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Journal Articles

Abstract 2701: iRGD peptide therapy transforms immunosuppressive microenvironment to immune-favorable state in pancreatic ductal adenocarcinoma

Minji Kim, Yoon Ho Choi, Hotaka Kawai, Yukihito Kuroda, Norio Miyamura, Kazuki N. Sugahara, Tae Hyun Hwang

Cancer Res (2025) 85 (8_Supplement_1): 2701.

https://doi.org/10.1158/1538-7445.AM2025-2701

Published: 21 April 2025

View articletitled, Abstract 2701: iRGD peptide therapy transforms immunosuppressive microenvironment to immune-favorable state in pancreatic ductal adenocarcinoma

Journal Articles

Abstract 2698: Altered collagen morphology in pancreatic cancer treated with the iRGD tumor-penetrating peptide

Yoon Ho Choi, Minji Kim, Hotaka Kawai, Yukihito Kuroda, Norio Miyamura, Seock-Jin Chung, Kazuki N. Sugahara, Tae Hyun Hwang

Cancer Res (2025) 85 (8_Supplement_1): 2698.

https://doi.org/10.1158/1538-7445.AM2025-2698

Published: 21 April 2025

View articletitled, Abstract 2698: Altered collagen morphology in pancreatic cancer treated with the iRGD tumor-penetrating peptide

Journal Articles

Abstract 2684: The iRGD tumor-penetrating peptide inhibits TGF-β activation mediated by an αvβ5 integrin-rich tumor microenvironment in pancreatic cancer

Yukihito Kuroda, Kodai Suzuki, Yuki Kunisada, Hotatka Kawai, Henri Havia, Tero A. Järvinen, Moriya Tsuji, Kazuki N. Sugahara

Cancer Res (2025) 85 (8_Supplement_1): 2684.

https://doi.org/10.1158/1538-7445.AM2025-2684

Published: 21 April 2025

View articletitled, Abstract 2684: The iRGD tumor-penetrating peptide inhibits TGF-β activation mediated by an αvβ5 integrin-rich tumor microenvironment in pancreatic cancer

Journal Articles

Abstract 1863: A cytotoxic peptide designed for tumor-targeted delivery of co-injected molecules

Norio Miyamura, Chisato M. Yamazaki, Kyoji Tsuchikama, Kazuki N. Sugahara

Cancer Res (2025) 85 (8_Supplement_1): 1863.

https://doi.org/10.1158/1538-7445.AM2025-1863

Published: 21 April 2025

View articletitled, Abstract 1863: A cytotoxic peptide designed for tumor-targeted delivery of co-injected molecules

Journal Articles

Abstract B059: A novel pancreatic cancer mouse model with human immunity

Norio Miyamura, Kodai Suzuki, Richard A. Friedman, Aristidis Floratos, Yuki Kunisada, Kazuya Masuda, Andrew M. Lowy, Moriya Tsuji, Kazuki N. Sugahara

Cancer Res (2024) 84 (2_Supplement): B059.

https://doi.org/10.1158/1538-7445.PANCA2023-B059

Published: 16 January 2024

View articletitled, Abstract B059: A novel pancreatic cancer mouse model with human immunity

Journal Articles

Abstract B026: αvβ5 Integrin serves as a tumor-specific marker for immunosuppressive regulatory T cells in pancreatic cancer

Yuki Kunisada, Kodai Suzuki, Norio Miyamura, Shingo Eikawa, Tatiana Hurtado de Mendoza, Evangeline S. Mose, Caisheng Lu, Yukihito Kuroda, Erkki Ruoslahti, Andrew M. Lowy, Kazuki N. Sugahara

Cancer Res (2024) 84 (2_Supplement): B026.

https://doi.org/10.1158/1538-7445.PANCA2023-B026

Published: 16 January 2024

View articletitled, Abstract B026: αvβ5 Integrin serves as a tumor-specific marker for immunosuppressive regulatory T cells in pancreatic cancer

Journal Articles

Abstract 385: iRGD mediated delivery of neoantigens to enable immunotherapy in integrin b5-rich tumors

Tatiana Hurtado de Mendoza, Evangeline S. Mose, Gregory P. Botta, Gary B. Braun, Venkata R. Kotamraju, Randall P. French, Kodai Suzuki, Norio Miyamura, Siming Sun, Jay Patel, Tambet Teesalu, Erkki Ruoslahti, Kazuki N. Sugahara, Andrew M. Lowy

Cancer Res (2022) 82 (12_Supplement): 385.

https://doi.org/10.1158/1538-7445.AM2022-385

Published: 15 June 2022

View articletitled, Abstract 385: iRGD mediated delivery of neoantigens to enable immunotherapy in integrin b5-rich tumors

Journal Articles

Abstract LB-062: Targeting of p32 in peritoneal carcinomatosis with intraperitoneal linTT1 peptide-guided pro-apoptotic nanoparticles

Tambet Teesalu, Hunt Hedi, Lorena Simón-Gracia, Allan Tobi, Kazuki N. Sugahara, Shweta Sharma, Erkki Ruoslahti

Cancer Res (2017) 77 (13_Supplement): LB-062.

https://doi.org/10.1158/1538-7445.AM2017-LB-062

Published: 01 July 2017

View articletitled, Abstract LB-062: Targeting of p32 in peritoneal carcinomatosis with intraperitoneal linTT1 peptide-guided pro-apoptotic nanoparticles

Journal Articles

Abstract NG03: A novel endocytic and intercellular transport pathway for drug delivery across blood vessels and into nutrient-deprived tumor cells

Hongbo Pang, Gary B. Braun, Tomas Friman, Pedro Aza-Blanc, Manuel E. Ruidiaz, Kazuki N. Sugahara, Tambet Teesalu, Erkki Ruoslahti

Cancer Res (2015) 75 (15_Supplement): NG03.

https://doi.org/10.1158/1538-7445.AM2015-NG03

Published: 01 August 2015

View articletitled, Abstract NG03: A novel endocytic and intercellular transport pathway for drug delivery across blood vessels and into nutrient-deprived tumor cells

Journal Articles

Abstract C33: N-terminal fragment of Bit1 apoptotic protein induces autophagy in tumor cells

Renwei Chen, Gary B. Braun, Xiuquan Luo, Kazuki N. Sugahara, Tambet Teesalu, Erkki Ruoslahti

Cancer Res (2011) 71 (18_Supplement): C33.

https://doi.org/10.1158/1538-7445.FBCR11-C33

Published: 28 October 2014

View articletitled, Abstract C33: N-terminal fragment of Bit1 apoptotic protein induces autophagy in tumor cells

Journal Articles

Abstract LB-102: A tumor-specific tissue penetrating peptide inhibits metastasis

Kazuki N. Sugahara, Gary B. Braun, Tatiana H. de Mendoza, Venkata R. Kotamraju, Tambet Teesalu, Erkki Ruoslahti, Randall P. French, Andrew M. Lowy

Cancer Res (2014) 74 (19_Supplement): LB-102.

https://doi.org/10.1158/1538-7445.AM2014-LB-102

Published: 01 October 2014

View articletitled, Abstract LB-102: A tumor-specific tissue penetrating peptide inhibits metastasis

Journal Articles

Abstract 5406: The CendR pathway: A novel cell penetration and transcytosis pathway regulated by nutrient availability

Hong-Bo Pang, Gary B. Braun, Tomas Friman, Pedro Aza-Blanc, Manuel E. Ruidiaz, Kazuki N. Sugahara, Tambet Teesalu, Erkki Ruoslahti

Cancer Res (2014) 74 (19_Supplement): 5406.

https://doi.org/10.1158/1538-7445.AM2014-5406

Published: 01 October 2014

View articletitled, Abstract 5406: The CendR pathway: A novel cell penetration and transcytosis pathway regulated by nutrient availability

Journal Articles

Abstract 705: In vivo audition of tumor homing peptides using high-throughput sequencing and q-PCR

Kadri Toome, Tarmo Mölder, Kuldar Kõiv, Pille Säälik, Kazuki N. Sugahara, Erkki Ruoslahti, Tambet Teesalu

Cancer Res (2014) 74 (19_Supplement): 705.

https://doi.org/10.1158/1538-7445.AM2014-705

Published: 01 October 2014

View articletitled, Abstract 705: In vivo audition of tumor homing peptides using high-throughput sequencing and q-PCR

Journal Articles

Abstract 4504: Urokinase plasminogen activator-dependent tumor penetrating peptide

Tambet Teesalu, Kazuki N. Sugahara, Gary B. Braun, Venkata Ramana Kotamraju, Erkki Ruoslahti

Cancer Res (2014) 74 (19_Supplement): 4504.

https://doi.org/10.1158/1538-7445.AM2014-4504

Published: 01 October 2014

View articletitled, Abstract 4504: Urokinase plasminogen activator-dependent tumor penetrating peptide

Journal Articles

Application of a Proapoptotic Peptide to Intratumorally Spreading Cancer Therapy

Renwei Chen, Gary B. Braun, Xiuquan Luo, Kazuki N. Sugahara, Tambet Teesalu, Erkki Ruoslahti

Cancer Res (2013) 73 (4): 1352–1361.

https://doi.org/10.1158/0008-5472.CAN-12-1979

Published: 14 February 2013

View articletitled, Application of a Proapoptotic Peptide to Intratumorally Spreading Cancer Therapy

Includes: Supplementary data

Journal Articles

De Novo Design of a Tumor-Penetrating Peptide

Luca Alberici, Lise Roth, Kazuki N. Sugahara, Lilach Agemy, Venkata R. Kotamraju, Tambet Teesalu, Claudio Bordignon, Catia Traversari, Gian-Paolo Rizzardi, Erkki Ruoslahti

Cancer Res (2013) 73 (2): 804–812.

https://doi.org/10.1158/0008-5472.CAN-12-1668

Published: 16 January 2013

View articletitled, De Novo Design of a Tumor-Penetrating Peptide

Includes: Supplementary data

Journal Articles

Abstract 3703: Nanoparticle-induced targeted pro-apoptotic peptide in glioblastoma

Lilach Agemy, Dinorah Friedmann Morvinski, Venkata Ramana Kotamraju, Kazuki N. Sugahara, Inder M. Verma, Erkki Ruoslahti,

Cancer Res (2010) 70 (8_Supplement): 3703.

https://doi.org/10.1158/1538-7445.AM10-3703

Published: 15 April 2010

View articletitled, Abstract 3703: Nanoparticle-induced targeted pro-apoptotic peptide in glioblastoma

Journal Articles

Chondroitin Sulfate E Fragments Enhance CD44 Cleavage and CD44-Dependent Motility in Tumor Cells

Kazuki N. Sugahara, Takako Hirata, Toshiyuki Tanaka, Shinji Ogino, Mitsuhiro Takeda, Hiroaki Terasawa, Ichio Shimada, Jun-ichi Tamura, Gerdy B. ten Dam, Toin H. van Kuppevelt, Masayuki Miyasaka

Cancer Res (2008) 68 (17): 7191–7199.

https://doi.org/10.1158/0008-5472.CAN-07-6198

Published: 28 August 2008

View articletitled, Chondroitin Sulfate E Fragments Enhance CD44 Cleavage and CD44-Dependent Motility in Tumor Cells

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Abstract 2701: iRGD peptide therapy transforms immunosuppressive microenvironment to immune-favorable state in pancreatic ductal adenocarcinoma

Abstract 2698: Altered collagen morphology in pancreatic cancer treated with the iRGD tumor-penetrating peptide

Abstract 2684: The iRGD tumor-penetrating peptide inhibits TGF-β activation mediated by an αvβ5 integrin-rich tumor microenvironment in pancreatic cancer

Abstract 1863: A cytotoxic peptide designed for tumor-targeted delivery of co-injected molecules

Abstract B059: A novel pancreatic cancer mouse model with human immunity

Abstract B026: αvβ5 Integrin serves as a tumor-specific marker for immunosuppressive regulatory T cells in pancreatic cancer

Abstract 385: iRGD mediated delivery of neoantigens to enable immunotherapy in integrin b5-rich tumors

Abstract LB-062: Targeting of p32 in peritoneal carcinomatosis with intraperitoneal linTT1 peptide-guided pro-apoptotic nanoparticles

Abstract NG03: A novel endocytic and intercellular transport pathway for drug delivery across blood vessels and into nutrient-deprived tumor cells

Abstract C33: N-terminal fragment of Bit1 apoptotic protein induces autophagy in tumor cells

Abstract LB-102: A tumor-specific tissue penetrating peptide inhibits metastasis

Abstract 5406: The CendR pathway: A novel cell penetration and transcytosis pathway regulated by nutrient availability

Abstract 705: In vivo audition of tumor homing peptides using high-throughput sequencing and q-PCR

Abstract 4504: Urokinase plasminogen activator-dependent tumor penetrating peptide

Application of a Proapoptotic Peptide to Intratumorally Spreading Cancer Therapy

De Novo Design of a Tumor-Penetrating Peptide

Abstract 3703: Nanoparticle-induced targeted pro-apoptotic peptide in glioblastoma

Chondroitin Sulfate E Fragments Enhance CD44 Cleavage and CD44-Dependent Motility in Tumor Cells

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