Nishioka, Kazunori Nishizaki, Kenji Shimizu
Journal: Cancer Research
Cancer Res (2000) 60 (12): 3143–3146.
Published: 15 June 2000
View articletitled, Genomic Structure of the Human ING1 Gene and Tumor-specific Mutations Detected in Head and Neck Squamous Cell Carcinomas
Open the PDF for Genomic Structure of the Human ING1 Gene and Tumor-specific Mutations Detected in Head and Neck Squamous Cell Carcinomas in another window