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Keith L. Knutson
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Journal Articles

Abstract CT182: Phase I trials of personalized cancer vaccine TG4050 in surgically treated high-risk head and neck squamous cell carcinoma (HNSCC) and relapsing ovarian cancer (OvC) patients

Matthew S. Block, Jean-Pierre Delord, Christian H. Ottensmeier, Christophe Le Tourneau, Ana Lalanne, Olivier Lantz, Keith L. Knutson, Gisèle Lacoste, Annette Tavernaro, Maud Brandely, Nathalie Silvestre, Benoit Grellier, Yoshiko Yamashita, Onoue Kousuke, Naoko Yamagata, Eric Quemeneur, Kaidre Bendjama
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT182.
DOI: https://doi.org/10.1158/1538-7445.AM2022-CT182
Published: 15 June 2022
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Abstract 5627: Functional tertiary lymphoid structure (TLS) and outcome in HER2-positive (HER2+) breast cancer in NCCTG N9831 (Alliance)

Saranya Chumsri, Tracy R. Shachner, Zhuo Li, Nadine Norton, Alvaro Moreno-Aspitia, Gerardo Colon-Otero, Edith A. Perez, E. A. Thompson, Aziza Nassar, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5627.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5627
Published: 15 June 2022
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Journal Articles

Abstract P3-23-01: Antibody responses after SARS-CoV-2 mRNA vaccination in breast cancer patients

Saranya Chumsri, Pooja P. Advani, Tanmayi S Pai, Zhou Li, Marites Acampora, Gina A Reynolds, Alvaro Moreno-Aspitia, Christopher P Marquez, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-23-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-23-01
Published: 15 February 2022
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Journal Articles

Abstract 1484: SCD-1 blockade sensitizes triple negative breast cancer to immune checkpoint inhibition

Sneha Vivekanandhan, Justyna Trynda, Laura A. Marlow, Barath shreeder, James L. Miller, Adam M. Kase, Winston Tan, Keith L. Knutson, John A. Copland
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1484.
DOI: https://doi.org/10.1158/1538-7445.AM2021-1484
Published: 01 July 2021
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Journal Articles

Abstract PS6-02: Spatially defined immune-related proteins and outcome in triple negative breast cancer in the FinXX trial and Mayo Clinic cohort

Saranya Chumsri, Jodi M. Carter, Yaohua Ma, Douglas Hinerfeld, Heather Ann Brauer, Sarah Warren, Torsten O. Nielsen, Karama Asleh, Heikki Joensuu, Edith A. Perez, Roberto A. Leon-Ferre, David W. Hillman, Judy C. Boughey, Minetta C. Liu, James N. Ingle, Krishna R. Kalari, Fergus J. Couch, Keith L. Knutson, Matthew P. Goetz, E. A. Thompson
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS6-02.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS6-02
Published: 15 February 2021
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Journal Articles

Abstract P5-04-09: Deep phenotyping using CyTOF identifies peripheral blood immune signatures associated with clinical outcomes and molecular subtypes in patients with early-stage triple negative breast cancer (TNBC)

Roberto A Leon-Ferre, Kaitlyn McGrath, Jodi M Carter, Krishna R Kalari, Vera J Suman, Richard Weinshilboum, Liewei Wang, Keith L Knutson, Stephen M Ansell, Judy C Boughey, J C Villasboas, Matthew P Goetz
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-04-09.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P5-04-09
Published: 15 February 2020
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Journal Articles

Abstract 1464: Inhibition of p38 MAPK in dendritic cells enhances their antigen presentation and induces Th17 T cell differentiation

Yan Luo, Shreeder Barath, Deborah A. Bahr, Navnita Dutta, Geraldine Raja, Martin J. Cannon, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1464.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1464
Published: 01 July 2019
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Journal Articles

IL10 Release upon PD-1 Blockade Sustains Immunosuppression in Ovarian Cancer

Purushottam Lamichhane, Lavakumar Karyampudi, Barath Shreeder, James Krempski, Deborah Bahr, Joshua Daum, Kimberly R. Kalli, Ellen L. Goode, Matthew S. Block, Martin J. Cannon, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2017) 77 (23): 6667–6678.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-0740
Published: 30 November 2017
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Includes: Supplementary data
Journal Articles

Abstract 1682: Correlation of immune co-stimulatory molecule OX40 and outcome in trastuzumab treated HER2-positive breast cancer patients in the NCCTG-N9831

Saranya Chumsri, Daniel J. Serie, Afshin Mashadi-Hossein, Sarah Warren, Alvaro Moreno-Aspitia, Geraldo Colon-Otero, Keith L. Knutson, Edith A. Perez, E. Aubrey Thompson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1682.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1682
Published: 01 July 2017
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Journal Articles

Improved Survival of HER2+ Breast Cancer Patients Treated with Trastuzumab and Chemotherapy Is Associated with Host Antibody Immunity against the HER2 Intracellular Domain

Keith L. Knutson, Raphael Clynes, Barath Shreeder, Patrick Yeramian, Kathleen P. Kemp, Karla Ballman, Kathleen S. Tenner, Courtney L. Erskine, Nadine Norton, Donald Northfelt, Winston Tan, Carmen Calfa, Mark Pegram, Elizabeth A. Mittendorf, Edith A. Perez
Journal: Cancer Research
Cancer Res (2016) 76 (13): 3702–3710.
DOI: https://doi.org/10.1158/0008-5472.CAN-15-3091
Published: 30 June 2016
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Journal Articles

PD-1 Blunts the Function of Ovarian Tumor–Infiltrating Dendritic Cells by Inactivating NF-κB

Lavakumar Karyampudi, Purushottam Lamichhane, James Krempski, Kimberly R. Kalli, Marshall D. Behrens, Doris M. Vargas, Lynn C. Hartmann, Jo Marie T. Janco, Haidong Dong, Karen E. Hedin, Allan B. Dietz, Ellen L. Goode, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2016) 76 (2): 239–250.
DOI: https://doi.org/10.1158/0008-5472.CAN-15-0748
Published: 14 January 2016
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Includes: Supplementary data
Journal Articles

Abstract 2364: CD68+ immune cells show different infiltration patterns in tissue samples from women with no clinical breast disease and those who have benign breast disease

Muhammad A. Arshad, Daniel W. Visscher, Tanya L. Hoskin, Rushin D. Brahmbhatt, Alvaro Pena Jimenez, Melody L. Stallings Mann, Erin E. Miller, Linda M. Murphy, Jodi M. Carter, Stacey J. Winham, Keith L. Knutson, Derek C. Radisky, Amy C. Degnim
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2364.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2364
Published: 01 August 2015
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Journal Articles

Oncolytic Measles Virus Expressing the Sodium Iodide Symporter to Treat Drug-Resistant Ovarian Cancer

Evanthia Galanis, Pamela J. Atherton, Matthew J. Maurer, Keith L. Knutson, Sean C. Dowdy, William A. Cliby, Paul Haluska, Jr, Harry J. Long, Ann Oberg, Ileana Aderca, Matthew S. Block, Jamie Bakkum-Gamez, Mark J. Federspiel, Stephen J. Russell, Kimberly R. Kalli, Gary Keeney, Kah Whye Peng, Lynn C. Hartmann
Journal: Cancer Research
Cancer Res (2015) 75 (1): 22–30.
DOI: https://doi.org/10.1158/0008-5472.CAN-14-2533
Published: 04 January 2015
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Journal Articles

Abstract 1873: Plasma heat shock protein 90kDa beta member 1 levels predict both early stage and advanced stage ovarian cancer independently from cancer antigen 125 in patients with an indeterminate adnexal mass

Matthew S. Block, Matthew J. Maurer, Krista Goergen, Kimberly R. Kalli, Courtney L. Erskine, Marshall D. Behrens, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1873.
DOI: https://doi.org/10.1158/1538-7445.AM2014-1873
Published: 01 October 2014
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Journal Articles

Accumulation of Memory Precursor CD8 T Cells in Regressing Tumors following Combination Therapy with Vaccine and Anti-PD-1 Antibody

Lavakumar Karyampudi, Purushottam Lamichhane, Adam D. Scheid, Kimberly R. Kalli, Barath Shreeder, James W. Krempski, Marshall D. Behrens, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2014) 74 (11): 2974–2985.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-2564
Published: 29 May 2014
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Includes: Supplementary data
Journal Articles

Tumor Hypomethylation at 6p21.3 Associates with Longer Time to Recurrence of High-Grade Serous Epithelial Ovarian Cancer

Chen Wang, Mine S. Cicek, Bridget Charbonneau, Kimberly R. Kalli, Sebastian M. Armasu, Melissa C. Larson, Gottfried E. Konecny, Boris Winterhoff, Jian-Bing Fan, Marina Bibikova, Jeremy Chien, Viji Shridhar, Matthew S. Block, Lynn C. Hartmann, Daniel W. Visscher, Julie M. Cunningham, Keith L. Knutson, Brooke L. Fridley, Ellen L. Goode
Journal: Cancer Research
Cancer Res (2014) 74 (11): 3084–3091.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-3198
Published: 29 May 2014
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Journal Articles

Risk of Ovarian Cancer and the NF-κB Pathway: Genetic Association with IL1A and TNFSF10

Bridget Charbonneau, Matthew S. Block, William R. Bamlet, Robert A. Vierkant, Kimberly R. Kalli, Zachary Fogarty, David N. Rider, Thomas A. Sellers, Shelley S. Tworoger, Elizabeth Poole, Harvey A. Risch, Helga B. Salvesen, Lambertus A. Kiemeney, Laura Baglietto, Graham G. Giles, Gianluca Severi, Britton Trabert, Nicolas Wentzensen, Georgia Chenevix-Trench, for AOCS/ACS group, Alice S. Whittemore, Weiva Sieh, Jenny Chang-Claude, Elisa V. Bandera, Irene Orlow, Kathryn Terry, Marc T. Goodman, Pamela J. Thompson, Linda S. Cook, Mary Anne Rossing, Roberta B. Ness, Steven A. Narod, Jolanta Kupryjanczyk, Karen Lu, Ralf Butzow, Thilo Dörk, Tanja Pejovic, Ian Campbell, Nhu D. Le, Clareann H. Bunker, Natalia Bogdanova, Ingo B. Runnebaum, Diana Eccles, James Paul, Anna H. Wu, Simon A. Gayther, Estrid Hogdall, Florian Heitz, Stanley B. Kaye, Beth Y. Karlan, Hoda Anton-Culver, Jacek Gronwald, Claus K. Hogdall, Diether Lambrechts, Peter A. Fasching, Usha Menon, Joellen Schildkraut, Celeste Leigh Pearce, Douglas A. Levine, Susanne Kruger Kjaer, Daniel Cramer, James M. Flanagan, Catherine M. Phelan, Robert Brown, Leon F.A.G. Massuger, Honglin Song, Jennifer A. Doherty, Camilla Krakstad, Dong Liang, Kunle Odunsi, Andrew Berchuck, Allan Jensen, Jan Lubiński, Heli Nevanlinna, Yukie T. Bean, Galina Lurie, Argyrios Ziogas, Christine Walsh, Evelyn Despierre, Louise Brinton, Alexander Hein, Anja Rudolph, Agnieszka Dansonka-Mieszkowska, Sara H. Olson, Philipp Harter, Jonathan Tyrer, Allison F. Vitonis, Angela Brooks-Wilson, Katja K. Aben, Malcolm C. Pike, Susan J. Ramus, Elisabeth Wik, Cezary Cybulski, Jie Lin, Lara Sucheston, Robert Edwards, Valerie McGuire, Jenny Lester, Andreas du Bois, Lene Lundvall, Shan Wang-Gohrke, Lukasz M. Szafron, Sandrina Lambrechts, Hannah Yang, Matthias W. Beckmann, Liisa M. Pelttari, Anne M. Van Altena, David van den Berg, Mari K. Halle, Aleksandra Gentry-Maharaj, Ira Schwaab, Urmila Chandran, Janusz Menkiszak, Arif B. Ekici, Lynne R. Wilkens, Arto Leminen, Francesmary Modugno, Grace Friel, Joseph H. Rothstein, Ignace Vergote, Montserrat Garcia-Closas, Michelle A.T. Hildebrandt, Piotr Sobiczewski, Linda E. Kelemen, Paul D.P. Pharoah, Kirsten Moysich, Keith L. Knutson, Julie M. Cunningham, Brooke L. Fridley, Ellen L. Goode
Journal: Cancer Research
Cancer Res (2014) 74 (3): 852–861.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-1051
Published: 02 February 2014
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Includes: Supplementary data
Journal Articles

Abstract 3476: Higher plasma levels of heparan sulfate are associated with improved survival of patients with advanced ovarian cancer.

Matthew S. Block, Matthew J. Maurer, Krista M. Goergen, Courtney L. Erskine, Marshall D. Behrens, Kimberly R. Kalli, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3476.
DOI: https://doi.org/10.1158/1538-7445.AM2013-3476
Published: 15 April 2013
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Abstract 1382: Increased expression of placental growth factor is linked with shortened survival of patients with advanced ovarian cancer

Matthew S. Block, Matthew J. Maurer, Priya Ramar, Marshall D. Behrens, Courtney L. Erskine, Kimberly R. Kalli, Lynn C. Hartmann, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1382.
DOI: https://doi.org/10.1158/1538-7445.AM2012-1382
Published: 15 April 2012
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TGFβ/TNFα-Mediated Epithelial–Mesenchymal Transition Generates Breast Cancer Stem Cells with a Claudin-Low Phenotype

Michael K. Asiedu, James N. Ingle, Marshall D. Behrens, Derek C. Radisky, Keith L. Knutson
Journal: Cancer Research
Cancer Res (2011) 71 (13): 4707–4719.
DOI: https://doi.org/10.1158/0008-5472.CAN-10-4554
Published: 30 June 2011
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