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Abstract 6145: Increased PD-L1 expression levels were observed on both tumor cells and macrophages by tocilizumab plus gemcitabine/nab-paclitaxel treatment in gemcitabine/nab-paclitaxel-refractory metastatic pancreatic cancer patients

Kyoko Yamaguchi, Etsuko Fujii, Shuichi Mitsunaga, Noriaki Sawada, Masafumi Ikeda, Takashi Fujitomo, Hideaki Mizuno, Yoko Kayukawa, Mayu Makikawa, Kazunori Aoki, Hiroshi Imaoka, Mitsuhito Sasaki, Kazuo Watanabe, Atsukiko Kato, Hiroyuki Tsunoda, Kimio Terao, Atsushi Ochiai

Cancer Res (2022) 82 (12_Supplement): 6145.

DOI: https://doi.org/10.1158/1538-7445.AM2022-6145

Published: 15 June 2022

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Journal Articles

Abstract CT565: Clinical and translational results of a phase I study, tocilizumab plus gemcitabine/nab-paclitaxel in patient with gemcitabine/nab-paclitaxel-refractory metastatic pancreatic cancer

Shuichi Mitsunaga, Masafumi Ikeda, Kazunori Aoki, Kyoko Yamaguchi, Noriaki Sawada, Etsuko Fujii, Masanobu Nishidate, Takashi Fujitomo, Hideaki Mizuno, Yoko Kayukawa, Atsuhiko Kato, Mayu Makikawa, Hiroshi Imaoka, Mitsuhito Sasaki, Kazuo Watanabe, Hiroyuki Tsunoda, Kimio Terao, Atsushi Ochiai

Cancer Res (2022) 82 (12_Supplement): CT565.

DOI: https://doi.org/10.1158/1538-7445.AM2022-CT565

Published: 15 June 2022

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Journal Articles

IL33 Is a Key Driver of Treatment Resistance of Cancer

Chie Kudo-Saito, Takahiro Miyamoto, Hiroshi Imazeki, Hirokazu Shoji, Kazunori Aoki, Narikazu Boku

Cancer Res (2020) 80 (10): 1981–1990.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-2235

Published: 15 May 2020

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Includes: Supplementary data

Journal Articles

Abstract 3204: Pre-immunization of donor lymphocytes with GITR agonistic antibody enhances antitumor immunity in autologous hematopoietic stem cell transplantation

Kenta Narumi, Marina Henmi, Chihiro Shibasaki, Aya Hirata, Yukihiro Mizoguchi, Kazunori Aoki

Cancer Res (2019) 79 (13_Supplement): 3204.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3204

Published: 01 July 2019

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Journal Articles

Abstract 708: Increase of senescent mesenchymal stromal/stem cells is predictive of unresponsiveness to the treatment with immune checkpoint inhibitors

Chie Kudo-Saito, Takahiro Miyamoto, Mami Kawamura, Yamato Ogiwara, Kazunori Aoki

Cancer Res (2018) 78 (13_Supplement): 708.

DOI: https://doi.org/10.1158/1538-7445.AM2018-708

Published: 01 July 2018

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Journal Articles

Abstract LB-152: Local selivery of GITR agonistic antibody induces a stronger antitumor immunity than systemic administration

Kazunori Aoki, Kenta Narumi, Chihiro Shibasaki, Reina Miyakawa

Cancer Res (2018) 78 (13_Supplement): LB-152.

DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-152

Published: 01 July 2018

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Journal Articles

Abstract 4570: Intratumoral IFN-α gene transfer reduces trafficking of Tregs into tumor by inhibition of CCL17 expression

Kazunori Aoki, Chihiro Shibasaki, Hisayoshi Hashimoto, Kenta Narumi, Chie Kudo

Cancer Res (2017) 77 (13_Supplement): 4570.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4570

Published: 01 July 2017

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Journal Articles

Abstract 4701: Blocking FSTL1 ameliorates immunity against osteosarcoma

Chie Kudo-Saito, Yamato Ogiwara, Kazunori Aoki

Cancer Res (2017) 77 (13_Supplement): 4701.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4701

Published: 01 July 2017

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Journal Articles

Abstract 407: FTY720 suppressed CT26 murine colon cancer peritoneal carcinomatosis progression by decreasing tumor associated macrophages and TNF-alpha

Tomoyoshi Aoyagi, Dorit Avini, Masayuki Nagahashi, Akimitsu Yamada, Krista P. Terracina, Wei-Ching Huang, Kazunori Aoki, Yasunori Matsumoto, Sarah Spiegel, Hisahiro Matsubara, Kazuaki Takabe

Cancer Res (2015) 75 (15_Supplement): 407.

DOI: https://doi.org/10.1158/1538-7445.AM2015-407

Published: 01 August 2015

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Journal Articles

Abstract 2695: FTY720 as a novel therapeutic approach for colon cancer carcinomatosis

Tomoyoshi Aoyagi, Dorit Avini, Masayuki Nagahashi, Akimitsu Yamada, Krista P. Terracina, Wei-Ching Huang, John Soong, Michael O. Idowu, Kazunori Aoki, Sheldon Milstien, Sarah Spiegel, Kazuaki Takabe

Cancer Res (2014) 74 (19_Supplement): 2695.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2695

Published: 01 October 2014

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Journal Articles

Traf2- and Nck-Interacting Kinase Is Essential for Wnt Signaling and Colorectal Cancer Growth

Miki Shitashige, Reiko Satow, Takafumi Jigami, Kazunori Aoki, Kazufumi Honda, Tatsuhiro Shibata, Masaya Ono, Setsuo Hirohashi, Tesshi Yamada

Cancer Res (2010) 70 (12): 5024–5033.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-0306

Published: 14 June 2010

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Includes: Supplementary data

Journal Articles

Identification of genes differentially up-regulated in mouse lung carcinoma utilizing subtractive hybridization

Masayuki Kurooka, Kazunori Aoki, Shigeki Adachi, Taisei Nomura

Cancer Res (2004) 64 (7_Supplement): 363–364.

Published: 01 April 2004

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Journal Articles

Identification of Genes Showing Differential Expression in Antisense K-ras-transduced Pancreatic Cancer Cells with Suppressed Tumorigenicity

Shumpei Ohnami, Nobuyuki Matsumoto, Masaru Nakano, Kazunori Aoki, Koichi Nagasaki, Takashi Sugimura, Masaaki Terada, Teruhiko Yoshida

Cancer Res (1999) 59 (21): 5565–5571.

Published: 01 November 1999

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Journal Articles

Growth Regulation of Human Prostate Cancer Cells by Bone Morphogenetic Protein-2

Hisamitsu Ide, Teruhiko Yoshida, Nobuyuki Matsumoto, Kazunori Aoki, Yukio Osada, Takashi Sugimura, Masaaki Terada

Cancer Res (1997) 57 (22): 5022–5027.

Published: 01 November 1997

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Journal Articles

Liposome-mediated in Vivo Gene Transfer of Antisense K-ras Construct Inhibits Pancreatic Tumor Dissemination in the Murine Peritoneal Cavity

Kazunori Aoki, Teruhiko Yoshida, Takashi Sugimura, Masaaki Terada

Cancer Res (1995) 55 (17): 3810–3816.

Published: 01 September 1995

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NARROW

Abstract 6145: Increased PD-L1 expression levels were observed on both tumor cells and macrophages by tocilizumab plus gemcitabine/nab-paclitaxel treatment in gemcitabine/nab-paclitaxel-refractory metastatic pancreatic cancer patients

Abstract CT565: Clinical and translational results of a phase I study, tocilizumab plus gemcitabine/nab-paclitaxel in patient with gemcitabine/nab-paclitaxel-refractory metastatic pancreatic cancer

IL33 Is a Key Driver of Treatment Resistance of Cancer

Abstract 3204: Pre-immunization of donor lymphocytes with GITR agonistic antibody enhances antitumor immunity in autologous hematopoietic stem cell transplantation

Abstract 708: Increase of senescent mesenchymal stromal/stem cells is predictive of unresponsiveness to the treatment with immune checkpoint inhibitors

Abstract LB-152: Local selivery of GITR agonistic antibody induces a stronger antitumor immunity than systemic administration

Abstract 4570: Intratumoral IFN-α gene transfer reduces trafficking of Tregs into tumor by inhibition of CCL17 expression

Abstract 4701: Blocking FSTL1 ameliorates immunity against osteosarcoma

Abstract 407: FTY720 suppressed CT26 murine colon cancer peritoneal carcinomatosis progression by decreasing tumor associated macrophages and TNF-alpha

Abstract 2695: FTY720 as a novel therapeutic approach for colon cancer carcinomatosis

Traf2- and Nck-Interacting Kinase Is Essential for Wnt Signaling and Colorectal Cancer Growth

Identification of genes differentially up-regulated in mouse lung carcinoma utilizing subtractive hybridization

Identification of Genes Showing Differential Expression in Antisense K-ras-transduced Pancreatic Cancer Cells with Suppressed Tumorigenicity

Growth Regulation of Human Prostate Cancer Cells by Bone Morphogenetic Protein-2

Liposome-mediated in Vivo Gene Transfer of Antisense K-ras Construct Inhibits Pancreatic Tumor Dissemination in the Murine Peritoneal Cavity

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