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Abstract 4662: Epigenetic conversion on p53 pathway in human cancer: The clinical potential of p53 mutation status as a predictive biomarker for drug sensitivity by epigenetic treatment.

Keishi Yamashita, Mina Waraya, Hiroshi Katoh, Akira Ooki, Hiroshi Kawamata, Kazunori Nakamura, Hiroshi Nishimiya, Akira Ema, David Sidransky, Masahiko Watanabe

Cancer Res (2013) 73 (8_Supplement): 4662.

https://doi.org/10.1158/1538-7445.AM2013-4662

Published: 15 April 2013

View articletitled, Abstract 4662: Epigenetic conversion on p53 pathway in human cancer: The clinical potential of p53 mutation status as a predictive biomarker for drug sensitivity by epigenetic treatment.

Journal Articles

Abstract 963: Epigenetic silencing of cancer-specific methylation may converge on therapeutic targets on human cancers

Keishi Yamashita, Myoung Sook Kim, Akira Ooki, Hiroshi Kato, Mina Waraya, Hiroshi Kawamata, Masahiko Watanabe, David Sidransky

Cancer Res (2012) 72 (8_Supplement): 963.

https://doi.org/10.1158/1538-7445.AM2012-963

Published: 15 April 2012

View articletitled, Abstract 963: Epigenetic silencing of cancer-specific methylation may converge on therapeutic targets on human cancers

Journal Articles

Abstract LB-341: Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers

Mariana Brait, Shizhang Ling, Jatin Nagpal, Xiaofei Chang, Hannah Park, Juna Lee, Jun Okamura, Keishi Yamashita, David Sidransky, Myoung Sook Kim

Cancer Res (2012) 72 (8_Supplement): LB-341.

https://doi.org/10.1158/1538-7445.AM2012-LB-341

Published: 15 April 2012

View articletitled, Abstract LB-341: Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers

Journal Articles

Abstract 4155: Comprehensive glucan profile exploration of mutated K-ras knockdown in colorectal cancer

Hiroshi Kawamata, Keishi Yamashita, Atsushi Kuno, Seiji Shirasawa, Hisashi Narimatsu, Masahiko Watanabe

Cancer Res (2012) 72 (8_Supplement): 4155.

https://doi.org/10.1158/1538-7445.AM2012-4155

Published: 15 April 2012

View articletitled, Abstract 4155: Comprehensive glucan profile exploration of mutated K-ras knockdown in colorectal cancer

Journal Articles

Abstract 1302: Delayed elimination of SN-38 and prolonged neutropenia in cancer patients with severe renal failure requiring dialysis who receive irinotecan

Ken-Ichi Fujita, Yu Sunakawa, Keisuke Miwa, Yuko Akiyama, Minako Sugiyama, Kaori Kawara, Hiroo Ishida, Keishi Yamashita, Keiko Mizuno, Shigehira Saji, Wataru Ichikawa, Wataru Yamamoto, Fumio Nagashima, Toshimichi Miya, Masaru Narabayashi, Yuichi Ando, Takashi Hirose, Yasutsuna Sasaki

Cancer Res (2011) 71 (8_Supplement): 1302.

https://doi.org/10.1158/1538-7445.AM2011-1302

Published: 15 April 2011

View articletitled, Abstract 1302: Delayed elimination of SN-38 and prolonged neutropenia in cancer patients with severe renal failure requiring dialysis who receive irinotecan

Journal Articles

Abstract 180: Potential utility of Reprimo methylation as a sensitizer to anticancer treatment in gastric cancer

Ooki Akira, Keishi Yamashita, Masahiko Watanabe

Cancer Res (2010) 70 (8_Supplement): 180.

https://doi.org/10.1158/1538-7445.AM10-180

Published: 15 April 2010

View articletitled, Abstract 180: Potential utility of Reprimo methylation as a sensitizer to anticancer treatment in gastric cancer

Journal Articles

Abstract 4947: Homeobox gene HOPX is epigenetically silenced cancer-specifically in colorectal cancer and predicts poor prognosis in stage III colorectal cancer

Hiroshi Katoh, Keishi Yamashita, Akira Ooki, David Sidransky, Masahiko Watanabe

Cancer Res (2010) 70 (8_Supplement): 4947.

https://doi.org/10.1158/1538-7445.AM10-4947

Published: 15 April 2010

View articletitled, Abstract 4947: Homeobox gene HOPX is epigenetically silenced cancer-specifically in colorectal cancer and predicts poor prognosis in stage III colorectal cancer

Journal Articles

Abstract 5067: Neurofilament heavy polypeptide regulates the Akt-β-catenin pathway in human esophageal squamous cell carcinoma

Myoung Sook Kim, Xiaofei Chang, Cynthia LeBron, Jatin K. Nagpal, Juna Lee, Yiping Huang, Keishi Yamashita, Barry Trink, Edward A. Ratovitski, David Sidransky

Cancer Res (2010) 70 (8_Supplement): 5067.

https://doi.org/10.1158/1538-7445.AM10-5067

Published: 15 April 2010

View articletitled, Abstract 5067: Neurofilament heavy polypeptide regulates the Akt-β-catenin pathway in human esophageal squamous cell carcinoma

Journal Articles

Abstract 4671: Tumor Suppressive Role of HOP (homeobox only protein) Gene in Gastric Cancer

Keishi Yamashita, Akira Ooki, Hiroshi Katoh, David Sidransky, Masahiko Watanabe

Cancer Res (2010) 70 (8_Supplement): 4671.

https://doi.org/10.1158/1538-7445.AM10-4671

Published: 15 April 2010

View articletitled, Abstract 4671: Tumor Suppressive Role of HOP (homeobox only protein) Gene in Gastric Cancer

Journal Articles

Abstract #2754: Phosphatase of regenerating liver-3 as prominent factor for lymph node metastasis downstream of EGFR pathway in esophageal squamous cell carcinoma

Ooki Akira, Keishi Yamashita, Masahiko Watanabe

Cancer Res (2009) 69 (9_Supplement): 2754.

Published: 01 May 2009

View articletitled, Abstract #2754: Phosphatase of regenerating liver-3 as prominent factor for lymph node metastasis downstream of EGFR pathway in esophageal squamous cell carcinoma

Journal Articles

Abstract #5160: Oncostatin M receptor \#946; - is epigenetically inactivated in human colon cancer

Myoung Kim, Xiaoli Zhong, Joost Louwagie, Beatriz Carvalho, Jochim Terhaar sive Droste, Keishi Yamashita, Gerrit Meijer, David Sidransky

Cancer Res (2009) 69 (9_Supplement): 5160.

Published: 01 May 2009

View articletitled, Abstract #5160: Oncostatin M receptor \#946; - is epigenetically inactivated in human colon cancer

Journal Articles

Abstract #5431: Pharmacokinetics of S-1 in elderly Japanese patients with cancer

Cancer Res (2009) 69 (9_Supplement): 5431.

Published: 01 May 2009

View articletitled, Abstract #5431: Pharmacokinetics of S-1 in elderly Japanese patients with cancer

Journal Articles

Abstract #1336: Promoter DNA methylation of HOP (homeobox only protein) identified by pharmacological unmasking microarray has a great potential of clinical utility as an aggressive marker in gastric cancer

Keishi Yamashita, Akira Ooki, Masaki Mori, Myoung Sook Kim, David Sidransky, Masahiko Watanabe

Cancer Res (2009) 69 (9_Supplement): 1336.

Published: 01 May 2009

View articletitled, Abstract #1336: Promoter DNA methylation of HOP (homeobox only protein) identified by pharmacological unmasking microarray has a great potential of clinical utility as an aggressive marker in gastric cancer

Journal Articles

Aberrant promoter methylation of B4GALT1 and OSMR in tissue and fecal DNA from patients with colon cancer.

Myoung Kim, Joost Louwagie, Beatriz Carvalho, Jochim Droste, Junwei Liu, Kimberly askie Ostrow, Hannah Park, Keishi Yamashita, Gerrit Meijer, Wim Criekinge, David Sidransky

Cancer Res (2008) 68 (9_Supplement): 2634.

Published: 01 May 2008

View articletitled, Aberrant promoter methylation of B4GALT1 and OSMR in tissue and fecal DNA from patients with colon cancer.

Journal Articles

Association of ABCC2 genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with FOLFIRI

Ken-ichi Fujita, Fumio Nagashima, Wataru Yamamoto, Hisashi Endo, Yu Sunakawa, Keishi Yamashita, Hiroo Ishida, Keiko Mizuno, Munemichi Matsunaga, Kazuhiro Araki, Ryuhei Tanaka, Wataru Ichikawa, Toshimichi Miya, Masaru Narabayashi, Yuko Akiyama, Kaori Kawara, Yuichi Ando, Yasutsuna Sasaki

Cancer Res (2008) 68 (9_Supplement): 4783.

Published: 01 May 2008

View articletitled, Association of ABCC2 genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with FOLFIRI

Journal Articles

K-ras mutation reflects the definite pathways associated with patient prognosis in young age colon cancer

Keishi Yamashita, Hiroshi Katoh, Wataru Onozato, Masahiko Watanabe

Cancer Res (2008) 68 (9_Supplement): 3880.

Published: 01 May 2008

View articletitled, K-ras mutation reflects the definite pathways associated with patient prognosis in young age colon cancer

Journal Articles

A phase I/II study and pharmacokinetic study of irinotecan in combination with 5-FU/leucovorine (FOLFIRI) in Japanese patients with metastatic colorectal cancer and the role of UGT1A1 polymorphisms

Fumio Nagashima, Ken-ichi Fujita, Wataru Yamamoto, Hisashi Endo, Wataru Ichikawa, Keiko Mizuno, Yu Sunakawa, Keishi Yamashita, Hiroo Ishida, Munemichi Matsunaga, Hiroshi Ito, Kazuhiro Araki, Yuko Akiyama, Kaori Kawara, Ryuhei Tanaka, Toshimichi Miya, Masaru Narabayashi, Yuichi Ando, Yasutsuna Sasaki

Cancer Res (2008) 68 (9_Supplement): 223.

Published: 01 May 2008

View articletitled, A phase I/II study and pharmacokinetic study of irinotecan in combination with 5-FU/leucovorine (FOLFIRI) in Japanese patients with metastatic colorectal cancer and the role of UGT1A1 polymorphisms

Journal Articles

Aberrant hypermethylation in the dfna5 gene promoter increases risk of lymph node metastasis in human breast cancer

Myoung Sook Kim, Cynthia Lebron, Jatin Nagpal, Young Chae, Xiaofei Chang, Yiping Huang, Keishi Yamashita, Barry Trink, Edward Ratovitski, David Sidransky

Cancer Res (2008) 68 (9_Supplement): 2631.

Published: 01 May 2008

View articletitled, Aberrant hypermethylation in the dfna5 gene promoter increases risk of lymph node metastasis in human breast cancer

Journal Articles

Genome-Wide Promoter Analysis Uncovers Portions of the Cancer Methylome

Cancer Res (2008) 68 (8): 2661–2670.

https://doi.org/10.1158/0008-5472.CAN-07-5913

Published: 15 April 2008

View articletitled, Genome-Wide Promoter Analysis Uncovers Portions of the Cancer Methylome

Includes: Supplementary data

Journal Articles

NMDA receptor 2B promoter methylation predicts poor prognosis in esophageal squamous cell carcinoma

Myoung Kim, Keishi Yamashita, Xiaofei Chang, Young Chae, Marianna Zahurak, Guojun Wu, David Sidransky

Cancer Res (2007) 67 (9_Supplement): 1136.

Published: 01 May 2007

View articletitled, NMDA receptor 2B promoter methylation predicts poor prognosis in esophageal squamous cell carcinoma

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Abstract 4662: Epigenetic conversion on p53 pathway in human cancer: The clinical potential of p53 mutation status as a predictive biomarker for drug sensitivity by epigenetic treatment.

Abstract 963: Epigenetic silencing of cancer-specific methylation may converge on therapeutic targets on human cancers

Abstract LB-341: Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers

Abstract 4155: Comprehensive glucan profile exploration of mutated K-ras knockdown in colorectal cancer

Abstract 1302: Delayed elimination of SN-38 and prolonged neutropenia in cancer patients with severe renal failure requiring dialysis who receive irinotecan

Abstract 180: Potential utility of Reprimo methylation as a sensitizer to anticancer treatment in gastric cancer

Abstract 4947: Homeobox gene HOPX is epigenetically silenced cancer-specifically in colorectal cancer and predicts poor prognosis in stage III colorectal cancer

Abstract 5067: Neurofilament heavy polypeptide regulates the Akt-β-catenin pathway in human esophageal squamous cell carcinoma

Abstract 4671: Tumor Suppressive Role of HOP (homeobox only protein) Gene in Gastric Cancer

Abstract #2754: Phosphatase of regenerating liver-3 as prominent factor for lymph node metastasis downstream of EGFR pathway in esophageal squamous cell carcinoma

Abstract #5160: Oncostatin M receptor \#946; - is epigenetically inactivated in human colon cancer

Abstract #5431: Pharmacokinetics of S-1 in elderly Japanese patients with cancer

Abstract #1336: Promoter DNA methylation of HOP (homeobox only protein) identified by pharmacological unmasking microarray has a great potential of clinical utility as an aggressive marker in gastric cancer

Aberrant promoter methylation of B4GALT1 and OSMR in tissue and fecal DNA from patients with colon cancer.

Association of ABCC2 genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with FOLFIRI

K-ras mutation reflects the definite pathways associated with patient prognosis in young age colon cancer

A phase I/II study and pharmacokinetic study of irinotecan in combination with 5-FU/leucovorine (FOLFIRI) in Japanese patients with metastatic colorectal cancer and the role of UGT1A1 polymorphisms

Aberrant hypermethylation in the dfna5 gene promoter increases risk of lymph node metastasis in human breast cancer

Genome-Wide Promoter Analysis Uncovers Portions of the Cancer Methylome

NMDA receptor 2B promoter methylation predicts poor prognosis in esophageal squamous cell carcinoma

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