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Keith Chan
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Journal Articles

Abstract 1398: Caspase-1 dependent lytic cell death influences intra-tumoral neutrophil-to-lymphocyte ratio that limits chemotherapy efficacy

Stephen (Qi Rong) Wong, Ethan Subel, Kazukuni Hayashi, Hongbo Gao, Fotis Nikolo, Keith Chan
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1398.
https://doi.org/10.1158/1538-7445.AM2025-1398
Published: 21 April 2025
View articletitled, Abstract 1398: Caspase-1 dependent lytic cell death influences intra-tumoral neutrophil-to-lymphocyte ratio that limits chemotherapy efficacy
Journal Articles

Abstract 1359: iNOS inhibition reprograms the tumor microenvironment enhancing antitumor immunity in obesity associated triple negative breast cancer (TNBC)

Ivonne Uzair, Fotis Nikolo, Sean Hynes, Gianmarco Melone, Karina Ortega, Jenying Deng, Wei Qian, Jianying Zhou, Liliana Guzman, Christoforos Thomas, Keith Chan, Jenny Chang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1359.
https://doi.org/10.1158/1538-7445.AM2025-1359
Published: 21 April 2025
View articletitled, Abstract 1359: iNOS inhibition reprograms the tumor microenvironment enhancing antitumor immunity in obesity associated triple negative breast cancer (TNBC)
Journal Articles

Abstract 6545: Targeting NOS2 and the tumor microenvironment in ovarian cancer: Switching the immune system from “cold” to “hot”

Gianmarco Melone, Ivonne Uzair, Mailin Li, Maria Chervo, Karina Ortega, Jenying Deng, Wei Qian, Jianying Zhou, Liliana Guzman, Kristina Zambo, Harika Nagandla, Hong Zhao, Christoforos Thomas, Fotis Nikolo, Keith Chan, Lewis Francis, Jenny Chang, Aireana Phillips, Xen Ping Hoi
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6545.
https://doi.org/10.1158/1538-7445.AM2025-6545
Published: 21 April 2025
View articletitled, Abstract 6545: Targeting NOS2 and the tumor microenvironment in ovarian cancer: Switching the immune system from “cold” to “hot”
Journal Articles

Abstract 1647: Integrative subtype analysis of muscle-invasive bladder cancer reveals subtypes that have different overall survival and respond differently to neoadjuvant chemotherapy

QIANXING MO, Roger Li, Keith Chan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1647.
https://doi.org/10.1158/1538-7445.AM2019-1647
Published: 01 July 2019
View articletitled, Abstract 1647: Integrative subtype analysis of muscle-invasive bladder cancer reveals subtypes that have different overall survival and respond differently to neoadjuvant chemotherapy
Journal Articles

Molecular profiling reveals heterogeneity of active self-renewal pathways in bladder cancer stem cells

Keith Chan, Inigo Espinosa, James Kim, Laurie Ailles, Girmay Zahilay, Harcharan Gill, Joseph Presti, Matt van de Rijn, Phillip Beachy, Linda Shortliffe, Irving Weissman
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4998.
Published: 01 May 2008
View articletitled, Molecular profiling reveals heterogeneity of active self-renewal pathways in bladder cancer stem cells
Journal Articles

Nanofluidic proteomic approach reveals protein levels and post-translational modifications in limiting tumor stem cell material not detectable with nucleic acid techniques

Keith Chan, David Voehringer, Arunashree Bhamidipati, Irving Weissman
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2474.
Published: 01 May 2007
View articletitled, Nanofluidic proteomic approach reveals protein levels and post-translational modifications in limiting tumor stem cell material not detectable with nucleic acid techniques
Journal Articles

Post-translational modification of β-Catenin as a molecular classification marker in colorectal cancer: insight into Wnt signaling in tumor stem cells

Arunashree Bhamidipati, Keith Chan, Daryl Taketa, Uyen Nguyen, David Voehringer, Irving Weissman
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 719.
Published: 01 May 2007
View articletitled, Post-translational modification of β-Catenin as a molecular classification marker in colorectal cancer: insight into Wnt signaling in tumor stem cells
Journal Articles

Constitutive Expression of ErbB-2 in Gallbladder Epithelium Results in Development of Adenocarcinoma

Kaoru Kiguchi, Steve Carbajal, Keith Chan, Linda Beltrán, Lynnsie Ruffino, Jianjun Shen, Takashi Matsumoto, Naoki Yoshimi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2001) 61 (19): 6971–6976.
Published: 01 October 2001
View articletitled, Constitutive Expression of ErbB-2 in Gallbladder Epithelium Results in Development of Adenocarcinoma
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Journal Articles

Pharmacokinetic and Phase I Evaluation of Esorubicin (4′-Deoxydoxorubicin) by Continuous Infusion over Forty-eight Hours in Patients with Leukemia

Willi Kreis, Cheryl Rottach, Daniel R. Budman, Keith Chan, Philip Schulman, Steven L. Allen, Lora Weiselberg, Vincent Vinciguerra
Journal: Cancer Research
Cancer Res (1988) 48 (19): 5580–5584.
Published: 01 October 1988
View articletitled, Pharmacokinetic and Phase I Evaluation of Esorubicin (4′-Deoxydoxorubicin) by Continuous Infusion over Forty-eight Hours in Patients with Leukemia
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Journal Articles

Effect of Tetrahydrouridine on the Clinical Pharmacology of 1-β-d-Arabinofuranosylcytosine When Both Drugs Are Coinfused over Three Hours1

Willi Kreis, Keith Chan, Daniel R. Budman, Phillip Schulman, Steven Allen, Lora Weiselberg, Stuart Lichtman, Vicki Henderson, Jean Freeman, Margaret Deere, Michael Andreeff, Vincent Vinciguerra
Journal: Cancer Research
Cancer Res (1988) 48 (5): 1337–1342.
Published: 01 March 1988
View articletitled, Effect of Tetrahydrouridine on the Clinical Pharmacology of 1-β-d-Arabinofuranosylcytosine When Both Drugs Are Coinfused over Three Hours1
Open the PDF for Effect of Tetrahydrouridine on the Clinical Pharmacology of 1-β-d-Arabinofuranosylcytosine When Both Drugs Are Coinfused over Three Hours1 in another window
Journal Articles

Pharmacokinetics of Low-Dose 1-β-d-Arabinofuranosylcytosine Given by Continuous Intravenous Infusion over Twenty-one Days1

Willi Kreis, Farida Chaudhri, Keith Chan, Steven Allen, Daniel R. Budman, Philip Schulman, Lora Weiselberg, Jean Freeman, Margaret Deere, Vincent Vinciguerra
Journal: Cancer Research
Cancer Res (1985) 45 (12_Part_1): 6498–6501.
Published: 01 December 1985
View articletitled, Pharmacokinetics of Low-Dose 1-β-d-Arabinofuranosylcytosine Given by Continuous Intravenous Infusion over Twenty-one Days1
Open the PDF for Pharmacokinetics of Low-Dose 1-β-d-Arabinofuranosylcytosine Given by Continuous Intravenous Infusion over Twenty-one Days1 in another window