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Keith Dredge
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Journal Articles

Abstract 367: The heparan sulfate mimetic PG545 inhibits tumor growth in both male and female mouse model of pancreatic ductal adenocarcinoma (PDAC) with sex difference in the effect on cachexia

Xiaoling Zhong, Keith Dredge, John M. Chirgwin, Michael G. House, Harikrishna Nakshatri, Teresa A. Zimmers
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 367.
https://doi.org/10.1158/1538-7445.AM2023-367
Published: 04 April 2023
View article titled, Abstract 367: The heparan sulfate mimetic PG545 inhibits tumor growth in both male and female mouse model of pancreatic ductal adenocarcinoma (PDAC) with sex difference in the effect on cachexia
Journal Articles

Abstract 1135: Loss of HSulf-1 promotes defective autophagy and increased lipid droplet biogenesis in ovarian cancer

Debarshi Roy, Susmita Mondal, Ashwani Khurana, Xiaoping He, Edward Hammond, Keith Dredge, Viji Shridhar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1135.
https://doi.org/10.1158/1538-7445.AM2015-1135
Published: 01 August 2015
View article titled, Abstract 1135: Loss of HSulf-1 promotes defective autophagy and increased lipid droplet biogenesis in ovarian cancer
Journal Articles

The Increasing Urgency for Standards in Basic Biologic Research Published Recently in Cancer Research—Letter

Keith Dredge
Journal: Cancer Research
Cancer Res (2014) 74 (24): 7599.
https://doi.org/10.1158/0008-5472.CAN-14-2313
Published: 14 December 2014
View article titled, The Increasing Urgency for Standards in Basic Biologic Research Published Recently in <em>Cancer Research—</em>Letter
Open the PDF for The Increasing Urgency for Standards in Basic Biologic Research Published Recently in <em>Cancer Research—</em>Letter in another window
Journal Articles

Abstract 3695: The utility of plasma vascular endothelial growth factor and heparanase as pharmacodynamic markers following treatment with PG545, a heparan sulfate mimetic: preliminary evidence from preclinical and clinical settings

Keith Dredge, Edward Hammond, Boris Winterhoff, Shailendra Giri, Attila Teoman, Darryn Bampton, Michael Millward, Viji Shridhar
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3695.
https://doi.org/10.1158/1538-7445.AM2014-3695
Published: 01 October 2014
View article titled, Abstract 3695: The utility of plasma vascular endothelial growth factor and heparanase as pharmacodynamic markers following treatment with PG545, a heparan sulfate mimetic: preliminary evidence from preclinical and clinical settings
Journal Articles

Abstract 1461: The heparan sulfate mimetic PG545 potently inhibits spontaneous lung metastasis and significantly enhances overall survival in the 4T1 breast carcinoma model

Keith Dredge, Edward Hammond, Paul Handley, Jessica Rowley, Christina Vincent, Ralf Brandt, Ian Bytheway
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1461.
https://doi.org/10.1158/1538-7445.AM2011-1461
Published: 15 April 2011
View article titled, Abstract 1461: The heparan sulfate mimetic PG545 potently inhibits spontaneous lung metastasis and significantly enhances overall survival in the 4T1 breast carcinoma model
Journal Articles

Abstract #LB-205: PG11047, A Polyamine Analog, Induces Potent Antitumor Activity in a Preclinical Model of Non-Small Cell Lung Cancer in Combination with Cisplatin.

Keith Dredge, John Kink, Randolph Johnson, Ian Bytheway, Paul Handley, Laurence Marton
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-205.
Published: 01 May 2009
View article titled, Abstract #LB-205: PG11047, A Polyamine Analog, Induces Potent Antitumor Activity in a Preclinical Model of Non-Small Cell Lung Cancer in Combination with Cisplatin.
Journal Articles

Novel Heparan Sulfate mimetics, the PG500 series, block angiogenesis and prevent tumor growth

Anand Gautam, Keith Dredge, Ligong Liu, Caiping Li, Ken Johnston, Edward Hammond, Norbert Wimmer, Ian Bytheway, Tom Gonda, Vito Ferro
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 362.
Published: 01 May 2008
View article titled, Novel Heparan Sulfate mimetics, the PG500 series, block angiogenesis and prevent tumor growth
Journal Articles

Heparan sulfate mimetics inhibit angiogenesis

Anand Gautam, Ligong Liu, Tomislav Karoli, Cai Ping Li, Ken Johnstone, Edward Hammond, Ian Bytheway, Keith Dredge, Elizabeth Copeman, Kat Davis, Tom Gonda, Vito Ferro
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4656.
Published: 01 May 2007
View article titled, Heparan sulfate mimetics inhibit angiogenesis
Journal Articles

Comparison of anti-angiogenic activities of thalidomide and lenalidomide in vitro

Ling-Hua Zhang, Ling Lu, Lei Wu, Keith Dredge, J Blake Bartlett, Peter H. Schafer, George Muller, Angus Dalgleish
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 415.
Published: 15 April 2006
View article titled, Comparison of anti-angiogenic activities of thalidomide and lenalidomide in vitro
Journal Articles

A Novel Subclass of Thalidomide Analogue with Anti-Solid Tumor Activity in Which Caspase-dependent Apoptosis is Associated with Altered Expression of bcl-2 Family Proteins

J. Blake Marriott, Ian A. Clarke, Anna Czajka, Keith Dredge, Kay Childs, Hon-Wah Man, Peter Schafer, Sowmya Govinda, George W. Muller, David I. Stirling, Angus G. Dalgleish
Journal: Cancer Research
Cancer Res (2003) 63 (3): 593–599.
Published: 01 February 2003
View article titled, A Novel Subclass of Thalidomide Analogue with Anti-Solid Tumor Activity in Which Caspase-dependent Apoptosis is Associated with Altered Expression of bcl-2 Family Proteins
Open the PDF for A Novel Subclass of Thalidomide Analogue with Anti-Solid Tumor Activity in Which Caspase-dependent Apoptosis is Associated with Altered Expression of bcl-2 Family Proteins in another window