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Kazuyoshi Yanagihara
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Journal Articles

Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion

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Masamitsu Tanaka, Sei Kuriyama, Go Itoh, Daichi Maeda, Akiteru Goto, Yutaro Tamiya, Kazuyoshi Yanagihara, Masakazu Yashiro, Namiko Aiba
Journal: Cancer Research
Cancer Res (2017) 77 (3): 684–695.
https://doi.org/10.1158/0008-5472.CAN-16-0964
Published: 31 January 2017
View articletitled, Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion
Open the PDF for Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion in another window
Includes: Supplementary data
Journal Articles

Agr2 Mediates Paracrine Effects on Stromal Fibroblasts That Promote Invasion by Gastric Signet-Ring Carcinoma Cells

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Tadahiro Tsuji, Rika Satoyoshi, Namiko Aiba, Takanori Kubo, Kazuyoshi Yanagihara, Daichi Maeda, Akiteru Goto, Kazuo Ishikawa, Masakazu Yashiro, Masamitsu Tanaka
Journal: Cancer Research
Cancer Res (2015) 75 (2): 356–366.
https://doi.org/10.1158/0008-5472.CAN-14-1693
Published: 14 January 2015
View articletitled, Agr2 Mediates Paracrine Effects on Stromal Fibroblasts That Promote Invasion by Gastric Signet-Ring Carcinoma Cells
Open the PDF for Agr2 Mediates Paracrine Effects on Stromal Fibroblasts That Promote Invasion by Gastric Signet-Ring Carcinoma Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 3601: Stromal fibroblasts mediate extracellular matrix remodeling and invasion of scirrhous gastric carcinoma cells

Free
Hideki Yamaguchi, Kazuyoshi Yanagihara, Masakazu Yashiro, Ryuichi Sakai
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3601.
https://doi.org/10.1158/1538-7445.AM2014-3601
Published: 01 October 2014
View articletitled, Abstract 3601: Stromal fibroblasts mediate extracellular matrix remodeling and invasion of scirrhous gastric carcinoma cells
Journal Articles

Abstract 2096: HIF-1α is a crucial factor in the development of peritoneal dissemination via natural metastatic routes in scirrhous gastric cancer

Free
Shuusuke Miyake, Yoshihiko Kitajima, Jun Nakamura, Keita Kai, Kazuyoshi Yanagihara, Tomokazu Tanaka, Masatsugu Hiraki, Kohji Miyazaki, Hirokazu Noshiro
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2096.
https://doi.org/10.1158/1538-7445.AM2014-2096
Published: 01 October 2014
View articletitled, Abstract 2096: HIF-1α is a crucial factor in the development of peritoneal dissemination via natural metastatic routes in scirrhous gastric cancer
Journal Articles

Abstract 4655: In vitro tyrosine kinase activity profiling to identify molecular targets and predictive biomarkers in gastric cancer cell lines.

Free
Yasuhiro Koh, Masakuni Serizawa, Rik de Wijn, Riet Hilhorst, Takako Nakajima, Hirofumi Yasui, Kazuyoshi Yanagihara, Martijn Dankers, Rob Ruijtenbeek, Narikazu Boku
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4655.
https://doi.org/10.1158/1538-7445.AM2013-4655
Published: 15 April 2013
View articletitled, Abstract 4655: In vitro tyrosine kinase activity profiling to identify molecular targets and predictive biomarkers in gastric cancer cell lines.
Journal Articles

Abstract 412: SEC11A contributes to malignant progression through promotion of EGF and TGF-α secretion in gastric cancer.

Free
Naohide Oue, Tetsutaro Hayashi, Reiko Ito, Akiko Nagatsuma, Kazuhiro Sentani, Naoya Sakamoto, Katsuhiro Anami, Naohiro Uraoka, Yutaka Naito, Kazuyoshi Yanagihara, Atsushi Ochiai, Hiroki Sasaki, Wataru Yasui
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 412.
https://doi.org/10.1158/1538-7445.AM2013-412
Published: 15 April 2013
View articletitled, Abstract 412: SEC11A contributes to malignant progression through promotion of EGF and TGF-α secretion in gastric cancer.
Journal Articles

Abstract 1925: ZDHHC14, a potential regulator in peritoneal dissemination of scirrhous type gastric cancer, identified by CAST method.

Free
Htoo Zarni Oo, Naoya Sakamoto, Naohiro Uraoka, Katsuhiro Anami, Kazuhiro Sentani, Naohide Oue, Kazuyoshi Yanagihara, Wataru Yasui
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1925.
https://doi.org/10.1158/1538-7445.AM2013-1925
Published: 15 April 2013
View articletitled, Abstract 1925: ZDHHC14, a potential regulator in peritoneal dissemination of scirrhous type gastric cancer, identified by CAST method.
Journal Articles

Abstract 47: Cancer-associated fibroblasts mediate extracellular matrix remodeling and three-dimensional invasion of scirrhous gastric carcinoma cells

Free
Hideki Yamaguchi, Kazuyoshi Yanagihara, Masakazu Yashiro, Ryuichi Sakai
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 47.
https://doi.org/10.1158/1538-7445.AM2012-47
Published: 15 April 2012
View articletitled, Abstract 47: Cancer-associated fibroblasts mediate extracellular matrix remodeling and three-dimensional invasion of scirrhous gastric carcinoma cells
Journal Articles

Abstract 5: Frequency of FGFR2 gene amplification in gastric cancer

Free
Kazuko Matsumoto, Tokuzo Arao, Tetsuya Hamaguchi, Yasuhiro Shimada, Ken Kato, Ichiro Oda, Hirokazu Taniguchi, Fumiaki Koizumi, Kazuyoshi Yanagihara, Hiroki Sasaki, Yasuhide Yamada, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5.
https://doi.org/10.1158/1538-7445.AM2012-5
Published: 15 April 2012
View articletitled, Abstract 5: Frequency of FGFR2 gene amplification in gastric cancer
Journal Articles

Abstract 3061: Somatic mutation profiling to tumor samples using OncoCarta Panel

Free
Kazuyuki Furuta, Tokuzo Arao, Kazuyoshi Yanagihara, Masaru Sekijima, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3061.
https://doi.org/10.1158/1538-7445.AM2011-3061
Published: 15 April 2011
View articletitled, Abstract 3061: Somatic mutation profiling to tumor samples using OncoCarta Panel
Journal Articles

Abstract 4468: In vitro evaluation of multi-targeted kinase inhibitors in scirrhous gastric cancer cell lines by tyrosine kinase activity profiling

Free
Yasuhiro Koh, Masakuni Serizawa, Rik de Wijn, Riet Hilhorst, Takako Nakajima, Hirofumi Yasui, Kazuyoshi Yanagihara, Martijn Dankers, Rob Ruijtenbeek, Narikazu Boku
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4468.
https://doi.org/10.1158/1538-7445.AM2011-4468
Published: 15 April 2011
View articletitled, Abstract 4468: In vitro evaluation of multi-targeted kinase inhibitors in scirrhous gastric cancer cell lines by tyrosine kinase activity profiling
Journal Articles

The Metastasis-Associated microRNA miR-516a-3p Is a Novel Therapeutic Target for Inhibiting Peritoneal Dissemination of Human Scirrhous Gastric Cancer

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Yoshifumi Takei, Misato Takigahira, Keichiro Mihara, Yuzo Tarumi, Kazuyoshi Yanagihara
Journal: Cancer Research
Cancer Res (2011) 71 (4): 1442–1453.
https://doi.org/10.1158/0008-5472.CAN-10-2530
Published: 14 February 2011
View articletitled, The Metastasis-Associated microRNA miR-516a-3p Is a Novel Therapeutic Target for Inhibiting Peritoneal Dissemination of Human Scirrhous Gastric Cancer
Open the PDF for The Metastasis-Associated microRNA miR-516a-3p Is a Novel Therapeutic Target for Inhibiting Peritoneal Dissemination of Human Scirrhous Gastric Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5460: Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition

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Wataru Okamoto, Isamu Okamoto, Takeshi Yoshida, Erina Hatashita, Yuki Yamada, Kiyoko Kuwata, Tokuzo Arao, Kazuyoshi Yanagihara, Kazuto Nishio, Masahiro Fukuoka, Kazuhiko Nakagawa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5460.
https://doi.org/10.1158/1538-7445.AM10-5460
Published: 15 April 2010
View articletitled, Abstract 5460: Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition
Journal Articles

Abstract 2156: Integration of whole genome exon array and array CGH analysis in gastric and colorectal cancer cell lines

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Kazuyuki Furuta, Tokuzo Arao, Kazuko Sakai, Tomoyuki Nagai, Daisuke Tamura, Keiichi Aomatsu, Kanae Kudo, Hiroyasu Kaneda, Yoshihiko Fujita, Kazuko Matsumoto, Yasuhide Yamada, Kazuyoshi Yanagihara, Masaru Sekijima, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2156.
https://doi.org/10.1158/1538-7445.AM10-2156
Published: 15 April 2010
View articletitled, Abstract 2156: Integration of whole genome exon array and array CGH analysis in gastric and colorectal cancer cell lines
Journal Articles

Abstract #1783: Efficacy of RAD001 in peritoneal dissemination of gastric cancer

Free
Fumiko Taguchi, Kazuyoshi Yanagihara, Fumiaki Koizumi
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1783.
Published: 01 May 2009
View articletitled, Abstract #1783: Efficacy of RAD001 in peritoneal dissemination of gastric cancer
Journal Articles

Abstract #2162: SRPX2 is a novel a chondroitin sulfate proteoglycan

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Kaoru Tanaka, Tokuzo Arao, Mari Maegawa, Kazuko Matsumoto, Daisuke Tamura, Keiichi Aomatsu, Kanae Kudo, Hiroyasu Kaneda, Yoshihiko Fujita, Eiko Honda, Kazuyoshi Yanagihara, Yasuhide Yamada, Isamu Okamoto, Kazuhiko Nakagawa, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2162.
Published: 01 May 2009
View articletitled, Abstract #2162: SRPX2 is a novel a chondroitin sulfate proteoglycan
Journal Articles

Antitumor Effect of SN-38–Releasing Polymeric Micelles, NK012, on Spontaneous Peritoneal Metastases from Orthotopic Gastric Cancer in Mice Compared with Irinotecan

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Takako Eguchi Nakajima, Kazuyoshi Yanagihara, Misato Takigahira, Masahiro Yasunaga, Ken Kato, Tetsuya Hamaguchi, Yasuhide Yamada, Yasuhiro Shimada, Keichiro Mihara, Takahiro Ochiya, Yasuhiro Matsumura
Journal: Cancer Research
Cancer Res (2008) 68 (22): 9318–9322.
https://doi.org/10.1158/0008-5472.CAN-08-2822
Published: 14 November 2008
View articletitled, Antitumor Effect of SN-38–Releasing Polymeric Micelles, NK012, on Spontaneous Peritoneal Metastases from Orthotopic Gastric Cancer in Mice Compared with Irinotecan
Open the PDF for Antitumor Effect of SN-38–Releasing Polymeric Micelles, NK012, on Spontaneous Peritoneal Metastases from Orthotopic Gastric Cancer in Mice Compared with Irinotecan in another window
Journal Articles

IMP-3 promotes cellular proliferation activity in gastric cancer.

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Kaoru Tanaka, Tokuzo Arao, Mari Maegawa, Kazuko Matsumoto, Kanae Kudo, Hiroyasu Kaneda, Yoshihiko Fujita, Kazuyoshi Yanagihara, Yasuhide Yamada, Isamu Okamoto, Kazuhiko Nakagawa, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5218.
Published: 01 May 2008
View articletitled, IMP-3 promotes cellular proliferation activity in gastric cancer.
Journal Articles

Antitumor activity of polymeric micelles incorporating SN-38 (NK012) in mouse models of orthotopically planted gastric carcinoma progressing peritoneal dissemination

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Takako Nakajima, Kazuyoshi Yanagihara, Misato Takigahira, Mari Araake, Masahiro Yasunaga, Ken Kato, Tetsuya Hamaguchi, Yasuhide Yamada, Yasuhiro Shimada, Yasuhiro Mastumura
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-109.
Published: 01 May 2008
View articletitled, Antitumor activity of polymeric micelles incorporating SN-38 (NK012) in mouse models of orthotopically planted gastric carcinoma progressing peritoneal dissemination
Journal Articles

SRPX2 is a novel therapeutic target in gastric cancer

Free
Kaoru Tanaka, Tokuzo Arao, Mari Maegawa, Kazuko Matsumoto, Yoshihiko Fujita, Hideyuki Yokote, Kazuyoshi Yanagihara, Yasuhide Yamada, Isamu Okamoto, Kazuhiko Nakagawa, Kazuto Nishio
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1991.
Published: 01 May 2007
View articletitled, SRPX2 is a novel therapeutic target in gastric cancer