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Keiichi I. Nakayama
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Journal Articles

Ablation of p57+ Quiescent Cancer Stem Cells Suppresses Recurrence after Chemotherapy of Intestinal Tumors

Takeru Oka, Tsunaki Higa, Osamu Sugahara, Daisuke Koga, Shogo Nakayama, Keiichi I. Nakayama
Journal: Cancer Research
Cancer Res (2023) 83 (9): 1393–1409.
https://doi.org/10.1158/0008-5472.CAN-22-2578
Published: 02 May 2023
View article titled, Ablation of p57<sup>+</sup> Quiescent Cancer Stem Cells Suppresses Recurrence after Chemotherapy of Intestinal Tumors
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Includes: Supplementary data
Journal Articles

Loss of Fbxw7 Impairs Development of and Induces Heterogeneous Tumor Formation in the Mouse Mammary Gland

Ichiro Onoyama, Shogo Nakayama, Hideyuki Shimizu, Keiichi I. Nakayama
Journal: Cancer Research
Cancer Res (2020) 80 (24): 5515–5530.
https://doi.org/10.1158/0008-5472.CAN-20-0271
Published: 15 December 2020
View article titled, Loss of Fbxw7 Impairs Development of and Induces Heterogeneous Tumor Formation in the Mouse Mammary Gland
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Includes: Supplementary data
Journal Articles

Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer

Eri Sakai, Mizuho Nakayama, Hiroko Oshima, Yuta Kouyama, Atsushi Niida, Satoshi Fujii, Atsushi Ochiai, Keiichi I. Nakayama, Koshi Mimori, Yutaka Suzuki, Chang Pyo Hong, Chan-Young Ock, Seong-Jin Kim, Masanobu Oshima
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (5): 1334–1346.
https://doi.org/10.1158/0008-5472.CAN-17-3303
Published: 28 February 2018
View article titled, Combined Mutation of <em>Apc, Kras</em>, and <em>Tgfbr2</em> Effectively Drives Metastasis of Intestinal Cancer
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Includes: Supplementary data
Journal Articles

Abstract 90: K63-linked JARID1B ubiquitination by TRAF6 contributes to aberrant elevation of JARID1B in prostate cancer

Wenfu Lu, Shenji Liu, Bo Li, Yingqiu Xie, Christine Adhiambo, Qing Yang, Billy R. Ballard, Keiichi I. Nakayama, Robert J. Matusik, Zhenbang Chen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 90.
https://doi.org/10.1158/1538-7445.AM2015-90
Published: 01 August 2015
View article titled, Abstract 90: K63-linked JARID1B ubiquitination by TRAF6 contributes to aberrant elevation of JARID1B in prostate cancer
Journal Articles

p53-Altered FBXW7 Expression Determines Poor Prognosis in Gastric Cancer Cases

Takehiko Yokobori, Koshi Mimori, Masaaki Iwatsuki, Hideshi Ishii, Ichiro Onoyama, Takeo Fukagawa, Hiroyuki Kuwano, Keiichi I. Nakayama, Masaki Mori
Journal: Cancer Research
Cancer Res (2009) 69 (9): 3788–3794.
https://doi.org/10.1158/0008-5472.CAN-08-2846
Published: 30 April 2009
View article titled, <em>p53</em>-Altered <em>FBXW7</em> Expression Determines Poor Prognosis in Gastric Cancer Cases
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Includes: Supplementary data
Journal Articles

Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteolytic Release of Soluble TRAIL from Tumor Cell Surface

Tomoyo Kawakubo, Kuniaki Okamoto, Jun-ichi Iwata, Masashi Shin, Yoshiko Okamoto, Atsushi Yasukochi, Keiichi I. Nakayama, Tomoko Kadowaki, Takayuki Tsukuba, Kenji Yamamoto
Journal: Cancer Research
Cancer Res (2007) 67 (22): 10869–10878.
https://doi.org/10.1158/0008-5472.CAN-07-2048
Published: 15 November 2007
View article titled, Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteolytic Release of Soluble TRAIL from Tumor Cell Surface
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Includes: Supplementary data
Journal Articles

Up-regulation of GPR48 Induced by Down-regulation of p27Kip1 Enhances Carcinoma Cell Invasiveness and Metastasis

Yun Gao, Kyoko Kitagawa, Yoshihiro Hiramatsu, Hirotoshi Kikuchi, Tomoyasu Isobe, Mai Shimada, Chiharu Uchida, Takayuki Hattori, Toshiaki Oda, Keiko Nakayama, Keiichi I. Nakayama, Tatsuo Tanaka, Hiroyuki Konno, Masatoshi Kitagawa
Journal: Cancer Research
Cancer Res (2006) 66 (24): 11623–11631.
https://doi.org/10.1158/0008-5472.CAN-06-2629
Published: 18 December 2006
View article titled, Up-regulation of GPR48 Induced by Down-regulation of p27<sup><em>Kip1</em></sup> Enhances Carcinoma Cell Invasiveness and Metastasis
Open the PDF for Up-regulation of GPR48 Induced by Down-regulation of p27<sup><em>Kip1</em></sup> Enhances Carcinoma Cell Invasiveness and Metastasis in another window
Includes: Supplementary data
Journal Articles

Degradation of Tob1 Mediated by SCFSkp2-Dependent Ubiquitination

Yoshihiro Hiramatsu, Kyoko Kitagawa, Toru Suzuki, Chiharu Uchida, Takayuki Hattori, Hirotoshi Kikuchi, Toshiaki Oda, Shigetsugu Hatakeyama, Keiichi I. Nakayama, Tadashi Yamamoto, Hiroyuki Konno, Masatoshi Kitagawa
Journal: Cancer Research
Cancer Res (2006) 66 (17): 8477–8483.
https://doi.org/10.1158/0008-5472.CAN-06-1603
Published: 01 September 2006
View article titled, Degradation of Tob1 Mediated by SCF<sup>Skp2</sup>-Dependent Ubiquitination
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Includes: Supplementary data
Journal Articles

Suppression of Centrosome Amplification after DNA Damage Depends on p27 Accumulation

Eiji Sugihara, Masayuki Kanai, Soichiro Saito, Takayuki Nitta, Hideo Toyoshima, Keiko Nakayama, Keiichi I. Nakayama, Kenji Fukasawa, Manfred Schwab, Hideyuki Saya, Masanao Miwa
Journal: Cancer Research
Cancer Res (2006) 66 (8): 4020–4029.
https://doi.org/10.1158/0008-5472.CAN-05-3250
Published: 17 April 2006
View article titled, Suppression of Centrosome Amplification after DNA Damage Depends on p27 Accumulation
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Journal Articles

Targeted Destruction of c-Myc by an Engineered Ubiquitin Ligase Suppresses Cell Transformation and Tumor Formation

Shigetsugu Hatakeyama, Masashi Watanabe, Yo Fujii, Keiichi I. Nakayama
Journal: Cancer Research
Cancer Res (2005) 65 (17): 7874–7879.
https://doi.org/10.1158/0008-5472.CAN-05-1581
Published: 01 September 2005
View article titled, Targeted Destruction of c-Myc by an Engineered Ubiquitin Ligase Suppresses Cell Transformation and Tumor Formation
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Journal Articles

Skp2 is a downstream target of p107

Genevieve Rodier, Constantin Makris, Philippe Coulombe, Keiko Nakayama, Keiichi I. Nakayama, Sylvain Meloche
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 910.
Published: 01 April 2004
View article titled, Skp2 is a downstream target of p107
Journal Articles

Cell Cycle-dependent Regulation of the Skp2 Promoter by GA-binding Protein

Hiroyuki Imaki, Keiko Nakayama, Sophie Delehouzee, Hiroshi Handa, Masatoshi Kitagawa, Takumi Kamura, Keiichi I. Nakayama
Journal: Cancer Research
Cancer Res (2003) 63 (15): 4607–4613.
Published: 07 August 2003
View article titled, Cell Cycle-dependent Regulation of the <em>Skp2</em> Promoter by GA-binding Protein
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