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Kelly K. Hunt
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Journal Articles

Abstract 3107: Identifying therapeutic vulnerabilities in HR-positive, HER2-negative advanced breast cancer patient-derived xenograft models refractory to CDK4/6 inhibition

Nicole M. Kettner, Juliana Navarro-Yepes, Tuyen N. Bui, Xiayu Rao, Jing Wang, Funda Meric-Bernstam, Kelly K. Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3107.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3107
Published: 15 June 2022
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Abstract 1268: Early proliferative response via [18]FLT-PET/CT and serum TK1 activity are predictive biomarkers for synergistic effect of sequential cell cycle targeted therapy in sarcoma

Tuyen Duong Nguyen, Marc A. Pina, Yan Wang, Cansu Karakas, Tuyen N. Bui, Osama Mawlawi, Alexander J. Lazar, Davis R. Ingram, Peter J. Hougton, Kelly K. Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1268.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1268
Published: 15 June 2022
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Journal Articles

Abstract 1798: Mechanisms of acquired resistance to palbociclib reveals pathways of response to abemaciclib

Juliana Navarro-Yepes, Nicole M. Kettner, Tuyen Bui, Akshara S. Raghavendra, Xiayu Rao, Jing Wang, Aysegul Sahin, Senthil Damodaran, Debasish Tripathy, Kelly K. Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1798.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1798
Published: 15 June 2022
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Journal Articles

Abstract 458: Development and validation of convolutional neural network to identify regions of interest in lumpectomy margins using optical coherence tomography

David Rempel, Andrew Berkeley, Chandandeep Nagi, Vladimir Pekar, Margaret Burns, Beryl Augustine, Alia Nazarullah, Ismail Jatoi, Kelly K. Hunt, Alastair Thompson, Savitri Krishnamurthy
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 458.
DOI: https://doi.org/10.1158/1538-7445.AM2022-458
Published: 15 June 2022
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Journal Articles

Abstract 2592: Aurora kinase is an actionable target in low molecular weight cyclin E induced mammary tumors

Said Akli, Amriti R. Lulla, Francisco R. Saenz, Fuchenchu Wang, Natalie W. Fowlkes, Tuyen Bui, Yan Wang, Sofia Mastoraki, Min Jin Ha, Kelly K. Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2592.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2592
Published: 15 June 2022
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Journal Articles

Abstract 1774: Circulating IL-6, an early biomarker in HR-positive, HER2-negative metastatic breast cancer patients progressing on CDK4/6 inhibitors

Nicole M. Kettner, Tuyen N. Bui, Juliana Navarro-Yepes, T Kris Eckols, Akshara S. Raghavendra, David J. Tweardy, Kelly K. Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1774.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1774
Published: 15 June 2022
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Journal Articles

Abstract 515: Single-cell transcriptomic analysis of HR+/HER2- breast cancer identifies gene signatures that predict outcomes of luminal A and B subtypes

Sofia Mastoraki, Jerome Lin, Xiayu Rao, Sophie R. Liu, Harsh Batra, Maria G. Raso, Edwin R. Parra Cuentas, Akshara S. Raghavendra, Komal S. Rasaputra, Min Yi, Jing Wang, Aysegul Sahin, Debasish Tripathy, Kelly K. Hunt, Nicholas E. Navin, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 515.
DOI: https://doi.org/10.1158/1538-7445.AM2022-515
Published: 15 June 2022
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Journal Articles

Abstract 1348: LMW-E induction and crosstalk with immune cells potentiates local immune responses leading to an immunosuppressive microenvironment at the early stages of breast tumorigenesis in mouse models

Sofia Mastoraki, Amriti R. Lulla, Sarah Schneider, Karen Clise-Dwyer, Morgan M. Green, Natalie W. Fowlkes, Kelly K. Hunt, Stephanie S. Watowich, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1348.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1348
Published: 15 June 2022
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Journal Articles

Abstract 264: Neutrophil elastase (NE) inhibition enhances metastasis free survival by altering regulation of tumor intrinsic cytoskeletal and cellular adhesion pathways in murine breast cancer models

Amriti R. Lulla, Said Akli, Lucas D. Warma, Natalie W. Fowlkes, Kelly K. Hunt, Xiayu Rao, Jing Wang, Stephanie S. Watowich, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 264.
DOI: https://doi.org/10.1158/1538-7445.AM2022-264
Published: 15 June 2022
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Journal Articles

Abstract P1-19-01: Palbociclib plus endocrine therapy significantly enhances overall survival of HR+/HER2- metastatic breast cancer patients compared to endocrine therapy alone - A large institutional study

Akshara Singareeka Raghavendra, Min Jin Ha, Nicole M. Kettner, Senthil Damodaran, Rachel Layman, Kelly K Hunt, Yu Shen, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-19-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P1-19-01
Published: 15 February 2022
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Journal Articles

Abstract P2-05-02: Low molecular weight cyclin E facilitate replication stress tolerance in breast cancer development

Mi Li, Kwang Huei Low, Tuyen Bui, Kelly K Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-05-02.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P2-05-02
Published: 15 February 2022
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Journal Articles

Abstract PS1-17: Comparing survival differences between breast-conserving therapy and mastectomy in patients with early-stage breast cancer undergoing upfront surgery

Min Yi, Mariana Chavez Mac Gregor, Benjamin Smith, Abigail S Caudle, Sarah M DeSnyder, Henry M Kuerer, Kelly K Hunt
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS1-17.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS1-17
Published: 15 February 2021
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Journal Articles

Abstract P2-05-04: Low molecular weight cyclin E facilitates replication stress tolerance in breast cancer development

Mi Li, Kwang Huei Low, Tuyen Bui, Kelly K Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P2-05-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P2-05-04
Published: 15 February 2020
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Journal Articles

Abstract P5-06-09: Comparative analysis of proposed strategies for incorporating biologic factors into breast cancer staging

Olga Kantor, Jiangong Niu, Hui Zhao, Sharon H Giordano, Kelly K Hunt, Tari A King, Elizabeth A Mittendorf, Mariana Chavez-MacGregor
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-06-09.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P5-06-09
Published: 15 February 2020
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Journal Articles

Abstract PD2-05: Differential mechanisms of acquired resistance to abemaciclib versus palbociclib reveal novel therapeutic strategies for CDK4/6 therapy-resistant breast cancers

Juliana Navarro-Yepes, Xian Chen, Tuyen Bui, Nicole M Kettner, Kelly K Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): PD2-05.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-PD2-05
Published: 15 February 2020
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Journal Articles

Abstract P6-03-09: Role of IL-6 in promoting endocrine therapy and palbociclib resistance estrogen receptor positive breast cancer cells

Nicole M Kettner, Tuyen Bui, Xian Chen, Kelly K Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-03-09.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P6-03-09
Published: 15 February 2020
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Journal Articles

Abstract P6-04-12: STAT3 as a therapeutic target in estrogen receptor positive breast cancer patients refractory to CDK4/6 inhibition

Nicole M Kettner, Tuyen Bui, Min Jin Ha, T Kris Eckols, David J Tweardy, Funda Meric-Bernstam, Kelly K Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-04-12.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P6-04-12
Published: 15 February 2020
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Journal Articles

Abstract 323: Combined inhibition of STAT-3 & DNA repair in palbociclib resistant breast cancer

Nicole M. Kettner, Smruthi Vijayaraghavan, Merih Guray Durak, Tuyen Bui, Mehrnoosh Kohansal, Min Jin Ha, Bin Liu, Xiayu Rao, Jing Yang, Min Yi, Jason P. Carey, Xian Chen, T. Kris Eckols, Akshara S. Raghavendra, Nuhad K. Ibrahim, Meghan Karuturi, Stephanie S. Watowich, Aysegul A. Sahin, David J. Tweardy, Kelly K. Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 323.
DOI: https://doi.org/10.1158/1538-7445.AM2019-323
Published: 01 July 2019
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Journal Articles

Abstract CT220: Expansion into multiple institutions for training in the use of the LUM Imaging System for intraoperative detection of residual cancer in the tumor bed of female subjects with breast cancer

Kate Smith, Jorge M. Ferrer, Barbara L. Smith, E. Shelley Hwang, Kelly K. Hunt, Daleela G. Dodge, Stephen E. Karp, Stephanie A. Valente, Irene L. Wapnir, Lynne P. Clark, David R. Carr, Peter D. Beitsch, Donna L. Dyess, Beth-Ann Lesnikoski, Peter W. Blumencranz, Nayana S. Dekhne, Linsey P. Gold, Anees Chagpar, Katherine Kacena, Livia Gjylameti, Felix Geissler
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT220.
DOI: https://doi.org/10.1158/1538-7445.AM2019-CT220
Published: 01 July 2019
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Journal Articles

Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies

Joseph A. Caruso, Mylinh T. Duong, Jason P. W. Carey, Kelly K. Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2018) 78 (19): 5481–5491.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-1235
Published: 01 October 2018
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